Eosinophilic granulomatosis with polyangiitis - Revision history

Michael: similar name to what was prev Wegener's

2016-11-28T21:50:30Z

similar name to what was prev Wegener's

← Older revision		Revision as of 21:50, 28 November 2016
Line 35:		Line 35:
	It was previously known as '''Churg-Strauss syndrome'''.<ref name=pmid26051917>{{Cite journal \| last1 = Stone \| first1 = JR. \| last2 = Bruneval \| first2 = P. \| last3 = Angelini \| first3 = A. \| last4 = Bartoloni \| first4 = G. \| last5 = Basso \| first5 = C. \| last6 = Batoroeva \| first6 = L. \| last7 = Buja \| first7 = LM. \| last8 = Butany \| first8 = J. \| last9 = d'Amati \| first9 = G. \| title = Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association for European Cardiovascular Pathology: I. Inflammatory diseases. \| journal = Cardiovasc Pathol \| volume = 24 \| issue = 5 \| pages = 267-78 \| month = \| year = \| doi = 10.1016/j.carpath.2015.05.001 \| PMID = 26051917 }}</ref>		It was previously known as '''Churg-Strauss syndrome'''.<ref name=pmid26051917>{{Cite journal \| last1 = Stone \| first1 = JR. \| last2 = Bruneval \| first2 = P. \| last3 = Angelini \| first3 = A. \| last4 = Bartoloni \| first4 = G. \| last5 = Basso \| first5 = C. \| last6 = Batoroeva \| first6 = L. \| last7 = Buja \| first7 = LM. \| last8 = Butany \| first8 = J. \| last9 = d'Amati \| first9 = G. \| title = Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association for European Cardiovascular Pathology: I. Inflammatory diseases. \| journal = Cardiovasc Pathol \| volume = 24 \| issue = 5 \| pages = 267-78 \| month = \| year = \| doi = 10.1016/j.carpath.2015.05.001 \| PMID = 26051917 }}</ref>

			It should '''''not''''' be confused with ''[[granulomatosis with polyangiitis]]'', previously known as ''Wegener's granulomatosis''.

	==General==		==General==
	Defining features - memory device ''GAFE'':		Defining features - memory device ''GAFE'':

Michael at 21:35, 28 November 2016

2016-11-28T21:35:26Z

← Older revision		Revision as of 21:35, 28 November 2016
Line 23:		Line 23:
	\| Symptoms =		\| Symptoms =
	\| Prevalence = rare		\| Prevalence = rare
	\| Bloodwork =		\| Bloodwork = ANCA +ve/-ve
	\| Rads =		\| Rads =
	\| Endoscopy =		\| Endoscopy =
Line 52:		Line 52:
	Notes:		Notes:
	*Similar to [[Granulomatosis with polyangiitis]] (Wegener's granulomatosis) - classically c-ANCA +ve, and ''microscopic polyangiitis''.<ref>URL: [http://emedicine.medscape.com/article/334024-overview http://emedicine.medscape.com/article/334024-overview]. Accessed on: 22 January 2011.</ref>		*Similar to [[Granulomatosis with polyangiitis]] (Wegener's granulomatosis) - classically c-ANCA +ve, and ''microscopic polyangiitis''.<ref>URL: [http://emedicine.medscape.com/article/334024-overview http://emedicine.medscape.com/article/334024-overview]. Accessed on: 22 January 2011.</ref>
			*T<sub>H</sub>2 disease - like [[asthma]].<ref name=pmid25500434>{{Cite journal \| last1 = Greco \| first1 = A. \| last2 = Rizzo \| first2 = MI. \| last3 = De Virgilio \| first3 = A. \| last4 = Gallo \| first4 = A. \| last5 = Fusconi \| first5 = M. \| last6 = Ruoppolo \| first6 = G. \| last7 = Altissimi \| first7 = G. \| last8 = De Vincentiis \| first8 = M. \| title = Churg-Strauss syndrome. \| journal = Autoimmun Rev \| volume = 14 \| issue = 4 \| pages = 341-8 \| month = Apr \| year = 2015 \| doi = 10.1016/j.autrev.2014.12.004 \| PMID = 25500434 }}</ref>

	==Microscopic==		==Microscopic==

Michael at 21:30, 28 November 2016

2016-11-28T21:30:58Z

← Older revision		Revision as of 21:30, 28 November 2016
Line 4:		Line 4:
	\| Width =		\| Width =
	\| Caption = Eosinophilic granulomatosis with polyangiitis. [[H&E stain]].		\| Caption = Eosinophilic granulomatosis with polyangiitis. [[H&E stain]].
	\| Synonyms =		\| Synonyms = Churg-Strauss syndrome, Churg-Strauss disease
	\| Micro = small vessel [[vasculitis]] with abundant eosinophils and [[granuloma]]s		\| Micro = small vessel [[vasculitis]] with abundant eosinophils and [[granuloma]]s
	\| Subtypes =		\| Subtypes =

Michael: tweak

2016-11-28T21:30:35Z

tweak

← Older revision		Revision as of 21:30, 28 November 2016
Line 31:		Line 31:
	\| Tx =		\| Tx =
	}}		}}
	'''Eosinophilic granulomatosis with polyangiitis''', ~~previously known as~~ '''~~Churg-Strauss syndrome~~''',<ref ~~name=pmid26051917~~>{{Cite journal \| last1 = ~~Stone~~ \| first1 = JR. \| last2 = ~~Bruneval~~ \| first2 = P. \| last3 = ~~Angelini~~ \| first3 = A. \| last4 = ~~Bartoloni~~ \| first4 = G. \| last5 = ~~Basso~~ \| first5 = C. \| last6 = ~~Batoroeva~~ \| first6 = ~~L. \| last7 = Buja \| first7 = LM. \| last8 = Butany \| first8 = J. \| last9 = d'Amati \| first9 = G~~. \| title = ~~Consensus statement on surgical pathology~~ of ~~the aorta from the Society for Cardiovascular Pathology and the Association for European Cardiovascular Pathology: I. Inflammatory diseases~~. \| journal = ~~Cardiovasc Pathol~~ \| volume = 24 \| issue = 5 \| pages = ~~267~~-78 \| month = \| year = \| doi = 10.~~1016~~/j.~~carpath~~.~~2015~~.05.~~001~~ \| PMID = ~~26051917~~ }}</ref> is a type of [[vasculitis]].		'''Eosinophilic granulomatosis with polyangiitis''', abbreviated '''EGPA''',<ref>{{Cite journal \| last1 = Xu \| first1 = XL. \| last2 = Song \| first2 = W. \| last3 = Sui \| first3 = X. \| last4 = Song \| first4 = L. \| last5 = DU \| first5 = QN. \| last6 = Wang \| first6 = X. \| title = Radiological and Clinical Features of Eosinophilic Granulomatosis with Polyangiitis. \| journal = Zhongguo Yi Xue Ke Xue Yuan Xue Bao \| volume = 38 \| issue = 5 \| pages = 617-620 \| month = Oct \| year = 2016 \| doi = 10.3881/j.issn.1000-503X.2016.05.023 \| PMID = 27825424 }}</ref> is a type of [[vasculitis]].

			It was previously known as '''Churg-Strauss syndrome'''.<ref name=pmid26051917>{{Cite journal \| last1 = Stone \| first1 = JR. \| last2 = Bruneval \| first2 = P. \| last3 = Angelini \| first3 = A. \| last4 = Bartoloni \| first4 = G. \| last5 = Basso \| first5 = C. \| last6 = Batoroeva \| first6 = L. \| last7 = Buja \| first7 = LM. \| last8 = Butany \| first8 = J. \| last9 = d'Amati \| first9 = G. \| title = Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association for European Cardiovascular Pathology: I. Inflammatory diseases. \| journal = Cardiovasc Pathol \| volume = 24 \| issue = 5 \| pages = 267-78 \| month = \| year = \| doi = 10.1016/j.carpath.2015.05.001 \| PMID = 26051917 }}</ref>

	==General==		==General==
	Defining features - memory device ''GAFE'':		Defining features - memory device ''GAFE'':

Michael: /* General */

2016-11-28T21:26:19Z

General

← Older revision		Revision as of 21:26, 28 November 2016
Line 39:		Line 39:
	*'''F'''ever.		*'''F'''ever.
	*'''E'''osinophilia.		*'''E'''osinophilia.

			Other clinical features - may be present:<ref name=pmid27671089 >{{Cite journal \| last1 = Cottin \| first1 = V. \| last2 = Bel \| first2 = E. \| last3 = Bottero \| first3 = P. \| last4 = Dalhoff \| first4 = K. \| last5 = Humbert \| first5 = M. \| last6 = Lazor \| first6 = R. \| last7 = Sinico \| first7 = RA. \| last8 = Sivasothy \| first8 = P. \| last9 = Wechsler \| first9 = ME. \| title = Revisiting the systemic vasculitis in eosinophilic granulomatosis with polyangiitis (Churg-Strauss): A study of 157 patients by the Groupe d'Etudes et de Recherche sur les Maladies Orphelines Pulmonaires and the European Respiratory Society Taskforce on eosinophilic granulomatosis with polyangiitis (Churg-Strauss). \| journal = Autoimmun Rev \| volume = \| issue = \| pages = \| month = Sep \| year = 2016 \| doi = 10.1016/j.autrev.2016.09.018 \| PMID = 27671089 }}</ref>
			*ANCA.
			*Weight loss.
			*Myalgias.
			*Arthralgias
			*Glomerulonephritis.
			*Hematuria.

	Notes:		Notes:

Michael: fix typo

2016-11-28T21:19:13Z

fix typo

← Older revision		Revision as of 21:19, 28 November 2016
Line 7:		Line 7:
	\| Micro = small vessel [[vasculitis]] with abundant eosinophils and [[granuloma]]s		\| Micro = small vessel [[vasculitis]] with abundant eosinophils and [[granuloma]]s
	\| Subtypes =		\| Subtypes =
	\| LMDDx = ~~wosinophilic~~ vasculitis associated with a [[connective tissue disease]]		\| LMDDx = eosinophilic vasculitis associated with a [[connective tissue disease]]
	\| Stains =		\| Stains =
	\| IHC =		\| IHC =

Michael: +infobox

2016-11-25T11:56:47Z

+infobox

← Older revision		Revision as of 11:56, 25 November 2016
Line 1:		Line 1:
			{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image = Churg-Strauss_syndrome_-_high_mag.jpg
			\| Width =
			\| Caption = Eosinophilic granulomatosis with polyangiitis. [[H&E stain]].
			\| Synonyms =
			\| Micro = small vessel [[vasculitis]] with abundant eosinophils and [[granuloma]]s
			\| Subtypes =
			\| LMDDx = wosinophilic vasculitis associated with a [[connective tissue disease]]
			\| Stains =
			\| IHC =
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross =
			\| Grossing =
			\| Staging =
			\| Site = [[blood vessels]]
			\| Assdx = [[asthma]]
			\| Syndromes =
			\| Clinicalhx =
			\| Signs = fever
			\| Symptoms =
			\| Prevalence = rare
			\| Bloodwork =
			\| Rads =
			\| Endoscopy =
			\| Prognosis =
			\| Other =
			\| ClinDDx =
			\| Tx =
			}}
	'''Eosinophilic granulomatosis with polyangiitis''', previously known as '''Churg-Strauss syndrome''',<ref name=pmid26051917>{{Cite journal \| last1 = Stone \| first1 = JR. \| last2 = Bruneval \| first2 = P. \| last3 = Angelini \| first3 = A. \| last4 = Bartoloni \| first4 = G. \| last5 = Basso \| first5 = C. \| last6 = Batoroeva \| first6 = L. \| last7 = Buja \| first7 = LM. \| last8 = Butany \| first8 = J. \| last9 = d'Amati \| first9 = G. \| title = Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association for European Cardiovascular Pathology: I. Inflammatory diseases. \| journal = Cardiovasc Pathol \| volume = 24 \| issue = 5 \| pages = 267-78 \| month = \| year = \| doi = 10.1016/j.carpath.2015.05.001 \| PMID = 26051917 }}</ref> is a type of [[vasculitis]].		'''Eosinophilic granulomatosis with polyangiitis''', previously known as '''Churg-Strauss syndrome''',<ref name=pmid26051917>{{Cite journal \| last1 = Stone \| first1 = JR. \| last2 = Bruneval \| first2 = P. \| last3 = Angelini \| first3 = A. \| last4 = Bartoloni \| first4 = G. \| last5 = Basso \| first5 = C. \| last6 = Batoroeva \| first6 = L. \| last7 = Buja \| first7 = LM. \| last8 = Butany \| first8 = J. \| last9 = d'Amati \| first9 = G. \| title = Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association for European Cardiovascular Pathology: I. Inflammatory diseases. \| journal = Cardiovasc Pathol \| volume = 24 \| issue = 5 \| pages = 267-78 \| month = \| year = \| doi = 10.1016/j.carpath.2015.05.001 \| PMID = 26051917 }}</ref> is a type of [[vasculitis]].

Michael at 11:37, 25 November 2016

2016-11-25T11:37:12Z

← Older revision		Revision as of 11:37, 25 November 2016
Line 9:		Line 9:

	Notes:		Notes:
	*Similar to [[Granulomatosis with polyangiitis]] (Wegener's granulomatosis) -		*Similar to [[Granulomatosis with polyangiitis]] (Wegener's granulomatosis) - classically c-ANCA +ve, and ''microscopic polyangiitis''.<ref>URL: [http://emedicine.medscape.com/article/334024-overview http://emedicine.medscape.com/article/334024-overview]. Accessed on: 22 January 2011.</ref>
	classically c-ANCA +ve, and ''microscopic polyangiitis''.<ref>URL: [http://emedicine.medscape.com/article/334024-overview http://emedicine.medscape.com/article/334024-overview]. Accessed on: 22 January 2011.</ref>

	==Microscopic==		==Microscopic==

Michael: /* General */

2016-11-25T11:35:57Z

General

← Older revision		Revision as of 11:35, 25 November 2016
Line 9:		Line 9:

	Notes:		Notes:
	*Similar to ''[[Wegener's granulomatosis~~]]'' (~~classically c-ANCA +ve) and ''microscopic polyangiitis''.<ref>URL: [http://emedicine.medscape.com/article/334024-overview http://emedicine.medscape.com/article/334024-overview]. Accessed on: 22 January 2011.</ref>		*Similar to [[Granulomatosis with polyangiitis]] (Wegener's granulomatosis) -
			classically c-ANCA +ve, and ''microscopic polyangiitis''.<ref>URL: [http://emedicine.medscape.com/article/334024-overview http://emedicine.medscape.com/article/334024-overview]. Accessed on: 22 January 2011.</ref>

	==Microscopic==		==Microscopic==

Michael: clearn

2016-11-25T11:33:33Z

clearn

← Older revision		Revision as of 11:33, 25 November 2016
Line 1:		Line 1:
	'''Eosinophilic granulomatosis with polyangiitis''', previously known as '''Churg-Strauss syndrome''',<ref name=pmid26051917>{{Cite journal \| last1 = Stone \| first1 = JR. \| last2 = Bruneval \| first2 = P. \| last3 = Angelini \| first3 = A. \| last4 = Bartoloni \| first4 = G. \| last5 = Basso \| first5 = C. \| last6 = Batoroeva \| first6 = L. \| last7 = Buja \| first7 = LM. \| last8 = Butany \| first8 = J. \| last9 = d'Amati \| first9 = G. \| title = Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association for European Cardiovascular Pathology: I. Inflammatory diseases. \| journal = Cardiovasc Pathol \| volume = 24 \| issue = 5 \| pages = 267-78 \| month = \| year = \| doi = 10.1016/j.carpath.2015.05.001 \| PMID = 26051917 }}</ref> is a type of [[vasculitis]].		'''Eosinophilic granulomatosis with polyangiitis''', previously known as '''Churg-Strauss syndrome''',<ref name=pmid26051917>{{Cite journal \| last1 = Stone \| first1 = JR. \| last2 = Bruneval \| first2 = P. \| last3 = Angelini \| first3 = A. \| last4 = Bartoloni \| first4 = G. \| last5 = Basso \| first5 = C. \| last6 = Batoroeva \| first6 = L. \| last7 = Buja \| first7 = LM. \| last8 = Butany \| first8 = J. \| last9 = d'Amati \| first9 = G. \| title = Consensus statement on surgical pathology of the aorta from the Society for Cardiovascular Pathology and the Association for European Cardiovascular Pathology: I. Inflammatory diseases. \| journal = Cardiovasc Pathol \| volume = 24 \| issue = 5 \| pages = 267-78 \| month = \| year = \| doi = 10.1016/j.carpath.2015.05.001 \| PMID = 26051917 }}</ref> is a type of [[vasculitis]].

	~~It is also known as ''allergic granulomatous angiitis''.<ref name=emedicine333492>[http://emedicine.medscape.com/article/333492-overview http://emedicine.medscape.com/article/333492-overview]</ref>~~

	==General==		==General==