Actinic keratosis - Revision history

Michael at 19:27, 29 November 2023

2023-11-29T19:27:14Z

← Older revision		Revision as of 19:27, 29 November 2023
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			<pre>
			Left Ear Skin Lesion, Biopsy:
			- Hypertrophic squamous lesion, possibly hypertrophic actinic keratosis, see comment.
			- Solar elastosis, marked.

			Comment:
			The lesion has mild basal atypia, proliferative activity and marked hyperkeratosis. The lesion extends to the edge of the tissue and may not be representative of the lesion seen clinically. Clinical correlation is required. Re-excision to rule-out un-sampled pathology should be considered.
			</pre>

			===All uppercase===
	<pre>		<pre>
	SKIN LESION, RIGHT THIGH, BIOPSY:		SKIN LESION, RIGHT THIGH, BIOPSY:

Abraham: /* Histologic subtypes of actinic keratosis */

2018-01-15T06:48:13Z

Histologic subtypes of actinic keratosis

← Older revision		Revision as of 06:48, 15 January 2018
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	*Lichenoid actinic keratosis - band of inflammatory cells at the dermal-epidermal junction.		*Lichenoid actinic keratosis - band of inflammatory cells at the dermal-epidermal junction.
	**DDx: [[lichen planus]].		**DDx: [[lichen planus]].
			*Atrophic actinic keratosis.

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Abraham: /* Gross */

2018-01-15T06:46:40Z

Gross

← Older revision		Revision as of 06:46, 15 January 2018
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	*Yellow-brown scaly, patches.		*Yellow-brown scaly, patches.
	*Sandpaper sensation - on touching.		*Sandpaper sensation - on touching.
	*Usually small (<~~1mc~~), but larger lesions may occur.		*Usually small (<1cm), but larger lesions may occur.
	*May be pigmented.<ref>URL: [http://www.dermoscopy-ids.org/index.php/newest-case/79-lentigo-maligna-vs-pigmented-actinic-keratosis http://www.dermoscopy-ids.org/index.php/newest-case/79-lentigo-maligna-vs-pigmented-actinic-keratosis]. Accessed on: 23 August 2012.</ref>		*May be pigmented.<ref>URL: [http://www.dermoscopy-ids.org/index.php/newest-case/79-lentigo-maligna-vs-pigmented-actinic-keratosis http://www.dermoscopy-ids.org/index.php/newest-case/79-lentigo-maligna-vs-pigmented-actinic-keratosis]. Accessed on: 23 August 2012.</ref>

Abraham: /* Gross */

2018-01-15T06:46:30Z

Gross

← Older revision		Revision as of 06:46, 15 January 2018
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	*Yellow-brown scaly, patches.		*Yellow-brown scaly, patches.
	*Sandpaper sensation - on touching.		*Sandpaper sensation - on touching.
			*Usually small (<1mc), but larger lesions may occur.
	*May be pigmented.<ref>URL: [http://www.dermoscopy-ids.org/index.php/newest-case/79-lentigo-maligna-vs-pigmented-actinic-keratosis http://www.dermoscopy-ids.org/index.php/newest-case/79-lentigo-maligna-vs-pigmented-actinic-keratosis]. Accessed on: 23 August 2012.</ref>		*May be pigmented.<ref>URL: [http://www.dermoscopy-ids.org/index.php/newest-case/79-lentigo-maligna-vs-pigmented-actinic-keratosis http://www.dermoscopy-ids.org/index.php/newest-case/79-lentigo-maligna-vs-pigmented-actinic-keratosis]. Accessed on: 23 August 2012.</ref>

Abraham: /* Microscopic */

2018-01-15T06:45:21Z

Microscopic

← Older revision		Revision as of 06:45, 15 January 2018
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	*[[Seborrheic keratosis]] - should not have basilar nuclear atypia.		*[[Seborrheic keratosis]] - should not have basilar nuclear atypia.
	*[[Lichenoid keratosis]] (esp. for ''lichenoid actinic keratosis'') - has a band of inflammatory cells in the superficial dermis.		*[[Lichenoid keratosis]] (esp. for ''lichenoid actinic keratosis'') - has a band of inflammatory cells in the superficial dermis.
	*[[Discoid Luphus Erythematosus]].		*Discoid Luphus Erythematosus.

	===Images===		===Images===

Abraham: /* Microscopic */

2018-01-15T06:44:50Z

Microscopic

← Older revision		Revision as of 06:44, 15 January 2018
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	*[[Seborrheic keratosis]] - should not have basilar nuclear atypia.		*[[Seborrheic keratosis]] - should not have basilar nuclear atypia.
	*[[Lichenoid keratosis]] (esp. for ''lichenoid actinic keratosis'') - has a band of inflammatory cells in the superficial dermis.		*[[Lichenoid keratosis]] (esp. for ''lichenoid actinic keratosis'') - has a band of inflammatory cells in the superficial dermis.
			*[[Discoid Luphus Erythematosus]].

	===Images===		===Images===

Michael: /* Images */

2013-12-18T02:38:20Z

Images

← Older revision		Revision as of 02:38, 18 December 2013
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	Image:SkinTumors-P5280065.JPG \| Actinic keratosis. (WC)		Image:SkinTumors-P5280065.JPG \| Actinic keratosis. (WC)
	Image:SkinTumors-P5280055.JPG \| Actinic keartosis. (WC)		Image:SkinTumors-P5280055.JPG \| Actinic keartosis. (WC)
			Image:SkinTumors-P5280056.JPG \| Actinic keratosis. (WC)
			</gallery>
			<gallery>
	Image:Bowenoid_actinic_keratosis_-_high_mag.jpg \| Bowenoid actinic keratosis - high mag. (WC)		Image:Bowenoid_actinic_keratosis_-_high_mag.jpg \| Bowenoid actinic keratosis - high mag. (WC)
	Image:Bowenoid_actinic_keratosis_-_very_high_mag.jpg \| Bowenoid actinic keratosis - very high mag. (WC)		Image:Bowenoid_actinic_keratosis_-_very_high_mag.jpg \| Bowenoid actinic keratosis - very high mag. (WC)
	</gallery>		</gallery>

	===Histologic subtypes of actinic keratosis===		===Histologic subtypes of actinic keratosis===
	Like most common things, there are several variants:<ref name=Ref_Derm353>{{Ref Derm\|353}}</ref>		Like most common things, there are several variants:<ref name=Ref_Derm353>{{Ref Derm\|353}}</ref>

Michael: /* Micro */

2013-10-29T21:22:25Z

Micro

← Older revision		Revision as of 21:22, 29 October 2013
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	There is no clefting of the lesion from the surrounding stroma. Intercellular bridges are identified.		There is no clefting of the lesion from the surrounding stroma. Intercellular bridges are identified.

			=====Lichenoid AK=====
			The sections show skin with a lymphoplasmacytic interface dermatitis, hypergranulosis, hyperkeratosis, loss of the rete ridges and apoptotic keratinocytes. The epidermis matures to the surface; however, there is basal cell hyperplasia associated with moderate keratinocyte nuclear atypia (including hyperchromasia and anisonucleosis). Pigment incontinence is present. Solar elastosis is present. The lesion is completely excised in the plane of section.

	==See also==		==See also==

Michael: /* Histologic subtypes of actinic keratosis */

2013-10-29T21:12:01Z

Histologic subtypes of actinic keratosis

← Older revision		Revision as of 21:12, 29 October 2013
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	*Pigmented actinic keratosis.		*Pigmented actinic keratosis.
	**DDx: [[lentigo maligna]].		**DDx: [[lentigo maligna]].
	*Lichenoid actinic keratosis.		*Lichenoid actinic keratosis - band of inflammatory cells at the dermal-epidermal junction.
			**DDx: [[lichen planus]].

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Michael: /* Microscopic */

2013-10-25T11:58:39Z

Microscopic

← Older revision		Revision as of 11:58, 25 October 2013
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	**One should see benign melanocytes within an AK... otherwise one should do stains as the melanocytes may be mimicking keratinocytes.		**One should see benign melanocytes within an AK... otherwise one should do stains as the melanocytes may be mimicking keratinocytes.
	*[[Seborrheic keratosis]] - should not have basilar nuclear atypia.		*[[Seborrheic keratosis]] - should not have basilar nuclear atypia.
			*[[Lichenoid keratosis]] (esp. for ''lichenoid actinic keratosis'') - has a band of inflammatory cells in the superficial dermis.

	===Images===		===Images===

← Older revision		Revision as of 02:38, 18 December 2013
Line 72:		Line 72:
	Image:SkinTumors-P5280065.JPG \| Actinic keratosis. (WC)		Image:SkinTumors-P5280065.JPG \| Actinic keratosis. (WC)
	Image:SkinTumors-P5280055.JPG \| Actinic keartosis. (WC)		Image:SkinTumors-P5280055.JPG \| Actinic keartosis. (WC)
			Image:SkinTumors-P5280056.JPG \| Actinic keratosis. (WC)
			</gallery>
			<gallery>
	Image:Bowenoid_actinic_keratosis_-_high_mag.jpg \| Bowenoid actinic keratosis - high mag. (WC)		Image:Bowenoid_actinic_keratosis_-_high_mag.jpg \| Bowenoid actinic keratosis - high mag. (WC)
	Image:Bowenoid_actinic_keratosis_-_very_high_mag.jpg \| Bowenoid actinic keratosis - very high mag. (WC)		Image:Bowenoid_actinic_keratosis_-_very_high_mag.jpg \| Bowenoid actinic keratosis - very high mag. (WC)
	</gallery>		</gallery>

	===Histologic subtypes of actinic keratosis===		===Histologic subtypes of actinic keratosis===
	Like most common things, there are several variants:<ref name=Ref_Derm353>{{Ref Derm\|353}}</ref>		Like most common things, there are several variants:<ref name=Ref_Derm353>{{Ref Derm\|353}}</ref>