Intestinal metaplasia of the stomach - Revision history

Michael at 12:56, 3 May 2016

2016-05-03T12:56:29Z

← Older revision		Revision as of 12:56, 3 May 2016
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	\| Micro = goblet cells with foveolar epithelium		\| Micro = goblet cells with foveolar epithelium
	\| Subtypes =		\| Subtypes =
	\| LMDDx = contaminant from the [[duodenum]], [[gastric dysplasia]], [[gastric carcinoma]]		\| LMDDx = contaminant from the [[duodenum]], [[gastric dysplasia]], [[gastric carcinoma]], [[gastric heterotopia of the duodenum]]
	\| Stains = alcian blue/PAS +ve		\| Stains = alcian blue/PAS +ve
	\| IHC = CDX2 +ve		\| IHC = CDX2 +ve

Michael: /* Microscopic */

2016-05-03T12:56:14Z

Microscopic

← Older revision		Revision as of 12:56, 3 May 2016
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	*[[Normal duodenum\|Normal small bowel mucosa]] - no foveolar epithelium present, possibly a contaminant from a concurrent duodenal biopsy.		*[[Normal duodenum\|Normal small bowel mucosa]] - no foveolar epithelium present, possibly a contaminant from a concurrent duodenal biopsy.
	*[[Gastric dysplasia]], intestinal type.		*[[Gastric dysplasia]], intestinal type.
			*[[Gastric heterotopia of the duodenum]].

	===Images===		===Images===

Michael: /* IHC */ fix ref

2016-02-13T12:55:15Z

IHC: fix ref

← Older revision		Revision as of 12:55, 13 February 2016
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	</gallery>		</gallery>
	==IHC==		==IHC==
	*CDX2 +ve (-ve in normal stomach).<ref name=pmid12477745>{{Cite journal \| last1 = Walker \| first1 = MM. \| title = Is intestinal metaplasia of the stomach reversible? \| journal = Gut \| volume = 52 \| issue = 1 \| pages = 1-4 \| month = Jan \| year = 2003 \| doi = \| PMID = 12477745 \| PMC = 1773527		*CDX2 +ve (-ve in normal stomach).<ref name=pmid12477745/>
	~~}}<~~/~~ref~~>
	**Strong assoc. with ''[[Helicobacter gastritis]]'' as well as IM.<ref name=pmid12047325>{{Cite journal \| last1 = Satoh \| first1 = K. \| last2 = Mutoh \| first2 = H. \| last3 = Eda \| first3 = A. \| last4 = Yanaka \| first4 = I. \| last5 = Osawa \| first5 = H. \| last6 = Honda \| first6 = S. \| last7 = Kawata \| first7 = H. \| last8 = Kihira \| first8 = K. \| last9 = Sugano \| first9 = K. \| title = Aberrant expression of CDX2 in the gastric mucosa with and without intestinal metaplasia: effect of eradication of Helicobacter pylori. \| journal = Helicobacter \| volume = 7 \| issue = 3 \| pages = 192-8 \| month = Jun \| year = 2002 \| doi = \| PMID = 12047325 }}</ref>		**Strong assoc. with ''[[Helicobacter gastritis]]'' as well as IM.<ref name=pmid12047325>{{Cite journal \| last1 = Satoh \| first1 = K. \| last2 = Mutoh \| first2 = H. \| last3 = Eda \| first3 = A. \| last4 = Yanaka \| first4 = I. \| last5 = Osawa \| first5 = H. \| last6 = Honda \| first6 = S. \| last7 = Kawata \| first7 = H. \| last8 = Kihira \| first8 = K. \| last9 = Sugano \| first9 = K. \| title = Aberrant expression of CDX2 in the gastric mucosa with and without intestinal metaplasia: effect of eradication of Helicobacter pylori. \| journal = Helicobacter \| volume = 7 \| issue = 3 \| pages = 192-8 \| month = Jun \| year = 2002 \| doi = \| PMID = 12047325 }}</ref>

Michael: /* Focal */

2015-11-09T14:15:37Z

Focal

← Older revision		Revision as of 14:15, 9 November 2015
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	==Sign out==		==Sign out==
	===Focal===		===Focal===
			<pre>
			Stomach, Antrum, Biopsy:
			- Antral-type gastric mucosa with intestinal metaplasia (focal) and
			moderate chronic inactive inflammation.
			- NEGATIVE for Helicobacter-like organisms.
			- NEGATIVE for dysplasia and NEGATIVE for malignancy.
			</pre>

			====Block letters====
	<pre>		<pre>
	STOMACH, BIOPSY:		STOMACH, BIOPSY:

Michael: touch

2015-04-19T05:05:14Z

touch

← Older revision		Revision as of 05:05, 19 April 2015
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	{{ Infobox diagnosis		{{ Infobox diagnosis
	\| Name = {{PAGENAME}}		\| Name = {{PAGENAME}}
	\| Image = Stomach with intestinal metaplasia -- intermed mag.jpg		\| Image = Stomach with intestinal metaplasia -- intermed mag.jpg
	\| Width =		\| Width =
	\| Caption = Intestinal metaplasia of the stomach. [[H&E stain]].		\| Caption = Intestinal metaplasia of the stomach. [[H&E stain]].

Michael: touch

2015-04-05T13:01:15Z

touch

← Older revision		Revision as of 13:01, 5 April 2015
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	{{ Infobox diagnosis		{{ Infobox diagnosis
	\| Name = {{PAGENAME}}		\| Name = {{PAGENAME}}
	\| Image = Stomach with intestinal metaplasia -- intermed mag.jpg		\| Image = Stomach with intestinal metaplasia -- intermed mag.jpg
	\| Width =		\| Width =
	\| Caption = Intestinal metaplasia of the stomach. [[H&E stain]].		\| Caption = Intestinal metaplasia of the stomach. [[H&E stain]].

Michael: /* Images */ rm crappy im

2014-01-17T23:49:31Z

Images: rm crappy im

← Older revision		Revision as of 23:49, 17 January 2014
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	Image: Stomach with intestinal metaplasia -- intermed mag.jpg \| Stomach IM - intermed. mag. (WC)		Image: Stomach with intestinal metaplasia -- intermed mag.jpg \| Stomach IM - intermed. mag. (WC)
	Image: Stomach with intestinal metaplasia -- high mag.jpg \| Stomach IM - high mag. (WC)		Image: Stomach with intestinal metaplasia -- high mag.jpg \| Stomach IM - high mag. (WC)
	~~</gallery>~~
	~~<gallery>~~
	~~Image:Gastric_adenocarcinoma.jpg \| Intestinal metaplasia in the stomach - crappy quality. (WC)~~
	</gallery>		</gallery>

Michael: more images

2014-01-17T23:49:02Z

more images

← Older revision		Revision as of 23:49, 17 January 2014
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	{{ Infobox diagnosis		{{ Infobox diagnosis
	\| Name = {{PAGENAME}}		\| Name = {{PAGENAME}}
	\| Image = ~~Gastric~~ intestinal metaplasia.jpg		\| Image = Stomach with intestinal metaplasia -- intermed mag.jpg
	\| Width =		\| Width =
	\| Caption = Intestinal metaplasia of the stomach. [[H&E stain]].		\| Caption = Intestinal metaplasia of the stomach. [[H&E stain]].
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	===Images===		===Images===
			<gallery>
			Image: Stomach with intestinal metaplasia -- intermed mag.jpg \| Stomach IM - intermed. mag. (WC)
			Image: Stomach with intestinal metaplasia -- high mag.jpg \| Stomach IM - high mag. (WC)
			</gallery>
	<gallery>		<gallery>
	Image:Gastric_adenocarcinoma.jpg \| Intestinal metaplasia in the stomach - crappy quality. (WC)		Image:Gastric_adenocarcinoma.jpg \| Intestinal metaplasia in the stomach - crappy quality. (WC)

Michael: /* Microscopic */

2013-12-20T19:28:32Z

Microscopic

← Older revision		Revision as of 19:28, 20 December 2013
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	DDx:		DDx:
	*[[Normal duodenum\|Normal small bowel mucosa]] - no foveolar epithelium present.		*[[Normal duodenum\|Normal small bowel mucosa]] - no foveolar epithelium present, possibly a contaminant from a concurrent duodenal biopsy.
	*[[Gastric dysplasia]], intestinal type.		*[[Gastric dysplasia]], intestinal type.

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	Image:Gastric_adenocarcinoma.jpg \| Intestinal metaplasia in the stomach - crappy quality. (WC)		Image:Gastric_adenocarcinoma.jpg \| Intestinal metaplasia in the stomach - crappy quality. (WC)
	</gallery>		</gallery>

	==Stains==		==Stains==
	*Alcian blue (pH 2.5)/PAS +ve.<ref name=pmid14736279>{{Cite journal \| last1 = Rivera-Hueto \| first1 = F. \| last2 = Lag-Asturiano \| first2 = E. \| last3 = Utrilla-Alcolea \| first3 = JC. \| last4 = Herrerías-Gutiérrez \| first4 = JM. \| title = Advanced gastric carcinoma with a complete intestinal metaplasia phenotype associated with early intestinal-type carcinoma. \| journal = Arch Pathol Lab Med \| volume = 128 \| issue = 2 \| pages = 218-21 \| month = Feb \| year = 2004 \| doi = 10.1043/1543-2165(2004)128218:AGCWAC2.0.CO;2 \| PMID = 14736279 }}</ref>		*Alcian blue (pH 2.5)/PAS +ve.<ref name=pmid14736279>{{Cite journal \| last1 = Rivera-Hueto \| first1 = F. \| last2 = Lag-Asturiano \| first2 = E. \| last3 = Utrilla-Alcolea \| first3 = JC. \| last4 = Herrerías-Gutiérrez \| first4 = JM. \| title = Advanced gastric carcinoma with a complete intestinal metaplasia phenotype associated with early intestinal-type carcinoma. \| journal = Arch Pathol Lab Med \| volume = 128 \| issue = 2 \| pages = 218-21 \| month = Feb \| year = 2004 \| doi = 10.1043/1543-2165(2004)128218:AGCWAC2.0.CO;2 \| PMID = 14736279 }}</ref>

Michael: /* Focal */

2013-08-08T14:32:40Z

Focal

← Older revision		Revision as of 14:32, 8 August 2013
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	<pre>		<pre>
	STOMACH, BIOPSY:		STOMACH, BIOPSY:
	- BODY-TYPE MUCOSA WITH INTESTINAL METAPLASIA, FOCAL.		- BODY-TYPE GASTRIC MUCOSA WITH INTESTINAL METAPLASIA, FOCAL.
	- MINIMAL CHRONIC GASTRITIS (BODY OF STOMACH).		- MINIMAL CHRONIC GASTRITIS (BODY OF STOMACH).
	- NEGATIVE FOR HELICOBACTER-LIKE ORGANISMS.		- NEGATIVE FOR HELICOBACTER-LIKE ORGANISMS.
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	<pre>		<pre>
	STOMACH, BIOPSY:		STOMACH, BIOPSY:
	- ANTRAL-TYPE MUCOSA WITH FOCAL INTESTINAL METAPLASIA AND MILD CHRONIC		- ANTRAL-TYPE GASTRIC MUCOSA WITH FOCAL INTESTINAL METAPLASIA AND MILD CHRONIC
	INACTIVE INFLAMMATION.		INACTIVE INFLAMMATION.
	- NEGATIVE FOR HELICOBACTER-LIKE ORGANISMS.		- NEGATIVE FOR HELICOBACTER-LIKE ORGANISMS.