Chronic granulomatous disease - Revision history

Michael: /* General */

2016-03-24T22:29:06Z

General

← Older revision		Revision as of 22:29, 24 March 2016
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	*Individual with the condition have an increased susceptibility to infections.		*Individual with the condition have an increased susceptibility to infections.
	*Usually presents in infancy or childhood.<ref name=pmid21624140>{{Cite journal \| last1 = Song \| first1 = E. \| last2 = Jaishankar \| first2 = GB. \| last3 = Saleh \| first3 = H. \| last4 = Jithpratuck \| first4 = W. \| last5 = Sahni \| first5 = R. \| last6 = Krishnaswamy \| first6 = G. \| title = Chronic granulomatous disease: a review of the infectious and inflammatory complications. \| journal = Clin Mol Allergy \| volume = 9 \| issue = 1 \| pages = 10 \| month = \| year = 2011 \| doi = 10.1186/1476-7961-9-10 \| PMID = 21624140 }}</ref>		*Usually presents in infancy or childhood.<ref name=pmid21624140>{{Cite journal \| last1 = Song \| first1 = E. \| last2 = Jaishankar \| first2 = GB. \| last3 = Saleh \| first3 = H. \| last4 = Jithpratuck \| first4 = W. \| last5 = Sahni \| first5 = R. \| last6 = Krishnaswamy \| first6 = G. \| title = Chronic granulomatous disease: a review of the infectious and inflammatory complications. \| journal = Clin Mol Allergy \| volume = 9 \| issue = 1 \| pages = 10 \| month = \| year = 2011 \| doi = 10.1186/1476-7961-9-10 \| PMID = 21624140 }}</ref>
			*Incidence estimated at 1/200,000-1/250,000.<ref name=pmid10844935>{{Cite journal \| last1 = Winkelstein \| first1 = JA. \| last2 = Marino \| first2 = MC. \| last3 = Johnston \| first3 = RB. \| last4 = Boyle \| first4 = J. \| last5 = Curnutte \| first5 = J. \| last6 = Gallin \| first6 = JI. \| last7 = Malech \| first7 = HL. \| last8 = Holland \| first8 = SM. \| last9 = Ochs \| first9 = H. \| title = Chronic granulomatous disease. Report on a national registry of 368 patients. \| journal = Medicine (Baltimore) \| volume = 79 \| issue = 3 \| pages = 155-69 \| month = May \| year = 2000 \| doi = \| PMID = 10844935 }}</ref>

	==Microscopic==		==Microscopic==

Michael at 22:27, 24 March 2016

2016-03-24T22:27:46Z

← Older revision		Revision as of 22:27, 24 March 2016
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	*Five different genetic defects have been identified that cause the disease.		*Five different genetic defects have been identified that cause the disease.
	*Individual with the condition have an increased susceptibility to infections.		*Individual with the condition have an increased susceptibility to infections.
			*Usually presents in infancy or childhood.<ref name=pmid21624140>{{Cite journal \| last1 = Song \| first1 = E. \| last2 = Jaishankar \| first2 = GB. \| last3 = Saleh \| first3 = H. \| last4 = Jithpratuck \| first4 = W. \| last5 = Sahni \| first5 = R. \| last6 = Krishnaswamy \| first6 = G. \| title = Chronic granulomatous disease: a review of the infectious and inflammatory complications. \| journal = Clin Mol Allergy \| volume = 9 \| issue = 1 \| pages = 10 \| month = \| year = 2011 \| doi = 10.1186/1476-7961-9-10 \| PMID = 21624140 }}</ref>

	==Microscopic==		==Microscopic==

Michael: fix ref

2013-03-07T04:18:06Z

fix ref

← Older revision		Revision as of 04:18, 7 March 2013
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	'''Chronic granulomatous disease''', abbreviated '''CGD''', is a specific diagnosis; it should ''not'' be understood as a granulomatous disease that is of a long duration.		'''Chronic granulomatous disease''', abbreviated '''CGD''', is a specific diagnosis; it should ''not'' be understood as a granulomatous disease that is of a long duration.

	CGD is disorder of ~~neutrophils~~<ref name=pmid19098859/> and typically leads to widespread [[granuloma]]s.<ref name=pmid21116026>{{cite journal \|author=Seger RA \|title=Chronic granulomatous disease: recent advances in pathophysiology and treatment \|journal=Neth J Med \|volume=68 \|issue=11 \|pages=334–40 \|year=2010 \|month=November \|pmid=21116026 \|doi= \|url=}}</ref>		CGD is disorder of [[neutrophil]]s,<ref name=pmid19098859/> and typically leads to widespread [[granuloma]]s.<ref name=pmid21116026>{{cite journal \|author=Seger RA \|title=Chronic granulomatous disease: recent advances in pathophysiology and treatment \|journal=Neth J Med \|volume=68 \|issue=11 \|pages=334–40 \|year=2010 \|month=November \|pmid=21116026 \|doi= \|url=}}</ref>

	==General==		==General==
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	DDx:		DDx:
	*[[Crohn's disease]] - essentially indistinguishable histomorphologically in the GI tract.{{Cite journal \| last1 = Marks \| first1 = DJ. \| last2 = Miyagi \| first2 = K. \| last3 = Rahman \| first3 = FZ. \| last4 = Novelli \| first4 = M. \| last5 = Bloom \| first5 = SL. \| last6 = Segal \| first6 = AW. \| title = Inflammatory bowel disease in CGD reproduces the clinicopathological features of Crohn's disease. \| journal = Am J Gastroenterol \| volume = 104 \| issue = 1 \| pages = 117-24 \| month = Jan \| year = 2009 \| doi = 10.1038/ajg.2008.72 \| PMID = 19098859 }}</ref>		*[[Crohn's disease]] - essentially indistinguishable histomorphologically in the GI tract.<ref name=pmid19098859>{{Cite journal \| last1 = Marks \| first1 = DJ. \| last2 = Miyagi \| first2 = K. \| last3 = Rahman \| first3 = FZ. \| last4 = Novelli \| first4 = M. \| last5 = Bloom \| first5 = SL. \| last6 = Segal \| first6 = AW. \| title = Inflammatory bowel disease in CGD reproduces the clinicopathological features of Crohn's disease. \| journal = Am J Gastroenterol \| volume = 104 \| issue = 1 \| pages = 117-24 \| month = Jan \| year = 2009 \| doi = 10.1038/ajg.2008.72 \| PMID = 19098859 }}</ref>

	==References==		==References==

Michael: more

2013-03-07T04:17:21Z

← Older revision		Revision as of 04:17, 7 March 2013
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	'''Chronic granulomatous disease''' is a (specific) diagnosis ~~(as well~~ as a ~~category)~~. It is disorder of ~~phagocytes~~ and leads to widespread [[granuloma]]s.<ref>{{cite journal \|author=Seger RA \|title=Chronic granulomatous disease: recent advances in pathophysiology and treatment \|journal=Neth J Med \|volume=68 \|issue=11 \|pages=334–40 \|year=2010 \|month=November \|pmid=21116026 \|doi= \|url=}}</ref>		'''Chronic granulomatous disease''', abbreviated '''CGD''', is a specific diagnosis; it should ''not'' be understood as a granulomatous disease that is of a long duration.

			CGD is disorder of neutrophils<ref name=pmid19098859/> and typically leads to widespread [[granuloma]]s.<ref name=pmid21116026>{{cite journal \|author=Seger RA \|title=Chronic granulomatous disease: recent advances in pathophysiology and treatment \|journal=Neth J Med \|volume=68 \|issue=11 \|pages=334–40 \|year=2010 \|month=November \|pmid=21116026 \|doi= \|url=}}</ref>

	==General==		==General==
	*Five different genetic defects have been identified that cause the disease.		*Five different genetic defects have been identified that cause the disease.
	*~~Increase~~ susceptibility to infections.		*Individual with the condition have an increased susceptibility to infections.

	==Microscopic==		==Microscopic==
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	DDx:		DDx:
	*[[Crohn's disease]] - essentially indistinguishable histomorphologically in the GI tract.~~<ref name=pmid19098859>~~{{Cite journal \| last1 = Marks \| first1 = DJ. \| last2 = Miyagi \| first2 = K. \| last3 = Rahman \| first3 = FZ. \| last4 = Novelli \| first4 = M. \| last5 = Bloom \| first5 = SL. \| last6 = Segal \| first6 = AW. \| title = Inflammatory bowel disease in CGD reproduces the clinicopathological features of Crohn's disease. \| journal = Am J Gastroenterol \| volume = 104 \| issue = 1 \| pages = 117-24 \| month = Jan \| year = 2009 \| doi = 10.1038/ajg.2008.72 \| PMID = 19098859 }}</ref>		*[[Crohn's disease]] - essentially indistinguishable histomorphologically in the GI tract.{{Cite journal \| last1 = Marks \| first1 = DJ. \| last2 = Miyagi \| first2 = K. \| last3 = Rahman \| first3 = FZ. \| last4 = Novelli \| first4 = M. \| last5 = Bloom \| first5 = SL. \| last6 = Segal \| first6 = AW. \| title = Inflammatory bowel disease in CGD reproduces the clinicopathological features of Crohn's disease. \| journal = Am J Gastroenterol \| volume = 104 \| issue = 1 \| pages = 117-24 \| month = Jan \| year = 2009 \| doi = 10.1038/ajg.2008.72 \| PMID = 19098859 }}</ref>

	==References==		==References==

Michael: tweak

2013-03-07T04:13:14Z

tweak

← Older revision		Revision as of 04:13, 7 March 2013
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	DDx:		DDx:
	*[[Crohn's disease]].<ref name=pmid19098859>{{Cite journal \| last1 = Marks \| first1 = DJ. \| last2 = Miyagi \| first2 = K. \| last3 = Rahman \| first3 = FZ. \| last4 = Novelli \| first4 = M. \| last5 = Bloom \| first5 = SL. \| last6 = Segal \| first6 = AW. \| title = Inflammatory bowel disease in CGD reproduces the clinicopathological features of Crohn's disease. \| journal = Am J Gastroenterol \| volume = 104 \| issue = 1 \| pages = 117-24 \| month = Jan \| year = 2009 \| doi = 10.1038/ajg.2008.72 \| PMID = 19098859 }}</ref>		*[[Crohn's disease]] - essentially indistinguishable histomorphologically in the GI tract.<ref name=pmid19098859>{{Cite journal \| last1 = Marks \| first1 = DJ. \| last2 = Miyagi \| first2 = K. \| last3 = Rahman \| first3 = FZ. \| last4 = Novelli \| first4 = M. \| last5 = Bloom \| first5 = SL. \| last6 = Segal \| first6 = AW. \| title = Inflammatory bowel disease in CGD reproduces the clinicopathological features of Crohn's disease. \| journal = Am J Gastroenterol \| volume = 104 \| issue = 1 \| pages = 117-24 \| month = Jan \| year = 2009 \| doi = 10.1038/ajg.2008.72 \| PMID = 19098859 }}</ref>

	==References==		==References==

Michael: +ddx

2013-03-07T04:10:10Z

+ddx

← Older revision		Revision as of 04:10, 7 March 2013
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	Features:		Features:
	*[[Granulomas]] - see ''[[Basics]]''.		*[[Granulomas]] - see ''[[Basics]]''.

			DDx:
			*[[Crohn's disease]].<ref name=pmid19098859>{{Cite journal \| last1 = Marks \| first1 = DJ. \| last2 = Miyagi \| first2 = K. \| last3 = Rahman \| first3 = FZ. \| last4 = Novelli \| first4 = M. \| last5 = Bloom \| first5 = SL. \| last6 = Segal \| first6 = AW. \| title = Inflammatory bowel disease in CGD reproduces the clinicopathological features of Crohn's disease. \| journal = Am J Gastroenterol \| volume = 104 \| issue = 1 \| pages = 117-24 \| month = Jan \| year = 2009 \| doi = 10.1038/ajg.2008.72 \| PMID = 19098859 }}</ref>

	==References==		==References==
	{{Reflist\|1}}		{{Reflist\|2}}

	[[Category:Weird stuff]]		[[Category:Weird stuff]]

Michael: create

2011-03-02T20:34:38Z

create

← Older revision		Revision as of 20:34, 2 March 2011
Line 1:		Line 1:
	'''Chronic granulomatous disease''' is a (specific) diagnosis (as well as a category). It is disorder of phagocytes and leads to widespread [[granuloma]]s.<ref>{{cite journal \|author=Seger RA \|title=Chronic granulomatous disease: recent advances in pathophysiology and treatment \|journal=Neth J Med \|volume=68 \|issue=11 \|pages=334–40 \|year=2010 \|month=November \|pmid=21116026 \|doi= \|url=}}</ref>		'''Chronic granulomatous disease''' is a (specific) diagnosis (as well as a category). It is disorder of phagocytes and leads to widespread [[granuloma]]s.<ref>{{cite journal \|author=Seger RA \|title=Chronic granulomatous disease: recent advances in pathophysiology and treatment \|journal=Neth J Med \|volume=68 \|issue=11 \|pages=334–40 \|year=2010 \|month=November \|pmid=21116026 \|doi= \|url=}}</ref>

			==General==
			*Five different genetic defects have been identified that cause the disease.
			*Increase susceptibility to infections.

			==Microscopic==
			Features:
			*[[Granulomas]] - see ''[[Basics]]''.

	==References==		==References==

Michael: create

2011-03-02T20:29:44Z

create

New page

'''Chronic granulomatous disease''' is a (specific) diagnosis (as well as a category). It is disorder of phagocytes and leads to widespread [[granuloma]]s.<ref>{{cite journal |author=Seger RA |title=Chronic granulomatous disease: recent advances in pathophysiology and treatment |journal=Neth J Med |volume=68 |issue=11 |pages=334–40 |year=2010 |month=November |pmid=21116026 |doi= |url=}}</ref>

==References==
{{Reflist|1}}

[[Category:Weird stuff]]