Cytokeratin 7 - Revision history

Michael: +image

2017-01-05T04:19:02Z

+image

← Older revision		Revision as of 04:19, 5 January 2017
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	[[Image:~~Adenocarcinoma~~-~~Acinar type~~ CK7 ~~(5494540614)~~.jpg\| thumb\|right\|CK7 immunostain in ~~acinar~~ [[~~adenocarcinoma of the lung~~]].]]		[[Image:Urothelial carcinoma - CK7 -- high mag.jpg\|thumb\|right\|CK7 immunostain in [[urothelial carcinoma]]. (WC)]]

	'''Cytokeratin 7''', also '''keratin 7''' and '''CK7''', is a common low molecular keratin and a very common [[immunostain]].<ref name=pmid11007036>{{Cite journal \| last1 = Chu \| first1 = P. \| last2 = Wu \| first2 = E. \| last3 = Weiss \| first3 = LM. \| title = Cytokeratin 7 and cytokeratin 20 expression in epithelial neoplasms: a survey of 435 cases. \| journal = Mod Pathol \| volume = 13 \| issue = 9 \| pages = 962-72 \| month = Sep \| year = 2000 \| doi = 10.1038/modpathol.3880175 \| PMID = 11007036 }}</ref>		'''Cytokeratin 7''', also '''keratin 7''' and '''CK7''', is a common low molecular keratin and a very common [[immunostain]].<ref name=pmid11007036>{{Cite journal \| last1 = Chu \| first1 = P. \| last2 = Wu \| first2 = E. \| last3 = Weiss \| first3 = LM. \| title = Cytokeratin 7 and cytokeratin 20 expression in epithelial neoplasms: a survey of 435 cases. \| journal = Mod Pathol \| volume = 13 \| issue = 9 \| pages = 962-72 \| month = Sep \| year = 2000 \| doi = 10.1038/modpathol.3880175 \| PMID = 11007036 }}</ref>

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	*Esophageal adenocarcinoma.		*Esophageal adenocarcinoma.

			====Images====
			<gallery>
			Image:Adenocarcinoma - CK7 immunostain (5762463282).jpg \| Adenocarcinoma of the lung. (WC/Yale Rosen)
			Image:Adenocarcinoma-Acinar type CK7 (5494540614).jpg\| CK7 immunostain in acinar [[adenocarcinoma of the lung]]. (WC)
			</gallery>
	==Negative==		==Negative==
	===Classic negative===		===Classic negative===
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	* † Most other common types are CK7 +ve ([[papillary RCC]], [[chromophobe RCC]], [[clear cell papillary RCC]])		* † Most other common types are CK7 +ve ([[papillary RCC]], [[chromophobe RCC]], [[clear cell papillary RCC]])
	* ‡ May be positive. In one series of head and neck SCC, conventional SCC: 7 +ve of 34 cases; [[basaloid squamous cell carcinoma]]: 24 +ve of 45 cases.<ref name=pmid20614292>{{Cite journal \| last1 = Winters \| first1 = R. \| last2 = Naud \| first2 = S. \| last3 = Evans \| first3 = MF. \| last4 = Trotman \| first4 = W. \| last5 = Kasznica \| first5 = P. \| last6 = Elhosseiny \| first6 = A. \| title = Ber-EP4, CK1, CK7 and CK14 are useful markers for basaloid squamous carcinoma: a study of 45 cases. \| journal = Head Neck Pathol \| volume = 2 \| issue = 4 \| pages = 265-71 \| month = Dec \| year = 2008 \| doi = 10.1007/s12105-008-0089-7 \| PMID = 20614292 }}</ref>		* ‡ May be positive. In one series of head and neck SCC, conventional SCC: 7 +ve of 34 cases; [[basaloid squamous cell carcinoma]]: 24 +ve of 45 cases.<ref name=pmid20614292>{{Cite journal \| last1 = Winters \| first1 = R. \| last2 = Naud \| first2 = S. \| last3 = Evans \| first3 = MF. \| last4 = Trotman \| first4 = W. \| last5 = Kasznica \| first5 = P. \| last6 = Elhosseiny \| first6 = A. \| title = Ber-EP4, CK1, CK7 and CK14 are useful markers for basaloid squamous carcinoma: a study of 45 cases. \| journal = Head Neck Pathol \| volume = 2 \| issue = 4 \| pages = 265-71 \| month = Dec \| year = 2008 \| doi = 10.1007/s12105-008-0089-7 \| PMID = 20614292 }}</ref>
			====Images====
	<gallery>		<gallery>
	~~File:Adenocarcinoma - CK7 immunostain (5762463282).jpg \| Adenocarcinoma of the lung. (WC/Yale Rosen)~~
	File:Lymphoma - lung - CK7 -- intermed mag.jpg\|Entrapped CK7-positive lung parenchyma within a lymphoma. (WC)		File:Lymphoma - lung - CK7 -- intermed mag.jpg\|Entrapped CK7-positive lung parenchyma within a lymphoma. (WC)
	</gallery>		</gallery>

Michael at 04:55, 3 August 2016

2016-08-03T04:55:34Z

← Older revision		Revision as of 04:55, 3 August 2016
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	[[Image:Adenocarcinoma-Acinar type CK7 (5494540614).jpg\| thumb\|right\|CK7 immunostain in acinar [[adenocarcinoma of the lung]].]]		[[Image:Adenocarcinoma-Acinar type CK7 (5494540614).jpg\| thumb\|right\|CK7 immunostain in acinar [[adenocarcinoma of the lung]].]]

	'''Cytokeratin 7''', also '''keratin 7''' and '''CK7''', is a common low molecular keratin and a very common [[immunostain]].<ref name=pmid11007036>{{Cite journal \| last1 = Chu \| first1 = P. \| last2 = Wu \| first2 = E. \| last3 = Weiss \| first3 = LM. \| title = Cytokeratin 7 and cytokeratin 20 expression in epithelial neoplasms: a survey of 435 cases. \| journal = Mod Pathol \| volume = 13 \| issue = 9 \| pages = 962-72 \| month = Sep \| year = 2000 \| doi = 10.1038/modpathol.3880175 \| PMID = 11007036 }}</ref>		'''Cytokeratin 7''', also '''keratin 7''' and '''CK7''', is a common low molecular keratin and a very common [[immunostain]].<ref name=pmid11007036>{{Cite journal \| last1 = Chu \| first1 = P. \| last2 = Wu \| first2 = E. \| last3 = Weiss \| first3 = LM. \| title = Cytokeratin 7 and cytokeratin 20 expression in epithelial neoplasms: a survey of 435 cases. \| journal = Mod Pathol \| volume = 13 \| issue = 9 \| pages = 962-72 \| month = Sep \| year = 2000 \| doi = 10.1038/modpathol.3880175 \| PMID = 11007036 }}</ref>

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	* ‡ May be positive. In one series of head and neck SCC, conventional SCC: 7 +ve of 34 cases; [[basaloid squamous cell carcinoma]]: 24 +ve of 45 cases.<ref name=pmid20614292>{{Cite journal \| last1 = Winters \| first1 = R. \| last2 = Naud \| first2 = S. \| last3 = Evans \| first3 = MF. \| last4 = Trotman \| first4 = W. \| last5 = Kasznica \| first5 = P. \| last6 = Elhosseiny \| first6 = A. \| title = Ber-EP4, CK1, CK7 and CK14 are useful markers for basaloid squamous carcinoma: a study of 45 cases. \| journal = Head Neck Pathol \| volume = 2 \| issue = 4 \| pages = 265-71 \| month = Dec \| year = 2008 \| doi = 10.1007/s12105-008-0089-7 \| PMID = 20614292 }}</ref>		* ‡ May be positive. In one series of head and neck SCC, conventional SCC: 7 +ve of 34 cases; [[basaloid squamous cell carcinoma]]: 24 +ve of 45 cases.<ref name=pmid20614292>{{Cite journal \| last1 = Winters \| first1 = R. \| last2 = Naud \| first2 = S. \| last3 = Evans \| first3 = MF. \| last4 = Trotman \| first4 = W. \| last5 = Kasznica \| first5 = P. \| last6 = Elhosseiny \| first6 = A. \| title = Ber-EP4, CK1, CK7 and CK14 are useful markers for basaloid squamous carcinoma: a study of 45 cases. \| journal = Head Neck Pathol \| volume = 2 \| issue = 4 \| pages = 265-71 \| month = Dec \| year = 2008 \| doi = 10.1007/s12105-008-0089-7 \| PMID = 20614292 }}</ref>
	<gallery>		<gallery>
	File:Adenocarcinoma - CK7 immunostain (5762463282).jpg \| Adenocarcinoma of the lung (WC/Yale Rosen)		File:Adenocarcinoma - CK7 immunostain (5762463282).jpg \| Adenocarcinoma of the lung. (WC/Yale Rosen)
			File:Lymphoma - lung - CK7 -- intermed mag.jpg\|Entrapped CK7-positive lung parenchyma within a lymphoma. (WC)
	</gallery>		</gallery>

Michael: /* Classic negative */

2016-03-23T19:10:48Z

Classic negative

← Older revision		Revision as of 19:10, 23 March 2016
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	==Negative==		==Negative==
	===Classic negative===		===Classic negative===
	*Kidney<ref name=pmid11007036/> ([[clear cell renal cell carcinoma]]). ‡		*Kidney<ref name=pmid11007036/> ([[clear cell renal cell carcinoma]]). †
	*Colon and rectum.<ref name=pmid11007036/>		*Colon and rectum.<ref name=pmid11007036/>
	*Prostate.<ref name=pmid11007036/>		*Prostate.<ref name=pmid11007036/>
	*Thymus.<ref name=pmid11007036/>		*Thymus.<ref name=pmid11007036/>
	*[[Squamous cell carcinoma]]. †		*[[Squamous cell carcinoma]]. ‡

	Notes:		Notes:
	* ‡ Most other common types are CK7 +ve ([[papillary RCC]], [[chromophobe RCC]], [[clear cell papillary RCC]])		* † Most other common types are CK7 +ve ([[papillary RCC]], [[chromophobe RCC]], [[clear cell papillary RCC]])
	* † May be positive. In one series of head and neck SCC: conventional SCC 7 +ve of 34 cases, [[basaloid squamous cell carcinoma]] 24 +ve of 45 cases.<ref name=pmid20614292>{{Cite journal \| last1 = Winters \| first1 = R. \| last2 = Naud \| first2 = S. \| last3 = Evans \| first3 = MF. \| last4 = Trotman \| first4 = W. \| last5 = Kasznica \| first5 = P. \| last6 = Elhosseiny \| first6 = A. \| title = Ber-EP4, CK1, CK7 and CK14 are useful markers for basaloid squamous carcinoma: a study of 45 cases. \| journal = Head Neck Pathol \| volume = 2 \| issue = 4 \| pages = 265-71 \| month = Dec \| year = 2008 \| doi = 10.1007/s12105-008-0089-7 \| PMID = 20614292 }}</ref>		* ‡ May be positive. In one series of head and neck SCC, conventional SCC: 7 +ve of 34 cases; [[basaloid squamous cell carcinoma]]: 24 +ve of 45 cases.<ref name=pmid20614292>{{Cite journal \| last1 = Winters \| first1 = R. \| last2 = Naud \| first2 = S. \| last3 = Evans \| first3 = MF. \| last4 = Trotman \| first4 = W. \| last5 = Kasznica \| first5 = P. \| last6 = Elhosseiny \| first6 = A. \| title = Ber-EP4, CK1, CK7 and CK14 are useful markers for basaloid squamous carcinoma: a study of 45 cases. \| journal = Head Neck Pathol \| volume = 2 \| issue = 4 \| pages = 265-71 \| month = Dec \| year = 2008 \| doi = 10.1007/s12105-008-0089-7 \| PMID = 20614292 }}</ref>
	<gallery>		<gallery>
	File:Adenocarcinoma - CK7 immunostain (5762463282).jpg \| Adenocarcinoma of the lung (WC/Yale Rosen)		File:Adenocarcinoma - CK7 immunostain (5762463282).jpg \| Adenocarcinoma of the lung (WC/Yale Rosen)

Michael: /* Negative */

2016-03-23T19:09:33Z

Negative

← Older revision		Revision as of 19:09, 23 March 2016
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	*Prostate.<ref name=pmid11007036/>		*Prostate.<ref name=pmid11007036/>
	*Thymus.<ref name=pmid11007036/>		*Thymus.<ref name=pmid11007036/>
	*[[Squamous cell carcinoma]].		*[[Squamous cell carcinoma]]. †

	Notes:		Notes:
	* ‡ Most other common types are CK7 +ve ([[papillary RCC]], [[chromophobe RCC]], [[clear cell papillary RCC]])		* ‡ Most other common types are CK7 +ve ([[papillary RCC]], [[chromophobe RCC]], [[clear cell papillary RCC]])
			* † May be positive. In one series of head and neck SCC: conventional SCC 7 +ve of 34 cases, [[basaloid squamous cell carcinoma]] 24 +ve of 45 cases.<ref name=pmid20614292>{{Cite journal \| last1 = Winters \| first1 = R. \| last2 = Naud \| first2 = S. \| last3 = Evans \| first3 = MF. \| last4 = Trotman \| first4 = W. \| last5 = Kasznica \| first5 = P. \| last6 = Elhosseiny \| first6 = A. \| title = Ber-EP4, CK1, CK7 and CK14 are useful markers for basaloid squamous carcinoma: a study of 45 cases. \| journal = Head Neck Pathol \| volume = 2 \| issue = 4 \| pages = 265-71 \| month = Dec \| year = 2008 \| doi = 10.1007/s12105-008-0089-7 \| PMID = 20614292 }}</ref>
	<gallery>		<gallery>
	File:Adenocarcinoma - CK7 immunostain (5762463282).jpg \| Adenocarcinoma of the lung (WC/Yale Rosen)		File:Adenocarcinoma - CK7 immunostain (5762463282).jpg \| Adenocarcinoma of the lung (WC/Yale Rosen)

Michael: /* See also */

2016-01-28T22:33:09Z

Jensflorian: +image

2015-10-08T13:30:18Z

+image

← Older revision		Revision as of 13:30, 8 October 2015
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	Notes:		Notes:
	* ‡ Most other common types are CK7 +ve ([[papillary RCC]], [[chromophobe RCC]], [[clear cell papillary RCC]])		* ‡ Most other common types are CK7 +ve ([[papillary RCC]], [[chromophobe RCC]], [[clear cell papillary RCC]])

			<gallery>
			File:Adenocarcinoma - CK7 immunostain (5762463282).jpg \| Adenocarcinoma of the lung (WC/Yale Rosen)
			</gallery>

	==See also==		==See also==

Michael: /* Classic positive */

2015-08-21T03:10:15Z

Classic positive

← Older revision		Revision as of 03:10, 21 August 2015
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	*[[Endometrium]].		*[[Endometrium]].
	*[[Salivary gland]].		*[[Salivary gland]].
	*Lung ([[lung adenocarcinoma\|adenocarcinoma~~]], [[small cell carcinoma of the lung\|small cell~~]]).		*Lung ([[lung adenocarcinoma\|adenocarcinoma]]).
	*[[Thyroid gland]].		*[[Thyroid gland]].
	*[[Mesothelium]].		*[[Mesothelium]].

Michael: /* Classic positive */

2015-08-21T03:02:50Z

Classic positive

← Older revision		Revision as of 03:02, 21 August 2015
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	==Positive==		==Positive==
	===Classic positive===		===Classic positive===
	*Ovary.		*[[Ovary]].
	*Breast.		*[[Breast]].
	*Endometrium.		*[[Endometrium]].
	*Salivary gland.		*[[Salivary gland]].
	*Lung ([[lung adenocarcinoma\|adenocarcinoma]], [[small cell carcinoma of the lung\|small cell]]).		*Lung ([[lung adenocarcinoma\|adenocarcinoma]], [[small cell carcinoma of the lung\|small cell]]).
	*Thyroid.		*[[Thyroid gland]].
	*Mesothelium.		*[[Mesothelium]].

			*Pancreas.
			*Stomach.
			*Urothelial carcinoma.
			*Esophageal adenocarcinoma.

	==Negative==		==Negative==

Michael: Created page with "CK7 immunostain in acinar [[adenocarcinoma of the lung.]] '''Cytokeratin 7''', also '''keratin 7''' and..."

2015-08-21T03:00:34Z

Created page with " thumb|right|CK7 immunostain in acinar [[adenocarcinoma of the lung.]] '''Cytokeratin 7''', also '''keratin 7''' and..."

New page

[[Image:Adenocarcinoma-Acinar type CK7 (5494540614).jpg| thumb|right|CK7 immunostain in acinar [[adenocarcinoma of the lung]].]]
'''Cytokeratin 7''', also '''keratin 7''' and '''CK7''', is a common low molecular keratin and a very common [[immunostain]].<ref name=pmid11007036>{{Cite journal | last1 = Chu | first1 = P. | last2 = Wu | first2 = E. | last3 = Weiss | first3 = LM. | title = Cytokeratin 7 and cytokeratin 20 expression in epithelial neoplasms: a survey of 435 cases. | journal = Mod Pathol | volume = 13 | issue = 9 | pages = 962-72 | month = Sep | year = 2000 | doi = 10.1038/modpathol.3880175 | PMID = 11007036 }}</ref>

==Positive==
===Classic positive===
*Ovary.
*Breast.
*Endometrium.
*Salivary gland.
*Lung ([[lung adenocarcinoma|adenocarcinoma]], [[small cell carcinoma of the lung|small cell]]).
*Thyroid.
*Mesothelium.

==Negative==
===Classic negative===
*Kidney<ref name=pmid11007036/> ([[clear cell renal cell carcinoma]]). ‡
*Colon and rectum.<ref name=pmid11007036/>
*Prostate.<ref name=pmid11007036/>
*Thymus.<ref name=pmid11007036/>
*[[Squamous cell carcinoma]].

Notes:
* ‡ Most other common types are CK7 +ve ([[papillary RCC]], [[chromophobe RCC]], [[clear cell papillary RCC]])

==See also==
*[[Cytokeratin 20]].
*[[Cytokeratin 19]].

==References==
{{Reflist|1}}

[[Category:Immunohistochemistry]]

← Older revision		Revision as of 22:33, 28 January 2016
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	*[[Cytokeratin 20]].		*[[Cytokeratin 20]].
	*[[Cytokeratin 19]].		*[[Cytokeratin 19]].
			*[[CAM5.2]].

	==References==		==References==