Michael: /* Sign out */

2021-12-13T17:35:44Z

Sign out

← Older revision		Revision as of 17:35, 13 December 2021
Line 39:		Line 39:

	==Sign out==		==Sign out==
			<pre>
			Eyelid Lesion, Right Upper, Biopsy:
			- Lipogranulomas with active inflammation and lymphoplasmacytic infiltrate.
			- Reactive mucosa.

			Comment:
			The findings are consistent with a chalazion.
			</pre>

			===Block letters===
	<pre>		<pre>
	EYELID LESION, RIGHT UPPER, BIOPSY:		EYELID LESION, RIGHT UPPER, BIOPSY:

Michael: /* See also */

2015-10-01T13:58:08Z

Michael: split out

2015-10-01T13:56:54Z

split out

← Older revision		Revision as of 13:56, 1 October 2015
Line 1:		Line 1:
	~~#redirect~~ [[~~Eye#Chalazion~~]]		The '''chalazion''' is a common benign pathology of the [[eyelid]].

			==General==
			*Benign eye thingy that arises from the special sebaceous gland associated with the eyelid (Meibomian gland).
			*Usually diagnosed based on clinical appearance - accuracy ~94% in one series.<ref name=pmid14762403>{{Cite journal \| last1 = Ozdal \| first1 = PC. \| last2 = Codère \| first2 = F. \| last3 = Callejo \| first3 = S. \| last4 = Caissie \| first4 = AL. \| last5 = Burnier \| first5 = MN. \| title = Accuracy of the clinical diagnosis of chalazion. \| journal = Eye (Lond) \| volume = 18 \| issue = 2 \| pages = 135-8 \| month = Feb \| year = 2004 \| doi = 10.1038/sj.eye.6700603 \| PMID = 14762403 \| url = http://www.nature.com/eye/journal/v18/n2/full/6700603a.html }}</ref>

			==Gross==
			*Focal eyelid swelling - typically upper eyelid.

			DDx (clinical):<ref name=pmid14762403/>
			*[[Sebaceous cell carcinoma]].
			*[[Basal cell carcinoma]].

			===Images===
			<gallery>
			Image:Gradowka.jpg \| Chalazion (WC)
			</gallery>
			www:
			*[http://eyewiki.aao.org/File:Chalazion2_01242005.jpg Chalazion (eyewiki.aao.org)].

			==Microscopic==
			Features:
			*Lipogranulomas - '''key feature'''.<ref name=pmid14762403/>
			**[[Granuloma]]tous inflammation around clear spaces (lipid).<ref name=pmid15029054>{{Cite journal \| last1 = D'hermies \| first1 = F. \| last2 = Fayet \| first2 = B. \| last3 = Meyer \| first3 = A. \| last4 = Morel \| first4 = X. \| last5 = Halhal \| first5 = M. \| last6 = Elmaleh \| first6 = C. \| last7 = Azan \| first7 = F. \| last8 = Behar-Cohen \| first8 = F. \| last9 = Renard \| first9 = G. \| title = [Chalazion mimicking an eyelid tumor]. \| journal = J Fr Ophtalmol \| volume = 27 \| issue = 2 \| pages = 202-5 \| month = Feb \| year = 2004 \| doi = \| PMID = 15029054 }}</ref>
			**Multinucleated giant cells - common.
			***+/-[[Touton giant cell]]s.<ref>URL: [http://emedicine.medscape.com/article/1212709-workup http://emedicine.medscape.com/article/1212709-workup]. Accessed on: 9 February 2012.</ref>
			*Plasma cells - abundant - '''important'''.

			DDx:<ref>{{Ref DCHH\|194}}</ref>
			*[[Juvenile xanthogranuloma]].

			===Images===
			<gallery>
			Image:Chalazion_of_the_Eyelid.jpg \| Chalazion. (WC/euthman)
			</gallery>
			www:
			*[http://www.nature.com/eye/journal/v18/n2/fig_tab/6700603f1.html#figure-title Chalazion and its clinical DDx (nature.com)].<ref name=pmid14762403/>
			*[http://www.surgicalpathologyatlas.com/glfusion/mediagallery/media.php?f=0&sort=0&s=20080802170139555 Chalazion (surgicalpathologyatlas.com)].

			==Sign out==
			<pre>
			EYELID LESION, RIGHT UPPER, BIOPSY:
			- LIPOGRANULOMAS.
			- LYMPHOPLASMACYTIC RICH INFLAMMATORY INFILTRATE.
			- GRANULATION TISSUE.
			- REACTIVE SQUAMOUS MUCOSA.

			COMMENT:
			The findings are consistent with a chalazion.

			Special stains (ZN, PASD, GMS) did not demonstrate microorganisms.
			</pre>

			===Alternate===
			<pre>
			SKIN LESION, LEFT LOWER EYELID, PUNCH BIOPSY:
			- LIPOGRANULOMAS WITH GIANT CELLS AND A LYMPHOPLASMACYTIC RICH INFLAMMATORY
			INFILTRATE -- CONSISTENT WITH CHALAZION.
			- GRANULATION TISSUE.
			- NEGATIVE FOR MALIGNANCY.
			</pre>

			===Micro===
			The sections show a reactive squamous mucosa with palisading granulomas that surround clear spaces (lipid). This is accompanied by a lymphoplasmacytic rich inflammatory infiltrate. Granulation tissue is present. Rare multinucleated giant cells are identified. Neutrophils are numerous and seen in association with the histiocytes.

			No significant nuclear atypia is apparent.

			==See also==
			*[[Eye]].

			==References==
			{{Reflist\|1}}

			[[Category:Eye]]
	[[Category:Diagnosis]]		[[Category:Diagnosis]]

Michael: redirect

2012-01-24T19:40:58Z

redirect

New page

#redirect [[Eye#Chalazion]]

[[Category:Diagnosis]]

← Older revision		Revision as of 13:58, 1 October 2015
Line 68:		Line 68:
	==See also==		==See also==
	*[[Eye]].		*[[Eye]].
			*[[Eyelid]].

	==References==		==References==

Chalazion - Revision history

Michael: /* Sign out */

Michael: /* See also */

Michael: split out

Michael: redirect