Invasive lobular carcinoma - Revision history

Michael: /* IHC */

2021-12-20T19:26:28Z

IHC

← Older revision		Revision as of 19:26, 20 December 2021
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	Others:		Others:
	*CK20 -ve.		*CK20 -ve.
			*Beta-catenin -ve/+ve (~46% completely negative<ref name=pmid11237489>{{cite journal \|authors=Karayiannakis AJ, Nakopoulou L, Gakiopoulou H, Keramopoulos A, Davaris PS, Pignatelli M \|title=Expression patterns of beta-catenin in in situ and invasive breast cancer \|journal=Eur J Surg Oncol \|volume=27 \|issue=1 \|pages=31–6 \|date=February 2001 \|pmid=11237489 \|doi=10.1053/ejso.1999.1017 \|url=}}</ref>).

	==See also==		==See also==

Michael at 05:36, 23 January 2017

2017-01-23T05:36:52Z

← Older revision		Revision as of 05:36, 23 January 2017
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	\| LMDDx = [[invasive ductal carcinoma of the breast]] with lobular features, poorly differentiated carcinoma, [[LCIS]]		\| LMDDx = [[invasive ductal carcinoma of the breast]] with lobular features, poorly differentiated carcinoma, [[LCIS]]
	\| Stains =		\| Stains =
	\| IHC = E-cadherin -ve, usu. ER and PR +ve, HER2 -ve, CK7 +ve		\| IHC = [[E-cadherin]] -ve, usu. ER and PR +ve, HER2 -ve, [[CK7]] +ve
	\| EM =		\| EM =
	\| Molecular =		\| Molecular =
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	==IHC==		==IHC==
	Features:		Features:
	*E-cadherin -ve.		*[[E-cadherin]] -ve.
	*ER and PR +ve.		*ER and PR +ve.
	*HER2 -ve.		*HER2 -ve.

Michael at 11:35, 8 September 2016

2016-09-08T11:35:50Z

← Older revision		Revision as of 11:35, 8 September 2016
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	\| IF =		\| IF =
	\| Gross =		\| Gross =
	\| Grossing = [[~~mastectomy~~ grossing]]		\| Grossing = [[breast grossing]]
	\| Staging = [[breast cancer staging]]		\| Staging = [[breast cancer staging]]
	\| Site = [[breast]] - see ''[[invasive breast cancer]]''		\| Site = [[breast]] - see ''[[invasive breast cancer]]''

Michael at 04:11, 1 May 2016

2016-05-01T04:11:38Z

← Older revision		Revision as of 04:11, 1 May 2016
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	\| IF =		\| IF =
	\| Gross =		\| Gross =
	\| Grossing =		\| Grossing = [[mastectomy grossing]]
			\| Staging = [[breast cancer staging]]
	\| Site = [[breast]] - see ''[[invasive breast cancer]]''		\| Site = [[breast]] - see ''[[invasive breast cancer]]''
	\| Assdx =		\| Assdx =

Michael at 18:39, 19 March 2015

2015-03-19T18:39:36Z

← Older revision		Revision as of 18:39, 19 March 2015
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	*Poorly differentiated carcinoma.		*Poorly differentiated carcinoma.
	*[[LCIS]].		*[[LCIS]].
			*[[Malignant melanoma]].
	~~===Images===~~
	~~<gallery>~~
	~~Image:Lobular_carcinoma_-_low_mag.jpg \| Lobular carcinoma - low mag. (WC/Nephron)~~
	~~Image:Lobular_carcinoma_-_high_mag.jpg \| Lobular carcinoma - high mag. (WC/Nephron)~~
	~~Image:Lobular_carcinoma_-_high_mag.jpg \| Lobular carcinoma - very high mag. (WC/Nephron)~~
	~~</gallery>~~

	~~More~~ [[~~WC]~~] ~~images:~~
	*[http://commons.wikimedia.org/wiki/File:Breast_invasive_lobular_carcinoma_%281%29.jpg Lobular carcinoma - 1 (WC)].
	*[http://commons.wikimedia.org/wiki/File:Breast_invasive_lobular_carcinoma_%282%29.jpg Lobular carcinoma - 2 (WC)].

	===Subclassification===		===Subclassification===
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	Note:		Note:
	*Some pathologist grade lobular carcinoma like other types and avoid the term "pleomorphic lobular carcinoma."<ref>MUA. Jan 22, 2009.</ref>		*Some pathologist grade lobular carcinoma like other types and avoid the term "pleomorphic lobular carcinoma."<ref>MUA. Jan 22, 2009.</ref>

			Other variants:
			*Histiocytoid.<ref name=pmid21398688>{{Cite journal \| last1 = Tan \| first1 = PH. \| last2 = Harada \| first2 = O. \| last3 = Thike \| first3 = AA. \| last4 = Tse \| first4 = GM. \| title = Histiocytoid breast carcinoma: an enigmatic lobular entity. \| journal = J Clin Pathol \| volume = 64 \| issue = 8 \| pages = 654-9 \| month = Aug \| year = 2011 \| doi = 10.1136/jcp.2011.088930 \| PMID = 21398688 }}</ref>

			===Images===
			<gallery>
			Image:Lobular_carcinoma_-_low_mag.jpg \| Lobular carcinoma - low mag. (WC/Nephron)
			Image:Lobular_carcinoma_-_high_mag.jpg \| Lobular carcinoma - high mag. (WC/Nephron)
			Image:Lobular_carcinoma_-_high_mag.jpg \| Lobular carcinoma - very high mag. (WC/Nephron)
			</gallery>
			<gallery>
			Image:Breast_invasive_lobular_carcinoma_%281%29.jpg \| Lobular carcinoma - 1 (WC)
			Image:Breast_invasive_lobular_carcinoma_%282%29.jpg \| Lobular carcinoma - 2 (WC)
			</gallery>

	==IHC==		==IHC==

Michael at 04:34, 9 March 2014

2014-03-09T04:34:53Z

← Older revision		Revision as of 04:34, 9 March 2014
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	\| Site = [[breast]] - see ''[[invasive breast cancer]]''		\| Site = [[breast]] - see ''[[invasive breast cancer]]''
	\| Assdx =		\| Assdx =
	\| Syndromes = hereditary diffuse gastric cancer ~~syndrome~~		\| Syndromes = [[hereditary diffuse gastric cancer]]
	\| Clinicalhx =		\| Clinicalhx =
	\| Signs =		\| Signs =

Michael at 10:48, 14 February 2014

2014-02-14T10:48:18Z

← Older revision		Revision as of 10:48, 14 February 2014
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	\| LMDDx = [[invasive ductal carcinoma of the breast]] with lobular features, poorly differentiated carcinoma, [[LCIS]]		\| LMDDx = [[invasive ductal carcinoma of the breast]] with lobular features, poorly differentiated carcinoma, [[LCIS]]
	\| Stains =		\| Stains =
	\| IHC = usu. ER and PR +ve, HER2 -ve, CK7 +ve		\| IHC = E-cadherin -ve, usu. ER and PR +ve, HER2 -ve, CK7 +ve
	\| EM =		\| EM =
	\| Molecular =		\| Molecular =
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	Note:		Note:
	*Some pathologist grade lobular carcinoma like other types and avoid the term "pleomorphic lobular carcinoma."<ref>MUA. Jan 22, 2009.</ref>		*Some pathologist grade lobular carcinoma like other types and avoid the term "pleomorphic lobular carcinoma."<ref>MUA. Jan 22, 2009.</ref>

			==IHC==
			Features:
			*E-cadherin -ve.
			*ER and PR +ve.
			*HER2 -ve.
			*CK7 +ve.

			Others:
			*CK20 -ve.

	==See also==		==See also==

Michael: /* See also */

2014-02-14T10:47:17Z

Michael at 10:46, 14 February 2014

2014-02-14T10:46:37Z

← Older revision		Revision as of 10:46, 14 February 2014
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	\| Site = [[breast]] - see ''[[invasive breast cancer]]''		\| Site = [[breast]] - see ''[[invasive breast cancer]]''
	\| Assdx =		\| Assdx =
	\| Syndromes =		\| Syndromes = hereditary diffuse gastric cancer syndrome
	\| Clinicalhx =		\| Clinicalhx =
	\| Signs =		\| Signs =

Michael at 10:45, 14 February 2014

2014-02-14T10:45:18Z

← Older revision		Revision as of 10:45, 14 February 2014
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			{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image = Lobular_carcinoma_-_high_mag.jpg
			\| Width =
			\| Caption = Lobular carcinoma. [[H&E stain]].
			\| Synonyms =
			\| Micro =
			\| Subtypes =
			\| LMDDx = [[invasive ductal carcinoma of the breast]] with lobular features, poorly differentiated carcinoma, [[LCIS]]
			\| Stains =
			\| IHC = usu. ER and PR +ve, HER2 -ve, CK7 +ve
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross =
			\| Grossing =
			\| Site = [[breast]] - see ''[[invasive breast cancer]]''
			\| Assdx =
			\| Syndromes =
			\| Clinicalhx =
			\| Signs =
			\| Symptoms =
			\| Prevalence = relatively common
			\| Bloodwork =
			\| Rads =
			\| Endoscopy =
			\| Prognosis =
			\| Other =
			\| ClinDDx = other breast tumours
			\| Tx =
			}}
	'''Invasive lobular carcinoma''', abbreviated '''ILC''', is the second most common form of [[Invasive breast cancer]].		'''Invasive lobular carcinoma''', abbreviated '''ILC''', is the second most common form of [[Invasive breast cancer]].

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	*Commonly have low grade nuclear features.		*Commonly have low grade nuclear features.

			DDx:
	*[[Invasive ductal carcinoma of the breast]] with lobular features.		*[[Invasive ductal carcinoma of the breast]] with lobular features.
	*Poorly differentiated carcinoma.		*Poorly differentiated carcinoma.
			*[[LCIS]].

	===Images===		===Images===

← Older revision		Revision as of 10:47, 14 February 2014
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	==See also==		==See also==
	*[[Invasive breast cancer]].		*[[Invasive breast cancer]].
			*[[Signet ring cell carcinoma]].

	==References==		==References==