Basal cell adenocarcinoma - Revision history

Michael: /* Images */ fix

2013-07-30T13:26:04Z

Images: fix

← Older revision		Revision as of 13:26, 30 July 2013
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	Image:Basal_cell_adenocarcinoma_-_parotid_gland_-_very_high_mag.jpg \| BCAC - very high mag. (WC/Nephron)		Image:Basal_cell_adenocarcinoma_-_parotid_gland_-_very_high_mag.jpg \| BCAC - very high mag. (WC/Nephron)
	Image:Basal_cell_adenocarcinoma_-_2_-_parotid_gland_-_high_mag.jpg \| BCAC - high mag. (WC/Nephron)		Image:Basal_cell_adenocarcinoma_-_2_-_parotid_gland_-_high_mag.jpg \| BCAC - high mag. (WC/Nephron)
	Image: Basal cell adenocarcinoma - 2 - parotid gland - very high mag.jpg \| BCAC - very high mag.		Image: Basal cell adenocarcinoma - 2 - parotid gland - very high mag.jpg \| BCAC - very high mag. (WC/Nephron)
	</gallery>		</gallery>
	www:		www:

Michael: more

2013-07-30T13:25:49Z

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	Image:Basal_cell_adenocarcinoma_-_parotid_gland_-_intermed_mag.jpg \| BCAC - intermed. mag. (WC/Nephron)		Image:Basal_cell_adenocarcinoma_-_parotid_gland_-_intermed_mag.jpg \| BCAC - intermed. mag. (WC/Nephron)
	Image:Basal_cell_adenocarcinoma_-_parotid_gland_-_high_mag.jpg \| BCAC - high mag. (WC/Nephron)		Image:Basal_cell_adenocarcinoma_-_parotid_gland_-_high_mag.jpg \| BCAC - high mag. (WC/Nephron)
			Image:Basal_cell_adenocarcinoma_-_parotid_gland_-_very_high_mag.jpg \| BCAC - very high mag. (WC/Nephron)
	Image:Basal_cell_adenocarcinoma_-_2_-_parotid_gland_-_high_mag.jpg \| BCAC - high mag. (WC/Nephron)		Image:Basal_cell_adenocarcinoma_-_2_-_parotid_gland_-_high_mag.jpg \| BCAC - high mag. (WC/Nephron)
			Image: Basal cell adenocarcinoma - 2 - parotid gland - very high mag.jpg \| BCAC - very high mag.
	</gallery>		</gallery>
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Michael: tweak

2013-07-30T13:24:20Z

tweak

← Older revision		Revision as of 13:24, 30 July 2013
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	It should ''not'' be confused with ''[[basal cell carcinoma]]'', a very common tumour of the skin.		It should ''not'' be confused with ''[[basal cell carcinoma]]'', a very common tumour of the skin.
	===General===		==General==
	*Very rare.		*Very rare.
	*Malignant.		*Malignant.
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	*May arise from a ''[[basal cell adenoma]]''.<ref name=pmid8952553/>		*May arise from a ''[[basal cell adenoma]]''.<ref name=pmid8952553/>

	===Gross===		==Gross==
	*Usually in the parotid gland ~90% of cases.<ref name=pmid8952553>{{Cite journal \| last1 = Muller \| first1 = S. \| last2 = Barnes \| first2 = L. \| title = Basal cell adenocarcinoma of the salivary glands. Report of seven cases and review of the literature. \| journal = Cancer \| volume = 78 \| issue = 12 \| pages = 2471-7 \| month = Dec \| year = 1996 \| doi = \| PMID = 8952553 }}</ref>		*Usually in the parotid gland ~90% of cases.<ref name=pmid8952553>{{Cite journal \| last1 = Muller \| first1 = S. \| last2 = Barnes \| first2 = L. \| title = Basal cell adenocarcinoma of the salivary glands. Report of seven cases and review of the literature. \| journal = Cancer \| volume = 78 \| issue = 12 \| pages = 2471-7 \| month = Dec \| year = 1996 \| doi = \| PMID = 8952553 }}</ref>

	===Microscopic===		==Microscopic==
	Features:		Features:
	#Lesion is '''not''' encapsulated - '''key feature'''.		#Lesion is '''not''' encapsulated - '''key feature'''.

Michael: tweak

2013-07-30T13:23:28Z

tweak

← Older revision		Revision as of 13:23, 30 July 2013
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	\| Micro = unencapsulated lesion with basal-like cells, tubular component - within basal component, dense hyaline stroma around tumour cells		\| Micro = unencapsulated lesion with basal-like cells, tubular component - within basal component, dense hyaline stroma around tumour cells
	\| Subtypes =		\| Subtypes =
	\| LMDDx = [[adenoid cystic carcinoma]], [[basal cell adenoma]]		\| LMDDx = [[adenoid cystic carcinoma]], [[basal cell adenoma]] - cannot be differentiated on [[cytology]]
	\| Stains =		\| Stains =
	\| IHC =		\| IHC =
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	\| Syndromes =		\| Syndromes =
	\| Clinicalhx =		\| Clinicalhx =
	\| Signs =		\| Signs = salivary gland mass
	\| Symptoms =		\| Symptoms =
	\| Prevalence =		\| Prevalence = very rare
	\| Bloodwork =		\| Bloodwork =
	\| Rads =		\| Rads =
	\| Endoscopy =		\| Endoscopy =
	\| Prognosis =		\| Prognosis = good
	\| Other =		\| Other =
	\| ClinDDx =		\| ClinDDx =

Michael: +infobox

2013-07-30T13:21:45Z

+infobox

← Older revision		Revision as of 13:21, 30 July 2013
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	#~~redirect~~ [[~~Salivary_glands~~#~~Basal_cell_adenocarcinoma~~]]		{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image = Basal_cell_adenocarcinoma_-_2_-_parotid_gland_-_high_mag.jpg
			\| Width =
			\| Caption = Basal cell adenocarcinoma. [[H&E stain]].
			\| Micro = unencapsulated lesion with basal-like cells, tubular component - within basal component, dense hyaline stroma around tumour cells
			\| Subtypes =
			\| LMDDx = [[adenoid cystic carcinoma]], [[basal cell adenoma]]
			\| Stains =
			\| IHC =
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross =
			\| Grossing =
			\| Site = [[salivary gland]] - usu. parotid gland
			\| Assdx =
			\| Syndromes =
			\| Clinicalhx =
			\| Signs =
			\| Symptoms =
			\| Prevalence =
			\| Bloodwork =
			\| Rads =
			\| Endoscopy =
			\| Prognosis =
			\| Other =
			\| ClinDDx =
			}}
			'''Basal cell adenocarcinoma''', abbreviated ''BCAC'', is an uncommon malignant [[salivary gland]] tumour.

			It should ''not'' be confused with ''[[basal cell carcinoma]]'', a very common tumour of the skin.
			===General===
			*Very rare.
			*Malignant.
			*Good prognosis.
			*May arise from a ''[[basal cell adenoma]]''.<ref name=pmid8952553/>

			===Gross===
			*Usually in the parotid gland ~90% of cases.<ref name=pmid8952553>{{Cite journal \| last1 = Muller \| first1 = S. \| last2 = Barnes \| first2 = L. \| title = Basal cell adenocarcinoma of the salivary glands. Report of seven cases and review of the literature. \| journal = Cancer \| volume = 78 \| issue = 12 \| pages = 2471-7 \| month = Dec \| year = 1996 \| doi = \| PMID = 8952553 }}</ref>

			===Microscopic===
			Features:
			#Lesion is '''not''' encapsulated - '''key feature'''.
			#Basal-like cells:
			#*Basophilic cells - '''key feature'''.
			#*Usually in nests.
			#**May be bilayered tubules ''or'' [[trabeculae]].
			#*Large basophilic nucleus.
			#*Minimal-to-moderate eosinophilic cytoplasm.
			#Stromal cells.
			#*Plump spindle cells without significant nuclear atypia.
			#**Stromal cell nuclei width ~= diameter [[RBC]].
			#*Dense hyaline stroma.
			#Tubular component.
			#*Within basal component, may be minimal.

			DDx:
			*[[Adenoid cystic carcinoma]].
			*[[Basal cell adenoma]] - encapsulated.
			*Basaloid [[squamous cell carcinoma]].

			===Images===
			<gallery>
			Image:Basal_cell_adenocarcinoma_-_parotid_gland_-_intermed_mag.jpg \| BCAC - intermed. mag. (WC/Nephron)
			Image:Basal_cell_adenocarcinoma_-_parotid_gland_-_high_mag.jpg \| BCAC - high mag. (WC/Nephron)
			Image:Basal_cell_adenocarcinoma_-_2_-_parotid_gland_-_high_mag.jpg \| BCAC - high mag. (WC/Nephron)
			</gallery>
			www:
			*[http://www.webpathology.com/image.asp?n=5&Case=115 Basal cell adenocarcinoma - intermed. mag. (webpathology.com)].
			*[http://www.webpathology.com/image.asp?n=6&Case=115 Basal cell adenocarcinoma - high mag. (webpathology.com)].

			==IHC==
			Features:<ref name=pmid17922602>{{Cite journal \| last1 = Farrell \| first1 = T. \| last2 = Chang \| first2 = YL. \| title = Basal cell adenocarcinoma of minor salivary glands. \| journal = Arch Pathol Lab Med \| volume = 131 \| issue = 10 \| pages = 1602-4 \| month = Oct \| year = 2007 \| doi = 10.1043/1543-2165(2007)131[1602:BCAOMS]2.0.CO;2 \| PMID = 17922602 }}</ref>
			*CK7 +ve (strong).
			*S100 +ve/-ve.

			==See also==
			*[[Salivary glands]].
			*[[Head and neck pathology]].

			==References==
			{{Reflist\|2}}

	[[Category:Diagnosis]]		[[Category:Diagnosis]]
			[[Category:Salivary gland]]
			[[Category:Head and neck pathology]]

Michael: create with cat.

2012-03-12T14:19:33Z

create with cat.

New page

#redirect [[Salivary_glands#Basal_cell_adenocarcinoma]]

[[Category:Diagnosis]]