Collagenous sprue - Revision history

Michael at 13:43, 26 December 2013

2013-12-26T13:43:44Z

← Older revision		Revision as of 13:43, 26 December 2013
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	\| Syndromes =		\| Syndromes =
	\| Clinicalhx = unresponsive to gluten free diet		\| Clinicalhx = unresponsive to gluten free diet
	\| Signs =		\| Signs = diarrhea
	\| Symptoms =		\| Symptoms =
	\| Prevalence = very rare		\| Prevalence = very rare

Michael at 13:42, 26 December 2013

2013-12-26T13:42:51Z

← Older revision		Revision as of 13:42, 26 December 2013
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	\| Caption =		\| Caption =
	\| Synonyms =		\| Synonyms =
	\| Micro = subepithelial collagen layer > 12 micrometres, villous atrophy, crypt atrophy.		\| Micro = subepithelial collagen layer > 12 micrometres, villous atrophy, crypt atrophy
	\| Subtypes =		\| Subtypes =
	\| LMDDx = [[celiac disease]]		\| LMDDx = [[celiac disease]]

Michael at 13:42, 26 December 2013

2013-12-26T13:42:35Z

← Older revision		Revision as of 13:42, 26 December 2013
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	\| Subtypes =		\| Subtypes =
	\| LMDDx = [[celiac disease]]		\| LMDDx = [[celiac disease]]
	\| Stains = demonstrate collagen - [[Masson trichrome]], [[Mallory trichrome]]		\| Stains = demonstrate collagen - [[Masson trichrome stain\|Masson trichrome]], [[Mallory trichrome stain\|Mallory trichrome]]
	\| IHC =		\| IHC =
	\| EM =		\| EM =
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	*[http://www.nature.com/modpathol/journal/v23/n1/fig_tab/modpathol2009151f2.html Collagenous sprue - several images (nature.com)].<ref name=pmid19855376>{{Cite journal \| last1 = Vakiani \| first1 = E. \| last2 = Arguelles-Grande \| first2 = C. \| last3 = Mansukhani \| first3 = MM. \| last4 = Lewis \| first4 = SK. \| last5 = Rotterdam \| first5 = H. \| last6 = Green \| first6 = PH. \| last7 = Bhagat \| first7 = G. \| title = Collagenous sprue is not always associated with dismal outcomes: a clinicopathological study of 19 patients. \| journal = Mod Pathol \| volume = 23 \| issue = 1 \| pages = 12-26 \| month = Jan \| year = 2010 \| doi = 10.1038/modpathol.2009.151 \| PMID = 19855376 }}</ref>		*[http://www.nature.com/modpathol/journal/v23/n1/fig_tab/modpathol2009151f2.html Collagenous sprue - several images (nature.com)].<ref name=pmid19855376>{{Cite journal \| last1 = Vakiani \| first1 = E. \| last2 = Arguelles-Grande \| first2 = C. \| last3 = Mansukhani \| first3 = MM. \| last4 = Lewis \| first4 = SK. \| last5 = Rotterdam \| first5 = H. \| last6 = Green \| first6 = PH. \| last7 = Bhagat \| first7 = G. \| title = Collagenous sprue is not always associated with dismal outcomes: a clinicopathological study of 19 patients. \| journal = Mod Pathol \| volume = 23 \| issue = 1 \| pages = 12-26 \| month = Jan \| year = 2010 \| doi = 10.1038/modpathol.2009.151 \| PMID = 19855376 }}</ref>
	*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886398/figure/F2/ Collagenous sprue (nih.gov)].<ref name=pmid20574500>{{Cite journal \| last1 = Xiao \| first1 = Z. \| last2 = Dasari \| first2 = VM. \| last3 = Kirby \| first3 = DF. \| last4 = Bronner \| first4 = M. \| last5 = Plesec \| first5 = TP. \| last6 = Lashner \| first6 = BA. \| title = Collagenous sprue: a case report and literature review. \| journal = Gastroenterol Hepatol (N Y) \| volume = 5 \| issue = 6 \| pages = 418-24 \| month = Jun \| year = 2009 \| doi = \| PMID = 20574500 }}</ref>		*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886398/figure/F2/ Collagenous sprue (nih.gov)].<ref name=pmid20574500>{{Cite journal \| last1 = Xiao \| first1 = Z. \| last2 = Dasari \| first2 = VM. \| last3 = Kirby \| first3 = DF. \| last4 = Bronner \| first4 = M. \| last5 = Plesec \| first5 = TP. \| last6 = Lashner \| first6 = BA. \| title = Collagenous sprue: a case report and literature review. \| journal = Gastroenterol Hepatol (N Y) \| volume = 5 \| issue = 6 \| pages = 418-24 \| month = Jun \| year = 2009 \| doi = \| PMID = 20574500 }}</ref>

			==Stains==
			Stains to demonstrate collagen:
			*[[Mallory trichrome stain\|Mallory trichrome]].
			*[[Masson trichrome stain\|Masson trichrome]].

	==See also==		==See also==

Michael at 13:41, 26 December 2013

2013-12-26T13:41:12Z

← Older revision		Revision as of 13:41, 26 December 2013
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			{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image =
			\| Width =
			\| Caption =
			\| Synonyms =
			\| Micro = subepithelial collagen layer > 12 micrometres, villous atrophy, crypt atrophy.
			\| Subtypes =
			\| LMDDx = [[celiac disease]]
			\| Stains = demonstrate collagen - [[Masson trichrome]], [[Mallory trichrome]]
			\| IHC =
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross =
			\| Grossing =
			\| Site = [[small bowel]]
			\| Assdx = possibly [[celiac disease]]
			\| Syndromes =
			\| Clinicalhx = unresponsive to gluten free diet
			\| Signs =
			\| Symptoms =
			\| Prevalence = very rare
			\| Bloodwork =
			\| Rads =
			\| Endoscopy =
			\| Prognosis =
			\| Other =
			\| ClinDDx =
			\| Tx =
			}}
	'''Collagenous sprue''' is a very rare disorder of the [[small bowel]]. There are approximately 60 reported cases in the world literature.<ref name=pmid21631278 >{{Cite journal \| last1 = Zhao \| first1 = X. \| last2 = Johnson \| first2 = RL. \| title = Collagenous sprue: a rare, severe small-bowel malabsorptive disorder. \| journal = Arch Pathol Lab Med \| volume = 135 \| issue = 6 \| pages = 803-9 \| month = Jun \| year = 2011 \| doi = 10.1043/2010-0028-RS.1 \| PMID = 21631278 }}</ref>		'''Collagenous sprue''' is a very rare disorder of the [[small bowel]]. There are approximately 60 reported cases in the world literature.<ref name=pmid21631278 >{{Cite journal \| last1 = Zhao \| first1 = X. \| last2 = Johnson \| first2 = RL. \| title = Collagenous sprue: a rare, severe small-bowel malabsorptive disorder. \| journal = Arch Pathol Lab Med \| volume = 135 \| issue = 6 \| pages = 803-9 \| month = Jun \| year = 2011 \| doi = 10.1043/2010-0028-RS.1 \| PMID = 21631278 }}</ref>

Michael at 01:54, 26 December 2013

2013-12-26T01:54:15Z

← Older revision		Revision as of 01:54, 26 December 2013
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	===Images===		===Images===
	*[http://www.nature.com/modpathol/journal/v23/n1/fig_tab/modpathol2009151f2.html Collagenous sprue (nature.com)].<ref name=pmid19855376>{{Cite journal \| last1 = Vakiani \| first1 = E. \| last2 = Arguelles-Grande \| first2 = C. \| last3 = Mansukhani \| first3 = MM. \| last4 = Lewis \| first4 = SK. \| last5 = Rotterdam \| first5 = H. \| last6 = Green \| first6 = PH. \| last7 = Bhagat \| first7 = G. \| title = Collagenous sprue is not always associated with dismal outcomes: a clinicopathological study of 19 patients. \| journal = Mod Pathol \| volume = 23 \| issue = 1 \| pages = 12-26 \| month = Jan \| year = 2010 \| doi = 10.1038/modpathol.2009.151 \| PMID = 19855376 }}</ref>		*[http://www.nature.com/modpathol/journal/v23/n1/fig_tab/modpathol2009151f2.html Collagenous sprue - several images (nature.com)].<ref name=pmid19855376>{{Cite journal \| last1 = Vakiani \| first1 = E. \| last2 = Arguelles-Grande \| first2 = C. \| last3 = Mansukhani \| first3 = MM. \| last4 = Lewis \| first4 = SK. \| last5 = Rotterdam \| first5 = H. \| last6 = Green \| first6 = PH. \| last7 = Bhagat \| first7 = G. \| title = Collagenous sprue is not always associated with dismal outcomes: a clinicopathological study of 19 patients. \| journal = Mod Pathol \| volume = 23 \| issue = 1 \| pages = 12-26 \| month = Jan \| year = 2010 \| doi = 10.1038/modpathol.2009.151 \| PMID = 19855376 }}</ref>
			*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886398/figure/F2/ Collagenous sprue (nih.gov)].<ref name=pmid20574500>{{Cite journal \| last1 = Xiao \| first1 = Z. \| last2 = Dasari \| first2 = VM. \| last3 = Kirby \| first3 = DF. \| last4 = Bronner \| first4 = M. \| last5 = Plesec \| first5 = TP. \| last6 = Lashner \| first6 = BA. \| title = Collagenous sprue: a case report and literature review. \| journal = Gastroenterol Hepatol (N Y) \| volume = 5 \| issue = 6 \| pages = 418-24 \| month = Jun \| year = 2009 \| doi = \| PMID = 20574500 }}</ref>

	==See also==		==See also==

Michael at 01:51, 26 December 2013

2013-12-26T01:51:26Z

← Older revision		Revision as of 01:51, 26 December 2013
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	DDx:		DDx:
	*[[Celiac sprue]].		*[[Celiac sprue]].

			===Images===
			*[http://www.nature.com/modpathol/journal/v23/n1/fig_tab/modpathol2009151f2.html Collagenous sprue (nature.com)].<ref name=pmid19855376>{{Cite journal \| last1 = Vakiani \| first1 = E. \| last2 = Arguelles-Grande \| first2 = C. \| last3 = Mansukhani \| first3 = MM. \| last4 = Lewis \| first4 = SK. \| last5 = Rotterdam \| first5 = H. \| last6 = Green \| first6 = PH. \| last7 = Bhagat \| first7 = G. \| title = Collagenous sprue is not always associated with dismal outcomes: a clinicopathological study of 19 patients. \| journal = Mod Pathol \| volume = 23 \| issue = 1 \| pages = 12-26 \| month = Jan \| year = 2010 \| doi = 10.1038/modpathol.2009.151 \| PMID = 19855376 }}</ref>

	==See also==		==See also==

Michael: tweak

2013-06-09T03:32:01Z

tweak

← Older revision		Revision as of 03:32, 9 June 2013
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	'''Collagenous sprue''' is a very rare disorder of the [[small bowel]] is approximately 60 reported cases.<ref name=pmid21631278 >{{Cite journal \| last1 = Zhao \| first1 = X. \| last2 = Johnson \| first2 = RL. \| title = Collagenous sprue: a rare, severe small-bowel malabsorptive disorder. \| journal = Arch Pathol Lab Med \| volume = 135 \| issue = 6 \| pages = 803-9 \| month = Jun \| year = 2011 \| doi = 10.1043/2010-0028-RS.1 \| PMID = 21631278 }}</ref>		'''Collagenous sprue''' is a very rare disorder of the [[small bowel]]. There are approximately 60 reported cases in the world literature.<ref name=pmid21631278 >{{Cite journal \| last1 = Zhao \| first1 = X. \| last2 = Johnson \| first2 = RL. \| title = Collagenous sprue: a rare, severe small-bowel malabsorptive disorder. \| journal = Arch Pathol Lab Med \| volume = 135 \| issue = 6 \| pages = 803-9 \| month = Jun \| year = 2011 \| doi = 10.1043/2010-0028-RS.1 \| PMID = 21631278 }}</ref>

	==General==		==General==

Michael: /* General */ more

2013-06-09T03:31:24Z

General: more

← Older revision		Revision as of 03:31, 9 June 2013
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	==General==		==General==
	*Thought to be related to [[celiac sprue]] - though somewhat controversial.<ref name=pmid21631278>{{Cite journal \| last1 = Zhao \| first1 = X. \| last2 = Johnson \| first2 = RL. \| title = Collagenous sprue: a rare, severe small-bowel malabsorptive disorder. \| journal = Arch Pathol Lab Med \| volume = 135 \| issue = 6 \| pages = 803-9 \| month = Jun \| year = 2011 \| doi = 10.1043/2010-0028-RS.1 \| PMID = 21631278 }}</ref><ref name=pmid23735026>{{Cite journal \| last1 = Busto-Bea \| first1 = V. \| last2 = Crespo-Pérez \| first2 = L. \| last3 = García-Miralles \| first3 = N. \| last4 = Ruiz-Del-Árbol-Olmos \| first4 = L. \| last5 = Cano-Ruiz \| first5 = A. \| title = Collagenous sprue: Don´t forget connective tissue in chronic diarrhea evaluation. \| journal = Rev Esp Enferm Dig \| volume = 105 \| issue = 3 \| pages = 171-174 \| month = May \| year = 2013 \| doi = \| PMID = 23735026 }}</ref>		*Thought to be related to [[celiac sprue]] - though somewhat controversial.<ref name=pmid21631278>{{Cite journal \| last1 = Zhao \| first1 = X. \| last2 = Johnson \| first2 = RL. \| title = Collagenous sprue: a rare, severe small-bowel malabsorptive disorder. \| journal = Arch Pathol Lab Med \| volume = 135 \| issue = 6 \| pages = 803-9 \| month = Jun \| year = 2011 \| doi = 10.1043/2010-0028-RS.1 \| PMID = 21631278 }}</ref><ref name=pmid23735026>{{Cite journal \| last1 = Busto-Bea \| first1 = V. \| last2 = Crespo-Pérez \| first2 = L. \| last3 = García-Miralles \| first3 = N. \| last4 = Ruiz-Del-Árbol-Olmos \| first4 = L. \| last5 = Cano-Ruiz \| first5 = A. \| title = Collagenous sprue: Don´t forget connective tissue in chronic diarrhea evaluation. \| journal = Rev Esp Enferm Dig \| volume = 105 \| issue = 3 \| pages = 171-174 \| month = May \| year = 2013 \| doi = \| PMID = 23735026 }}</ref>

			Clinical:
			*Diarrhea.
			**Not responsive to Gluten-free diet.

	==Microscopic==		==Microscopic==

Michael: /* See also */ +CC link

2013-06-09T03:30:27Z

Michael: /* Microscopic */

2013-06-09T03:30:10Z

Microscopic

← Older revision		Revision as of 03:30, 9 June 2013
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	==Microscopic==		==Microscopic==
	Features:<ref name=pmid21631278>{{Cite journal \| last1 = Zhao \| first1 = X. \| last2 = Johnson \| first2 = RL. \| title = Collagenous sprue: a rare, severe small-bowel malabsorptive disorder. \| journal = Arch Pathol Lab Med \| volume = 135 \| issue = 6 \| pages = 803-9 \| month = Jun \| year = 2011 \| doi = 10.1043/2010-0028-RS.1 \| PMID = 21631278 }}</ref>		Features:<ref name=pmid21631278>{{Cite journal \| last1 = Zhao \| first1 = X. \| last2 = Johnson \| first2 = RL. \| title = Collagenous sprue: a rare, severe small-bowel malabsorptive disorder. \| journal = Arch Pathol Lab Med \| volume = 135 \| issue = 6 \| pages = 803-9 \| month = Jun \| year = 2011 \| doi = 10.1043/2010-0028-RS.1 \| PMID = 21631278 }}</ref>
	*Subepithelial collagen layer > 12 micrometres.		*Subepithelial collagen layer > 12 micrometres - '''key feature'''.
	*Villous atrophy.		*Villous atrophy.
	*Crypt atrophy.		*Crypt atrophy.

← Older revision		Revision as of 03:30, 9 June 2013
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	==See also==		==See also==
	*[[Gastrointestinal pathology]].		*[[Gastrointestinal pathology]].
			*[[Collagenous colitis]].

	==References==		==References==