Hypertrophic decidual vasculopathy - Revision history

Michael at 14:04, 27 November 2015

2015-11-27T14:04:09Z

← Older revision		Revision as of 14:04, 27 November 2015
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	\| Caption = Hypertrophic decidual vasculopathy. [[H&E stain]].		\| Caption = Hypertrophic decidual vasculopathy. [[H&E stain]].
	\| Synonyms = decidual vasculopathy		\| Synonyms = decidual vasculopathy
	\| Micro = ~~Mild~~ or moderate: perivascular inflammatory cells, +/-vascular thrombosis, smooth muscle hypertrophy, endothelial hyperplasia; severe: atherosis of maternal blood vessels, foamy macrophages within vascular wall, fibrinoid [[necrosis]] of vessel wall		\| Micro = mild or moderate: perivascular inflammatory cells, +/-vascular thrombosis, smooth muscle hypertrophy, endothelial hyperplasia; severe: atherosis of maternal blood vessels, foamy macrophages within vascular wall, fibrinoid [[necrosis]] of vessel wall
	\| Subtypes =		\| Subtypes =
	\| LMDDx =		\| LMDDx =

Michael at 14:03, 27 November 2015

2015-11-27T14:03:55Z

← Older revision		Revision as of 14:03, 27 November 2015
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			{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image = Hypertrophic decidual vasculopathy intermed mag.jpg
			\| Width =
			\| Caption = Hypertrophic decidual vasculopathy. [[H&E stain]].
			\| Synonyms = decidual vasculopathy
			\| Micro = Mild or moderate: perivascular inflammatory cells, +/-vascular thrombosis, smooth muscle hypertrophy, endothelial hyperplasia; severe: atherosis of maternal blood vessels, foamy macrophages within vascular wall, fibrinoid [[necrosis]] of vessel wall
			\| Subtypes =
			\| LMDDx =
			\| Stains =
			\| IHC =
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross =
			\| Grossing =
			\| Staging =
			\| Site = [[placenta]]
			\| Assdx = [[intrauterine growth restriction]]
			\| Syndromes =
			\| Clinicalhx =
			\| Signs = [[hypertension]]
			\| Symptoms =
			\| Prevalence = uncommon
			\| Bloodwork =
			\| Rads =
			\| Endoscopy =
			\| Prognosis =
			\| Other =
			\| ClinDDx = gestational hypertension, [[HELLP syndrome]]
			\| Tx = dependent on severity
			}}
	'''Hypertrophic decidual vasculopathy''', also known as '''decidual vasculopathy''', is a pathology of the placenta seen in the context of (gestational) [[hypertension]].		'''Hypertrophic decidual vasculopathy''', also known as '''decidual vasculopathy''', is a pathology of the placenta seen in the context of (gestational) [[hypertension]].

Michael: /* See also */

2015-02-13T07:16:36Z

Michael: split out

2015-02-13T07:13:33Z

split out

← Older revision		Revision as of 07:13, 13 February 2015
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	#~~redirect~~ [[Placenta~~#Hypertrophic_decidual_vasculopathy~~]]		'''Hypertrophic decidual vasculopathy''', also known as '''decidual vasculopathy''', is a pathology of the placenta seen in the context of (gestational) [[hypertension]].

			==General==
			*A change seen in [[hypertension]].
			*Seen in [[intrauterine growth restriction]] (IUGR).

			==Microscopic==
			Features:<ref name=pmid18641412>{{Cite journal \| last1 = Roberts \| first1 = DJ. \| last2 = Post \| first2 = MD. \| title = The placenta in pre-eclampsia and intrauterine growth restriction. \| journal = J Clin Pathol \| volume = 61 \| issue = 12 \| pages = 1254-60 \| month = Dec \| year = 2008 \| doi = 10.1136/jcp.2008.055236 \| PMID = 18641412 }}</ref>
			*Mild or moderate:
			*#Perivascular inflammatory cells.
			*#+/-Vascular [[thrombosis]].
			*#Smooth muscle hypertrophy.
			*#Endothelial hyperplasia.
			#Above two lead to narrowing of the decidual spiral arteries<ref>AFIP - Placental Pathology. P.122. ISBN: 1-881041-89-1. 2004.</ref> -- '''key feature'''.
			*Severe:<ref name=pmid18641412/>
			*#Atherosis of maternal blood vessels.
			#Foamy macrophages within vascular wall.
			*#[[Fibrinoid necrosis]] of vessel wall (amorphous eosinophilic material vessel wall).
			*Suggestive:<ref>{{Ref Placenta\|339}}</ref>
			**Decidual vasculitis - lymphocyte predominant without plasma cells.

			Note:
			*''Smooth muscle hypertrophy'' can also be understood as ''lack of physiological conversion of spiral arteries of the uterus''.<ref name=pmid12848643>{{Cite journal \| last1 = Naicker \| first1 = T. \| last2 = Khedun \| first2 = SM. \| last3 = Moodley \| first3 = J. \| last4 = Pijnenborg \| first4 = R. \| title = Quantitative analysis of trophoblast invasion in preeclampsia. \| journal = Acta Obstet Gynecol Scand \| volume = 82 \| issue = 8 \| pages = 722-9 \| month = Aug \| year = 2003 \| doi = \| PMID = 12848643 }}</ref>

			===Images===
			<gallery>
			Image:Hypertrophic_decidual_vasculopathy_intermed_mag.jpg \| HDV - intermed. mag. (WC)
			Image:Hypertrophic_decidual_vasculopathy_low_mag.jpg \| HDV - low mag. (WC)
			</gallery>
			www:
			*[http://path.upmc.edu/cases/case75/images/micro2.jpg Atherosis (upmc.edu)].<ref>URL: [http://path.upmc.edu/cases/case75.html http://path.upmc.edu/cases/case75.html]. Accessed on: 2 January 2012.</ref>
			*[http://www.surgpath4u.com/caseviewer.php?case_no=490 Decidual vasculopathy (surgpath4u.com)].
			*[http://www.brown.edu/Courses/Digital_Path/systemic_path/cardio/decidualvasculopathy.html Decidual vasculopathy (brown.edu)].

			==Sign out==
			<pre>
			PLACENTA, UMBILICAL CORD AND FETAL MEMBRANES, CESAREAN SECTION:
			- DECIDUAL VASCULOPATHY.
			- PLACENTA SMALL FOR GESTATIONAL AGE (222 GRAMS).
			- PLACENTAL DISC WITH EARLY THIRD TRIMESTER VILLI WITH:
			-- MULTIPLE PLACENTAL INFARCTS.
			-- PERIVILLOUS FIBRIN DEPOSITION.
			- THREE VESSEL UMBILICAL CORD WITHIN NORMAL LIMITS.
			- FETAL MEMBRANES WITHIN NORMAL LIMITS.

			COMMENT:
			The 10th percentile placental mass (pre-fixation) for 32 weeks and 6
			days is approximately 247 grams.
			</pre>

			===Suggestive of decidual vasculopathy===
			<pre>
			PLACENTA, UMBILICAL CORD AND FETAL MEMBRANES, CESAREAN SECTION:
			- CHANGES SUGGESTIVE OF DECIDUAL VASCULOPATHY (DECIDUAL VASCULITIS).
			- PLACENTAL DISC WITH EARLY THIRD TRIMESTER VILLI AND A PLACENTAL INFARCT
			(2.5 CM IN MAXIMAL DIMENSION).
			- THREE VESSEL UMBILICAL CORD WITHIN NORMAL LIMITS.
			- FETAL MEMBRANES WITHIN NORMAL LIMITS.
			</pre>

			==See also==
			*[[Placenta]].

			==References==
			{{Reflist\|2}}

	[[Category:Diagnosis]]		[[Category:Diagnosis]]
			[[Category:Placenta]]

Michael: +cat.

2011-10-18T04:30:37Z

+cat.

← Older revision		Revision as of 04:30, 18 October 2011
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	#redirect [[Placenta#Hypertrophic_decidual_vasculopathy]]		#redirect [[Placenta#Hypertrophic_decidual_vasculopathy]]

			[[Category:Diagnosis]]

Michael: redirect

2011-07-27T14:20:58Z

redirect

New page

#redirect [[Placenta#Hypertrophic_decidual_vasculopathy]]

← Older revision		Revision as of 07:16, 13 February 2015
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	==See also==		==See also==
	*[[Placenta]].		*[[Placenta]].
			*[[HELLP syndrome]].

	==References==		==References==