Angiomyofibroblastoma - Revision history

Michael: +images

2014-05-08T07:56:42Z

+images

← Older revision		Revision as of 07:56, 8 May 2014
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	{{ Infobox diagnosis		{{ Infobox diagnosis
	\| Name = {{PAGENAME}}		\| Name = {{PAGENAME}}
	\| Image =		\| Image = Angiomyofibroblastoma humpath 4.jpg
	\| Width =		\| Width =
	\| Caption =		\| Caption = Angiomyofibroblastoma. [[H&E stain]].
	\| Synonyms =		\| Synonyms =
	\| Micro = hypercellular zones and hypocellular edematous zones, small blood vessels (~20 micrometers) - no large blood vessels, [[myxoid stroma]], small stellate cell/spindle cells without significant nuclear atypia		\| Micro = hypercellular zones and hypocellular edematous zones, small blood vessels (~20 micrometers) - no large blood vessels, [[myxoid stroma]], small stellate cell/spindle cells without significant nuclear atypia
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	===Images===		===Images===
			<gallery>
			Image:Angiomyofibroblastoma humpath 1.jpg \| AMF - low mag.
			Image:Angiomyofibroblastoma humpath 2.jpg \| AMF - intermed. mag.
			Image:Angiomyofibroblastoma humpath 3.jpg \| AMF - high mag.
			Image:Angiomyofibroblastoma humpath 4.jpg \| AMF - very high mag.
			</gallery>
	www:		www:
	*[http://www.webpathology.com/image.asp?case=544&n=4 Angiomyofibroblastoma (webpathology.com)]		*[http://www.webpathology.com/image.asp?case=544&n=4 Angiomyofibroblastoma (webpathology.com)]

Michael at 07:36, 8 May 2014

2014-05-08T07:36:42Z

← Older revision		Revision as of 07:36, 8 May 2014
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	\| Tx =		\| Tx =
	}}		}}
	'''Angiomyofibroblastoma''' is rare uncommon [[soft tissue lesion]] of the [[vulva]].		'''Angiomyofibroblastoma''', abbreviated '''AMF''',<ref name=pmid15782077>{{cite journal \|author=Cao D, Srodon M, Montgomery EA, Kurman RJ \|title=Lipomatous variant of angiomyofibroblastoma: report of two cases and review of the literature \|journal=Int. J. Gynecol. Pathol. \|volume=24 \|issue=2 \|pages=196–200 \|year=2005 \|month=April \|pmid=15782077 \|doi= \|url=}}</ref> is rare uncommon [[soft tissue lesion]] of the [[vulva]].

	==General==		==General==

Michael: /* See also */

2014-02-17T01:37:16Z

Michael: /* IHC */

2014-02-17T00:11:17Z

IHC

← Older revision		Revision as of 00:11, 17 February 2014
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	==IHC==		==IHC==
			*Desmin +ve.<ref name=pmid24328028/>
			*Vimentin +ve.<ref name=pmid24328028/>
	*SMA +ve.		*SMA +ve.
	*S-100 -ve.		*S-100 -ve.

Michael: infobox

2014-02-17T00:09:16Z

infobox

← Older revision		Revision as of 00:09, 17 February 2014
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			{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image =
			\| Width =
			\| Caption =
			\| Synonyms =
			\| Micro = hypercellular zones and hypocellular edematous zones, small blood vessels (~20 micrometers) - no large blood vessels, [[myxoid stroma]], small stellate cell/spindle cells without significant nuclear atypia
			\| Subtypes =
			\| LMDDx = [[aggressive angiomyxoma]]
			\| Stains =
			\| IHC =
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross = well-circumscribed
			\| Grossing =
			\| Site = female pelvis ([[vulva]]), case reports of similar lesion in males
			\| Assdx =
			\| Syndromes =
			\| Clinicalhx = slow growing, usu. not painful
			\| Signs =
			\| Symptoms =
			\| Prevalence = very rare
			\| Bloodwork =
			\| Rads =
			\| Endoscopy =
			\| Prognosis =
			\| Other =
			\| ClinDDx = [[Bartholin cyst]], [[aggressive angiomyxoma]]
			\| Tx =
			}}
	'''Angiomyofibroblastoma''' is rare uncommon [[soft tissue lesion]] of the [[vulva]].		'''Angiomyofibroblastoma''' is rare uncommon [[soft tissue lesion]] of the [[vulva]].

Michael at 00:06, 17 February 2014

2014-02-17T00:06:09Z

← Older revision		Revision as of 00:06, 17 February 2014
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	*Uncommon.		*Uncommon.
	*Similar lesions reported in males.<ref name=pmid24396463>{{Cite journal \| last1 = Ding \| first1 = G. \| last2 = Yu \| first2 = Y. \| last3 = Jin \| first3 = M. \| last4 = Xu \| first4 = J. \| last5 = Zhang \| first5 = Z. \| title = Angiomyofibroblastoma-like tumor of the scrotum: A case report and literature review. \| journal = Oncol Lett \| volume = 7 \| issue = 2 \| pages = 435-438 \| month = Feb \| year = 2014 \| doi = 10.3892/ol.2013.1741 \| PMID = 24396463 }}</ref><ref>{{Cite journal \| last1 = Butt \| first1 = Z. \| last2 = Slatnik \| first2 = J. \| last3 = Estey \| first3 = EP. \| title = Robotic assisted laparoscopic excision of a pelvic angiomyofibroblastoma-like tumor. \| journal = Can J Urol \| volume = 20 \| issue = 6 \| pages = 7067-9 \| month = Dec \| year = 2013 \| doi = \| PMID = 24331351 }}</ref>		*Similar lesions reported in males.<ref name=pmid24396463>{{Cite journal \| last1 = Ding \| first1 = G. \| last2 = Yu \| first2 = Y. \| last3 = Jin \| first3 = M. \| last4 = Xu \| first4 = J. \| last5 = Zhang \| first5 = Z. \| title = Angiomyofibroblastoma-like tumor of the scrotum: A case report and literature review. \| journal = Oncol Lett \| volume = 7 \| issue = 2 \| pages = 435-438 \| month = Feb \| year = 2014 \| doi = 10.3892/ol.2013.1741 \| PMID = 24396463 }}</ref><ref>{{Cite journal \| last1 = Butt \| first1 = Z. \| last2 = Slatnik \| first2 = J. \| last3 = Estey \| first3 = EP. \| title = Robotic assisted laparoscopic excision of a pelvic angiomyofibroblastoma-like tumor. \| journal = Can J Urol \| volume = 20 \| issue = 6 \| pages = 7067-9 \| month = Dec \| year = 2013 \| doi = \| PMID = 24331351 }}</ref>

			Clinical:<ref name=pmid24328028/>
			*Slow growing.
			*Uncommonly recur.
			*Usually painless.

	Clinical DDx:		Clinical DDx:
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	==Gross==		==Gross==
	*[[Vulva\|Vulvar lesion]].		*[[Vulva\|Vulvar lesion]].
	*Well-circumscribed.<ref>{{Cite journal \| last1 = Seo \| first1 = JW. \| last2 = Lee \| first2 = KA. \| last3 = Yoon \| first3 = NR. \| last4 = Lee \| first4 = JW. \| last5 = Kim \| first5 = BG. \| last6 = Bae \| first6 = DS. \| title = Angiomyofibroblastoma of the vulva. \| journal = Obstet Gynecol Sci \| volume = 56 \| issue = 5 \| pages = 349-51 \| month = Sep \| year = 2013 \| doi = 10.5468/ogs.2013.56.5.349 \| PMID = 24328028 }}</ref>		*Well-circumscribed.<ref name=pmid24328028>{{Cite journal \| last1 = Seo \| first1 = JW. \| last2 = Lee \| first2 = KA. \| last3 = Yoon \| first3 = NR. \| last4 = Lee \| first4 = JW. \| last5 = Kim \| first5 = BG. \| last6 = Bae \| first6 = DS. \| title = Angiomyofibroblastoma of the vulva. \| journal = Obstet Gynecol Sci \| volume = 56 \| issue = 5 \| pages = 349-51 \| month = Sep \| year = 2013 \| doi = 10.5468/ogs.2013.56.5.349 \| PMID = 24328028 }}</ref>

	==Microscopic==		==Microscopic==

Michael: /* Gross */

2014-02-17T00:04:43Z

Gross

← Older revision		Revision as of 00:04, 17 February 2014
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	==Gross==		==Gross==
	*[[Vulva\|Vulvar lesion]].		*[[Vulva\|Vulvar lesion]].
			*Well-circumscribed.<ref>{{Cite journal \| last1 = Seo \| first1 = JW. \| last2 = Lee \| first2 = KA. \| last3 = Yoon \| first3 = NR. \| last4 = Lee \| first4 = JW. \| last5 = Kim \| first5 = BG. \| last6 = Bae \| first6 = DS. \| title = Angiomyofibroblastoma of the vulva. \| journal = Obstet Gynecol Sci \| volume = 56 \| issue = 5 \| pages = 349-51 \| month = Sep \| year = 2013 \| doi = 10.5468/ogs.2013.56.5.349 \| PMID = 24328028 }}</ref>

	==Microscopic==		==Microscopic==

Michael: /* Gross */

2014-02-17T00:03:00Z

Gross

← Older revision		Revision as of 00:03, 17 February 2014
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	==Gross==		==Gross==
	*[[Vulvar lesion]].		*[[Vulva\|Vulvar lesion]].

	==Microscopic==		==Microscopic==

Michael: split out

2014-02-17T00:02:11Z

split out

← Older revision		Revision as of 00:02, 17 February 2014
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	==General==		==General==
	*Uncommon.		*Uncommon.
			*Similar lesions reported in males.<ref name=pmid24396463>{{Cite journal \| last1 = Ding \| first1 = G. \| last2 = Yu \| first2 = Y. \| last3 = Jin \| first3 = M. \| last4 = Xu \| first4 = J. \| last5 = Zhang \| first5 = Z. \| title = Angiomyofibroblastoma-like tumor of the scrotum: A case report and literature review. \| journal = Oncol Lett \| volume = 7 \| issue = 2 \| pages = 435-438 \| month = Feb \| year = 2014 \| doi = 10.3892/ol.2013.1741 \| PMID = 24396463 }}</ref><ref>{{Cite journal \| last1 = Butt \| first1 = Z. \| last2 = Slatnik \| first2 = J. \| last3 = Estey \| first3 = EP. \| title = Robotic assisted laparoscopic excision of a pelvic angiomyofibroblastoma-like tumor. \| journal = Can J Urol \| volume = 20 \| issue = 6 \| pages = 7067-9 \| month = Dec \| year = 2013 \| doi = \| PMID = 24331351 }}</ref>

	Clinical DDx:		Clinical DDx:
	*[[Bartholin cyst]].		*[[Bartholin cyst]].

			==Gross==
			*[[Vulvar lesion]].

	==Microscopic==		==Microscopic==
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	*[http://www.webpathology.com/image.asp?case=544&n=4 Angiomyofibroblastoma (webpathology.com)]		*[http://www.webpathology.com/image.asp?case=544&n=4 Angiomyofibroblastoma (webpathology.com)]
	*[http://www.webpathology.com/image.asp?n=5&Case=544 Angiomyofibroblastoma - high mag. (webpathology.com)].		*[http://www.webpathology.com/image.asp?n=5&Case=544 Angiomyofibroblastoma - high mag. (webpathology.com)].
			*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881198/figure/f2-ol-07-02-0435/ Angiomyofibroblastoma-like tumour of scrotum (nih.gov)].<ref name=pmid24396463/>

			==IHC==
			*SMA +ve.
			*S-100 -ve.
			*Actin -ve.
			*CD34 -ve.

	==See also==		==See also==

Michael: spllit out

2014-02-16T23:53:44Z

spllit out

← Older revision		Revision as of 23:53, 16 February 2014
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	~~#redirect~~ [[~~Soft_tissue_lesions#~~Angiomyofibroblastoma]]		'''Angiomyofibroblastoma''' is rare uncommon [[soft tissue lesion]] of the [[vulva]].

			==General==
			*Uncommon.

			Clinical DDx:
			*[[Bartholin cyst]].

			==Microscopic==
			Features:<ref name=pmid1314521>{{Cite journal \| last1 = Fletcher \| first1 = CD. \| last2 = Tsang \| first2 = WY. \| last3 = Fisher \| first3 = C. \| last4 = Lee \| first4 = KC. \| last5 = Chan \| first5 = JK. \| title = Angiomyofibroblastoma of the vulva. A benign neoplasm distinct from aggressive angiomyxoma. \| journal = Am J Surg Pathol \| volume = 16 \| issue = 4 \| pages = 373-82 \| month = Apr \| year = 1992 \| doi = \| PMID = 1314521 }}</ref>
			*Hypercellular zones and hypocellular edematous zones.
			*Small blood vessels (~20 micrometers) - no large blood vessels - '''key feature'''.
			*[[Myxoid stroma]] - '''key feature'''.
			*Small stellate cell/spindle cells without significant nuclear atypia.

			DDx:
			*[[Aggressive angiomyxoma]] - less cellular, large blood vessels.

			===Images===
			www:
			*[http://www.webpathology.com/image.asp?case=544&n=4 Angiomyofibroblastoma (webpathology.com)]
			*[http://www.webpathology.com/image.asp?n=5&Case=544 Angiomyofibroblastoma - high mag. (webpathology.com)].

			==See also==
			*[[Soft tissue lesions]].

			==References==
			{{Reflist\|2}}

	[[Category:Diagnosis]]		[[Category:Diagnosis]]
			[[Category:Soft tissue lesions]]

← Older revision		Revision as of 01:37, 17 February 2014
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	==See also==		==See also==
	*[[Soft tissue lesions]].		*[[Soft tissue lesions]].
			*[[Vulva]].
			*[[Scrotum]].

	==References==		==References==