Ameloblastoma - Revision history

Michael: /* General */

2022-05-26T17:31:45Z

General

← Older revision		Revision as of 17:31, 26 May 2022
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	*Osteous lesion.		*Osteous lesion.
	*Usually mandible.<ref>URL: [http://www.waent.org/archives/2010/Vol3-2/20100618-ameloblastoma/jaw-tumor.htm http://www.waent.org/archives/2010/Vol3-2/20100618-ameloblastoma/jaw-tumor.htm]. Accessed on: 30 November 2011.</ref>		*Usually mandible.<ref>URL: [http://www.waent.org/archives/2010/Vol3-2/20100618-ameloblastoma/jaw-tumor.htm http://www.waent.org/archives/2010/Vol3-2/20100618-ameloblastoma/jaw-tumor.htm]. Accessed on: 30 November 2011.</ref>
	**In a review of 3677 cases, the mandible-to-maxilla ratio was 5 to 1.<ref name=pmid7633291>{{Cite journal \| last1 = Reichart \| first1 = PA. \| last2 = Philipsen \| first2 = HP. \| last3 = Sonner \| first3 = S. \| title = Ameloblastoma: biological profile of 3677 cases. \| journal = Eur J Cancer B Oral Oncol \| volume = 31B \| issue = 2 \| pages = 86-99 \| month = Mar \| year = 1995 \| doi = \| PMID = 7633291 }}</ref>		**In a review of 3677 cases, the mandible-to-[[maxilla]] ratio was 5 to 1.<ref name=pmid7633291>{{Cite journal \| last1 = Reichart \| first1 = PA. \| last2 = Philipsen \| first2 = HP. \| last3 = Sonner \| first3 = S. \| title = Ameloblastoma: biological profile of 3677 cases. \| journal = Eur J Cancer B Oral Oncol \| volume = 31B \| issue = 2 \| pages = 86-99 \| month = Mar \| year = 1995 \| doi = \| PMID = 7633291 }}</ref>
	*May arise from an odontogenic cyst,<ref name=pmid10587275>{{Cite journal \| last1 = Eversole \| first1 = LR. \| title = Malignant epithelial odontogenic tumors. \| journal = Semin Diagn Pathol \| volume = 16 \| issue = 4 \| pages = 317-24 \| month = Nov \| year = 1999 \| doi = \| PMID = 10587275 }}</ref> e.g. [[dentigerous cyst]].<ref name=pmid21957386>{{Cite journal \| last1 = Moosvi \| first1 = Z. \| last2 = Tayaar \| first2 = SA. \| last3 = Kumar \| first3 = GS. \| title = Neoplastic potential of odontogenic cysts. \| journal = Contemp Clin Dent \| volume = 2 \| issue = 2 \| pages = 106-9 \| month = Apr \| year = 2011 \| doi = 10.4103/0976-237X.83073 \| PMID = 21957386 \| PMC = 3180832 }}</ref>		*May arise from an odontogenic cyst,<ref name=pmid10587275>{{Cite journal \| last1 = Eversole \| first1 = LR. \| title = Malignant epithelial odontogenic tumors. \| journal = Semin Diagn Pathol \| volume = 16 \| issue = 4 \| pages = 317-24 \| month = Nov \| year = 1999 \| doi = \| PMID = 10587275 }}</ref> e.g. [[dentigerous cyst]].<ref name=pmid21957386>{{Cite journal \| last1 = Moosvi \| first1 = Z. \| last2 = Tayaar \| first2 = SA. \| last3 = Kumar \| first3 = GS. \| title = Neoplastic potential of odontogenic cysts. \| journal = Contemp Clin Dent \| volume = 2 \| issue = 2 \| pages = 106-9 \| month = Apr \| year = 2011 \| doi = 10.4103/0976-237X.83073 \| PMID = 21957386 \| PMC = 3180832 }}</ref>
	*Can be malignant<ref name=pmid15454770>{{Cite journal \| last1 = Goldenberg \| first1 = D. \| last2 = Sciubba \| first2 = J. \| last3 = Koch \| first3 = W. \| last4 = Tufano \| first4 = RP. \| title = Malignant odontogenic tumors: a 22-year experience. \| journal = Laryngoscope \| volume = 114 \| issue = 10 \| pages = 1770-4 \| month = Oct \| year = 2004 \| doi = 10.1097/00005537-200410000-00018 \| PMID = 15454770 }}</ref> - rare.<ref name=pmid23775022>{{Cite journal \| last1 = Chou \| first1 = YH. \| last2 = Jhuang \| first2 = JY. \| last3 = Chang \| first3 = MH. \| last4 = Huang \| first4 = WC. \| last5 = Hsieh \| first5 = MS. \| title = Metastasizing Ameloblastoma With Localized Interstitial Spread in the Lung: Report of Two Cases. \| journal = Int J Surg Pathol \| volume = \| issue = \| pages = \| month = Jun \| year = 2013 \| doi = 10.1177/1066896913491321 \| PMID = 23775022 }}</ref>		*Can be malignant<ref name=pmid15454770>{{Cite journal \| last1 = Goldenberg \| first1 = D. \| last2 = Sciubba \| first2 = J. \| last3 = Koch \| first3 = W. \| last4 = Tufano \| first4 = RP. \| title = Malignant odontogenic tumors: a 22-year experience. \| journal = Laryngoscope \| volume = 114 \| issue = 10 \| pages = 1770-4 \| month = Oct \| year = 2004 \| doi = 10.1097/00005537-200410000-00018 \| PMID = 15454770 }}</ref> - rare.<ref name=pmid23775022>{{Cite journal \| last1 = Chou \| first1 = YH. \| last2 = Jhuang \| first2 = JY. \| last3 = Chang \| first3 = MH. \| last4 = Huang \| first4 = WC. \| last5 = Hsieh \| first5 = MS. \| title = Metastasizing Ameloblastoma With Localized Interstitial Spread in the Lung: Report of Two Cases. \| journal = Int J Surg Pathol \| volume = \| issue = \| pages = \| month = Jun \| year = 2013 \| doi = 10.1177/1066896913491321 \| PMID = 23775022 }}</ref>

Brigitte: /* Images */

2018-04-04T12:53:57Z

Images

← Older revision		Revision as of 12:53, 4 April 2018
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	===Images===		===Images===
	~~www:~~
	*[http://www.estomatologia.com.br/diagnosticos_det2.asp?cod_diag=12 Ameloblastoma - several images (estomatologia.com.br)].
	*[http://www.cytochemistry.net/microanatomy/digestive/devtooth9.jpg Stellate reticulum (cytochemistry.net)].

	<gallery>		<gallery>

Michael at 15:28, 23 February 2014

2014-02-23T15:28:28Z

← Older revision		Revision as of 15:28, 23 February 2014
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	\| Tx =		\| Tx =
	}}		}}
	'''Ameloblastoma''' is an [[odontogenic ~~cyst~~]].		'''Ameloblastoma''' is an [[odontogenic tumour]].

	==General==		==General==

Michael: /* Gross */

2014-02-23T15:28:07Z

Gross

← Older revision		Revision as of 15:28, 23 February 2014
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	==Gross==		==Gross==
	*Mass - usu. mandible or maxilla.<ref name=pmid23775022/>		*Mass - usu. mandible or maxilla.<ref name=pmid23775022/>
			**Mandile most common.

	==Microscopic==		==Microscopic==

Michael at 15:27, 23 February 2014

2014-02-23T15:27:24Z

← Older revision		Revision as of 15:27, 23 February 2014
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	\| Rads =		\| Rads =
	\| Endoscopy =		\| Endoscopy =
	\| Prognosis =		\| Prognosis = locally aggresive, rarely malignant
	\| Other =		\| Other =
	\| ClinDDx = [[keratocystic odontogenic tumour]], odontogenic cysts		\| ClinDDx = [[keratocystic odontogenic tumour]], odontogenic cysts

Michael: tweak

2014-02-23T15:26:50Z

tweak

← Older revision		Revision as of 15:26, 23 February 2014
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	**In a review of 3677 cases, the mandible-to-maxilla ratio was 5 to 1.<ref name=pmid7633291>{{Cite journal \| last1 = Reichart \| first1 = PA. \| last2 = Philipsen \| first2 = HP. \| last3 = Sonner \| first3 = S. \| title = Ameloblastoma: biological profile of 3677 cases. \| journal = Eur J Cancer B Oral Oncol \| volume = 31B \| issue = 2 \| pages = 86-99 \| month = Mar \| year = 1995 \| doi = \| PMID = 7633291 }}</ref>		**In a review of 3677 cases, the mandible-to-maxilla ratio was 5 to 1.<ref name=pmid7633291>{{Cite journal \| last1 = Reichart \| first1 = PA. \| last2 = Philipsen \| first2 = HP. \| last3 = Sonner \| first3 = S. \| title = Ameloblastoma: biological profile of 3677 cases. \| journal = Eur J Cancer B Oral Oncol \| volume = 31B \| issue = 2 \| pages = 86-99 \| month = Mar \| year = 1995 \| doi = \| PMID = 7633291 }}</ref>
	*May arise from an odontogenic cyst,<ref name=pmid10587275>{{Cite journal \| last1 = Eversole \| first1 = LR. \| title = Malignant epithelial odontogenic tumors. \| journal = Semin Diagn Pathol \| volume = 16 \| issue = 4 \| pages = 317-24 \| month = Nov \| year = 1999 \| doi = \| PMID = 10587275 }}</ref> e.g. [[dentigerous cyst]].<ref name=pmid21957386>{{Cite journal \| last1 = Moosvi \| first1 = Z. \| last2 = Tayaar \| first2 = SA. \| last3 = Kumar \| first3 = GS. \| title = Neoplastic potential of odontogenic cysts. \| journal = Contemp Clin Dent \| volume = 2 \| issue = 2 \| pages = 106-9 \| month = Apr \| year = 2011 \| doi = 10.4103/0976-237X.83073 \| PMID = 21957386 \| PMC = 3180832 }}</ref>		*May arise from an odontogenic cyst,<ref name=pmid10587275>{{Cite journal \| last1 = Eversole \| first1 = LR. \| title = Malignant epithelial odontogenic tumors. \| journal = Semin Diagn Pathol \| volume = 16 \| issue = 4 \| pages = 317-24 \| month = Nov \| year = 1999 \| doi = \| PMID = 10587275 }}</ref> e.g. [[dentigerous cyst]].<ref name=pmid21957386>{{Cite journal \| last1 = Moosvi \| first1 = Z. \| last2 = Tayaar \| first2 = SA. \| last3 = Kumar \| first3 = GS. \| title = Neoplastic potential of odontogenic cysts. \| journal = Contemp Clin Dent \| volume = 2 \| issue = 2 \| pages = 106-9 \| month = Apr \| year = 2011 \| doi = 10.4103/0976-237X.83073 \| PMID = 21957386 \| PMC = 3180832 }}</ref>
	*Can be malignant<ref name=pmid15454770>{{Cite journal \| last1 = Goldenberg \| first1 = D. \| last2 = Sciubba \| first2 = J. \| last3 = Koch \| first3 = W. \| last4 = Tufano \| first4 = RP. \| title = Malignant odontogenic tumors: a 22-year experience. \| journal = Laryngoscope \| volume = 114 \| issue = 10 \| pages = 1770-4 \| month = Oct \| year = 2004 \| doi = 10.1097/00005537-200410000-00018 \| PMID = 15454770 }}</ref> - rare.<ref name=pmid23775022>{{Cite journal \| last1 = Chou \| first1 = YH. \| last2 = Jhuang \| first2 = JY. \| last3 = Chang \| first3 = MH. \| last4 = Huang \| first4 = WC. \| last5 = Hsieh \| first5 = MS. \| title = Metastasizing Ameloblastoma With Localized Interstitial Spread in the Lung: Report of Two Cases. \| journal = Int J Surg Pathol \| volume = \| issue = \| pages = \| month = Jun \| year = 2013 \| doi = 10.1177/1066896913491321 \| PMID = 23775022 }}		*Can be malignant<ref name=pmid15454770>{{Cite journal \| last1 = Goldenberg \| first1 = D. \| last2 = Sciubba \| first2 = J. \| last3 = Koch \| first3 = W. \| last4 = Tufano \| first4 = RP. \| title = Malignant odontogenic tumors: a 22-year experience. \| journal = Laryngoscope \| volume = 114 \| issue = 10 \| pages = 1770-4 \| month = Oct \| year = 2004 \| doi = 10.1097/00005537-200410000-00018 \| PMID = 15454770 }}</ref> - rare.<ref name=pmid23775022>{{Cite journal \| last1 = Chou \| first1 = YH. \| last2 = Jhuang \| first2 = JY. \| last3 = Chang \| first3 = MH. \| last4 = Huang \| first4 = WC. \| last5 = Hsieh \| first5 = MS. \| title = Metastasizing Ameloblastoma With Localized Interstitial Spread in the Lung: Report of Two Cases. \| journal = Int J Surg Pathol \| volume = \| issue = \| pages = \| month = Jun \| year = 2013 \| doi = 10.1177/1066896913491321 \| PMID = 23775022 }}</ref>
	</ref>

	===Classification===		===Classification===
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	#*Unlikely to reoccur.		#*Unlikely to reoccur.
	#*Classically found in younger individuals.		#*Classically found in younger individuals.

			==Gross==
			*Mass - usu. mandible or maxilla.<ref name=pmid23775022/>

	==Microscopic==		==Microscopic==

Michael: /* General */

2014-02-23T15:25:53Z

General

← Older revision		Revision as of 15:25, 23 February 2014
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	**In a review of 3677 cases, the mandible-to-maxilla ratio was 5 to 1.<ref name=pmid7633291>{{Cite journal \| last1 = Reichart \| first1 = PA. \| last2 = Philipsen \| first2 = HP. \| last3 = Sonner \| first3 = S. \| title = Ameloblastoma: biological profile of 3677 cases. \| journal = Eur J Cancer B Oral Oncol \| volume = 31B \| issue = 2 \| pages = 86-99 \| month = Mar \| year = 1995 \| doi = \| PMID = 7633291 }}</ref>		**In a review of 3677 cases, the mandible-to-maxilla ratio was 5 to 1.<ref name=pmid7633291>{{Cite journal \| last1 = Reichart \| first1 = PA. \| last2 = Philipsen \| first2 = HP. \| last3 = Sonner \| first3 = S. \| title = Ameloblastoma: biological profile of 3677 cases. \| journal = Eur J Cancer B Oral Oncol \| volume = 31B \| issue = 2 \| pages = 86-99 \| month = Mar \| year = 1995 \| doi = \| PMID = 7633291 }}</ref>
	*May arise from an odontogenic cyst,<ref name=pmid10587275>{{Cite journal \| last1 = Eversole \| first1 = LR. \| title = Malignant epithelial odontogenic tumors. \| journal = Semin Diagn Pathol \| volume = 16 \| issue = 4 \| pages = 317-24 \| month = Nov \| year = 1999 \| doi = \| PMID = 10587275 }}</ref> e.g. [[dentigerous cyst]].<ref name=pmid21957386>{{Cite journal \| last1 = Moosvi \| first1 = Z. \| last2 = Tayaar \| first2 = SA. \| last3 = Kumar \| first3 = GS. \| title = Neoplastic potential of odontogenic cysts. \| journal = Contemp Clin Dent \| volume = 2 \| issue = 2 \| pages = 106-9 \| month = Apr \| year = 2011 \| doi = 10.4103/0976-237X.83073 \| PMID = 21957386 \| PMC = 3180832 }}</ref>		*May arise from an odontogenic cyst,<ref name=pmid10587275>{{Cite journal \| last1 = Eversole \| first1 = LR. \| title = Malignant epithelial odontogenic tumors. \| journal = Semin Diagn Pathol \| volume = 16 \| issue = 4 \| pages = 317-24 \| month = Nov \| year = 1999 \| doi = \| PMID = 10587275 }}</ref> e.g. [[dentigerous cyst]].<ref name=pmid21957386>{{Cite journal \| last1 = Moosvi \| first1 = Z. \| last2 = Tayaar \| first2 = SA. \| last3 = Kumar \| first3 = GS. \| title = Neoplastic potential of odontogenic cysts. \| journal = Contemp Clin Dent \| volume = 2 \| issue = 2 \| pages = 106-9 \| month = Apr \| year = 2011 \| doi = 10.4103/0976-237X.83073 \| PMID = 21957386 \| PMC = 3180832 }}</ref>
			*Can be malignant<ref name=pmid15454770>{{Cite journal \| last1 = Goldenberg \| first1 = D. \| last2 = Sciubba \| first2 = J. \| last3 = Koch \| first3 = W. \| last4 = Tufano \| first4 = RP. \| title = Malignant odontogenic tumors: a 22-year experience. \| journal = Laryngoscope \| volume = 114 \| issue = 10 \| pages = 1770-4 \| month = Oct \| year = 2004 \| doi = 10.1097/00005537-200410000-00018 \| PMID = 15454770 }}</ref> - rare.<ref name=pmid23775022>{{Cite journal \| last1 = Chou \| first1 = YH. \| last2 = Jhuang \| first2 = JY. \| last3 = Chang \| first3 = MH. \| last4 = Huang \| first4 = WC. \| last5 = Hsieh \| first5 = MS. \| title = Metastasizing Ameloblastoma With Localized Interstitial Spread in the Lung: Report of Two Cases. \| journal = Int J Surg Pathol \| volume = \| issue = \| pages = \| month = Jun \| year = 2013 \| doi = 10.1177/1066896913491321 \| PMID = 23775022 }}
			</ref>

	===Classification===		===Classification===

Michael at 15:16, 23 February 2014

2014-02-23T15:16:22Z

← Older revision		Revision as of 15:16, 23 February 2014
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	\| Prognosis =		\| Prognosis =
	\| Other =		\| Other =
	\| ClinDDx = [[~~keratocytic~~ odontogenic tumour]], odontogenic cysts		\| ClinDDx = [[keratocystic odontogenic tumour]], odontogenic cysts
	\| Tx =		\| Tx =
	}}		}}


	'''Ameloblastoma''' is an [[odontogenic cyst]].		'''Ameloblastoma''' is an [[odontogenic cyst]].

Michael: +infobox

2014-02-23T15:15:47Z

+infobox

← Older revision		Revision as of 15:15, 23 February 2014
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			{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image = Ameloblastoma - high mag.jpg
			\| Width =
			\| Caption = Ameloblastoma. [[H&E stain]].
			\| Synonyms =
			\| Micro = stellate reticulum (star-shaped cells), tall columnar cells that have palisaded nuclei with reverse polarization, subnuclear vacuolization, +/-giant cells, +/-subepithelial hyalinization (eosinophilic acellular amorphous material)
			\| Subtypes = solid/multicystic, unicystic
			\| LMDDx = [[adenomatoid odontogenic tumour]], [[ameloblastic fibroma]]
			\| Stains =
			\| IHC =
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross =
			\| Grossing =
			\| Site = usu. mandible - see ''[[odontogenic tumours and cysts]]''
			\| Assdx =
			\| Syndromes =
			\| Clinicalhx =
			\| Signs =
			\| Symptoms =
			\| Prevalence = uncommon
			\| Bloodwork =
			\| Rads =
			\| Endoscopy =
			\| Prognosis =
			\| Other =
			\| ClinDDx = [[keratocytic odontogenic tumour]], odontogenic cysts
			\| Tx =
			}}


	'''Ameloblastoma''' is an [[odontogenic cyst]].		'''Ameloblastoma''' is an [[odontogenic cyst]].

Michael: split out

2014-02-23T15:08:20Z

split out

← Older revision		Revision as of 15:08, 23 February 2014
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	~~#redirect~~ [[~~Odontogenic tumours and cysts#Ameloblastoma~~]]		'''Ameloblastoma''' is an [[odontogenic cyst]].

			==General==
			*Osteous lesion.
			*Usually mandible.<ref>URL: [http://www.waent.org/archives/2010/Vol3-2/20100618-ameloblastoma/jaw-tumor.htm http://www.waent.org/archives/2010/Vol3-2/20100618-ameloblastoma/jaw-tumor.htm]. Accessed on: 30 November 2011.</ref>
			**In a review of 3677 cases, the mandible-to-maxilla ratio was 5 to 1.<ref name=pmid7633291>{{Cite journal \| last1 = Reichart \| first1 = PA. \| last2 = Philipsen \| first2 = HP. \| last3 = Sonner \| first3 = S. \| title = Ameloblastoma: biological profile of 3677 cases. \| journal = Eur J Cancer B Oral Oncol \| volume = 31B \| issue = 2 \| pages = 86-99 \| month = Mar \| year = 1995 \| doi = \| PMID = 7633291 }}</ref>
			*May arise from an odontogenic cyst,<ref name=pmid10587275>{{Cite journal \| last1 = Eversole \| first1 = LR. \| title = Malignant epithelial odontogenic tumors. \| journal = Semin Diagn Pathol \| volume = 16 \| issue = 4 \| pages = 317-24 \| month = Nov \| year = 1999 \| doi = \| PMID = 10587275 }}</ref> e.g. [[dentigerous cyst]].<ref name=pmid21957386>{{Cite journal \| last1 = Moosvi \| first1 = Z. \| last2 = Tayaar \| first2 = SA. \| last3 = Kumar \| first3 = GS. \| title = Neoplastic potential of odontogenic cysts. \| journal = Contemp Clin Dent \| volume = 2 \| issue = 2 \| pages = 106-9 \| month = Apr \| year = 2011 \| doi = 10.4103/0976-237X.83073 \| PMID = 21957386 \| PMC = 3180832 }}</ref>

			===Classification===
			Location:
			#Intra-osseous.
			#*Locally aggressive.
			#Peripheral.
			#*Benign.

			====Subclassification of intra-osseous type====
			Histology:
			#Solid/multicystic.
			#*More commonly reoccur.
			#Unicystic.
			#*Unlikely to reoccur.
			#*Classically found in younger individuals.

			==Microscopic==
			Features:<ref>URL: [http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970616-7 http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970616-7]. Accessed on: March 9, 2010.</ref>
			*Stellate reticulum - star-shaped cells, found in a developing tooth.
			*Tall columnar cells.
			**Palisaded nuclei with reverse polarization.
			***Reverse polarization of nuclei = nuclei distant from the basement membrane/nuclei at pole opposite of basement membrane.
			***Palisaded nuclei = picket fence appearance; columnar-shaped nuclei with long axis perpendicular to the basement membrane -- '''key feature'''.
			**Subnuclear vacuolization.
			*+/-Giant cells.
			*+/-Subepithelial hyalinization (eosinophilic acellular amorphous material).
			**Seen deep to the basement membrane.
			*Variable morphology (see below - ''morphology'').

			DDx (nuclear palisading):
			*[[Adenomatoid odontogenic tumour]].
			*[[Ameloblastic fibroma]].

			===Images===
			www:
			*[http://www.estomatologia.com.br/diagnosticos_det2.asp?cod_diag=12 Ameloblastoma - several images (estomatologia.com.br)].
			*[http://www.cytochemistry.net/microanatomy/digestive/devtooth9.jpg Stellate reticulum (cytochemistry.net)].

			<gallery>
			Image: Ameloblastoma - low mag.jpg \| Ameloblastoma - low mag. (WC)
			Image: Ameloblastoma - intermed mag.jpg \| Ameloblastoma - intermed. mag. (WC)
			Image: Ameloblastoma - high mag.jpg \| Ameloblastoma - high mag. (WC)
			Image: Ameloblastoma - very high mag.jpg \| Ameloblastoma - very high mag. (WC)
			</gallery>

			===Morphology===
			*Not prognostic.

			Morphologic variants:
			*Follicular ameloblastoma (classic appearance).
			*Plexiform ameloblastoma (does not have prominent palisading).
			*Acanthomatous ameloblastoma.
			*Desmoplastic ameloblastoma.
			*Basaloid ameloblastoma.

			==See also==
			*[[Odontogenic tumours and cysts]].

			==References==
			{{Reflist\|2}}

			[[Category:Odontogenic tumours and cysts]]
	[[Category:Diagnosis]]		[[Category:Diagnosis]]