Anemia - Revision history

Michael: /* Classifications */

2022-05-02T15:02:27Z

Classifications

2015-07-31T02:38:37Z

+image

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	'''Anemia''' is low hemoglobin.		[[Image:Iron_deficiency_anemia_blood_film.jpg\|thumb\|Blood film in iron deficiency anemia. (WC)]]
			'''Anemia''' is an abnormally low hemoglobin.

	There is a long list of causes for anemia. Usually, anemia is grouped by [[RBC]] cell size, mean corpuscular volume (MCV).		There is a long list of causes for anemia. Usually, anemia is grouped by [[RBC]] cell size, mean corpuscular volume (MCV).

2013-12-26T02:28:54Z

← Older revision		Revision as of 02:28, 26 December 2013
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	'''Anemia''' is low hemoglobin.		'''Anemia''' is low hemoglobin.

	There is a long list of causes for anemia. Usually, anemia is grouped by RBC cell size, mean corpuscular volume (MCV).		There is a long list of causes for anemia. Usually, anemia is grouped by [[RBC]] cell size, mean corpuscular volume (MCV).

	==Classifications==		==Classifications==

2013-12-26T02:03:46Z

+normocytic anemia

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	*[[Myelodysplastic syndromes]].		*[[Myelodysplastic syndromes]].
	*Liver disease ([[cirrhosis]]).		*Liver disease ([[cirrhosis]]).
	*Thyroid disease (hypothyroidism).		*Thyroid disease ([[hypothyroidism]]).
	*Post-splenectomy.		*Post-splenectomy.

			===Normocytic anemia===
			One DDx of normocytic anemia:<ref>{{Cite journal \| last1 = Brill \| first1 = JR. \| last2 = Baumgardner \| first2 = DJ. \| title = Normocytic anemia. \| journal = Am Fam Physician \| volume = 62 \| issue = 10 \| pages = 2255-64 \| month = Nov \| year = 2000 \| doi = \| PMID = 11126852 }}</ref>
			*Acute blood loss.
			*Hypersplenism.
			*Hemolytic disorders.
			**Congenital conditions.
			**Hemoglobinopathies, e.g. [[sickle cell disease]].

			A cute mnemonic ''ABBRA'':
			*Anemia of chronic disease.
			*Bone marrow infiltration.
			*Bone marrow failure.
			*[[Renal failure]].
			*Acute hemorrhage.

	=Specific types of anemia=		=Specific types of anemia=

2012-05-01T15:47:02Z

2012-04-21T18:53:56Z

Macrocytic anemia

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	*Vitamin B12 deficiency.		*Vitamin B12 deficiency.
	*Rx.		*Rx.
	*Myelodysplastic syndromes.		*[[Myelodysplastic syndromes]].
	*Liver disease ([[cirrhosis]]).		*Liver disease ([[cirrhosis]]).
	*Thyroid disease (hypothyroidism).		*Thyroid disease (hypothyroidism).

2012-04-20T20:35:36Z

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	=Specific types of anemia=		=Specific types of anemia=
	==Pernicious anemia==		==Pernicious anemia==
	~~===General===~~		{{Main\|Pernicious anemia}}
	*Macrocytic anemia.

	~~Etiology:~~		==Sickle cell anemia==
	*Autoimmune - leads to loss of parietal cells.		{{Main\|Sickle cell anemia}}
	**Parietal cells produce ''intrinsic factor'' (important for vitamin B12 absorption) and ''hydrogen chloride''.

	~~Diagnosis - serology for antibodies to:<ref name~~=~~pmid12643357>{{Cite journal \| last1~~ = ~~Oh \| first1~~ = ~~R. \| last2~~ = ~~Brown \| first2 = DL. \| title = Vitamin B12 deficiency. \| journal = Am Fam Physician \| volume = 67 \| issue = 5~~ \| ~~pages = 979-86 \| month = Mar \| year = 2003 \| doi = \| PMID = 12643357 }}</ref>~~
	*Parietal cells.
	*Iintrinsic factor.

	~~===Microscopic===~~
	~~Features:~~
	*Loss of parietal cells.

	~~=See also=~~
	*[[Sickle cell anemia~~]].~~

	=References=		=References=

2012-04-20T20:28:59Z

Pernicious anemia

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	Diagnosis - serology for antibodies to:<ref name=pmid12643357>{{Cite journal \| last1 = Oh \| first1 = R. \| last2 = Brown \| first2 = DL. \| title = Vitamin B12 deficiency. \| journal = Am Fam Physician \| volume = 67 \| issue = 5 \| pages = 979-86 \| month = Mar \| year = 2003 \| doi = \| PMID = 12643357 }}</ref>		Diagnosis - serology for antibodies to:<ref name=pmid12643357>{{Cite journal \| last1 = Oh \| first1 = R. \| last2 = Brown \| first2 = DL. \| title = Vitamin B12 deficiency. \| journal = Am Fam Physician \| volume = 67 \| issue = 5 \| pages = 979-86 \| month = Mar \| year = 2003 \| doi = \| PMID = 12643357 }}</ref>
	*Parietal ~~cell~~.		*Parietal cells.
	*Iintrinsic factor.		*Iintrinsic factor.

2012-04-20T20:28:43Z

+units

← Older revision		Revision as of 20:28, 20 April 2012
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	{{familytree \| \| \| \| \| \| \| \| \| A01 \| \| \| \| \| \| \| A01=Anemia}}		{{familytree \| \| \| \| \| \| \| \| \| A01 \| \| \| \| \| \| \| A01=Anemia}}
	{{familytree \| \| \| \|,\|-\|-\|-\|-\|-\|+\|-\|-\|-\|-\|-\|.\| \|}}		{{familytree \| \| \| \|,\|-\|-\|-\|-\|-\|+\|-\|-\|-\|-\|-\|.\| \|}}
	{{familytree \| \| \| B01 \| \| \| \| B02 \| \| \| \| B03 \| B01 = [[Macrocytic anemia]] (MCV>100) \| B02 = [[Normocytic anemia]] (MCV 80–100) \| B03 = [[Microcytic anemia]] (MCV<80)}}		{{familytree \| \| \| B01 \| \| \| \| B02 \| \| \| \| B03 \| B01 = [[Macrocytic anemia]] (MCV>100 fl) \| B02 = [[Normocytic anemia]] (MCV 80–100 fl) \| B03 = [[Microcytic anemia]] (MCV<80 fl)}}
	{{familytree/end}}		{{familytree/end}}

2012-04-20T20:28:24Z

Pernicious anemia

← Older revision		Revision as of 20:28, 20 April 2012
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	*Autoimmune - leads to loss of parietal cells.		*Autoimmune - leads to loss of parietal cells.
	**Parietal cells produce ''intrinsic factor'' (important for vitamin B12 absorption) and ''hydrogen chloride''.		**Parietal cells produce ''intrinsic factor'' (important for vitamin B12 absorption) and ''hydrogen chloride''.

			Diagnosis - serology for antibodies to:<ref name=pmid12643357>{{Cite journal \| last1 = Oh \| first1 = R. \| last2 = Brown \| first2 = DL. \| title = Vitamin B12 deficiency. \| journal = Am Fam Physician \| volume = 67 \| issue = 5 \| pages = 979-86 \| month = Mar \| year = 2003 \| doi = \| PMID = 12643357 }}</ref>
			*Parietal cell.
			*Iintrinsic factor.

	===Microscopic===		===Microscopic===
	Features:		Features:
	*Loss of parietal cells.		*Loss of parietal cells.

	=See also=		=See also=
	*[[Sickle cell anemia]].		*[[Sickle cell anemia]].