Atypical small acinar proliferation - Revision history

Michael: /* See also */

2022-10-12T03:28:11Z

Michael at 14:49, 4 August 2022

2022-08-04T14:49:40Z

← Older revision		Revision as of 14:49, 4 August 2022
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	\| LMDDx = [[prostate adenocarcinoma]], benign prostate		\| LMDDx = [[prostate adenocarcinoma]], benign prostate
	\| Stains =		\| Stains =
	\| IHC = AMACR +ve, CK34betaE12 -ve, p63 -ve, PSA +ve		\| IHC = AMACR +ve, [[CK34betaE12]] -ve, p63 -ve, PSA +ve
	\| EM =		\| EM =
	\| Molecular =		\| Molecular =

Michael: /* General */

2018-07-05T02:36:48Z

General

← Older revision		Revision as of 02:36, 5 July 2018
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	**One benchmark is < 3-5% of biopsies.<ref name=THvdK>THvdK. 19 June 2010.</ref>		**One benchmark is < 3-5% of biopsies.<ref name=THvdK>THvdK. 19 June 2010.</ref>
	*Never diagnosed on excision, i.e. prostatectomy specimen.		*Never diagnosed on excision, i.e. prostatectomy specimen.
	*Cancers diagnosed after ASAP are not more frequently clinically significant than cancers diagnosed after a diagnosis of benign or HGPIN.<ref name=pmid28888752>{{Cite journal \| last1 = Wiener \| first1 = S. \| last2 = Haddock \| first2 = P. \| last3 = Cusano \| first3 = J. \| last4 = Staff \| first4 = I. \| last5 = McLaughlin \| first5 = T. \| last6 = Wagner \| first6 = J. \| title = Incidence of Clinically Significant Prostate Cancer After a Diagnosis of Atypical Small Acinar Proliferation, High-grade Prostatic Intraepithelial Neoplasia, or Benign Tissue. \| journal = Urology \| volume = 110 \| issue = \| pages = 161-165 \| month = Dec \| year = 2017 \| doi = 10.1016/j.urology.2017.08.040 \| PMID = 28888752 }}</ref>		*Cancers diagnosed in biopsies after ASAP are not more frequently clinically significant than cancers diagnosed after a diagnosis of benign or HGPIN.<ref name=pmid28888752>{{Cite journal \| last1 = Wiener \| first1 = S. \| last2 = Haddock \| first2 = P. \| last3 = Cusano \| first3 = J. \| last4 = Staff \| first4 = I. \| last5 = McLaughlin \| first5 = T. \| last6 = Wagner \| first6 = J. \| title = Incidence of Clinically Significant Prostate Cancer After a Diagnosis of Atypical Small Acinar Proliferation, High-grade Prostatic Intraepithelial Neoplasia, or Benign Tissue. \| journal = Urology \| volume = 110 \| issue = \| pages = 161-165 \| month = Dec \| year = 2017 \| doi = 10.1016/j.urology.2017.08.040 \| PMID = 28888752 }}</ref>

	===Association with adenocarcinoma===		===Association with adenocarcinoma===

Michael: /* General */

2018-07-05T02:36:21Z

General

← Older revision		Revision as of 02:36, 5 July 2018
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	**One benchmark is < 3-5% of biopsies.<ref name=THvdK>THvdK. 19 June 2010.</ref>		**One benchmark is < 3-5% of biopsies.<ref name=THvdK>THvdK. 19 June 2010.</ref>
	*Never diagnosed on excision, i.e. prostatectomy specimen.		*Never diagnosed on excision, i.e. prostatectomy specimen.
	*Cancers diagnosed after ASAP are not more frequently clinically significant, than cancers diagnosed after a diagnosis of benign or HGPIN.<ref name=pmid28888752>{{Cite journal \| last1 = Wiener \| first1 = S. \| last2 = Haddock \| first2 = P. \| last3 = Cusano \| first3 = J. \| last4 = Staff \| first4 = I. \| last5 = McLaughlin \| first5 = T. \| last6 = Wagner \| first6 = J. \| title = Incidence of Clinically Significant Prostate Cancer After a Diagnosis of Atypical Small Acinar Proliferation, High-grade Prostatic Intraepithelial Neoplasia, or Benign Tissue. \| journal = Urology \| volume = 110 \| issue = \| pages = 161-165 \| month = Dec \| year = 2017 \| doi = 10.1016/j.urology.2017.08.040 \| PMID = 28888752 }}</ref>		*Cancers diagnosed after ASAP are not more frequently clinically significant than cancers diagnosed after a diagnosis of benign or HGPIN.<ref name=pmid28888752>{{Cite journal \| last1 = Wiener \| first1 = S. \| last2 = Haddock \| first2 = P. \| last3 = Cusano \| first3 = J. \| last4 = Staff \| first4 = I. \| last5 = McLaughlin \| first5 = T. \| last6 = Wagner \| first6 = J. \| title = Incidence of Clinically Significant Prostate Cancer After a Diagnosis of Atypical Small Acinar Proliferation, High-grade Prostatic Intraepithelial Neoplasia, or Benign Tissue. \| journal = Urology \| volume = 110 \| issue = \| pages = 161-165 \| month = Dec \| year = 2017 \| doi = 10.1016/j.urology.2017.08.040 \| PMID = 28888752 }}</ref>

	===Association with adenocarcinoma===		===Association with adenocarcinoma===

Michael: /* General */

2018-07-05T02:36:01Z

General

← Older revision		Revision as of 02:36, 5 July 2018
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	**One benchmark is < 3-5% of biopsies.<ref name=THvdK>THvdK. 19 June 2010.</ref>		**One benchmark is < 3-5% of biopsies.<ref name=THvdK>THvdK. 19 June 2010.</ref>
	*Never diagnosed on excision, i.e. prostatectomy specimen.		*Never diagnosed on excision, i.e. prostatectomy specimen.
			*Cancers diagnosed after ASAP are not more frequently clinically significant, than cancers diagnosed after a diagnosis of benign or HGPIN.<ref name=pmid28888752>{{Cite journal \| last1 = Wiener \| first1 = S. \| last2 = Haddock \| first2 = P. \| last3 = Cusano \| first3 = J. \| last4 = Staff \| first4 = I. \| last5 = McLaughlin \| first5 = T. \| last6 = Wagner \| first6 = J. \| title = Incidence of Clinically Significant Prostate Cancer After a Diagnosis of Atypical Small Acinar Proliferation, High-grade Prostatic Intraepithelial Neoplasia, or Benign Tissue. \| journal = Urology \| volume = 110 \| issue = \| pages = 161-165 \| month = Dec \| year = 2017 \| doi = 10.1016/j.urology.2017.08.040 \| PMID = 28888752 }}</ref>

	===Association with adenocarcinoma===		===Association with adenocarcinoma===

Michael: /* Sign out */

2017-06-15T21:33:43Z

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← Older revision		Revision as of 21:33, 15 June 2017
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	==Sign out==		==Sign out==
	<pre>		<pre>
	K. ~~PROSTATE~~, ~~LEFT LATERAL INTERIOR, BIOPSY~~:		C. Prostate, Left Base:
	- ~~ATYPICAL SMALL ACINAR PROLIFERATION~~.		- Atypical prostatic glands, suspicious for microfocus of adenocarcinoma.
	</pre>		</pre>

			===Block letters===
	<pre>		<pre>
	C. ~~Prostate~~, ~~Left Base~~:		K. PROSTATE, LEFT LATERAL INTERIOR, BIOPSY:
	- ~~Atypical prostatic glands, suspicious for microfocus of adenocarcinoma~~.		- ATYPICAL SMALL ACINAR PROLIFERATION.
	</pre>		</pre>

Michael: /* Sign out */

2015-05-15T02:29:19Z

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← Older revision		Revision as of 02:29, 15 May 2015
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	K. PROSTATE, LEFT LATERAL INTERIOR, BIOPSY:		K. PROSTATE, LEFT LATERAL INTERIOR, BIOPSY:
	- ATYPICAL SMALL ACINAR PROLIFERATION.		- ATYPICAL SMALL ACINAR PROLIFERATION.
			</pre>

			<pre>
			C. Prostate, Left Base:
			- Atypical prostatic glands, suspicious for microfocus of adenocarcinoma.
	</pre>		</pre>

Michael: /* IHC */

2014-05-11T00:42:19Z

IHC

← Older revision		Revision as of 00:42, 11 May 2014
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	Note:		Note:
	*~~Generally~~ ''not'' contributory.		*Often ''not'' contributory.

			===Images===
			<gallery>
			Image: Atypical small acinar proliferation - AMACR-CK34betaE12 -- intermed mag.jpg \| ASAP - intermed. mag.
			Image: Atypical small acinar proliferation - AMACR-CK34betaE12 -- high mag.jpg \| ASAP - high mag.
			Image: Atypical small acinar proliferation - AMACR-CK34betaE12 -- very high mag.jpg \| ASAP - very high mag.
			Image: Atypical small acinar proliferation - AMACR-CK34betaE12 - alt -- very high mag.jpg \| ASAP - very high mag.
			</gallery>

	==Sign out==		==Sign out==

Michael: +images

2014-05-11T00:36:30Z

+images

← Older revision		Revision as of 00:36, 11 May 2014
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	**Adenosis of the prostate.		**Adenosis of the prostate.
	**Sclerosing adenosis of the prostate.		**Sclerosing adenosis of the prostate.

			===Images===
			<gallery>
			Image: Atypical small acinar proliferation -- low mag.jpg \| ASAP - low mag.
			Image: Atypical small acinar proliferation -- intermed mag.jpg \| ASAP - intermed. mag.
			Image: Atypical small acinar proliferation - alt -- intermed mag.jpg \| ASAP - intermed. mag.
			Image: Atypical small acinar proliferation -- high mag.jpg \| ASAP - high mag.
			Image: Atypical small acinar proliferation -- very high mag.jpg \| ASAP - very high mag.
			</gallery>

	==IHC==		==IHC==

Michael: +image

2014-05-11T00:33:22Z

+image

← Older revision		Revision as of 00:33, 11 May 2014
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	{{ Infobox diagnosis		{{ Infobox diagnosis
	\| Name = {{PAGENAME}}		\| Name = {{PAGENAME}}
	\| Image =		\| Image = Atypical small acinar proliferation - alt -- intermed mag.jpg
	\| Width =		\| Width =
	\| Caption =		\| Caption = Atypical small acinar proliferation - top-left of image. [[H&E stain]].
	\| Synonyms = suspicious for prostate carcinoma		\| Synonyms = suspicious for prostate carcinoma
	\| Micro = morphology of prostate carcinoma but less than 6 glands (major criteria for prostate carcinoma: abnormal architecture (increased gland density, usu. small circular glands, "infiltrative growth" pattern), basal cells lost, cytological abnormalities (nuclear enlargement, nucleoli); minor criteria for prostate carcinoma: nuclear hyperchromasia, wispy blue mucin, pink amorphous secretions, intraluminal crystalloid, amphophilic cytoplasm, adjacent HGPIN, mitoses)		\| Micro = morphology of prostate carcinoma but less than 6 glands (major criteria for prostate carcinoma: abnormal architecture (increased gland density, usu. small circular glands, "infiltrative growth" pattern), basal cells lost, cytological abnormalities (nuclear enlargement, nucleoli); minor criteria for prostate carcinoma: nuclear hyperchromasia, wispy blue mucin, pink amorphous secretions, intraluminal crystalloid, amphophilic cytoplasm, adjacent HGPIN, mitoses)

← Older revision		Revision as of 03:28, 12 October 2022
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	*[[Waffle diagnosis]].		*[[Waffle diagnosis]].
	*[[Prostate gland]].		*[[Prostate gland]].
			*[[Atypical intraductal proliferation]].

	==References==		==References==