Chiari malformation - Revision history

Jensflorian: histology in chiari (mostly type II)

2015-09-16T09:12:02Z

histology in chiari (mostly type II)

← Older revision		Revision as of 09:12, 16 September 2015
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	*Chiari type I - tonsils herniated<ref>URL: [http://rarediseases.info.nih.gov/GARD/Disease.aspx?diseaseID=9230 http://rarediseases.info.nih.gov/GARD/Disease.aspx?diseaseID=9230]. Accessed on: 6 May 2011.</ref> (radiologic definition: 4-6 mm below the plane of the foramen magnum).		*Chiari type I - tonsils herniated<ref>URL: [http://rarediseases.info.nih.gov/GARD/Disease.aspx?diseaseID=9230 http://rarediseases.info.nih.gov/GARD/Disease.aspx?diseaseID=9230]. Accessed on: 6 May 2011.</ref> (radiologic definition: 4-6 mm below the plane of the foramen magnum).
	**Associated with: sudden death,<ref>{{Cite journal \| last1 = Zhang \| first1 = J. \| last2 = Shao \| first2 = Y. \| last3 = Qin \| first3 = Z. \| last4 = Liu \| first4 = N. \| last5 = Zou \| first5 = D. \| last6 = Huang \| first6 = P. \| last7 = Chen \| first7 = Y. \| title = Sudden Unexpected Death due to Chiari Type I Malformation in a Road Accident Case. \| journal = J Forensic Sci \| volume = \| issue = \| pages = \| month = Dec \| year = 2012 \| doi = 10.1111/1556-4029.12051 \| PMID = 23278920 }}</ref> sleep apnea, cerebellar ataxia.		**Associated with: sudden death,<ref>{{Cite journal \| last1 = Zhang \| first1 = J. \| last2 = Shao \| first2 = Y. \| last3 = Qin \| first3 = Z. \| last4 = Liu \| first4 = N. \| last5 = Zou \| first5 = D. \| last6 = Huang \| first6 = P. \| last7 = Chen \| first7 = Y. \| title = Sudden Unexpected Death due to Chiari Type I Malformation in a Road Accident Case. \| journal = J Forensic Sci \| volume = \| issue = \| pages = \| month = Dec \| year = 2012 \| doi = 10.1111/1556-4029.12051 \| PMID = 23278920 }}</ref> sleep apnea, cerebellar ataxia.
	*Chiari type II - often assoc. with hydrocephaly at birth.		*Chiari type II - often assoc. with hydrocephaly at birth. Often associated with [[myelomeningocele]].
	*Chiari type III - cerebellum + brain stem herniate through foramen magnum +/- encephalocele.<ref>URL: [http://www.ninds.nih.gov/disorders/chiari/detail_chiari.htm http://www.ninds.nih.gov/disorders/chiari/detail_chiari.htm]. Accessed on: 6 May 2011.</ref>		*Chiari type III - cerebellum + brain stem herniate through foramen magnum +/- encephalocele.<ref>URL: [http://www.ninds.nih.gov/disorders/chiari/detail_chiari.htm http://www.ninds.nih.gov/disorders/chiari/detail_chiari.htm]. Accessed on: 6 May 2011.</ref>
	*Chiari type IV - cerebellar hypoplasia or no cerebellum.		*Chiari type IV - cerebellar hypoplasia or no cerebellum.

			==Histology==
			Surgery depends on clinical symptoms due to CSF obstructions. Specimens may include: <ref>{{Cite journal \| last1 = Piatt \| first1 = JH. \| last2 = D'Agostino \| first2 = A. \| title = The Chiari II malformation: lesions discovered within the fourth ventricle. \| journal = Pediatr Neurosurg \| volume = 30 \| issue = 2 \| pages = 79-85 \| month = Feb \| year = 1999 \| doi = 28767 \| PMID = 10325563 }}</ref>
			* Vertebral bone (decompression)
			* Hermiated cerebellar tonsils.
			* Reactive / dysplastic [[choroid plexus]].
			* Glial nodules.
			* Arachnoidal cysts.
			* [[Subependymoma]]s.
			In cases with [[myelomeningocele]] at autopsy, the posterior fossa should be examined.

			==Images==
			<gallery>
			File:Chiari2.jpg\|Schematic display of Chiari type II malformation.
			File:Chiari-Malformation_MRT_T2_sag.jpg \| Radiology of Chiari type II.
			File:Hypertrophic_plexus_chiari_II_low_mag.jpg \| Hypertrophic plexus choroideus in Chiari type II (low mag).
			File:Hypertrophic_plexus_chiari_II_intermed_mag.jpg \| Fibrous tissue within a hypertrophic plexus choroideus in Chiari type II (intermed mag).
			</gallery>

	==See also==		==See also==

Michael at 21:12, 2 January 2014

2014-01-02T21:12:44Z

← Older revision		Revision as of 21:12, 2 January 2014
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	{{Reflist\|2}}		{{Reflist\|2}}

			[[Category:Diagnosis]]
	[[Category:Neuropathology]]		[[Category:Neuropathology]]

Michael at 21:12, 2 January 2014

2014-01-02T21:12:21Z

← Older revision		Revision as of 21:12, 2 January 2014
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	*Usually a radiologic diagnosis.		*Usually a radiologic diagnosis.
	*May be seen in a [[fetal autopsy]].		*May be seen in a [[fetal autopsy]].

			Clinical:<ref>{{Cite journal \| last1 = Ferré Masó \| first1 = A. \| last2 = Poca \| first2 = MA. \| last3 = de la Calzada \| first3 = MD. \| last4 = Solana \| first4 = E. \| last5 = Romero Tomás \| first5 = O. \| last6 = Sahuquillo \| first6 = J. \| title = Sleep disturbance: a forgotten syndrome in patients with Chiari I malformation. \| journal = Neurologia \| volume = \| issue = \| pages = \| month = Mar \| year = 2011 \| doi = 10.1016/j.nrl.2011.01.008 \| PMID = 21420201 }}</ref>
			*Headaches, occipital.
			*Dizziness.
			*Nocturnal respiratory abnormalities.

	===Classification===		===Classification===
	Numbered from least severe to most severe:		Numbered from least severe to most severe:
	*Chiari type I - tonsils herniated<ref>URL: [http://rarediseases.info.nih.gov/GARD/Disease.aspx?diseaseID=9230 http://rarediseases.info.nih.gov/GARD/Disease.aspx?diseaseID=9230]. Accessed on: 6 May 2011.</ref> (radiologic definition: 4-6 mm below the plane of the foramen magnum).		*Chiari type I - tonsils herniated<ref>URL: [http://rarediseases.info.nih.gov/GARD/Disease.aspx?diseaseID=9230 http://rarediseases.info.nih.gov/GARD/Disease.aspx?diseaseID=9230]. Accessed on: 6 May 2011.</ref> (radiologic definition: 4-6 mm below the plane of the foramen magnum).
	**Associated with: sudden death, sleep apnea, cerebellar ataxia.		**Associated with: sudden death,<ref>{{Cite journal \| last1 = Zhang \| first1 = J. \| last2 = Shao \| first2 = Y. \| last3 = Qin \| first3 = Z. \| last4 = Liu \| first4 = N. \| last5 = Zou \| first5 = D. \| last6 = Huang \| first6 = P. \| last7 = Chen \| first7 = Y. \| title = Sudden Unexpected Death due to Chiari Type I Malformation in a Road Accident Case. \| journal = J Forensic Sci \| volume = \| issue = \| pages = \| month = Dec \| year = 2012 \| doi = 10.1111/1556-4029.12051 \| PMID = 23278920 }}</ref> sleep apnea, cerebellar ataxia.
	*Chiari type II - often assoc. with hydrocephaly at birth.		*Chiari type II - often assoc. with hydrocephaly at birth.
	*Chiari type III - cerebellum + brain stem herniate through foramen magnum +/- encephalocele.<ref>URL: [http://www.ninds.nih.gov/disorders/chiari/detail_chiari.htm http://www.ninds.nih.gov/disorders/chiari/detail_chiari.htm]. Accessed on: 6 May 2011.</ref>		*Chiari type III - cerebellum + brain stem herniate through foramen magnum +/- encephalocele.<ref>URL: [http://www.ninds.nih.gov/disorders/chiari/detail_chiari.htm http://www.ninds.nih.gov/disorders/chiari/detail_chiari.htm]. Accessed on: 6 May 2011.</ref>

Michael at 21:08, 2 January 2014

2014-01-02T21:08:52Z

← Older revision		Revision as of 21:08, 2 January 2014
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	'''Chiari malformation''' is a developmental abnormality of the brain.		'''Chiari malformation''' is a developmental abnormality of the brain.

	==Classification==		==General==
			*Usually a radiologic diagnosis.
			*May be seen in a [[fetal autopsy]].

			===Classification===
	Numbered from least severe to most severe:		Numbered from least severe to most severe:
	*Chiari type I - tonsils herniated<ref>URL: [http://rarediseases.info.nih.gov/GARD/Disease.aspx?diseaseID=9230 http://rarediseases.info.nih.gov/GARD/Disease.aspx?diseaseID=9230]. Accessed on: 6 May 2011.</ref> (radiologic definition: 4-6 mm below the plane of the foramen magnum).		*Chiari type I - tonsils herniated<ref>URL: [http://rarediseases.info.nih.gov/GARD/Disease.aspx?diseaseID=9230 http://rarediseases.info.nih.gov/GARD/Disease.aspx?diseaseID=9230]. Accessed on: 6 May 2011.</ref> (radiologic definition: 4-6 mm below the plane of the foramen magnum).
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	*Chiari type III - cerebellum + brain stem herniate through foramen magnum +/- encephalocele.<ref>URL: [http://www.ninds.nih.gov/disorders/chiari/detail_chiari.htm http://www.ninds.nih.gov/disorders/chiari/detail_chiari.htm]. Accessed on: 6 May 2011.</ref>		*Chiari type III - cerebellum + brain stem herniate through foramen magnum +/- encephalocele.<ref>URL: [http://www.ninds.nih.gov/disorders/chiari/detail_chiari.htm http://www.ninds.nih.gov/disorders/chiari/detail_chiari.htm]. Accessed on: 6 May 2011.</ref>
	*Chiari type IV - cerebellar hypoplasia or no cerebellum.		*Chiari type IV - cerebellar hypoplasia or no cerebellum.

			==See also==
			*[[Fetal autopsy]].
			*[[Neuropathology]].

	==References==		==References==

Michael: create

2014-01-02T21:06:36Z

create

New page

'''Chiari malformation''' is a developmental abnormality of the brain.

==Classification==
Numbered from least severe to most severe:
*Chiari type I - tonsils herniated<ref>URL: [http://rarediseases.info.nih.gov/GARD/Disease.aspx?diseaseID=9230 http://rarediseases.info.nih.gov/GARD/Disease.aspx?diseaseID=9230]. Accessed on: 6 May 2011.</ref> (radiologic definition: 4-6 mm below the plane of the foramen magnum).
**Associated with: sudden death, sleep apnea, cerebellar ataxia.
*Chiari type II - often assoc. with hydrocephaly at birth.
*Chiari type III - cerebellum + brain stem herniate through foramen magnum +/- encephalocele.<ref>URL: [http://www.ninds.nih.gov/disorders/chiari/detail_chiari.htm http://www.ninds.nih.gov/disorders/chiari/detail_chiari.htm]. Accessed on: 6 May 2011.</ref>
*Chiari type IV - cerebellar hypoplasia or no cerebellum.

==References==
{{Reflist|2}}

[[Category:Neuropathology]]