Cytogenetic tests - Revision history

Michael: /* ISH */ w

2012-01-14T17:09:13Z

ISH: w

← Older revision		Revision as of 17:09, 14 January 2012
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	\|-		\|-
	\| BCR/ABL1		\| BCR/ABL1
	\| CML or ALL		\| [[CML]] or ALL
	\| Tx: [[imatinib]]		\| Tx: [[imatinib]]
	\|-		\|-

Michael: /* ISH */ w

2011-08-15T02:56:15Z

ISH: w

← Older revision		Revision as of 02:56, 15 August 2011
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	\| BCR/ABL1		\| BCR/ABL1
	\| CML or ALL		\| CML or ALL
	\| Tx (imatinib)		\| Tx: [[imatinib]]
	\|-		\|-
	\| MLL<ref>{{OMIM\|159555}}</ref>		\| MLL<ref>{{OMIM\|159555}}</ref>

Michael: wikify

2011-08-15T02:51:33Z

wikify

← Older revision		Revision as of 02:51, 15 August 2011
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	\| ERBB2 (HER2)		\| ERBB2 (HER2)
	\| [[breast cancer]]		\| [[breast cancer]]
	\| prognostic, Tx (trastuzumab)		\| prognostic, Tx ([[trastuzumab]])
	\|-		\|-
	\| EWSR1		\| EWSR1

Michael: /* ISH */ more

2011-05-12T20:32:41Z

ISH: more

← Older revision		Revision as of 20:32, 12 May 2011
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	\| BCL2		\| BCL2
	\| [[follicular lymphoma]]		\| [[follicular lymphoma]]
	\|		\| t(14;18)(q32;q21)<ref name=pmid21192062>{{Cite journal \| last1 = Yanai \| first1 = S. \| last2 = Nakamura \| first2 = S. \| last3 = Takeshita \| first3 = M. \| last4 = Fujita \| first4 = K. \| last5 = Hirahashi \| first5 = M. \| last6 = Kawasaki \| first6 = K. \| last7 = Kurahara \| first7 = K. \| last8 = Sakai \| first8 = Y. \| last9 = Matsumoto \| first9 = T. \| title = Translocation t(14;18)/IGH-BCL2 in gastrointestinal follicular lymphoma: correlation with clinicopathologic features in 48 patients. \| journal = Cancer \| volume = \| issue = \| pages = \| month = Dec \| year = 2010 \| doi = 10.1002/cncr.25811 \| PMID = 21192062 }}</ref>

	\|-		\|-
	\| ERBB2 (HER2)		\| ERBB2 (HER2)

Michael: wikify

2011-05-12T17:20:54Z

wikify

← Older revision		Revision as of 17:20, 12 May 2011
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	Findings:		Findings:
	*5q deletion seen in myelodysplastic syndromes.<ref>{{Cite journal \| last1 = Nimer \| first1 = SD. \| title = Clinical management of myelodysplastic syndromes with interstitial deletion of chromosome 5q. \| journal = J Clin Oncol \| volume = 24 \| issue = 16 \| pages = 2576-82 \| month = Jun \| year = 2006 \| doi = 10.1200/JCO.2005.03.6715 \| PMID = 16735711 }}		*5q deletion seen in [[myelodysplastic syndromes]].<ref>{{Cite journal \| last1 = Nimer \| first1 = SD. \| title = Clinical management of myelodysplastic syndromes with interstitial deletion of chromosome 5q. \| journal = J Clin Oncol \| volume = 24 \| issue = 16 \| pages = 2576-82 \| month = Jun \| year = 2006 \| doi = 10.1200/JCO.2005.03.6715 \| PMID = 16735711 }}
	</ref>		</ref>
	*Y deletion in [[MDS]]<ref name=pmid21269692>{{Cite journal \| last1 = Mallo \| first1 = M. \| last2 = Luño \| first2 = E. \| last3 = Sanzo \| first3 = C. \| last4 = Cervera \| first4 = J. \| last5 = Haase \| first5 = D. \| last6 = Schanz \| first6 = J. \| last7 = García-Manero \| first7 = G. \| last8 = Del Cañizo \| first8 = C. \| last9 = Sanz \| first9 = GF. \| title = Clinical impact of the clone size in MDS cases with monosomy 7 or 7q deletion, trisomy 8, 20q deletion and loss of Y chromosome. \| journal = Leuk Res \| volume = \| issue = \| pages = \| month = Jan \| year = 2011 \| doi = 10.1016/j.leukres.2011.01.003 \| PMID = 21269692 }}		*Y deletion in [[MDS]]<ref name=pmid21269692>{{Cite journal \| last1 = Mallo \| first1 = M. \| last2 = Luño \| first2 = E. \| last3 = Sanzo \| first3 = C. \| last4 = Cervera \| first4 = J. \| last5 = Haase \| first5 = D. \| last6 = Schanz \| first6 = J. \| last7 = García-Manero \| first7 = G. \| last8 = Del Cañizo \| first8 = C. \| last9 = Sanz \| first9 = GF. \| title = Clinical impact of the clone size in MDS cases with monosomy 7 or 7q deletion, trisomy 8, 20q deletion and loss of Y chromosome. \| journal = Leuk Res \| volume = \| issue = \| pages = \| month = Jan \| year = 2011 \| doi = 10.1016/j.leukres.2011.01.003 \| PMID = 21269692 }}

Michael: /* ISH */ +OMIM

2011-05-12T17:15:15Z

ISH: +OMIM

← Older revision		Revision as of 17:15, 12 May 2011
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	\| Tx (imatinib)		\| Tx (imatinib)
	\|-		\|-
	\| MLL		\| MLL<ref>{{OMIM\|159555}}</ref>
	\| ALL or AML		\| ALL or AML
	\| rearrangment --> marker of poor prognosis<ref>{{Cite journal \| last1 = Liedtke \| first1 = M. \| last2 = Cleary \| first2 = ML. \| title = Therapeutic targeting of MLL. \| journal = Blood \| volume = 113 \| issue = 24 \| pages = 6061-8 \| month = Jun \| year = 2009 \| doi = 10.1182/blood-2008-12-197061 \| PMID = 19289854 }}		\| rearrangment --> marker of poor prognosis<ref>{{Cite journal \| last1 = Liedtke \| first1 = M. \| last2 = Cleary \| first2 = ML. \| title = Therapeutic targeting of MLL. \| journal = Blood \| volume = 113 \| issue = 24 \| pages = 6061-8 \| month = Jun \| year = 2009 \| doi = 10.1182/blood-2008-12-197061 \| PMID = 19289854 }}

Michael: /* ISH */

2011-05-12T17:14:01Z

ISH

← Older revision		Revision as of 17:14, 12 May 2011
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	\| MLL		\| MLL
	\| ALL or AML		\| ALL or AML
	\| ?		\| rearrangment --> marker of poor prognosis<ref>{{Cite journal \| last1 = Liedtke \| first1 = M. \| last2 = Cleary \| first2 = ML. \| title = Therapeutic targeting of MLL. \| journal = Blood \| volume = 113 \| issue = 24 \| pages = 6061-8 \| month = Jun \| year = 2009 \| doi = 10.1182/blood-2008-12-197061 \| PMID = 19289854 }}
			</ref>
	\|-		\|-
	\| MYC		\| MYC

Michael: /* Karyotyping */

2011-05-12T16:58:33Z

Karyotyping

← Older revision		Revision as of 16:58, 12 May 2011
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	*5q deletion seen in myelodysplastic syndromes.<ref>{{Cite journal \| last1 = Nimer \| first1 = SD. \| title = Clinical management of myelodysplastic syndromes with interstitial deletion of chromosome 5q. \| journal = J Clin Oncol \| volume = 24 \| issue = 16 \| pages = 2576-82 \| month = Jun \| year = 2006 \| doi = 10.1200/JCO.2005.03.6715 \| PMID = 16735711 }}		*5q deletion seen in myelodysplastic syndromes.<ref>{{Cite journal \| last1 = Nimer \| first1 = SD. \| title = Clinical management of myelodysplastic syndromes with interstitial deletion of chromosome 5q. \| journal = J Clin Oncol \| volume = 24 \| issue = 16 \| pages = 2576-82 \| month = Jun \| year = 2006 \| doi = 10.1200/JCO.2005.03.6715 \| PMID = 16735711 }}
	</ref>		</ref>
			*Y deletion in [[MDS]]<ref name=pmid21269692>{{Cite journal \| last1 = Mallo \| first1 = M. \| last2 = Luño \| first2 = E. \| last3 = Sanzo \| first3 = C. \| last4 = Cervera \| first4 = J. \| last5 = Haase \| first5 = D. \| last6 = Schanz \| first6 = J. \| last7 = García-Manero \| first7 = G. \| last8 = Del Cañizo \| first8 = C. \| last9 = Sanz \| first9 = GF. \| title = Clinical impact of the clone size in MDS cases with monosomy 7 or 7q deletion, trisomy 8, 20q deletion and loss of Y chromosome. \| journal = Leuk Res \| volume = \| issue = \| pages = \| month = Jan \| year = 2011 \| doi = 10.1016/j.leukres.2011.01.003 \| PMID = 21269692 }}
			</ref> - relatively common in old men.

	==ISH==		==ISH==

Michael: 5q del

2011-05-12T15:37:39Z

5q del

← Older revision		Revision as of 15:37, 12 May 2011
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	Thsi article is a list of common '''cytogenetic tests'''. An introduction to cytogenetics is in the ''[[cytogenetics]]'' article.		Thsi article is a list of common '''cytogenetic tests'''. An introduction to cytogenetics is in the ''[[cytogenetics]]'' article.

			==Karyotyping==

			Findings:
			*5q deletion seen in myelodysplastic syndromes.<ref>{{Cite journal \| last1 = Nimer \| first1 = SD. \| title = Clinical management of myelodysplastic syndromes with interstitial deletion of chromosome 5q. \| journal = J Clin Oncol \| volume = 24 \| issue = 16 \| pages = 2576-82 \| month = Jun \| year = 2006 \| doi = 10.1200/JCO.2005.03.6715 \| PMID = 16735711 }}
			</ref>

			==ISH==
	Cytogenetic tests at one hospital:<ref>Kamel-Reid, Suzanne. University Health Network / Department of Pathology. Cancer Cytogenetics & Molecular Diagnostics Laboratories. Test Requisition. August 2010.</ref>		Cytogenetic tests at one hospital:<ref>Kamel-Reid, Suzanne. University Health Network / Department of Pathology. Cancer Cytogenetics & Molecular Diagnostics Laboratories. Test Requisition. August 2010.</ref>
	{\| class="wikitable sortable" style="margin-left:auto;margin-right:auto"		{\| class="wikitable sortable" style="margin-left:auto;margin-right:auto"

Michael: tweak lead in

2011-05-12T15:35:23Z

tweak lead in

← Older revision		Revision as of 15:35, 12 May 2011
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	~~The~~ article is a list of common '''cytogenetic tests'''.		Thsi article is a list of common '''cytogenetic tests'''. An introduction to cytogenetics is in the ''[[cytogenetics]]'' article.

	Cytogenetic tests at one hospital:<ref>Kamel-Reid, Suzanne. University Health Network / Department of Pathology. Cancer Cytogenetics & Molecular Diagnostics Laboratories. Test Requisition. August 2010.</ref>		Cytogenetic tests at one hospital:<ref>Kamel-Reid, Suzanne. University Health Network / Department of Pathology. Cancer Cytogenetics & Molecular Diagnostics Laboratories. Test Requisition. August 2010.</ref>