Hyperplastic polyp - Revision history

Michael at 21:48, 19 September 2018

2018-09-19T21:48:27Z

← Older revision		Revision as of 21:48, 19 September 2018
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	\| Micro = serrated architecture at the surface without glandular abnormalities		\| Micro = serrated architecture at the surface without glandular abnormalities
	\| Subtypes = microvesicular serrated polyps (MVSPs), goblet cell serrated polyps (GCSPs)		\| Subtypes = microvesicular serrated polyps (MVSPs), goblet cell serrated polyps (GCSPs)
	\| LMDDx = [[sessile serrated adenoma]], [[normal colon]], other [[gastrointestinal polyps]]		\| LMDDx = [[sessile serrated adenoma]], [[normal colon]], [[hyperplastic polyp with perineuromatous stroma]], other [[gastrointestinal polyps]]
	\| Stains =		\| Stains =
	\| IHC = [[Chromogranin A]] +ve (increased scattered Chromogranin A-positive cells in relation to normal mucosa)		\| IHC = [[Chromogranin A]] +ve (increased scattered Chromogranin A-positive cells in relation to normal mucosa)
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	*[[Normal colon]].		*[[Normal colon]].
	*[[Colorectal xanthomatous polyp\|Xanthomatous polyp]] with hyperplastic features.<ref name=pmid14961968>{{Cite journal \| last1 = Nakasono \| first1 = M. \| last2 = Hirokawa \| first2 = M. \| last3 = Muguruma \| first3 = N. \| last4 = Okahisa \| first4 = T. \| last5 = Okamura \| first5 = S. \| last6 = Ito \| first6 = S. \| last7 = Miyamoto \| first7 = H. \| last8 = Wada \| first8 = S. \| last9 = Fukuda \| first9 = T. \| title = Colorectal xanthomas with polypoid lesion: report of 25 cases. \| journal = APMIS \| volume = 112 \| issue = 1 \| pages = 3-10 \| month = Jan \| year = 2004 \| doi = \| PMID = 14961968 }}</ref>		*[[Colorectal xanthomatous polyp\|Xanthomatous polyp]] with hyperplastic features.<ref name=pmid14961968>{{Cite journal \| last1 = Nakasono \| first1 = M. \| last2 = Hirokawa \| first2 = M. \| last3 = Muguruma \| first3 = N. \| last4 = Okahisa \| first4 = T. \| last5 = Okamura \| first5 = S. \| last6 = Ito \| first6 = S. \| last7 = Miyamoto \| first7 = H. \| last8 = Wada \| first8 = S. \| last9 = Fukuda \| first9 = T. \| title = Colorectal xanthomas with polypoid lesion: report of 25 cases. \| journal = APMIS \| volume = 112 \| issue = 1 \| pages = 3-10 \| month = Jan \| year = 2004 \| doi = \| PMID = 14961968 }}</ref>
			*[[Hyperplastic polyp with perineuromatous stroma]].

	===Images===		===Images===

Michael at 18:26, 25 April 2018

2018-04-25T18:26:54Z

← Older revision		Revision as of 18:26, 25 April 2018
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	\| LMDDx = [[sessile serrated adenoma]], [[normal colon]], other [[gastrointestinal polyps]]		\| LMDDx = [[sessile serrated adenoma]], [[normal colon]], other [[gastrointestinal polyps]]
	\| Stains =		\| Stains =
	\| IHC =		\| IHC = [[Chromogranin A]] +ve (increased scattered Chromogranin A-positive cells in relation to normal mucosa)
	\| EM =		\| EM =
	\| Molecular =		\| Molecular =

Michael: /* Sign out */

2018-04-25T18:26:10Z

Sign out

← Older revision		Revision as of 18:26, 25 April 2018
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	Notes:		Notes:
	*CIMP = CpG island methylation phenotype.		*CIMP = CpG island methylation phenotype.

			==IHC==
			*[[Chromogranin A]] increased scattered Chromogranin A-positive cells (in relation to normal colorectal mucosa).
			**[[Sessile serrated adenoma]] is completely negative for [[Chromogranin A]].

	==Sign out==		==Sign out==

Michael at 03:13, 29 October 2015

2015-10-29T03:13:51Z

← Older revision		Revision as of 03:13, 29 October 2015
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	\| Caption = Hyperplastic polyp. [[H&E stain]].		\| Caption = Hyperplastic polyp. [[H&E stain]].
	\| Micro = serrated architecture at the surface without glandular abnormalities		\| Micro = serrated architecture at the surface without glandular abnormalities
	\| Subtypes = microvesicular serrated polyps (MVSPs), goblet cell serrated polyps (GCSPs).		\| Subtypes = microvesicular serrated polyps (MVSPs), goblet cell serrated polyps (GCSPs)
	\| LMDDx = [[sessile serrated adenoma]], [[normal colon]], other [[gastrointestinal polyps]]		\| LMDDx = [[sessile serrated adenoma]], [[normal colon]], other [[gastrointestinal polyps]]
	\| Stains =		\| Stains =
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	*[[Gastrointestinal tract polyps]].		*[[Gastrointestinal tract polyps]].
	*[[Gastrointestinal pathology]].		*[[Gastrointestinal pathology]].
			*[[Hyperplastic polyp with perineuromatous stroma]].

	==References==		==References==

Michael: /* Subclassification */

2014-04-30T12:12:46Z

Subclassification

← Older revision		Revision as of 12:12, 30 April 2014
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	\| Goblet cell		\| Goblet cell
	\| superficial goblet cells, serration at <br>the surface		\| superficial goblet cells, serration at <br>the surface
	\| KRAS		\| [[KRAS mutation\|KRAS]]
	\| unknown; probably benign		\| unknown; probably benign
	\|}		\|}

Michael: /* Microscopic */

2014-03-20T13:17:46Z

Microscopic

← Older revision		Revision as of 13:17, 20 March 2014
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	*[[Sessile serrated adenoma]].		*[[Sessile serrated adenoma]].
	*[[Normal colon]].		*[[Normal colon]].
	*Xanthomatous polyp with hyperplastic features.<ref name=pmid14961968>{{Cite journal \| last1 = Nakasono \| first1 = M. \| last2 = Hirokawa \| first2 = M. \| last3 = Muguruma \| first3 = N. \| last4 = Okahisa \| first4 = T. \| last5 = Okamura \| first5 = S. \| last6 = Ito \| first6 = S. \| last7 = Miyamoto \| first7 = H. \| last8 = Wada \| first8 = S. \| last9 = Fukuda \| first9 = T. \| title = Colorectal xanthomas with polypoid lesion: report of 25 cases. \| journal = APMIS \| volume = 112 \| issue = 1 \| pages = 3-10 \| month = Jan \| year = 2004 \| doi = \| PMID = 14961968 }}</ref>		*[[Colorectal xanthomatous polyp\|Xanthomatous polyp]] with hyperplastic features.<ref name=pmid14961968>{{Cite journal \| last1 = Nakasono \| first1 = M. \| last2 = Hirokawa \| first2 = M. \| last3 = Muguruma \| first3 = N. \| last4 = Okahisa \| first4 = T. \| last5 = Okamura \| first5 = S. \| last6 = Ito \| first6 = S. \| last7 = Miyamoto \| first7 = H. \| last8 = Wada \| first8 = S. \| last9 = Fukuda \| first9 = T. \| title = Colorectal xanthomas with polypoid lesion: report of 25 cases. \| journal = APMIS \| volume = 112 \| issue = 1 \| pages = 3-10 \| month = Jan \| year = 2004 \| doi = \| PMID = 14961968 }}</ref>

	===Images===		===Images===

Michael: /* Microscopic */

2014-03-19T19:39:24Z

Microscopic

← Older revision		Revision as of 19:39, 19 March 2014
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	*[[Sessile serrated adenoma]].		*[[Sessile serrated adenoma]].
	*[[Normal colon]].		*[[Normal colon]].
			*Xanthomatous polyp with hyperplastic features.<ref name=pmid14961968>{{Cite journal \| last1 = Nakasono \| first1 = M. \| last2 = Hirokawa \| first2 = M. \| last3 = Muguruma \| first3 = N. \| last4 = Okahisa \| first4 = T. \| last5 = Okamura \| first5 = S. \| last6 = Ito \| first6 = S. \| last7 = Miyamoto \| first7 = H. \| last8 = Wada \| first8 = S. \| last9 = Fukuda \| first9 = T. \| title = Colorectal xanthomas with polypoid lesion: report of 25 cases. \| journal = APMIS \| volume = 112 \| issue = 1 \| pages = 3-10 \| month = Jan \| year = 2004 \| doi = \| PMID = 14961968 }}</ref>

	===Images===		===Images===

Michael: /* Sign out */ chg to polypectomy

2014-02-03T12:30:10Z

Sign out: chg to polypectomy

← Older revision		Revision as of 12:30, 3 February 2014
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	==Sign out==		==Sign out==
	<pre>		<pre>
	POLYP, RECTUM, ~~BIOPSY~~:		POLYP, RECTUM, POLYPECTOMY:
	- HYPERPLASTIC POLYP.		- HYPERPLASTIC POLYP.
	</pre>		</pre>

	<pre>		<pre>
	POLYP, SIGMOID COLON, ~~BIOPSY~~:		POLYP, SIGMOID COLON, POLYPECTOMY:
	- HYPERPLASTIC POLYP.		- HYPERPLASTIC POLYP.
	</pre>		</pre>

	<pre>		<pre>
	POLYP, DESCENDING COLON, ~~BIOPSY~~:		POLYP, DESCENDING COLON, POLYPECTOMY:
	- HYPERPLASTIC POLYP.		- HYPERPLASTIC POLYP.
	</pre>		</pre>

	<pre>		<pre>
	POLYP, TRANSVERSE COLON, ~~BIOPSY~~:		POLYP, TRANSVERSE COLON, POLYPECTOMY:
	- HYPERPLASTIC POLYP.		- HYPERPLASTIC POLYP.
	</pre>		</pre>

	<pre>		<pre>
	COLONIC POLYP, 35 CM, ~~BIOPSY~~:		COLONIC POLYP, 35 CM, POLYPECTOMY:
	- HYPERPLASTIC POLYP.		- HYPERPLASTIC POLYP.
	</pre>		</pre>
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	====Numerous hyperplastic polyps====		====Numerous hyperplastic polyps====
	<pre>		<pre>
	COLONIC POLYP(S), ~~BIOPSY~~:		COLONIC POLYP(S), POLYPECTOMY:
	- HYPERPLASTIC POLYP, SEE COMMENT.		- HYPERPLASTIC POLYP, SEE COMMENT.

Michael: /* Micro */

2014-01-27T14:14:35Z

Micro

← Older revision		Revision as of 14:14, 27 January 2014
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	pathologic change. The second fragment has the changes of a hyperplastic polyp		pathologic change. The second fragment has the changes of a hyperplastic polyp
	(superficial serrations, no serrations in the crypt base, no crypt base dilation).		(superficial serrations, no serrations in the crypt base, no crypt base dilation).

			====Minimal crypt base dilation====
			The sections show colonic-type mucosa with superficial serrations. Rare serrations are seen
			focally near the crypt base. Rare mild crypt base dilation is seen. No hockey stick-shaped
			glands are identified. No crypt branching is seen. No dysplasia is present.

	==See also==		==See also==

Michael: /* Microscopic */

2013-12-20T00:57:00Z

Microscopic

← Older revision		Revision as of 00:57, 20 December 2013
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	**No nuclear atypia; glands ''d''arker staining ''d''eep... ''l''ighter staining ''l''uminal.		**No nuclear atypia; glands ''d''arker staining ''d''eep... ''l''ighter staining ''l''uminal.
	**In the colon goblet cells should be present (as is usual).		**In the colon goblet cells should be present (as is usual).
	*Inflammation -- cryptitis or even crypt abscesses -- is considered to arise due to trauma.{{fact}}		*Inflammation -- [[cryptitis]] or even crypt abscesses -- is considered to arise due to trauma.{{fact}}
	**It is usually ''not'' reported.		**It is usually ''not'' reported.