Digital papillary adenocarcinoma - Revision history

Michael: /* Microscopic */

2014-06-27T17:36:11Z

Microscopic

← Older revision		Revision as of 17:36, 27 June 2014
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	DDx:		DDx:
	*[[Basal cell carcinoma]].		*[[Basal cell carcinoma]].
			*[[Papillary eccrine adenoma]].
	*Other basaloid tumours.		*Other basaloid tumours.

Michael: /* General */

2014-06-22T02:57:58Z

General

← Older revision		Revision as of 02:57, 22 June 2014
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	*Very rare.		*Very rare.
	*Aggressive - amputation is typically recommended.<ref>{{cite journal \|author=Hsu HC, Ho CY, Chen CH, Yang CH, Hong HS, Chuang YH \|title=Aggressive digital papillary adenocarcinoma: a review \|journal=Clin. Exp. Dermatol. \|volume=35 \|issue=2 \|pages=113–9 \|year=2010 \|month=March \|pmid=19874325 \|doi=10.1111/j.1365-2230.2009.03490.x \|url=}}</ref>		*Aggressive - amputation is typically recommended.<ref>{{cite journal \|author=Hsu HC, Ho CY, Chen CH, Yang CH, Hong HS, Chuang YH \|title=Aggressive digital papillary adenocarcinoma: a review \|journal=Clin. Exp. Dermatol. \|volume=35 \|issue=2 \|pages=113–9 \|year=2010 \|month=March \|pmid=19874325 \|doi=10.1111/j.1365-2230.2009.03490.x \|url=}}</ref>
	*Typically males 50-70 years old.		*Typically males 50-80 years old.
	**May be seen in adolescents.<ref>{{cite journal \|author=Frey J, Shimek C, Woodmansee C, ''et al.'' \|title=Aggressive digital papillary adenocarcinoma: a report of two diseases and review of the literature \|journal=J. Am. Acad. Dermatol. \|volume=60 \|issue=2 \|pages=331–9 \|year=2009 \|month=February \|pmid=18819728 \|doi=10.1016/j.jaad.2008.07.038 \|url=}}</ref>		**May be seen in adolescents.<ref>{{cite journal \|author=Frey J, Shimek C, Woodmansee C, ''et al.'' \|title=Aggressive digital papillary adenocarcinoma: a report of two diseases and review of the literature \|journal=J. Am. Acad. Dermatol. \|volume=60 \|issue=2 \|pages=331–9 \|year=2009 \|month=February \|pmid=18819728 \|doi=10.1016/j.jaad.2008.07.038 \|url=}}</ref>

Michael at 02:56, 22 June 2014

2014-06-22T02:56:32Z

← Older revision		Revision as of 02:56, 22 June 2014
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			{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image =
			\| Width =
			\| Caption =
			\| Synonyms = aggressive digital papillary adenocarcinoma
			\| Micro =
			\| Subtypes =
			\| LMDDx = [[basal cell carcinoma]], other basaloid tumours
			\| Stains =
			\| IHC = pankeratin +ve, CEA +ve (edge of ducts/spaces), EMA +ve (edge of ducts/spaces), S-100 +ve (luminal cells), SMA +ve (outer myoepithelial cell layer), p63 +ve (outer myoepithelial cell layer)
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross =
			\| Grossing =
			\| Site = [[skin]] - digits (fingers or toes)
			\| Assdx =
			\| Syndromes =
			\| Clinicalhx =
			\| Signs =
			\| Symptoms =
			\| Prevalence = very rare
			\| Bloodwork =
			\| Rads =
			\| Endoscopy =
			\| Prognosis = aggressive
			\| Other =
			\| ClinDDx =
			\| Tx = ampuation
			}}
	'''Digital papillary adenocarcinoma''' (abbreviated '''DPA'''), also '''aggressive digital papillary adenocarcinoma''' (abbreviated '''ADPA'''), is a rare [[malignant]] [[skin]] tumour.<ref name=pmid23026931>{{cite journal \|author=Suchak R, Wang WL, Prieto VG, ''et al.'' \|title=Cutaneous digital papillary adenocarcinoma: a clinicopathologic study of 31 cases of a rare neoplasm with new observations \|journal=Am. J. Surg. Pathol. \|volume=36 \|issue=12 \|pages=1883–91 \|year=2012 \|month=December \|pmid=23026931 \|doi=10.1097/PAS.0b013e31826320ec \|url=}}</ref>		'''Digital papillary adenocarcinoma''' (abbreviated '''DPA'''), also '''aggressive digital papillary adenocarcinoma''' (abbreviated '''ADPA'''), is a rare [[malignant]] [[skin]] tumour.<ref name=pmid23026931>{{cite journal \|author=Suchak R, Wang WL, Prieto VG, ''et al.'' \|title=Cutaneous digital papillary adenocarcinoma: a clinicopathologic study of 31 cases of a rare neoplasm with new observations \|journal=Am. J. Surg. Pathol. \|volume=36 \|issue=12 \|pages=1883–91 \|year=2012 \|month=December \|pmid=23026931 \|doi=10.1097/PAS.0b013e31826320ec \|url=}}</ref>

Michael at 02:33, 20 June 2014

2014-06-20T02:33:13Z

← Older revision		Revision as of 02:33, 20 June 2014
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	*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094519/figure/Fig3/ ADPA (nih.gov)].<ref>{{cite journal \|author=Gole GN, Tati SY, Deshpande AK, Gole SG \|title=Aggressive Digital Papillary Adenocarcinoma in a Young Female-a Rare Presentation \|journal=J Hand Microsurg \|volume=3 \|issue=1 \|pages=31–3 \|year=2011 \|month=June \|pmid=22654416 \|pmc=3094519 \|doi=10.1007/s12593-010-0028-1 \|url=}}</ref>		*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094519/figure/Fig3/ ADPA (nih.gov)].<ref>{{cite journal \|author=Gole GN, Tati SY, Deshpande AK, Gole SG \|title=Aggressive Digital Papillary Adenocarcinoma in a Young Female-a Rare Presentation \|journal=J Hand Microsurg \|volume=3 \|issue=1 \|pages=31–3 \|year=2011 \|month=June \|pmid=22654416 \|pmc=3094519 \|doi=10.1007/s12593-010-0028-1 \|url=}}</ref>
	*[http://escholarship.org/uc/item/212957kk.pdf ADPA (escholarship.org)].<ref name=pmid24612571>{{cite journal \|author=Jefferson J, Thompson C, Rich P \|title=A slowly enlarging mass on the finger \|journal=Dermatol. Online J. \|volume=20 \|issue=2 \|pages= \|year=2014 \|month=February \|pmid=24612571 \|doi= \|url=}}</ref>		*[http://escholarship.org/uc/item/212957kk.pdf ADPA (escholarship.org)].<ref name=pmid24612571>{{cite journal \|author=Jefferson J, Thompson C, Rich P \|title=A slowly enlarging mass on the finger \|journal=Dermatol. Online J. \|volume=20 \|issue=2 \|pages= \|year=2014 \|month=February \|pmid=24612571 \|doi= \|url=}}</ref>

			==IHC==
			Features:<ref name=pmid23026931/>
			*Pankeratin +ve.
			*CEA +ve (edge of ducts/spaces).
			*EMA +ve (edge of ducts/spaces).
			*S-100 +ve (luminal cells).
			*SMA +ve (outer myoepithelial cell layer).
			*p63 +ve (outer myoepithelial cell layer).

	==See also==		==See also==

Michael: /* Microscopic */

2014-06-20T02:17:00Z

Microscopic

← Older revision		Revision as of 02:17, 20 June 2014
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	**Tubular structures.		**Tubular structures.
	*Basaloid cells usually with mild-to-moderate atypia.		*Basaloid cells usually with mild-to-moderate atypia.
			*Fibrous stroma.<ref name=pmid24612571/>

	DDx:		DDx:
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	*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094519/figure/Fig3/ ADPA (nih.gov)].<ref>{{cite journal \|author=Gole GN, Tati SY, Deshpande AK, Gole SG \|title=Aggressive Digital Papillary Adenocarcinoma in a Young Female-a Rare Presentation \|journal=J Hand Microsurg \|volume=3 \|issue=1 \|pages=31–3 \|year=2011 \|month=June \|pmid=22654416 \|pmc=3094519 \|doi=10.1007/s12593-010-0028-1 \|url=}}</ref>		*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094519/figure/Fig3/ ADPA (nih.gov)].<ref>{{cite journal \|author=Gole GN, Tati SY, Deshpande AK, Gole SG \|title=Aggressive Digital Papillary Adenocarcinoma in a Young Female-a Rare Presentation \|journal=J Hand Microsurg \|volume=3 \|issue=1 \|pages=31–3 \|year=2011 \|month=June \|pmid=22654416 \|pmc=3094519 \|doi=10.1007/s12593-010-0028-1 \|url=}}</ref>
	*[http://escholarship.org/uc/item/212957kk.pdf ADPA (escholarship.org)].<ref name=pmid24612571>{{cite journal \|author=Jefferson J, Thompson C, Rich P \|title=A slowly enlarging mass on the finger \|journal=Dermatol. Online J. \|volume=20 \|issue=2 \|pages= \|year=2014 \|month=February \|pmid=24612571 \|doi= \|url=}}</ref>		*[http://escholarship.org/uc/item/212957kk.pdf ADPA (escholarship.org)].<ref name=pmid24612571>{{cite journal \|author=Jefferson J, Thompson C, Rich P \|title=A slowly enlarging mass on the finger \|journal=Dermatol. Online J. \|volume=20 \|issue=2 \|pages= \|year=2014 \|month=February \|pmid=24612571 \|doi= \|url=}}</ref>

	==See also==		==See also==
	*[[Dermatopathology]].		*[[Dermatopathology]].

Michael at 02:14, 20 June 2014

2014-06-20T02:14:45Z

← Older revision		Revision as of 02:14, 20 June 2014
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	*[http://www.indianjcancer.com/viewimage.asp?img=IndianJournalofCancer_2011_48_1_126_76641_u2.jpg ADPA (indianjcancer.com)].<ref name=pmid21330762>{{cite journal \|author=Rastrelli M, Soteldo J, Vitali GC, ''et al.'' \|title=Aggressive digital papillary adenocarcinoma \|journal=Indian J Cancer \|volume=48 \|issue=1 \|pages=126–7 \|year=2011 \|pmid=21330762 \|doi=10.4103/0019-509X.76641 \|url=}}</ref>		*[http://www.indianjcancer.com/viewimage.asp?img=IndianJournalofCancer_2011_48_1_126_76641_u2.jpg ADPA (indianjcancer.com)].<ref name=pmid21330762>{{cite journal \|author=Rastrelli M, Soteldo J, Vitali GC, ''et al.'' \|title=Aggressive digital papillary adenocarcinoma \|journal=Indian J Cancer \|volume=48 \|issue=1 \|pages=126–7 \|year=2011 \|pmid=21330762 \|doi=10.4103/0019-509X.76641 \|url=}}</ref>
	*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094519/figure/Fig3/ ADPA (nih.gov)].<ref>{{cite journal \|author=Gole GN, Tati SY, Deshpande AK, Gole SG \|title=Aggressive Digital Papillary Adenocarcinoma in a Young Female-a Rare Presentation \|journal=J Hand Microsurg \|volume=3 \|issue=1 \|pages=31–3 \|year=2011 \|month=June \|pmid=22654416 \|pmc=3094519 \|doi=10.1007/s12593-010-0028-1 \|url=}}</ref>		*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094519/figure/Fig3/ ADPA (nih.gov)].<ref>{{cite journal \|author=Gole GN, Tati SY, Deshpande AK, Gole SG \|title=Aggressive Digital Papillary Adenocarcinoma in a Young Female-a Rare Presentation \|journal=J Hand Microsurg \|volume=3 \|issue=1 \|pages=31–3 \|year=2011 \|month=June \|pmid=22654416 \|pmc=3094519 \|doi=10.1007/s12593-010-0028-1 \|url=}}</ref>
			*[http://escholarship.org/uc/item/212957kk.pdf ADPA (escholarship.org)].<ref name=pmid24612571>{{cite journal \|author=Jefferson J, Thompson C, Rich P \|title=A slowly enlarging mass on the finger \|journal=Dermatol. Online J. \|volume=20 \|issue=2 \|pages= \|year=2014 \|month=February \|pmid=24612571 \|doi= \|url=}}</ref>
	==See also==		==See also==
	*[[Dermatopathology]].		*[[Dermatopathology]].

Michael: /* Microscopic */

2014-06-20T02:12:00Z

Microscopic

← Older revision		Revision as of 02:12, 20 June 2014
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	===Images===		===Images===
	*[http://www.indianjcancer.com/viewimage.asp?img=IndianJournalofCancer_2011_48_1_126_76641_u2.jpg ADPA (indianjcancer.com)].<ref name=pmid21330762>{{cite journal \|author=Rastrelli M, Soteldo J, Vitali GC, ''et al.'' \|title=Aggressive digital papillary adenocarcinoma \|journal=Indian J Cancer \|volume=48 \|issue=1 \|pages=126–7 \|year=2011 \|pmid=21330762 \|doi=10.4103/0019-509X.76641 \|url=}}</ref>		*[http://www.indianjcancer.com/viewimage.asp?img=IndianJournalofCancer_2011_48_1_126_76641_u2.jpg ADPA (indianjcancer.com)].<ref name=pmid21330762>{{cite journal \|author=Rastrelli M, Soteldo J, Vitali GC, ''et al.'' \|title=Aggressive digital papillary adenocarcinoma \|journal=Indian J Cancer \|volume=48 \|issue=1 \|pages=126–7 \|year=2011 \|pmid=21330762 \|doi=10.4103/0019-509X.76641 \|url=}}</ref>
			*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3094519/figure/Fig3/ ADPA (nih.gov)].<ref>{{cite journal \|author=Gole GN, Tati SY, Deshpande AK, Gole SG \|title=Aggressive Digital Papillary Adenocarcinoma in a Young Female-a Rare Presentation \|journal=J Hand Microsurg \|volume=3 \|issue=1 \|pages=31–3 \|year=2011 \|month=June \|pmid=22654416 \|pmc=3094519 \|doi=10.1007/s12593-010-0028-1 \|url=}}</ref>

	==See also==		==See also==

Michael at 02:09, 20 June 2014

2014-06-20T02:09:30Z

← Older revision		Revision as of 02:09, 20 June 2014
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	'''Digital papillary adenocarcinoma''', also '''aggressive digital papillary adenocarcinoma''', is a rare [[malignant]] [[skin]] tumour.<ref name=pmid23026931>{{cite journal \|author=Suchak R, Wang WL, Prieto VG, ''et al.'' \|title=Cutaneous digital papillary adenocarcinoma: a clinicopathologic study of 31 cases of a rare neoplasm with new observations \|journal=Am. J. Surg. Pathol. \|volume=36 \|issue=12 \|pages=1883–91 \|year=2012 \|month=December \|pmid=23026931 \|doi=10.1097/PAS.0b013e31826320ec \|url=}}</ref>		'''Digital papillary adenocarcinoma''' (abbreviated '''DPA'''), also '''aggressive digital papillary adenocarcinoma''' (abbreviated '''ADPA'''), is a rare [[malignant]] [[skin]] tumour.<ref name=pmid23026931>{{cite journal \|author=Suchak R, Wang WL, Prieto VG, ''et al.'' \|title=Cutaneous digital papillary adenocarcinoma: a clinicopathologic study of 31 cases of a rare neoplasm with new observations \|journal=Am. J. Surg. Pathol. \|volume=36 \|issue=12 \|pages=1883–91 \|year=2012 \|month=December \|pmid=23026931 \|doi=10.1097/PAS.0b013e31826320ec \|url=}}</ref>

	==General==		==General==
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	*[[Basal cell carcinoma]].		*[[Basal cell carcinoma]].
	*Other basaloid tumours.		*Other basaloid tumours.

			===Images===
			*[http://www.indianjcancer.com/viewimage.asp?img=IndianJournalofCancer_2011_48_1_126_76641_u2.jpg ADPA (indianjcancer.com)].<ref name=pmid21330762>{{cite journal \|author=Rastrelli M, Soteldo J, Vitali GC, ''et al.'' \|title=Aggressive digital papillary adenocarcinoma \|journal=Indian J Cancer \|volume=48 \|issue=1 \|pages=126–7 \|year=2011 \|pmid=21330762 \|doi=10.4103/0019-509X.76641 \|url=}}</ref>

	==See also==		==See also==

Michael at 02:05, 20 June 2014

2014-06-20T02:05:49Z

← Older revision		Revision as of 02:05, 20 June 2014
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	'''Digital papillary adenocarcinoma''' is a rare [[malignant]] [[skin]] tumour.<ref name=pmid23026931>{{cite journal \|author=Suchak R, Wang WL, Prieto VG, ''et al.'' \|title=Cutaneous digital papillary adenocarcinoma: a clinicopathologic study of 31 cases of a rare neoplasm with new observations \|journal=Am. J. Surg. Pathol. \|volume=36 \|issue=12 \|pages=1883–91 \|year=2012 \|month=December \|pmid=23026931 \|doi=10.1097/PAS.0b013e31826320ec \|url=}}</ref>		'''Digital papillary adenocarcinoma''', also '''aggressive digital papillary adenocarcinoma''', is a rare [[malignant]] [[skin]] tumour.<ref name=pmid23026931>{{cite journal \|author=Suchak R, Wang WL, Prieto VG, ''et al.'' \|title=Cutaneous digital papillary adenocarcinoma: a clinicopathologic study of 31 cases of a rare neoplasm with new observations \|journal=Am. J. Surg. Pathol. \|volume=36 \|issue=12 \|pages=1883–91 \|year=2012 \|month=December \|pmid=23026931 \|doi=10.1097/PAS.0b013e31826320ec \|url=}}</ref>

	==General==		==General==
	*Very rare.		*Very rare.
	*Aggressive.		*Aggressive - amputation is typically recommended.<ref>{{cite journal \|author=Hsu HC, Ho CY, Chen CH, Yang CH, Hong HS, Chuang YH \|title=Aggressive digital papillary adenocarcinoma: a review \|journal=Clin. Exp. Dermatol. \|volume=35 \|issue=2 \|pages=113–9 \|year=2010 \|month=March \|pmid=19874325 \|doi=10.1111/j.1365-2230.2009.03490.x \|url=}}</ref>
			*Typically males 50-70 years old.
			**May be seen in adolescents.<ref>{{cite journal \|author=Frey J, Shimek C, Woodmansee C, ''et al.'' \|title=Aggressive digital papillary adenocarcinoma: a report of two diseases and review of the literature \|journal=J. Am. Acad. Dermatol. \|volume=60 \|issue=2 \|pages=331–9 \|year=2009 \|month=February \|pmid=18819728 \|doi=10.1016/j.jaad.2008.07.038 \|url=}}</ref>

	==Gross==		==Gross==

Michael: /* =References */

2014-06-19T20:42:12Z

=References

← Older revision		Revision as of 20:42, 19 June 2014
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	*[[Dermatopathology]].		*[[Dermatopathology]].

	==References=		==References==
	{{reflist\|2}}		{{reflist\|2}}

	[[Category:Dermatopathology]]		[[Category:Dermatopathology]]
	[[Category:Diagnosis]]		[[Category:Diagnosis]]