Intestinal spirochetosis - Revision history

Michael at 19:37, 22 February 2024

2024-02-22T19:37:54Z

← Older revision		Revision as of 19:37, 22 February 2024
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	==Gross==		==Gross==
	*Typically normal appearance.		*Typically normal appearance.

			Note:
	*Anatomical distribution in large intestine varies - may be absent in rectum.<ref name=pmid25540866>{{cite journal \|authors=Walker MM, Talley NJ, Inganäs L, Engstrand L, Jones MP, Nyhlin H, Agréus L, Kjellstrom L, Öst Å, Andreasson A \|title=Colonic spirochetosis is associated with colonic eosinophilia and irritable bowel syndrome in a general population in Sweden \|journal=Hum Pathol \|volume=46 \|issue=2 \|pages=277–83 \|date=February 2015 \|pmid=25540866 \|doi=10.1016/j.humpath.2014.10.026 \|url=}}</ref>		*Anatomical distribution in large intestine varies - may be absent in rectum.<ref name=pmid25540866>{{cite journal \|authors=Walker MM, Talley NJ, Inganäs L, Engstrand L, Jones MP, Nyhlin H, Agréus L, Kjellstrom L, Öst Å, Andreasson A \|title=Colonic spirochetosis is associated with colonic eosinophilia and irritable bowel syndrome in a general population in Sweden \|journal=Hum Pathol \|volume=46 \|issue=2 \|pages=277–83 \|date=February 2015 \|pmid=25540866 \|doi=10.1016/j.humpath.2014.10.026 \|url=}}</ref>

Michael at 19:28, 22 February 2024

2024-02-22T19:28:41Z

← Older revision		Revision as of 19:28, 22 February 2024
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	==Gross==		==Gross==
	*Typically normal appearance.		*Typically normal appearance.
	*Anatomical distribution in ~~colon~~ varies - may be absent in rectum.<ref>{{cite journal \|authors=Walker MM, Talley NJ, Inganäs L, Engstrand L, Jones MP, Nyhlin H, Agréus L, Kjellstrom L, Öst Å, Andreasson A \|title=Colonic spirochetosis is associated with colonic eosinophilia and irritable bowel syndrome in a general population in Sweden \|journal=Hum Pathol \|volume=46 \|issue=2 \|pages=277–83 \|date=February 2015 \|pmid=25540866 \|doi=10.1016/j.humpath.2014.10.026 \|url=}}</ref>		*Anatomical distribution in large intestine varies - may be absent in rectum.<ref name=pmid25540866>{{cite journal \|authors=Walker MM, Talley NJ, Inganäs L, Engstrand L, Jones MP, Nyhlin H, Agréus L, Kjellstrom L, Öst Å, Andreasson A \|title=Colonic spirochetosis is associated with colonic eosinophilia and irritable bowel syndrome in a general population in Sweden \|journal=Hum Pathol \|volume=46 \|issue=2 \|pages=277–83 \|date=February 2015 \|pmid=25540866 \|doi=10.1016/j.humpath.2014.10.026 \|url=}}</ref>

	==Microscopic==		==Microscopic==

Michael at 19:27, 22 February 2024

2024-02-22T19:27:48Z

← Older revision		Revision as of 19:27, 22 February 2024
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	\| Molecular =		\| Molecular =
	\| IF =		\| IF =
	\| Gross =		\| Gross =
	\| Grossing =		\| Grossing =
	\| Site = intestine - [[colon]]		\| Site = intestine - [[colon]]
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	\| Bloodwork =		\| Bloodwork =
	\| Rads =		\| Rads =
	\| Endoscopy =		\| Endoscopy = often normal
	\| Prognosis = benign		\| Prognosis = benign
	\| Other =		\| Other =
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	Treatment:<ref name=pmid17914949>{{cite journal \|author=Calderaro A, Bommezzadri S, Gorrini C, ''et al.'' \|title=Infective colitis associated with human intestinal spirochetosis \|journal=J. Gastroenterol. Hepatol. \|volume=22 \|issue=11 \|pages=1772–9 \|year=2007 \|month=November \|pmid=17914949 \|doi=10.1111/j.1440-1746.2006.04606.x \|url=}}</ref>		Treatment:<ref name=pmid17914949>{{cite journal \|author=Calderaro A, Bommezzadri S, Gorrini C, ''et al.'' \|title=Infective colitis associated with human intestinal spirochetosis \|journal=J. Gastroenterol. Hepatol. \|volume=22 \|issue=11 \|pages=1772–9 \|year=2007 \|month=November \|pmid=17914949 \|doi=10.1111/j.1440-1746.2006.04606.x \|url=}}</ref>
	*Metronidazole.		*Metronidazole.

			==Gross==
			*Typically normal appearance.
			*Anatomical distribution in colon varies - may be absent in rectum.<ref>{{cite journal \|authors=Walker MM, Talley NJ, Inganäs L, Engstrand L, Jones MP, Nyhlin H, Agréus L, Kjellstrom L, Öst Å, Andreasson A \|title=Colonic spirochetosis is associated with colonic eosinophilia and irritable bowel syndrome in a general population in Sweden \|journal=Hum Pathol \|volume=46 \|issue=2 \|pages=277–83 \|date=February 2015 \|pmid=25540866 \|doi=10.1016/j.humpath.2014.10.026 \|url=}}</ref>

	==Microscopic==		==Microscopic==

Michael: /* Special stains */

2017-10-23T19:34:03Z

Special stains

← Older revision		Revision as of 19:34, 23 October 2017
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	===Images===		===Images===
	*[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830567/figure/F3/ Spirochetes shown with a Warthin-Starry stain (nih.gov)].<ref name=pmid20200654>{{Cite journal \| last1 = Tsinganou \| first1 = E. \| last2 = Gebbers \| first2 = JO. \| title = Human intestinal spirochetosis--a review. \| journal = Ger Med Sci \| volume = 8 \| issue = \| pages = Doc01 \| month = Jan \| year = 2010 \| doi = 10.3205/000090 \| PMID = 20200654 }}</ref>		*[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830567/figure/F3/ Spirochetes shown with a Warthin-Starry stain (nih.gov)].<ref name=pmid20200654>{{Cite journal \| last1 = Tsinganou \| first1 = E. \| last2 = Gebbers \| first2 = JO. \| title = Human intestinal spirochetosis--a review. \| journal = Ger Med Sci \| volume = 8 \| issue = \| pages = Doc01 \| month = Jan \| year = 2010 \| doi = 10.3205/000090 \| PMID = 20200654 }}</ref>

			==Sign out==
			<pre>
			Rectum, Biopsy:
			- Colonic-type mucosa with spirochetes, otherwise within normal limits.

			Comment:
			The presence of spirochetes was confirmed with a Warthin-Starry stain.
			</pre>

	==See also==		==See also==

Michael: /* Images */

2017-10-19T18:20:18Z

Images

← Older revision		Revision as of 18:20, 19 October 2017
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	===Images===		===Images===
	*[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830567/figure/F3/		*[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830567/figure/F3/ Spirochetes shown with a Warthin-Starry stain (nih.gov)].<ref name=pmid20200654>{{Cite journal \| last1 = Tsinganou \| first1 = E. \| last2 = Gebbers \| first2 = JO. \| title = Human intestinal spirochetosis--a review. \| journal = Ger Med Sci \| volume = 8 \| issue = \| pages = Doc01 \| month = Jan \| year = 2010 \| doi = 10.3205/000090 \| PMID = 20200654 }}</ref>
	Spirochetes shown with a Warthin-Starry stain (nih.gov)].<ref name=pmid20200654>{{Cite journal \| last1 = Tsinganou \| first1 = E. \| last2 = Gebbers \| first2 = JO. \| title = Human intestinal spirochetosis--a review. \| journal = Ger Med Sci \| volume = 8 \| issue = \| pages = Doc01 \| month = Jan \| year = 2010 \| doi = 10.3205/000090 \| PMID = 20200654 }}</ref>

	==See also==		==See also==

Michael: /* Special stains */

2017-10-19T18:20:00Z

Special stains

← Older revision		Revision as of 18:20, 19 October 2017
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	==Special stains==		==Special stains==
	*Silver stains highlight 'em (e.g. [[Warthin-Starry stain]]).		*Silver stains highlight 'em (e.g. [[Warthin-Starry stain]]).

			===Images===
			*[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830567/figure/F3/
			Spirochetes shown with a Warthin-Starry stain (nih.gov)].<ref name=pmid20200654>{{Cite journal \| last1 = Tsinganou \| first1 = E. \| last2 = Gebbers \| first2 = JO. \| title = Human intestinal spirochetosis--a review. \| journal = Ger Med Sci \| volume = 8 \| issue = \| pages = Doc01 \| month = Jan \| year = 2010 \| doi = 10.3205/000090 \| PMID = 20200654 }}</ref>

	==See also==		==See also==

Michael: +infobox

2014-01-13T03:09:47Z

+infobox

← Older revision		Revision as of 03:09, 13 January 2014
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			{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image = Intestinal_spirochetosis_-_cropped_-_very_high_mag.jpg
			\| Width =
			\| Caption = Intestinal spirochetosis. [[H&E stain]].
			\| Synonyms =
			\| Micro = hyperchromatic fuzz on luminal aspect of epithelial cells - at brush border; spirochetes
			\| Subtypes =
			\| LMDDx =
			\| Stains = silver stains, e.g. [[Warthin-Starry stain]]
			\| IHC =
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross =
			\| Grossing =
			\| Site = intestine - [[colon]]
			\| Assdx =
			\| Syndromes =
			\| Clinicalhx =
			\| Signs = watery diarrhea +/-blood per rectum
			\| Symptoms = abdominal pain
			\| Prevalence = uncommon
			\| Bloodwork =
			\| Rads =
			\| Endoscopy =
			\| Prognosis = benign
			\| Other =
			\| ClinDDx = other causes of diarrhea
			\| Tx = antibiotics
			}}
	'''Intestinal spirochetosis''', also known as '''intestinal spirochetes''', in an uncommon intestinal infection.		'''Intestinal spirochetosis''', also known as '''intestinal spirochetes''', in an uncommon intestinal infection.

Michael: split-out

2014-01-13T03:06:12Z

split-out

← Older revision		Revision as of 03:06, 13 January 2014
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	~~#redirect~~ [[Colon~~#Intestinal_spirochetosis~~]]		'''Intestinal spirochetosis''', also known as '''intestinal spirochetes''', in an uncommon intestinal infection.

			It is usually in the [[colon]]; thus, also known as '''colonic spirochetes''' and '''colonic spirochetosis'''.

			==General==
			*Caused by spirochetes<ref name=pmid14718105>{{cite journal \|author=Amat Villegas I, Borobio Aguilar E, Beloqui Perez R, de Llano Varela P, Oquiñena Legaz S, Martínez-Peñuela Virseda JM \|title=[Colonic spirochetes: an infrequent cause of adult diarrhea] \|language=Spanish; Castilian \|journal=Gastroenterol Hepatol \|volume=27 \|issue=1 \|pages=21–3 \|year=2004 \|month=January \|pmid=14718105 \|doi= \|url=}}</ref><ref name=jhasim>URL: [http://www.jhasim.com/files/articlefiles/pdf/XASIM_Master_6_5_May_Vignette.pdf http://www.jhasim.com/files/articlefiles/pdf/XASIM_Master_6_5_May_Vignette.pdf]. Accessed on: 25 April 2011.</ref> - specifically ''Brachyspira piloicoli''<ref name=pmid19141744>{{Cite journal \| last1 = Margawani \| first1 = KR. \| last2 = Robertson \| first2 = ID. \| last3 = Hampson \| first3 = DJ. \| title = Isolation of the anaerobic intestinal spirochaete Brachyspira pilosicoli from long-term residents and Indonesian visitors to Perth, Western Australia. \| journal = J Med Microbiol \| volume = 58 \| issue = Pt 2 \| pages = 248-52 \| month = Feb \| year = 2009 \| doi = 10.1099/jmm.0.004770-0 \| PMID = 19141744 \| url = http://ukpmc.ac.uk/abstract/MED/19141744/abstract/MED/19141744?ukpmc_extredirect=http://dx.doi.org/10.1099/jmm.0.004770-0 }}</ref> (previously ''Serpulina pilosicoli''<ref>URL: [http://www.cdc.gov/ncidod/eid/vol12no05/05-1180.htm http://www.cdc.gov/ncidod/eid/vol12no05/05-1180.htm]. Accessed on: 28 June 2011.</ref>) and ''Brachyspira aalborgi''.
			*Very rare cause of diarrhea, associated with male homosexual behaviour.

			Symptoms:<ref name=jhasim>URL: [http://www.jhasim.com/files/articlefiles/pdf/XASIM_Master_6_5_May_Vignette.pdf http://www.jhasim.com/files/articlefiles/pdf/XASIM_Master_6_5_May_Vignette.pdf]. Accessed on: 25 April 2011.</ref>
			*Watery diarrhea, abdominal pain, +/-blood per rectum.

			Treatment:<ref name=pmid17914949>{{cite journal \|author=Calderaro A, Bommezzadri S, Gorrini C, ''et al.'' \|title=Infective colitis associated with human intestinal spirochetosis \|journal=J. Gastroenterol. Hepatol. \|volume=22 \|issue=11 \|pages=1772–9 \|year=2007 \|month=November \|pmid=17914949 \|doi=10.1111/j.1440-1746.2006.04606.x \|url=}}</ref>
			*Metronidazole.

			==Microscopic==
			Features:
			*Hyperchromatic fuzz on luminal aspect of epithelial cells; at brush border.

			DDx:
			*Normal colon.
			*[[Infectious colitis]] without a distinctive morphology.

			===Images===
			<gallery>
			Image:Intestinal_spirochetosis_-_cropped_-_very_high_mag.jpg \| Intestinal spirochetes - cropped - very high mag. (WC/Nephron)
			Image:Intestinal_spirochetosis_-_very_high_mag.jpg \| Intestinal spirochetes - very high mag. (WC/Nephron)
			Image:Intestinal_spirochetosis_-_intermed_mag.jpg \| Intestinal spirochetes - intermed. mag. (WC/Nephron)
			</gallery>
			www:
			*[http://path.upmc.edu/cases/case391.html Intestinal spirochetosis & CMV colitis - several images (upmc.edu)].
			==Special stains==
			*Silver stains highlight 'em (e.g. [[Warthin-Starry stain]]).

			==See also==
			*[[Colon]].

			==References==
			{{Reflist\|2}}

	[[Category:Diagnosis]]		[[Category:Diagnosis]]
			[[Category:Colon]]

Michael: +cat.

2011-10-22T23:41:43Z

+cat.

← Older revision		Revision as of 23:41, 22 October 2011
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	#redirect [[Colon#Intestinal_spirochetosis]]		#redirect [[Colon#Intestinal_spirochetosis]]

			[[Category:Diagnosis]]

Michael: chg redirect

2011-04-26T12:46:28Z

chg redirect

← Older revision		Revision as of 12:46, 26 April 2011
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	#redirect [[Colon#~~Colonic_spirochetosis~~]]		#redirect [[Colon#Intestinal_spirochetosis]]