Gastrointestinal tract polyps - Revision history

Michael: /* Pseudoinvasion in colorectal adenomatous polyps */

2018-03-18T23:51:33Z

Pseudoinvasion in colorectal adenomatous polyps

← Older revision		Revision as of 23:51, 18 March 2018
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	*[[AKA]] ''pseudoinvasion''.		*[[AKA]] ''pseudoinvasion''.
	*[[AKA]] ''epithelial misplacement''.		*[[AKA]] ''epithelial misplacement''.
	~~===General===~~		{{Main\|Pseudoinvasion in colorectal adenomatous polyps}}
	*Mimic of invasion.
	*Pedunculated polyps.<ref>{{~~Cite journal \| last1 = Byun \| first1 = TJ. \| last2 = Han \| first2 = DS. \| last3 = Ahn \| first3 = SB.~~ \| ~~last4 = Cho \| first4 = HS. \| last5 = Eun \| first5 = CS. \| last6 = Jeon \| first6 = YC. \| last7 = Sohn \| first7 = JH. \| last8 = Oh \| first8 = YH. \| title =~~ Pseudoinvasion in an adenomatous polyp of the colon mimicking invasive colon cancer. \| journal = Gut Liver \| volume = 3 \| issue = 2 \| pages = 130-3 \| month = Jun \| year = 2009 \| doi = 10.5009/gnl.2009.3.2.130 \| PMID = 20431736 \| PMC = PMC2852693 \| URL = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852693/ }}</ref>
	*Left-sided lesions, esp. sigmoid colon.<ref name=Ref_Odze512>{{Ref Odze\|512}}</ref>

	~~===Microscopic===~~
	~~Features - classic:<ref name=pmid4540378>{{Cite journal \| last1 = Muto \| first1 = T. \| last2 = Bussey \| first2 = HJ. \| last3 = Morson \| first3 = BC. \| title = Pseudo-carcinomatous invasion in~~ adenomatous polyps of the colon and rectum. \| journal = J Clin Pathol \| volume = 26 \| issue = 1 \| pages = 25-31 \| month = Jan \| year = 1973 \| doi = \| PMID = 4540378 \| PMC = 477644 \| URL = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC477644/?tool=pubmed }}~~</ref>~~
	~~#Dysplastic glands surrounded by lamina propria.~~
	~~#Hemosiderin.~~
	~~#Lack of [[desmoplastic reaction]].~~
	*+/-Cystic spaces with rounded contours without cells floating in them.

	~~Memory device (classic features) ''LDH'':~~
	*'''L'''amina propria.
	*'''D'''esmoplasia lacking.
	*'''H'''emosiderin.

	~~DDx:~~
	*[[Gastrointestinal_tract_polyps#Colorectal_adenocarcinoma\|Colorectal adenocarcinoma]].

	~~===Sign out===~~
	~~Note:~~
	*The term ''pseudoinvasion'' may be confusing to clinicians.

	~~<pre>~~
	~~COLON POLYP, SIGMOID COLON AT 45 CM, EXCISION:~~
	~~- TUBULAR ADENOMA.~~
	~~-- NEGATIVE FOR HIGH-GRADE DYSPLASIA.~~
	~~- SUBMUCOSA PRESENT, NO EVIDENCE OF INVASION.~~
	~~- ABUNDANT HEMOSIDERIN-LADEN MACROPHAGES.~~
	~~</pre>~~

	~~====Alternate====~~
	~~<pre>~~
	~~POLYP, SIGMOID COLON, EXCISION:~~
	~~- LARGE TUBULAR ADENOMA.~~
	~~-- NEGATIVE FOR HIGH-GRADE DYSPLASIA.~~
	~~- SCANT BENIGN SUBMUCOSA.~~
	~~- DEEP HEMOSIDERIN-LADEN MACROPHAGES.~~
	~~</pre>~~

	==High-risk features in (colorectal) adenomatous polyps with carcinoma==		==High-risk features in (colorectal) adenomatous polyps with carcinoma==

Michael: /* Pseudoinvasion in colorectal adenomatous polyps */ weak

2018-03-18T23:47:04Z

Pseudoinvasion in colorectal adenomatous polyps: weak

← Older revision		Revision as of 23:47, 18 March 2018
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	==Pseudoinvasion in colorectal adenomatous polyps==		==Pseudoinvasion in colorectal adenomatous polyps==
	~~{{ Infobox external links~~
	~~\| Name = Pseudoinvasion in colorectal adenomatous polyps~~
	~~\| EHVSC = 10175~~
	~~\| pathprotocols =~~
	~~\| wikipedia =~~
	~~\| pathoutlines =~~
	}}
	*[[AKA]] ''pseudoinvasion''.		*[[AKA]] ''pseudoinvasion''.
	*[[AKA]] ''epithelial misplacement''.		*[[AKA]] ''epithelial misplacement''.

Michael: /* Pseudoinvasion in colorectal adenomatous polyps */ synonym

2018-03-18T23:46:45Z

Pseudoinvasion in colorectal adenomatous polyps: synonym

← Older revision		Revision as of 23:46, 18 March 2018
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	}}		}}
	*[[AKA]] ''pseudoinvasion''.		*[[AKA]] ''pseudoinvasion''.
			*[[AKA]] ''epithelial misplacement''.
	===General===		===General===
	*Mimic of invasion.		*Mimic of invasion.

Michael: /* High-risk features in (colorectal) adenomatous polyps with carcinoma */

2017-09-28T19:10:13Z

High-risk features in (colorectal) adenomatous polyps with carcinoma

← Older revision		Revision as of 19:10, 28 September 2017
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	Note:		Note:
	*‡Tumour budding, as per international consensus, is now assessed in field area of 0.785 mm<sup>2</sup>.<ref name=pmid28548122>{{Cite journal \| last1 = Lugli \| first1 = A. \| last2 = Kirsch \| first2 = R. \| last3 = Ajioka \| first3 = Y. \| last4 = Bosman \| first4 = F. \| last5 = Cathomas \| first5 = G. \| last6 = Dawson \| first6 = H. \| last7 = El Zimaity \| first7 = H. \| last8 = Fléjou \| first8 = JF. \| last9 = Hansen \| first9 = TP. \| title = Recommendations for reporting tumor budding in colorectal cancer based on the International Tumor Budding Consensus Conference (ITBCC) 2016. \| journal = Mod Pathol \| volume = 30 \| issue = 9 \| pages = 1299-1311 \| month = Sep \| year = 2017 \| doi = 10.1038/modpathol.2017.46 \| PMID = 28548122 }}</ref>		*‡Tumour budding as per international consensus is now assessed in field area of 0.785 mm<sup>2</sup>.<ref name=pmid28548122>{{Cite journal \| last1 = Lugli \| first1 = A. \| last2 = Kirsch \| first2 = R. \| last3 = Ajioka \| first3 = Y. \| last4 = Bosman \| first4 = F. \| last5 = Cathomas \| first5 = G. \| last6 = Dawson \| first6 = H. \| last7 = El Zimaity \| first7 = H. \| last8 = Fléjou \| first8 = JF. \| last9 = Hansen \| first9 = TP. \| title = Recommendations for reporting tumor budding in colorectal cancer based on the International Tumor Budding Consensus Conference (ITBCC) 2016. \| journal = Mod Pathol \| volume = 30 \| issue = 9 \| pages = 1299-1311 \| month = Sep \| year = 2017 \| doi = 10.1038/modpathol.2017.46 \| PMID = 28548122 }}</ref>

	==Traditional adenoma==		==Traditional adenoma==

Michael: /* High-risk features in (colorectal) adenomatous polyps with carcinoma */

2017-09-28T19:09:51Z

High-risk features in (colorectal) adenomatous polyps with carcinoma

← Older revision		Revision as of 19:09, 28 September 2017
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	#[[Lymphovascular invasion]].		#[[Lymphovascular invasion]].
	#High-grade [[tumour budding]].		#High-grade [[tumour budding]].
	#*Tumour bud = 1-4 cell(s); "high-grade budding" is >=10 tumour buds in a field of 0.385 mm<sup>2</sup>.<ref name=pmid11952856>{{Cite journal \| last1 = Ueno \| first1 = H. \| last2 = Murphy \| first2 = J. \| last3 = Jass \| first3 = JR. \| last4 = Mochizuki \| first4 = H. \| last5 = Talbot \| first5 = IC. \| title = Tumour 'budding' as an index to estimate the potential of aggressiveness in rectal cancer. \| journal = Histopathology \| volume = 40 \| issue = 2 \| pages = 127-32 \| month = Feb \| year = 2002 \| doi = \| PMID = 11952856 }}</ref>		#*Tumour bud = 1-4 cell(s); "high-grade budding" is >=10 tumour buds in a field of 0.385 mm<sup>2</sup>.<ref name=pmid11952856>{{Cite journal \| last1 = Ueno \| first1 = H. \| last2 = Murphy \| first2 = J. \| last3 = Jass \| first3 = JR. \| last4 = Mochizuki \| first4 = H. \| last5 = Talbot \| first5 = IC. \| title = Tumour 'budding' as an index to estimate the potential of aggressiveness in rectal cancer. \| journal = Histopathology \| volume = 40 \| issue = 2 \| pages = 127-32 \| month = Feb \| year = 2002 \| doi = \| PMID = 11952856 }}</ref>‡
	#**If the microscope has a 22 mm eye piece and...		#**If the microscope has a 22 mm eye piece and...
	#***A 20x objective, the field is approximately 0.950 mm<sup>2</sup> -- to match the buds/area -- it would be 24.68 buds/0.950 mm<sup>2</sup>.		#***A 20x objective, the field is approximately 0.950 mm<sup>2</sup> -- to match the buds/area -- it would be 24.68 buds/0.950 mm<sup>2</sup>.
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	If none of the above factors is present the risk of [[lymph node]] metastasis is < 1%. The presence of one risk factor increases the risk to ~20%. If multiple risk factors are present the chance of [[lymph node metastases]] is greater than 35%.<ref name=pmid15300569/>		If none of the above factors is present the risk of [[lymph node]] metastasis is < 1%. The presence of one risk factor increases the risk to ~20%. If multiple risk factors are present the chance of [[lymph node metastases]] is greater than 35%.<ref name=pmid15300569/>

			Note:
			*‡Tumour budding, as per international consensus, is now assessed in field area of 0.785 mm<sup>2</sup>.<ref name=pmid28548122>{{Cite journal \| last1 = Lugli \| first1 = A. \| last2 = Kirsch \| first2 = R. \| last3 = Ajioka \| first3 = Y. \| last4 = Bosman \| first4 = F. \| last5 = Cathomas \| first5 = G. \| last6 = Dawson \| first6 = H. \| last7 = El Zimaity \| first7 = H. \| last8 = Fléjou \| first8 = JF. \| last9 = Hansen \| first9 = TP. \| title = Recommendations for reporting tumor budding in colorectal cancer based on the International Tumor Budding Consensus Conference (ITBCC) 2016. \| journal = Mod Pathol \| volume = 30 \| issue = 9 \| pages = 1299-1311 \| month = Sep \| year = 2017 \| doi = 10.1038/modpathol.2017.46 \| PMID = 28548122 }}</ref>

	==Traditional adenoma==		==Traditional adenoma==

Michael: /* Sign out */

2016-07-10T18:30:35Z

Sign out

← Older revision		Revision as of 18:30, 10 July 2016
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	===Sign out===		===Sign out===
			Note:
			*The term ''pseudoinvasion'' may be confusing to clinicians.

	<pre>		<pre>
	COLON POLYP, SIGMOID COLON AT 45 CM, EXCISION:		COLON POLYP, SIGMOID COLON AT 45 CM, EXCISION:

Michael: /* See also */

2016-02-13T15:48:54Z

Michael: /* Ganglioneuroma */

2015-10-29T00:38:03Z

Ganglioneuroma

← Older revision		Revision as of 00:38, 29 October 2015
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	*Ganglion cells - '''key feature'''.		*Ganglion cells - '''key feature'''.
	**Large cells with a round nucleus and a prominent nucleolus.		**Large cells with a round nucleus and a prominent nucleolus.

			DDx:
			*[[Hyperplastic polyp with perineuromatous stroma]].

	====Images====		====Images====
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	Image:Ganglioneuroma_-_very_high_mag.jpg \| Ganglioneuroma - very high mag. (WC/Nephron)		Image:Ganglioneuroma_-_very_high_mag.jpg \| Ganglioneuroma - very high mag. (WC/Nephron)
	</gallery>		</gallery>

	==Inflammatory myoglandular polyp==		==Inflammatory myoglandular polyp==
	===General===		===General===

Michael: /* Normal */

2015-08-19T16:31:36Z

Normal

← Older revision		Revision as of 16:31, 19 August 2015
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	===Sign out===		===Sign out===
	====Normal====		====Normal====
			<pre>
			Cecum, Biopsy:
			- Colorectal-type mucosa within normal limits.
			</pre>

			<pre>
			Right Colon, Biopsy:
			- Colonic mucosa within normal limits.
			</pre>

			<pre>
			Transverse Colon, Biopsy:
			- Colonic mucosa within normal limits.
			</pre>

			<pre>
			Left Colon, Biopsy:
			- Colonic mucosa within normal limits.
			</pre>

			<pre>
			Rectum, Biopsy:
			- Colorectal mucosa within normal limits.
			</pre>

			=====Block letters=====
	<pre>		<pre>
	SIGMOID COLON, BIOPSY:		SIGMOID COLON, BIOPSY:

Michael: touch

2015-04-27T21:26:43Z

touch

← Older revision		Revision as of 21:26, 27 April 2015
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	[[Image:Polyp-2.jpeg\|thumb\|right\|Endoscopic image of a gastrointestinal polyp.]]		[[Image:Polyp-2.jpeg\|thumb\|right\|Endoscopic image of a gastrointestinal polyp.]]
	'''Gastrointestinal tract polyps''', also '''gastrointestinal polyps''' or '''GI polyps''', are the bread & butter of a GI pathologists workload. Some of 'em are benign... some pre-malignant... some malignant... some weird. Most GI polyps are from the intestine, i.e. intestinal polyps.		'''Gastrointestinal tract polyps''', also '''gastrointestinal polyps''' or '''GI polyps''', are the bread & butter of a GI pathologists workload. Some of 'em are benign... some pre-malignant... some malignant... some weird. Most GI polyps are from the intestine, i.e. intestinal polyps.

← Older revision		Revision as of 15:48, 13 February 2016
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	*[[Small bowel]].		*[[Small bowel]].
	*[[Colon]].		*[[Colon]].
			*[[Polypectomy]].

	=References=		=References=