Kaposi sarcoma - Revision history

Michael at 17:43, 12 December 2021

2021-12-12T17:43:34Z

← Older revision		Revision as of 17:43, 12 December 2021
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	\| LMDDx = [[angiosarcoma]], [[Masson's hemangioma]] (''intravascular papillary endothelial hyperplasia''), benign lymphangioendothelioma		\| LMDDx = [[angiosarcoma]], [[Masson's hemangioma]] (''intravascular papillary endothelial hyperplasia''), benign lymphangioendothelioma
	\| Stains =		\| Stains =
	\| IHC = HHV-8 +ve, CD31 +ve, CD34 +ve		\| IHC = [[HHV-8]] +ve, CD31 +ve, CD34 +ve
	\| EM =		\| EM =
	\| Molecular =		\| Molecular =

Michael: move location of ","

2014-08-03T15:35:36Z

move location of ","

← Older revision		Revision as of 15:35, 3 August 2014
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	\| LMDDx = [[angiosarcoma]], [[Masson's hemangioma]] (''intravascular papillary endothelial hyperplasia''), benign lymphangioendothelioma		\| LMDDx = [[angiosarcoma]], [[Masson's hemangioma]] (''intravascular papillary endothelial hyperplasia''), benign lymphangioendothelioma
	\| Stains =		\| Stains =
	\| IHC = HHV-8 +ve, CD31 +ve ,CD34 +ve		\| IHC = HHV-8 +ve, CD31 +ve, CD34 +ve
	\| EM =		\| EM =
	\| Molecular =		\| Molecular =

Sarah at 11:18, 3 August 2014

2014-08-03T11:18:29Z

← Older revision		Revision as of 11:18, 3 August 2014
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	*D2-40 +ve.		*D2-40 +ve.
	*Ki-67 >10%.<ref name=pmid17210517>{{cite journal \|author=Wada DA, Perkins SL, Tripp S, Coffin CM, Florell SR \|title=Human herpesvirus 8 and iron staining are useful in differentiating Kaposi sarcoma from interstitial granuloma annulare \|journal=Am. J. Clin. Pathol. \|volume=127 \|issue=2 \|pages=263–70 \|year=2007 \|month=February \|pmid=17210517 \|doi=10.1309/GMH9CENH4909AWVB \|url=}}</ref>		*Ki-67 >10%.<ref name=pmid17210517>{{cite journal \|author=Wada DA, Perkins SL, Tripp S, Coffin CM, Florell SR \|title=Human herpesvirus 8 and iron staining are useful in differentiating Kaposi sarcoma from interstitial granuloma annulare \|journal=Am. J. Clin. Pathol. \|volume=127 \|issue=2 \|pages=263–70 \|year=2007 \|month=February \|pmid=17210517 \|doi=10.1309/GMH9CENH4909AWVB \|url=}}</ref>
			*ERG +ve. <ref name=pmid21317715>{{cite journal \|author=Miettinen M1, Wang ZF, Paetau A, Tan SH, Dobi A, Srivastava S, Sesterhenn I. \|title=ERG transcription factor as an immunohistochemical marker for vascular endothelial tumors and prostatic carcinoma. \|journal=Am J Surg Pathol. 2011 Mar;35(3):432-41. \|volume=35\|issue=3 \|pages=432-41 \|year=2011 \|month=march \|pmid=21317715 \|doi: 10.1097/PAS.0b013e318206b67b\|url=http://www.ncbi.nlm.nih.gov/pubmed/21317715}}</ref>
	==See also==		==See also==
	*[[Vascular tumours]].		*[[Vascular tumours]].

Michael: /* Stains */

2014-02-02T01:07:56Z

Stains

← Older revision		Revision as of 01:07, 2 February 2014
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	==Stains==		==Stains==
	*PAS +ve -- hyaline globules.		*PAS +ve -- hyaline globules.
			*[[Hale's colloidal iron stain]] +ve.<ref name=pmid17210517>{{cite journal \|author=Wada DA, Perkins SL, Tripp S, Coffin CM, Florell SR \|title=Human herpesvirus 8 and iron staining are useful in differentiating Kaposi sarcoma from interstitial granuloma annulare \|journal=Am. J. Clin. Pathol. \|volume=127 \|issue=2 \|pages=263–70 \|year=2007 \|month=February \|pmid=17210517 \|doi=10.1309/GMH9CENH4909AWVB \|url=}}</ref>

	==IHC==		==IHC==

Michael: /* IHC */

2014-02-02T01:07:30Z

IHC

← Older revision		Revision as of 01:07, 2 February 2014
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	*[[HHV-8]] +ve.		*[[HHV-8]] +ve.
	*D2-40 +ve.		*D2-40 +ve.
			*Ki-67 >10%.<ref name=pmid17210517>{{cite journal \|author=Wada DA, Perkins SL, Tripp S, Coffin CM, Florell SR \|title=Human herpesvirus 8 and iron staining are useful in differentiating Kaposi sarcoma from interstitial granuloma annulare \|journal=Am. J. Clin. Pathol. \|volume=127 \|issue=2 \|pages=263–70 \|year=2007 \|month=February \|pmid=17210517 \|doi=10.1309/GMH9CENH4909AWVB \|url=}}</ref>

	==See also==		==See also==

Michael at 01:00, 2 February 2014

2014-02-02T01:00:22Z

← Older revision		Revision as of 01:00, 2 February 2014
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	*Benign lymphangioendothelioma.<ref>{{Cite journal \| last1 = Guillou \| first1 = L. \| last2 = Fletcher \| first2 = CD. \| title = Benign lymphangioendothelioma (acquired progressive lymphangioma): a lesion not to be confused with well-differentiated angiosarcoma and patch stage Kaposi's sarcoma: clinicopathologic analysis of a series. \| journal = Am J Surg Pathol \| volume = 24 \| issue = 8 \| pages = 1047-57 \| month = Aug \| year = 2000 \| doi = \| PMID = 10935645 }}</ref>		*Benign lymphangioendothelioma.<ref>{{Cite journal \| last1 = Guillou \| first1 = L. \| last2 = Fletcher \| first2 = CD. \| title = Benign lymphangioendothelioma (acquired progressive lymphangioma): a lesion not to be confused with well-differentiated angiosarcoma and patch stage Kaposi's sarcoma: clinicopathologic analysis of a series. \| journal = Am J Surg Pathol \| volume = 24 \| issue = 8 \| pages = 1047-57 \| month = Aug \| year = 2000 \| doi = \| PMID = 10935645 }}</ref>
	**Histologically very similar.<ref>URL: [http://path.upmc.edu/cases/case134/dx.html http://path.upmc.edu/cases/case134/dx.html]. Accessed on: 5 January 2012.</ref>		**Histologically very similar.<ref>URL: [http://path.upmc.edu/cases/case134/dx.html http://path.upmc.edu/cases/case134/dx.html]. Accessed on: 5 January 2012.</ref>
	*[[Cavernous hemangioma]].<ref name=pmid24187557>~~PMID~~ 24187557</ref>		*[[Cavernous hemangioma]].<ref name=pmid24187557>{{cite journal \|author=Onak Kandemir N, Barut F, Doğan Gün B, Solak Tekin N, Hallaç Keser S, Oğuz Özdamar S \|title=Cavernous hemangioma-like kaposi sarcoma: histomorphologic features and differential diagnosis \|journal=Case Rep Med \|volume=2013 \|issue= \|pages=959812 \|year=2013 \|pmid=24187557 \|pmc=3800618 \|doi=10.1155/2013/959812 \|url=}}</ref>

	===Images===		===Images===
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	==IHC==		==IHC==
			Features:<ref name=pmid24187557/>
	*CD31 +ve.		*CD31 +ve.
	*CD34 +ve.		*CD34 +ve.
	*[[HHV-8]] +ve.		*[[HHV-8]] +ve.
			*D2-40 +ve.

	==See also==		==See also==

Michael: /* Microscopic */

2014-02-02T00:54:16Z

Microscopic

← Older revision		Revision as of 00:54, 2 February 2014
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	*Benign lymphangioendothelioma.<ref>{{Cite journal \| last1 = Guillou \| first1 = L. \| last2 = Fletcher \| first2 = CD. \| title = Benign lymphangioendothelioma (acquired progressive lymphangioma): a lesion not to be confused with well-differentiated angiosarcoma and patch stage Kaposi's sarcoma: clinicopathologic analysis of a series. \| journal = Am J Surg Pathol \| volume = 24 \| issue = 8 \| pages = 1047-57 \| month = Aug \| year = 2000 \| doi = \| PMID = 10935645 }}</ref>		*Benign lymphangioendothelioma.<ref>{{Cite journal \| last1 = Guillou \| first1 = L. \| last2 = Fletcher \| first2 = CD. \| title = Benign lymphangioendothelioma (acquired progressive lymphangioma): a lesion not to be confused with well-differentiated angiosarcoma and patch stage Kaposi's sarcoma: clinicopathologic analysis of a series. \| journal = Am J Surg Pathol \| volume = 24 \| issue = 8 \| pages = 1047-57 \| month = Aug \| year = 2000 \| doi = \| PMID = 10935645 }}</ref>
	**Histologically very similar.<ref>URL: [http://path.upmc.edu/cases/case134/dx.html http://path.upmc.edu/cases/case134/dx.html]. Accessed on: 5 January 2012.</ref>		**Histologically very similar.<ref>URL: [http://path.upmc.edu/cases/case134/dx.html http://path.upmc.edu/cases/case134/dx.html]. Accessed on: 5 January 2012.</ref>
	*[[~~Caverous~~ hemangioma]].<ref name=pmid24187557>PMID 24187557</ref>		*[[Cavernous hemangioma]].<ref name=pmid24187557>PMID 24187557</ref>

	===Images===		===Images===

Michael: /* Microscopic */

2014-02-02T00:53:54Z

Microscopic

← Older revision		Revision as of 00:53, 2 February 2014
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	*Benign lymphangioendothelioma.<ref>{{Cite journal \| last1 = Guillou \| first1 = L. \| last2 = Fletcher \| first2 = CD. \| title = Benign lymphangioendothelioma (acquired progressive lymphangioma): a lesion not to be confused with well-differentiated angiosarcoma and patch stage Kaposi's sarcoma: clinicopathologic analysis of a series. \| journal = Am J Surg Pathol \| volume = 24 \| issue = 8 \| pages = 1047-57 \| month = Aug \| year = 2000 \| doi = \| PMID = 10935645 }}</ref>		*Benign lymphangioendothelioma.<ref>{{Cite journal \| last1 = Guillou \| first1 = L. \| last2 = Fletcher \| first2 = CD. \| title = Benign lymphangioendothelioma (acquired progressive lymphangioma): a lesion not to be confused with well-differentiated angiosarcoma and patch stage Kaposi's sarcoma: clinicopathologic analysis of a series. \| journal = Am J Surg Pathol \| volume = 24 \| issue = 8 \| pages = 1047-57 \| month = Aug \| year = 2000 \| doi = \| PMID = 10935645 }}</ref>
	**Histologically very similar.<ref>URL: [http://path.upmc.edu/cases/case134/dx.html http://path.upmc.edu/cases/case134/dx.html]. Accessed on: 5 January 2012.</ref>		**Histologically very similar.<ref>URL: [http://path.upmc.edu/cases/case134/dx.html http://path.upmc.edu/cases/case134/dx.html]. Accessed on: 5 January 2012.</ref>
			*[[Caverous hemangioma]].<ref name=pmid24187557>PMID 24187557</ref>

	===Images===		===Images===

Michael: tweak

2013-10-15T01:21:13Z

tweak

← Older revision		Revision as of 01:21, 15 October 2013
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	\| Molecular =		\| Molecular =
	\| IF =		\| IF =
	\| Gross =		\| Gross = red or brown patches, plaques or nodules
	\| Grossing =		\| Grossing =
	\| Site = [[skin]], others		\| Site = [[skin]], others
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	*AIDS-associated.		*AIDS-associated.

			==Gross==
			*Skin: red or brown patches, plaques or nodules.

			<gallery>
			Image:Kaposis_sarcoma_01.jpg \| KS. (WC)
			</gallery>
	==Microscopic==		==Microscopic==
	Features:<ref name=Ref_Klatt23>{{Ref Klatt\|23}}</ref>		Features:<ref name=Ref_Klatt23>{{Ref Klatt\|23}}</ref>

Michael: +infobox

2013-10-15T01:17:15Z

+infobox

← Older revision		Revision as of 01:17, 15 October 2013
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			{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image = Kaposi_sarcoma_high_mag.jpg
			\| Width =
			\| Caption = Kaposi sarcoma. [[H&E stain]].
			\| Micro = vascular lesion (abundant [[RBC]]s), +/-"promontory sign", +/-spindle cells with minimal nuclear atypia, [[RBC extravasation]], +/-intracytoplasmic [[hyaline globules]], +/-hemosiderin deposits, +/-plasma cells
			\| Subtypes = classic, endemic, immunosuppression-associated ''or'' transplant-associated, AIDS-associated
			\| LMDDx = [[angiosarcoma]], [[Masson's hemangioma]] (''intravascular papillary endothelial hyperplasia''), benign lymphangioendothelioma
			\| Stains =
			\| IHC = HHV-8 +ve, CD31 +ve ,CD34 +ve
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross =
			\| Grossing =
			\| Site = [[skin]], others
			\| Assdx = +/-[[HIV]] infection ''or'' immunoincompentence
			\| Syndromes =
			\| Clinicalhx =
			\| Signs =
			\| Symptoms =
			\| Prevalence = uncommon
			\| Bloodwork =
			\| Rads =
			\| Endoscopy =
			\| Prognosis = dependent on subtype
			\| Other =
			\| ClinDDx =
			}}
	'''Kaposi sarcoma''', abbreviated '''KS''', is an uncommon [[vascular tumour]] that is often associated with [[HIV]]/AIDS.		'''Kaposi sarcoma''', abbreviated '''KS''', is an uncommon [[vascular tumour]] that is often associated with [[HIV]]/AIDS.