Glassy cell carcinoma - Revision history

Michael at 02:40, 25 April 2014

2014-04-25T02:40:23Z

← Older revision		Revision as of 02:40, 25 April 2014
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	'''Glassy cell carcinoma''', abbreviated '''GCC''', is a rare [[malignancy]] of the [[uterine cervix]].		'''Glassy cell carcinoma''', abbreviated '''GCC''', is a rare [[malignancy]] of the [[uterine cervix]].

			It is considered to be a subtype of [[adenosquamous carcinoma of the uterine cervix]].
	==General==		==General==
	*Rare.		*Rare.

Michael: /* Microscopic */

2014-04-25T02:33:33Z

Microscopic

← Older revision		Revision as of 02:33, 25 April 2014
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	**Round/oval nucleus.		**Round/oval nucleus.
	**One or more prominent nucleoli.		**One or more prominent nucleoli.
	**Abundant finely vacuolated eosinophilic to amphophilic cytoplasm.		**Abundant finely vacuolated eosinophilic to amphophilic cytoplasm - looks "glassy".
	**Distinct cell borders.		**Distinct cell borders.
	*Inflammation - esp. eosinophils.<ref>URL: [http://www.webpathology.com/image.asp?n=2&Case=561 http://www.webpathology.com/image.asp?n=2&Case=561]. Accessed on: 4 September 2011.</ref>		*Inflammation - esp. eosinophils.<ref>URL: [http://www.webpathology.com/image.asp?n=2&Case=561 http://www.webpathology.com/image.asp?n=2&Case=561]. Accessed on: 4 September 2011.</ref>

Michael at 02:31, 25 April 2014

2014-04-25T02:31:43Z

← Older revision		Revision as of 02:31, 25 April 2014
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	\| Micro = epithelioid cells in sheets or cords with a round/oval nucleus, one or more prominent nucleoli, abundant finely vacuolated eosinophilic to amphophilic cytoplasm, distinct cell borders, inflammation - especially eosinophils		\| Micro = epithelioid cells in sheets or cords with a round/oval nucleus, one or more prominent nucleoli, abundant finely vacuolated eosinophilic to amphophilic cytoplasm, distinct cell borders, inflammation - especially eosinophils
	\| Subtypes =		\| Subtypes =
	\| LMDDx = [[~~Adenosquamous carcinoma\|~~adenosquamous carcinoma of the uterine cervix]], [[squamous carcinoma of the uterine cervix]]		\| LMDDx = [[adenosquamous carcinoma of the uterine cervix]], [[squamous carcinoma of the uterine cervix]]
	\| Stains = [[PAS stain]] +ve (plasma membrane)		\| Stains = [[PAS stain]] +ve (plasma membrane)
	\| IHC =		\| IHC =

Michael at 02:30, 25 April 2014

2014-04-25T02:30:24Z

← Older revision		Revision as of 02:30, 25 April 2014
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	{{ Infobox diagnosis		{{ Infobox diagnosis
	\| Name = {{PAGENAME}}		\| Name = {{PAGENAME}}
	\| Image = Glassy_cell_carcinoma_-~~_high_mag~~.jpg		\| Image = Glassy_cell_carcinoma_-_very_high_mag.jpg
	\| Width =		\| Width =
	\| Caption = Glassy cell carcinoma. [[H&E stain]].		\| Caption = Glassy cell carcinoma. [[H&E stain]].

Michael at 02:30, 25 April 2014

2014-04-25T02:30:04Z

← Older revision		Revision as of 02:30, 25 April 2014
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			{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image = Glassy_cell_carcinoma_-_high_mag.jpg
			\| Width =
			\| Caption = Glassy cell carcinoma. [[H&E stain]].
			\| Synonyms =
			\| Micro = epithelioid cells in sheets or cords with a round/oval nucleus, one or more prominent nucleoli, abundant finely vacuolated eosinophilic to amphophilic cytoplasm, distinct cell borders, inflammation - especially eosinophils
			\| Subtypes =
			\| LMDDx = [[Adenosquamous carcinoma\|adenosquamous carcinoma of the uterine cervix]], [[squamous carcinoma of the uterine cervix]]
			\| Stains = [[PAS stain]] +ve (plasma membrane)
			\| IHC =
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross =
			\| Grossing =
			\| Site = [[uterine cervix]]
			\| Assdx =
			\| Syndromes =
			\| Clinicalhx = rapid growth
			\| Signs =
			\| Symptoms =
			\| Prevalence = rare
			\| Bloodwork =
			\| Rads =
			\| Endoscopy =
			\| Prognosis = poor
			\| Other =
			\| ClinDDx = other [[uterine cervix\|cervical]] tumours
			\| Tx =
			}}
	'''Glassy cell carcinoma''', abbreviated '''GCC''', is a rare [[malignancy]] of the [[uterine cervix]].		'''Glassy cell carcinoma''', abbreviated '''GCC''', is a rare [[malignancy]] of the [[uterine cervix]].

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	==Microscopic==		==Microscopic==
	Features:<ref name=pmid11393075>{{Cite journal \| last1 = Reis-Filho \| first1 = JS. \| last2 = Fillus Neto \| first2 = J. \| last3 = Schonemann \| first3 = E. \| last4 = Sanderson \| first4 = A. \| last5 = Schmitt \| first5 = FC. \| title = Glassy cell carcinoma of the uterine cervix. Report of a case with cytohistologic and immunohistochemical study. \| journal = Acta Cytol \| volume = 45 \| issue = 3 \| pages = 407-10 \| month = \| year = \| doi = \| PMID = 11393075 }}</ref>		Features:<ref name=pmid11393075>{{Cite journal \| last1 = Reis-Filho \| first1 = JS. \| last2 = Fillus Neto \| first2 = J. \| last3 = Schonemann \| first3 = E. \| last4 = Sanderson \| first4 = A. \| last5 = Schmitt \| first5 = FC. \| title = Glassy cell carcinoma of the uterine cervix. Report of a case with cytohistologic and immunohistochemical study. \| journal = Acta Cytol \| volume = 45 \| issue = 3 \| pages = 407-10 \| month = \| year = \| doi = \| PMID = 11393075 }}</ref>
	*Epithelioid cells in sheets or cords.		*Epithelioid cells in sheets or cords with:
	*Round/oval nucleus.		**Round/oval nucleus.
	*One or more prominent nucleoli.		**One or more prominent nucleoli.
	*Abundant finely vacuolated eosinophilic to amphophilic cytoplasm.		**Abundant finely vacuolated eosinophilic to amphophilic cytoplasm.
	*Distinct cell borders.		**Distinct cell borders.
	*Inflammation - esp. eosinophils.<ref>URL: [http://www.webpathology.com/image.asp?n=2&Case=561 http://www.webpathology.com/image.asp?n=2&Case=561]. Accessed on: 4 September 2011.</ref>		*Inflammation - esp. eosinophils.<ref>URL: [http://www.webpathology.com/image.asp?n=2&Case=561 http://www.webpathology.com/image.asp?n=2&Case=561]. Accessed on: 4 September 2011.</ref>

Michael: split out

2014-04-25T02:24:23Z

split out

← Older revision		Revision as of 02:24, 25 April 2014
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	~~#redirect~~ [[~~Uterine_cervix#Glassy_cell_carcinoma~~]]		'''Glassy cell carcinoma''', abbreviated '''GCC''', is a rare [[malignancy]] of the [[uterine cervix]].

			==General==
			*Rare.
			*Rapid growth, poor prognosis.<ref name=pmid19527406>{{Cite journal \| last1 = Nasu \| first1 = K. \| last2 = Takai \| first2 = N. \| last3 = Narahara \| first3 = H. \| title = Multimodal treatment for glassy cell carcinoma of the uterine cervix. \| journal = J Obstet Gynaecol Res \| volume = 35 \| issue = 3 \| pages = 584-7 \| month = Jun \| year = 2009 \| doi = 10.1111/j.1447-0756.2008.00968.x \| PMID = 19527406 }}</ref>
			*Considered a subtype of [[adenosquamous carcinoma]].<ref name=pmid22384631>{{Cite journal \| last1 = Kosińiska-Kaczyńska \| first1 = K. \| last2 = Mazanowska \| first2 = N. \| last3 = Bomba-Opoń \| first3 = D. \| last4 = Horosz \| first4 = E. \| last5 = Marczewska \| first5 = M. \| last6 = Wielgoś \| first6 = M. \| title = Glassy cell carcinoma of the cervix--a case report with review of the literature. \| journal = Ginekol Pol \| volume = 82 \| issue = 12 \| pages = 936-9 \| month = Dec \| year = 2011 \| doi = \| PMID = 22384631 }}</ref>

			==Microscopic==
			Features:<ref name=pmid11393075>{{Cite journal \| last1 = Reis-Filho \| first1 = JS. \| last2 = Fillus Neto \| first2 = J. \| last3 = Schonemann \| first3 = E. \| last4 = Sanderson \| first4 = A. \| last5 = Schmitt \| first5 = FC. \| title = Glassy cell carcinoma of the uterine cervix. Report of a case with cytohistologic and immunohistochemical study. \| journal = Acta Cytol \| volume = 45 \| issue = 3 \| pages = 407-10 \| month = \| year = \| doi = \| PMID = 11393075 }}</ref>
			*Epithelioid cells in sheets or cords.
			*Round/oval nucleus.
			*One or more prominent nucleoli.
			*Abundant finely vacuolated eosinophilic to amphophilic cytoplasm.
			*Distinct cell borders.
			*Inflammation - esp. eosinophils.<ref>URL: [http://www.webpathology.com/image.asp?n=2&Case=561 http://www.webpathology.com/image.asp?n=2&Case=561]. Accessed on: 4 September 2011.</ref>

			DDx:
			*[[Adenosquamous carcinoma of the uterine cervix]].
			*[[Squamous carcinoma of the uterine cervix]].

			===Images===
			<gallery>
			Image:Glassy_cell_carcinoma_-_low_mag.jpg \| GCC - low mag. (WC)
			Image:Glassy_cell_carcinoma_-_intermed_mag.jpg \| GCC - intermed. mag. (WC)
			Image:Glassy_cell_carcinoma_-_high_mag.jpg \| GCC - high mag. (WC)
			Image:Glassy_cell_carcinoma_-_very_high_mag.jpg \| GCC - very high mag. (WC)
			</gallery>
			www:
			*[http://www.webpathology.com/image.asp?n=1&Case=561 GCC - low mag. (webpathology.com)].
			*[http://www.webpathology.com/image.asp?n=2&Case=561 GCC - high mag. (webpathology.com)].
			*[http://path.upmc.edu/cases/case100/dx.html GCC - several images (upmc.edu)].

			==Stains==
			*[[PAS stain]] - marks plasma membrane.<ref name=pmid15318016>{{Cite journal \| last1 = Deshpande \| first1 = AH. \| last2 = Kotwal \| first2 = MN. \| last3 = Bobhate \| first3 = SK. \| title = Glassy cell carcinoma of the uterine cervix a rare histology. Report of three cases with a review of the literature. \| journal = Indian J Cancer \| volume = 41 \| issue = 2 \| pages = 92-5 \| month = \| year = \| doi = \| PMID = 15318016 \| URL = http://www.indianjcancer.com/text.asp?2004/41/2/92/12353}}</ref>

			==See also==
			*[[Eosinophils]].
			*[[Uterine cervix]].

			==References==
			{{Reflist\|2}}

			[[Category:Diagnosis]]
			[[Category:Uterine cervix]]

Michael: redirect

2011-09-05T03:29:11Z

redirect

New page

#redirect [[Uterine_cervix#Glassy_cell_carcinoma]]