Cutaneous T-cell lymphoma - Revision history

Michael: /* See also */

2016-12-06T23:31:38Z

Michael at 22:21, 6 December 2016

2016-12-06T22:21:18Z

← Older revision		Revision as of 22:21, 6 December 2016
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	'''Cutaneous T-cell lymphoma''', abbreviated '''CTCL''', is a malignant [[dermatologic neoplasms\|neoplasm that arises in the skin]].		'''Cutaneous T-cell lymphoma''', abbreviated '''CTCL''', is a malignant lymphoid [[dermatologic neoplasms\|neoplasm that arises in the skin]].

	==General==		==General==

Michael: /* References */

2016-12-06T22:19:26Z

References

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	[[Category:Dermatopathology]]		[[Category:Dermatopathology]]
	[[Category:~~Hematopathology~~]]		[[Category:Haematopathology]]

Michael at 22:19, 6 December 2016

2016-12-06T22:19:11Z

← Older revision		Revision as of 22:19, 6 December 2016
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	'''~~Cutaneous_T~~-cell lymphoma''', abbreviated '''CTCL''', is a malignant [[dermatologic neoplasms\|neoplasm that arises in the skin]].		'''Cutaneous T-cell lymphoma''', abbreviated '''CTCL''', is a malignant [[dermatologic neoplasms\|neoplasm that arises in the skin]].

	==General==		==General==

Michael: split out

2016-12-06T22:19:02Z

split out

← Older revision		Revision as of 22:19, 6 December 2016
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	~~#redirect~~ [[~~Dermatologic_neoplasms#~~Cutaneous_T-~~cell_lymphoma~~]]		'''Cutaneous_T-cell lymphoma''', abbreviated '''CTCL''', is a malignant [[dermatologic neoplasms\|neoplasm that arises in the skin]].

			==General==
			*''Mycosis fungoides'' - is a subtype (???).
			*CTCL is more common than cutaneous B-cell lymphoma (CBCL).<ref>URL: [http://emedicine.medscape.com/article/1099540-overview http://emedicine.medscape.com/article/1099540-overview]. Accessed on: 24 August 2010.</ref><ref>URL: [http://emedicine.medscape.com/article/1098342-overview http://emedicine.medscape.com/article/1098342-overview]. Accessed on: 24 August 2010.</ref>

			Stages - like [[Kaposi sarcoma]]:
			*Patch.
			*Plaque.
			*Nodular.

			==Microscopic==
			*Atypical lymphocytes:
			**Have folded "cerebriform" nuclei; ''Sezary-Lutzner cells''.<ref name=Ref_Klatt385>{{Ref Klatt\|385}}</ref>
			*Grouping:
			**Nests in the epidermis - known as "Pautrier microabscesses".
			**Single lymphocytes in epidermis - without accompanying edema.
			**Short linear arrays of lymphocytes along the basal layer of the epidermis; "epidermotropism".<ref name=Ref_Klatt385>{{Ref Klatt\|385}}</ref>

			DDx:
			*[[Lymphomatoid papulosis]].

			===Images===
			<gallery>
			Image:Cutaneous_T-cell_lymphoma_-_very_high_mag.jpg \| CTCL - very high mag. (WC/Nephron)
			Image:Cutaneous_T-cell_lymphoma_-_intermed_mag.jpg \| CTCL - intermed. mag. (WC/Nephron)
			</gallery>
			www:
			*[http://www.jci.org/articles/view/24826/figure/2 CTCL (jci.org)].
			*[http://www.mdconsult.com/das/book/body/199872830-2/0/1709/I4-u1.0-B978-0-443-06694-8..50117-2--f2.fig CTCL (mdconsult.com)].

			==IHC==
			Key stain:
			*CD4 +ve.<ref>{{Ref PBoD8\|1185}}</ref>

			Other stains:
			*CD3 +ve.
			*CD8 -ve.
			*CD20 -ve (to r/o significant B cell population).
			*CD30 -ve.
			*CD5 +ve.
			*CD7 -ve (often lost first in T cell lymphomas).
			*Ki-67 high.
			*CD56 -ve.

			==See also==
			*[[Dermatologic neoplasms]]
			*[[Lymphoma]].

			==References==
			{{Reflist\|1}}

			[[Category:Dermatopathology]]
			[[Category:Hematopathology]]

Michael: chg redirect

2011-09-03T16:37:18Z

chg redirect

← Older revision		Revision as of 16:37, 3 September 2011
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	#redirect [[~~Dermatologic_cancer~~#Cutaneous_T-cell_lymphoma]]		#redirect [[Dermatologic_neoplasms#Cutaneous_T-cell_lymphoma]]

Michael: redirect for now

2011-09-01T20:24:38Z

redirect for now

New page

#redirect [[Dermatologic_cancer#Cutaneous_T-cell_lymphoma]]

← Older revision		Revision as of 23:31, 6 December 2016
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	*[[Dermatologic neoplasms]]		*[[Dermatologic neoplasms]]
	*[[Lymphoma]].		*[[Lymphoma]].
			*[[Cutaneous lymphoma]].

	==References==		==References==