Choroid plexus carcinoma - Revision history

Michael at 06:20, 10 December 2014

2014-12-10T06:20:40Z

← Older revision		Revision as of 06:20, 10 December 2014
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	\| Caption = Choroid plexus carcinoma. [[H&E stain]].		\| Caption = Choroid plexus carcinoma. [[H&E stain]].
	\| Synonyms =		\| Synonyms =
	\| Micro =		\| Micro = choroid plexus epithelium with nuclear pleomorphism & high NC ratio, mitoses, necrosis, +/-brain invasion
	\| Subtypes =		\| Subtypes =
	\| LMDDx = [[choroid plexus papilloma]], atypical plexus papilloma, [[atypical teratoid/rhabdoid tumour]]		\| LMDDx = [[choroid plexus papilloma]], atypical plexus papilloma, [[atypical teratoid/rhabdoid tumour]]

Michael at 06:19, 10 December 2014

2014-12-10T06:19:55Z

← Older revision		Revision as of 06:19, 10 December 2014
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			{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image = choroidplexuscarcinoma.png
			\| Width =
			\| Caption = Choroid plexus carcinoma. [[H&E stain]].
			\| Synonyms =
			\| Micro =
			\| Subtypes =
			\| LMDDx = [[choroid plexus papilloma]], atypical plexus papilloma, [[atypical teratoid/rhabdoid tumour]]
			\| Stains =
			\| IHC = cytokeratins +ve, EMA -ve, INI1 +ve, Ki-67 high
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross =
			\| Grossing =
			\| Site = [[brain]] - intraventricular mass, classically posterior fossa
			\| Assdx =
			\| Syndromes =
			\| Clinicalhx = typically children
			\| Signs =
			\| Symptoms =
			\| Prevalence = uncommon
			\| Bloodwork =
			\| Rads =
			\| Endoscopy =
			\| Prognosis =
			\| Other =
			\| ClinDDx =
			\| Tx =
			}}
	'''Choroid plexus carcinoma''' is an uncommon [[neuropathology tumour]] and the malignant counter part of [[choroid plexus papilloma]].		'''Choroid plexus carcinoma''' is an uncommon [[neuropathology tumour]] and the malignant counter part of [[choroid plexus papilloma]].

Michael at 06:08, 10 December 2014

2014-12-10T06:08:49Z

← Older revision		Revision as of 06:08, 10 December 2014
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	~~#redirect~~ [[~~Neuropathology_tumours#Choroid_plexus_carcinoma~~]]		'''Choroid plexus carcinoma''' is an uncommon [[neuropathology tumour]] and the malignant counter part of [[choroid plexus papilloma]].

			==General==
			*Usually pediatric population.
			*Malignant counterpart of ''[[choroid plexus papilloma]]''.<ref name=pmid19679976>{{Cite journal \| last1 = Singh \| first1 = A. \| last2 = Vermani \| first2 = S. \| last3 = Shruti \| first3 = S. \| title = Choroid plexus carcinoma: report of two cases. \| journal = Indian J Pathol Microbiol \| volume = 52 \| issue = 3 \| pages = 405-7 \| month = \| year = \| doi = 10.4103/0377-4929.55009 \| PMID = 19679976 }}</ref>
			*Poor prognosis - WHO grade III.<ref name=pmid20644273>{{Cite journal \| last1 = Menon \| first1 = G. \| last2 = Nair \| first2 = SN. \| last3 = Baldawa \| first3 = SS. \| last4 = Rao \| first4 = RB. \| last5 = Krishnakumar \| first5 = KP. \| last6 = Gopalakrishnan \| first6 = CV. \| title = Choroid plexus tumors: an institutional series of 25 patients. \| journal = Neurol India \| volume = 58 \| issue = 3 \| pages = 429-35 \| month = \| year = \| doi = 10.4103/0028-3886.66455 \| PMID = 20644273 \|URL = http://www.neurologyindia.com/article.asp?issn=0028-3886;year=2010;volume=58;issue=3;spage=429;epage=435;aulast=Menon }}</ref>
			*Classically posterior fossa.
			*Intraventricular mass.

			==Microscopic==
			Features:<ref name=pmid19679976/>
			*Choroid plexus epithelium with [[nuclear pleomorphism]] & high [[NC ratio]].
			*Mitoses.
			*Necrosis.
			*+/-Brain invasion.

			DDx:
			*[[Choroid plexus papilloma]].
			*Atypical plexus papilloma - has features intermediate between ''choroid plexus papilloma'' and ''choroid plexus carcinoma''.<ref name=pmid20644273/>
			*[[Atypical teratoid/rhabdoid tumour]].

			===Images===
			<gallery>
			Image:Choroidplexuscarcinoma.png \| CPC. (WC/Martin Hasselblatt)
			</gallery>
			www:
			*[http://path.upmc.edu/cases/case198/micro.html Choroid plexus carcinoma - several images (upmc.edu)].

			==IHC==
			Features:<ref name=pmid20644273/>
			*Cytokeratins +ve.
			*EMA usu. -ve.
			*GFAP -ve (~20% +ve).
			*Ki-67 high.
			**Useful to diff. from benign counterpart.
			*INI1 +ve.

			==See also==
			*[[Neuropathology tumours]].

			==References==
			{{Reflist\|2}}

	[[Category:Diagnosis]]		[[Category:Diagnosis]]
			[[Category:Neuropathology tumours]]

Michael: create /w cat.

2012-01-02T20:02:17Z

create /w cat.

New page

#redirect [[Neuropathology_tumours#Choroid_plexus_carcinoma]]

[[Category:Diagnosis]]