Gonadoblastoma - Revision history

Michael at 20:30, 15 July 2014

2014-07-15T20:30:58Z

← Older revision		Revision as of 20:30, 15 July 2014
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	\| Micro = immature germ cells (resembling Sertoli cells or granulosa cells),{{fact}} primitive germ cells resemble those of a [[dysgerminoma]], +/-calcification (very common), +/-eosinophilic basement membrane material between the (primitive) germ cells and support cells.		\| Micro = immature germ cells (resembling Sertoli cells or granulosa cells),{{fact}} primitive germ cells resemble those of a [[dysgerminoma]], +/-calcification (very common), +/-eosinophilic basement membrane material between the (primitive) germ cells and support cells.
	\| Subtypes =		\| Subtypes =
	\| LMDDx = [[dysgerminoma]]		\| LMDDx = [[dysgerminoma]], [[sex cord tumour with annular tubules]]
	\| Stains =		\| Stains =
	\| IHC =		\| IHC =
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	*+/-Eosinophilic basement membrane material between the (primitive) germ cells and support cells.<ref>URL: [http://www.flickr.com/photos/ckrishnan/3972432044/in/photostream/ http://www.flickr.com/photos/ckrishnan/3972432044/in/photostream/]. Accessed on: 11 September 2011.</ref>		*+/-Eosinophilic basement membrane material between the (primitive) germ cells and support cells.<ref>URL: [http://www.flickr.com/photos/ckrishnan/3972432044/in/photostream/ http://www.flickr.com/photos/ckrishnan/3972432044/in/photostream/]. Accessed on: 11 September 2011.</ref>

			DDx:
			*[[Sex cord tumour with annular tubules]].
			*[[Dysgerminoma]].
	===Images===		===Images===
	<gallery>		<gallery>

Michael: more

2013-07-13T23:33:45Z

← Older revision		Revision as of 23:33, 13 July 2013
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	[[Category:Diagnosis]]		[[Category:Diagnosis]]
			[[Category:Germ cell tumours]]

Michael: more

2013-07-13T23:32:52Z

← Older revision		Revision as of 23:32, 13 July 2013
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	\| Assdx =		\| Assdx =
	\| Syndromes =		\| Syndromes =
	\| Clinicalhx =		\| Clinicalhx = abnormal sexual development
	\| Signs =		\| Signs =
	\| Symptoms =		\| Symptoms =
	\| Prevalence =		\| Prevalence = very rare
	\| Bloodwork =		\| Bloodwork =
	\| Rads =		\| Rads =

Michael: /* Images */ more images

2013-07-13T23:32:02Z

Images: more images

← Older revision		Revision as of 23:32, 13 July 2013
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	===Images===		===Images===
	<gallery>		<gallery>
	Image:~~Gonadoblastoma_~~-~~_intermed_mag~~.jpg \| Gonadoblastoma - intermed. mag. (WC/Nephron)		Image:Gonadoblastoma - very low mag.jpg \| Gonadoblastoma - very low mag. (WC/Nephron)
	Image:~~Gonadoblastoma_~~-~~_b_~~-~~_high_mag~~.jpg \| Gonadoblastoma - high mag. (WC/Nephron)		Image:Gonadoblastoma - low mag.jpg \| Gonadoblastoma - low mag. (WC/Nephron)
			Image:Gonadoblastoma - intermed mag.jpg \| Gonadoblastoma - intermed mag. (WC/Nephron)
			Image:Gonadoblastoma - high mag.jpg \| Gonadoblastoma - high mag. (WC/Nephron)
			Image:Gonadoblastoma - b - high mag.jpg \| Gonadoblastoma - high mag. (WC/Nephron)
			Image:Gonadoblastoma - very high mag.jpg \| Gonadoblastoma - very high mag. (WC/Nephron)
	</gallery>		</gallery>
	www:		www:

Michael: tweka

2013-07-13T23:30:36Z

tweka

← Older revision		Revision as of 23:30, 13 July 2013
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	\| Width =		\| Width =
	\| Caption = Gondaloblastoma. [[H&E stain]].		\| Caption = Gondaloblastoma. [[H&E stain]].
	\| Micro = immature germ cells (resembling Sertoli cells or granulosa cells), primitive germ cells resemble those of a [[dysgerminoma]],		\| Micro = immature germ cells (resembling Sertoli cells or granulosa cells),{{fact}} primitive germ cells resemble those of a [[dysgerminoma]], +/-calcification (very common), +/-eosinophilic basement membrane material between the (primitive) germ cells and support cells.
	+/-calcification (very common), +/-eosinophilic basement membrane material between the (primitive) germ cells and support cells.
	\| Subtypes =		\| Subtypes =
	\| LMDDx = [[dysgerminoma]]		\| LMDDx = [[dysgerminoma]]
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	==Microscopic==		==Microscopic==
	Features:<ref name=Ref_PBoD1104>{{Ref PBoD\|1104}}</ref>		Features:<ref name=Ref_PBoD1104>{{Ref PBoD\|1104}}</ref>
	*Immature germ cells resembling Sertoli cells or granulosa cells.		*Immature germ cells resembling Sertoli cells or granulosa cells.{{fact}}
	**Sertoli cells = moderate cytoplasm in a trabecular or tubular architecture.		**Sertoli cells = moderate cytoplasm in a trabecular or tubular architecture.
	**Granulosa cells = form follicle-like structures.		**Granulosa cells = form follicle-like structures.

Michael: split out

2013-07-13T23:30:01Z

split out

← Older revision		Revision as of 23:30, 13 July 2013
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	~~#redirect~~ [[~~Germ_cell_tumours#~~Gonadoblastoma]]		{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image = Gonadoblastoma_-_b_-_high_mag.jpg
			\| Width =
			\| Caption = Gondaloblastoma. [[H&E stain]].
			\| Micro = immature germ cells (resembling Sertoli cells or granulosa cells), primitive germ cells resemble those of a [[dysgerminoma]],
			+/-calcification (very common), +/-eosinophilic basement membrane material between the (primitive) germ cells and support cells.
			\| Subtypes =
			\| LMDDx = [[dysgerminoma]]
			\| Stains =
			\| IHC =
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross =
			\| Grossing =
			\| Site = [[ovary]]
			\| Assdx =
			\| Syndromes =
			\| Clinicalhx =
			\| Signs =
			\| Symptoms =
			\| Prevalence =
			\| Bloodwork =
			\| Rads =
			\| Endoscopy =
			\| Prognosis =
			\| Other =
			\| ClinDDx =
			}}
			'''Gonadoblastoma''' is a rare [[germ cell tumour]] with sex cord elements.

			==General==
			*Associated with abnormal sexual development.
			*Often coexist with a [[dysgerminoma]].
			*A mixed tumour that consists of (1) primitive germ cells and (2) sex cord elements.

			==Gross==
			*+/-Cystic.

			==Microscopic==
			Features:<ref name=Ref_PBoD1104>{{Ref PBoD\|1104}}</ref>
			*Immature germ cells resembling Sertoli cells or granulosa cells.
			**Sertoli cells = moderate cytoplasm in a trabecular or tubular architecture.
			**Granulosa cells = form follicle-like structures.
			***May form nests.
			*Primitive germ cells resemble those of a [[dysgerminoma]].
			**Polygonal cells with a central nucleus, squared-off nuclear membrane and clear cytoplasm.
			*+/-Calcification (very common).
			*+/-Eosinophilic basement membrane material between the (primitive) germ cells and support cells.<ref>URL: [http://www.flickr.com/photos/ckrishnan/3972432044/in/photostream/ http://www.flickr.com/photos/ckrishnan/3972432044/in/photostream/]. Accessed on: 11 September 2011.</ref>

			===Images===
			<gallery>
			Image:Gonadoblastoma_-_intermed_mag.jpg \| Gonadoblastoma - intermed. mag. (WC/Nephron)
			Image:Gonadoblastoma_-_b_-_high_mag.jpg \| Gonadoblastoma - high mag. (WC/Nephron)
			</gallery>
			www:
			*[http://www.webpathology.com/image.asp?n=40&Case=532 Gonadoblastoma - low mag. (webpathology.com)].
			*[http://www.webpathology.com/image.asp?case=532&n=42 Gonadoblastoma - high mag. (webpathology.com)].
			*[http://www.webpathology.com/image.asp?case=532&n=44 Gonadoblastoma - high mag. (webpathology.com)].
			*[http://www.flickr.com/photos/ckrishnan/3972431774/in/photostream/ Gonadoblastoma - low mag. (flickr.com)].
			*[http://www.flickr.com/photos/ckrishnan/3972432404/in/photostream/ Gonadoblastoma - intermed. mag. (flickr.com)].
			*[http://www.flickr.com/photos/ckrishnan/3972432044/in/photostream/ Gonadoblastoma - high mag. (flickr.com)].
			*[http://path.upmc.edu/cases/case356.html Gonadoblastoma - several cases (upmc.edu)].

			==See also==
			*[[Germ cell tumours]].

			==References==
			{{Reflist\|2}}

	[[Category:Diagnosis]]		[[Category:Diagnosis]]

Michael: +cat.

2011-10-22T19:22:53Z

+cat.

← Older revision		Revision as of 19:22, 22 October 2011
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	#redirect [[Germ_cell_tumours#Gonadoblastoma]]		#redirect [[Germ_cell_tumours#Gonadoblastoma]]

			[[Category:Diagnosis]]

Michael: redirect to GCT article

2011-04-12T00:44:43Z

redirect to GCT article

New page

#redirect [[Germ_cell_tumours#Gonadoblastoma]]