An introduction to gynecologic pathology - Revision history

Michael: /* Hilus cells */

2017-07-24T15:00:45Z

Hilus cells

← Older revision		Revision as of 15:00, 24 July 2017
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	**Round nucleus +/- nucleolus.		**Round nucleus +/- nucleolus.

	Images:		====Images====
	*[http://path.upmc.edu/cases/case394.html Hilus cell hyperplasia (upmc.edu)].		*[http://path.upmc.edu/cases/case394.html Hilus cell hyperplasia (upmc.edu)].

			===IHC===
			Features:
			*Inhibin +ve.
			*Calretinin +ve.
			*PLAP -ve.

	==Mesonephric duct remnant==		==Mesonephric duct remnant==

Michael: /* Benign stuff */

2017-07-24T14:59:35Z

Benign stuff

← Older revision		Revision as of 14:59, 24 July 2017
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	\| [[FATWO]], [[mesonephric adenocarcinoma]]		\| [[FATWO]], [[mesonephric adenocarcinoma]]
	\| Develops into vas deferens in males.		\| Develops into vas deferens in males.
	\| [[Image:Mesonephric duct remnant -- intermed mag.jpg\|100px\|thumb\|center\|~~MDR~~ (WC)]]		\| [[Image:Mesonephric duct remnant -- intermed mag.jpg\|100px\|thumb\|center\|MR (WC)]]
	\|-		\|-
	\|[[Walthard cell rest]]		\|[[Walthard cell rest]]

Michael: /* Benign stuff */

2017-07-24T14:59:16Z

Benign stuff

← Older revision		Revision as of 14:59, 24 July 2017
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	\| [[FATWO]], [[mesonephric adenocarcinoma]]		\| [[FATWO]], [[mesonephric adenocarcinoma]]
	\| Develops into vas deferens in males.		\| Develops into vas deferens in males.
	\| <!-- ~~[http://www.uoguelph.ca/~rfoster/repropath/surgicalpath/female/cat/F%20fel%20anomaly%20mesonephric%20remnants%20YB108065%2011wl~~.jpg ~~mesonephric r., cat~~ (~~uoguelph.ca~~)] ~~-->~~		\| [[Image:Mesonephric duct remnant -- intermed mag.jpg\|100px\|thumb\|center\|MDR (WC)]]
	\|-		\|-
	\|[[Walthard cell rest]]		\|[[Walthard cell rest]]
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	\| [[Brenner tumour]]		\| [[Brenner tumour]]
	\| nil		\| nil
	\| [~~http://commons.wikimedia.org/wiki/File~~:Walthard_cell_rest_-_very_high_mag.jpg ~~Coffee bean n.~~ (WC)], [~~http://commons.wikimedia.org/wiki/File~~:Walthard_cell_rest_-_very_low_mag.jpg WCR (WC)]		\|[[Image:Walthard_cell_rest_-_very_high_mag.jpg\|thumb\|center\|100px\|WCR (WC)]][[Image:Walthard_cell_rest_-_very_low_mag.jpg\|thumb\|center\|100px\|WCR (WC)]]
	\|}		\|}

Michael: /* Benign stuff */

2017-07-24T14:12:34Z

Benign stuff

← Older revision		Revision as of 14:12, 24 July 2017
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	\| [[FATWO]], [[mesonephric adenocarcinoma]]		\| [[FATWO]], [[mesonephric adenocarcinoma]]
	\| Develops into vas deferens in males.		\| Develops into vas deferens in males.
	\| [http://www.uoguelph.ca/~rfoster/repropath/surgicalpath/female/cat/F%20fel%20anomaly%20mesonephric%20remnants%20YB108065%2011wl.jpg mesonephric r., cat (uoguelph.ca)]		\| <!-- [http://www.uoguelph.ca/~rfoster/repropath/surgicalpath/female/cat/F%20fel%20anomaly%20mesonephric%20remnants%20YB108065%2011wl.jpg mesonephric r., cat (uoguelph.ca)] -->
	\|-		\|-
	\|[[Walthard cell rest]]		\|[[Walthard cell rest]]

Michael: Michael moved page Gynecologic pathology to An introduction to gynecologic pathology

2014-05-12T00:01:49Z

Michael moved page Gynecologic pathology to An introduction to gynecologic pathology

← Older revision

Revision as of 00:01, 12 May 2014

Michael: /* Luteinized follicular cyst */

2014-05-11T22:58:47Z

Luteinized follicular cyst

← Older revision		Revision as of 22:58, 11 May 2014
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	==Luteinized follicular cyst==		==Luteinized follicular cyst==
	~~===General===~~		{{Main\|Luteinized follicular cyst}}
	*Benign.

	~~===Microscopic===~~
	~~Features:<ref>URL: [http://www.med-ed.virginia.edu/courses/path/gyn/ovary2.cfm http://www.med-ed.virginia.edu/courses/path/gyn/ovary2.cfm]. Accessed on: 20 May 2010.</ref>~~
	*Stratified cuboidal/columnar epithelium-like cells with:
	**Small nuclei and small nucleoli.
	**Cytoplasm may be eosinophilic.
	**Sit on spindled cells (theca interna) that is luteinized.

	~~====Image====~~
	~~<gallery>~~
	~~Image:Luteinized_follicular_cyst.jpg~~ \| Luteinized follicular cyst~~. (WC/Nephron)~~
	~~</gallery>~~

	=Other=		=Other=

Michael: /* Walthard cell rest */ split out

2014-05-11T22:47:18Z

Walthard cell rest: split out

← Older revision		Revision as of 22:47, 11 May 2014
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	==Walthard cell rest==		==Walthard cell rest==
	~~===General===~~		*[[AKA]] ''Walthard cell nest''.
	*[[AKA]] ''Walthard cell ~~'''n'''est~~''.		{{Main\|Walthard cell rest}}
	*Benign.

	~~====Epidemiology====~~
	*Thought to be related to [[Brenner tumour]].

	~~===Microscopic===~~
	~~Features:<ref name=Ref_GP332>~~{{~~Ref_GP~~\|~~332}}</ref>~~
	*Collection of eosinophilic (i.e. pink) cuboidal cells; usually solid, may be cystic.
	*Elliptical nucleus with single groove along major axis; "coffee bean" nucleus -- '''key feature'''.

	~~Location:~~
	*Usually in soft tissue of the uterine tube.

	~~====Images====~~
	~~<gallery>~~
	~~Image:~~Walthard cell rest ~~- very high mag.jpg \| WCR - very high mag.~~
	~~Image:Walthard cell rest - high mag.jpg \| WCR - high mag.~~
	~~Image:Walthard cell rest - intermed mag.jpg \| WCR - intermed. mag.~~
	~~Image:Walthard cell rest - low mag.jpg \| WCR - low mag.~~
	~~Image:Walthard cell rest - very low mag.jpg \| WCR - very low mag.~~
	~~</gallery>~~

	==Paraurethral cyst==		==Paraurethral cyst==

Michael: /* Mesonephric duct remnant */

2014-04-19T01:11:14Z

Mesonephric duct remnant

← Older revision		Revision as of 01:11, 19 April 2014
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	==Mesonephric duct remnant==		==Mesonephric duct remnant==
	~~:''Gartner duct cyst'', ''mesonephric duct cyst'' and ''Wolffian duct cyst'' redirect here.~~
	*[[AKA]] ''Wolffian duct remnant''.		*[[AKA]] ''Wolffian duct remnant''.
	*[[AKA]] ''Gartner duct''.<ref>URL: [http://webpathology.com/image.asp?n=3&Case=540 http://webpathology.com/image.asp?n=3&Case=540]. Accessed on: 22 October 2012.</ref>		*[[AKA]] ''Gartner duct''.<ref>URL: [http://webpathology.com/image.asp?n=3&Case=540 http://webpathology.com/image.asp?n=3&Case=540]. Accessed on: 22 October 2012.</ref>

Michael: /* Mesonephric duct remnant */ split out

2014-04-19T01:08:12Z

Mesonephric duct remnant: split out

← Older revision		Revision as of 01:08, 19 April 2014
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	*[[AKA]] ''Wolffian duct remnant''.		*[[AKA]] ''Wolffian duct remnant''.
	*[[AKA]] ''Gartner duct''.<ref>URL: [http://webpathology.com/image.asp?n=3&Case=540 http://webpathology.com/image.asp?n=3&Case=540]. Accessed on: 22 October 2012.</ref>		*[[AKA]] ''Gartner duct''.<ref>URL: [http://webpathology.com/image.asp?n=3&Case=540 http://webpathology.com/image.asp?n=3&Case=540]. Accessed on: 22 October 2012.</ref>
			{{Main\|Mesonephric duct remnant}}
	~~===General===~~
	~~Epidemiology:~~
	*Embryological remnant - benign.
	**Wolffian duct = precursor of male reproductive tract.<ref name=pmid16567946>{{~~cite journal \|author=Hannema SE, Print CG, Charnock-Jones DS, Coleman N, Hughes IA \|title=Changes in gene expression during Wolffian duct development \|journal=Horm. Res. \|volume=65~~ \|~~issue=4 \|pages=200–9 \|year=2006 \|pmid=16567946 \|doi=10.1159/000092408 \|url=}}</ref>~~

	~~Notes:~~
	*This is ''not'' a finding that is reported. The importance of this finding is knowing it isn't something neoplastic.
	*Lame way of remember the synonyms ''Gartner, Mesonephric, and Wolffian'': ''GMW''... it is trying to be a ''BMW'' but in ''g''irls.

	~~===Gross===~~
	*Classically anterior-lateral wall of the [[vagina]].<ref name=Ref_GP97>{{Ref GP\|97}}</ref>

	~~Note:~~
	*Same location as Muellerian cyst.
	~~===Microscopic===~~
	~~Features:<ref>Sternberg SE. Histology for Pathologists. 2nd Ed. P.893.</ref>~~
	*Small duct -- typically ~50-100 micrometres in diameter.
	**Duct lined by cuboidal cells with moderate eosinophilic cytoplasm.

	~~DDx:~~
	*Muellerian cyst - most common vaginal cyst.<ref name=Ref_GP97>{{Ref GP\|97}}</ref>
	*[[Vaginal inclusion cyst]].
	*[[Cervical adenocarcinoma]], not otherwise specified.
	*[[Minimal deviation adenocarcinoma of the uterine cervix]].
	*[[Mesonephric adenocarcinoma]] - has cellular atypia.
	*[[Wolffian duct hyperplasia]].

	~~Images:~~
	*[http://www.webpathology.com/image.asp?case=550&n=1 Mesonephric duct remnant ~~- low mag. (webpathology.com)].~~
	*[http://www.webpathology.com/image.asp?n=2&Case=550 Mesonephric duct remnant - high mag. (webpathology.com)].

	~~===IHC===~~
	~~Features:<ref name=Ref_WMSP442>{{Ref WMSP\|442}}</ref>~~
	*CD10 +ve.
	*CK7 +ve.
	*PAX2 +ve (nuclear - strong & diffuse).<ref name=pmid20061933>{{Cite journal \| last1 = Rabban \| first1 = JT. \| last2 = McAlhany \| first2 = S. \| last3 = Lerwill \| first3 = MF. \| last4 = Grenert \| first4 = JP. \| last5 = Zaloudek \| first5 = CJ. \| title = PAX2 distinguishes benign mesonephric and mullerian glandular lesions of the cervix from endocervical adenocarcinoma, including minimal deviation adenocarcinoma. \| journal = Am J Surg Pathol \| volume = 34 \| issue = 2 \| pages = 137-46 \| month = Feb \| year = 2010 \| doi = 10.1097/PAS.0b013e3181c89c98 \| PMID = 20061933 }}~~</ref>~~
	**Cancers often lose staining.

	==Walthard cell rest==		==Walthard cell rest==

Michael: /* Mesonephric duct remnant */

2013-12-09T11:45:28Z

Mesonephric duct remnant

← Older revision		Revision as of 11:45, 9 December 2013
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	*Classically anterior-lateral wall of the [[vagina]].<ref name=Ref_GP97>{{Ref GP\|97}}</ref>		*Classically anterior-lateral wall of the [[vagina]].<ref name=Ref_GP97>{{Ref GP\|97}}</ref>

			Note:
			*Same location as Muellerian cyst.
	===Microscopic===		===Microscopic===
	Features:<ref>Sternberg SE. Histology for Pathologists. 2nd Ed. P.893.</ref>		Features:<ref>Sternberg SE. Histology for Pathologists. 2nd Ed. P.893.</ref>
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	DDx:		DDx:
	*Muellerian cyst - most common vaginal cyst.		*Muellerian cyst - most common vaginal cyst.<ref name=Ref_GP97>{{Ref GP\|97}}</ref>
	*[[Vaginal inclusion cyst]].		*[[Vaginal inclusion cyst]].
	*[[Cervical adenocarcinoma]], not otherwise specified.		*[[Cervical adenocarcinoma]], not otherwise specified.