Cholesterol embolism - Revision history

Michael: /* General */

2014-06-18T17:23:30Z

General

← Older revision		Revision as of 17:23, 18 June 2014
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	*Significant CEs are often iatrogenic.		*Significant CEs are often iatrogenic.
	**Known complication of coronary catherization (incidence ~ 1%).<ref name=pmid12875753>{{cite journal \|author=Fukumoto Y, Tsutsui H, Tsuchihashi M, Masumoto A, Takeshita A \|title=The incidence and risk factors of cholesterol embolization syndrome, a complication of cardiac catheterization: a prospective study \|journal=J. Am. Coll. Cardiol. \|volume=42 \|issue=2 \|pages=211–6 \|year=2003 \|month=July \|pmid=12875753 \|doi=10.1016/S0735-1097(03)00579-5 \| url=http://linkinghub.elsevier.com/retrieve/pii/S0735109703005795}}</ref>		**Known complication of coronary catherization (incidence ~ 1%).<ref name=pmid12875753>{{cite journal \|author=Fukumoto Y, Tsutsui H, Tsuchihashi M, Masumoto A, Takeshita A \|title=The incidence and risk factors of cholesterol embolization syndrome, a complication of cardiac catheterization: a prospective study \|journal=J. Am. Coll. Cardiol. \|volume=42 \|issue=2 \|pages=211–6 \|year=2003 \|month=July \|pmid=12875753 \|doi=10.1016/S0735-1097(03)00579-5 \| url=http://linkinghub.elsevier.com/retrieve/pii/S0735109703005795}}</ref>
	**May complicate any vascular surgery, CABG.		**May complicate any vascular surgery, [[CABG]].

	==Microscopic==		==Microscopic==

Michael at 22:09, 29 December 2013

2013-12-29T22:09:50Z

← Older revision		Revision as of 22:09, 29 December 2013
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	\| Assdx = [[atherosclerosis]]		\| Assdx = [[atherosclerosis]]
	\| Syndromes =		\| Syndromes =
	\| Clinicalhx = +/-cardiovascular disease, +/-risk factors for cardiovascular disease (age, [[hypertension]], hypercholesterolemia, [[diabetes mellitus\|diabetes]], [[smoking]])		\| Clinicalhx = +/-cardiovascular intervention, +/-cardiovascular disease, +/-risk factors for cardiovascular disease (age, [[hypertension]], hypercholesterolemia, [[diabetes mellitus\|diabetes]], [[smoking]])
	\| Signs =		\| Signs =
	\| Symptoms =		\| Symptoms =

Michael: +image

2013-12-29T21:19:42Z

+image

← Older revision		Revision as of 21:19, 29 December 2013
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	{{ Infobox diagnosis		{{ Infobox diagnosis
	\| Name = {{PAGENAME}}		\| Name = {{PAGENAME}}
	\| Image =		\| Image = Cholesterol embolus - high mag.jpg
	\| Width =		\| Width =
	\| Caption = Cholesterol embolism. [[H&E stain]].		\| Caption = Cholesterol embolism. [[H&E stain]].
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	Image:Cholesterol_embolus_-_intermed_mag.jpg \| Cholesterol embolus - intermed. mag. (WC)		Image:Cholesterol_embolus_-_intermed_mag.jpg \| Cholesterol embolus - intermed. mag. (WC)
	Image:Cholesterol_embolus_-_high_mag.jpg \| Cholesterol embolus - high mag. (WC)		Image:Cholesterol_embolus_-_high_mag.jpg \| Cholesterol embolus - high mag. (WC)
			Image: Cholesterol embolus - very high mag.jpg \| Cholesterol embolus - very high mag. (WC)
	</gallery>		</gallery>

Michael at 21:18, 29 December 2013

2013-12-29T21:18:32Z

← Older revision		Revision as of 21:18, 29 December 2013
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			{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image =
			\| Width =
			\| Caption = Cholesterol embolism. [[H&E stain]].
			\| Synonyms =
			\| Micro = intravascular cholesterol clefts (biconvex white spaces), +/-macrophages and giant cells, +/-eosinophils
			\| Subtypes =
			\| LMDDx =
			\| Stains =
			\| IHC =
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross =
			\| Grossing =
			\| Site = [[blood vessels]] - arteries
			\| Assdx = [[atherosclerosis]]
			\| Syndromes =
			\| Clinicalhx = +/-cardiovascular disease, +/-risk factors for cardiovascular disease (age, [[hypertension]], hypercholesterolemia, [[diabetes mellitus\|diabetes]], [[smoking]])
			\| Signs =
			\| Symptoms =
			\| Prevalence = not typically biopsied, common in eldery
			\| Bloodwork =
			\| Rads =
			\| Endoscopy =
			\| Prognosis = dependent on extent
			\| Other =
			\| ClinDDx = [[vasculitis]]
			\| Tx =
			}}
	'''Cholesterol embolism''', abbreviated '''CE''', is characterized by intravascular cholesterol.		'''Cholesterol embolism''', abbreviated '''CE''', is characterized by intravascular cholesterol.

Michael: /* References */

2013-12-29T21:12:02Z

References

← Older revision		Revision as of 21:12, 29 December 2013
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	[[Category:Diagnosis]]		[[Category:Diagnosis]]
	[[Category:~~Vascular disease~~]]		[[Category:Cardiovascular pathology]]

Michael: split out

2013-12-29T21:11:23Z

split out

← Older revision		Revision as of 21:11, 29 December 2013
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	#redirect [[~~Vascular_disease#Cholesterol_embolism~~]]		'''Cholesterol embolism''', abbreviated '''CE''', is characterized by intravascular cholesterol.

			'''Cholesterol embolus''' (plural '''cholesterol emboli''') and '''cholesterol embolization''' redirect here.

			==General==
			*Strong association with [[atherosclerosis]] - found in ~3% of individuals in an [[autopsy]] series of 267 older individuals (mean age ~65 years).<ref name=pmid19970827>{{cite journal \| author=Flory CM \| title=Arterial occlusions produced by emboli from eroded aortic atheromatous plaques \| journal=Am J Pathol \| year= 1945 \| volume=21 \| pages=549–565 \| pmid=19970827 \| issue=3 \| pmc=1934118}}</ref>
			*Significant CEs are often iatrogenic.
			**Known complication of coronary catherization (incidence ~ 1%).<ref name=pmid12875753>{{cite journal \|author=Fukumoto Y, Tsutsui H, Tsuchihashi M, Masumoto A, Takeshita A \|title=The incidence and risk factors of cholesterol embolization syndrome, a complication of cardiac catheterization: a prospective study \|journal=J. Am. Coll. Cardiol. \|volume=42 \|issue=2 \|pages=211–6 \|year=2003 \|month=July \|pmid=12875753 \|doi=10.1016/S0735-1097(03)00579-5 \| url=http://linkinghub.elsevier.com/retrieve/pii/S0735109703005795}}</ref>
			**May complicate any vascular surgery, CABG.

			==Microscopic==
			Features:<ref name=Ref_Sternberg5_1735-6>{{Ref Sternberg5\|1735-6}}</ref>
			*Intravascular cholesterol clefts (biconvex white spaces) - '''key feature'''.
			**Typically ~ 100-500 micrometers (long axis) x 50-100 micrometers (short axis). (?)
			*+/-Macrophages and giant cells.
			*+/-Eosinophils.

			Note:
			*May be associated with ischemic changes and [[necrosis]].
			*Usually in the context of severe atherosclerosis.

			Note (trivia):
			*Cholesterol crystals dissolve with routine processing (paraffin embedding); this is why one talks of "cholesterol clefts".

			===Images===
			<gallery>
			Image:Cholesterol_embolus_-_intermed_mag.jpg \| Cholesterol embolus - intermed. mag. (WC)
			Image:Cholesterol_embolus_-_high_mag.jpg \| Cholesterol embolus - high mag. (WC)
			</gallery>

			==See also==
			*[[Vascular disease]].
			*[[Atherosclerosis]].

			==References==
			{{Reflist\|2}}

	[[Category:Diagnosis]]		[[Category:Diagnosis]]
			[[Category:Vascular disease]]

Michael: redirect

2012-01-01T20:32:36Z

redirect

New page

#redirect [[Vascular_disease#Cholesterol_embolism]]

[[Category:Diagnosis]]