Low-grade fibromyxoid sarcoma - Revision history

Michael: touch

2014-11-16T22:40:21Z

touch

← Older revision		Revision as of 22:40, 16 November 2014
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	'''Low-grade fibromyxoid sarcoma''', abbreviated '''LGFMS''', is an uncommon [[malignant]] [[Fibroblastic/myofibroblastic tumours\|fibroblastic/myofibroblastic tumour]].		'''Low-grade fibromyxoid sarcoma''', abbreviated '''LGFMS''', is an uncommon [[malignant]] [[Fibroblastic/myofibroblastic tumours\|fibroblastic/myofibroblastic tumour]].

	It is also known as '''hyalinizing spindle cell tumour'''. It should '''not''' be confused with ''[[myxofibrosarcoma]]''.		It is also known as '''hyalinizing spindle cell tumour'''. It should '''not''' be confused with ''[[myxofibrosarcoma]]''.

	==General==		==General==

Michael: tweak

2014-11-16T00:15:22Z

tweak

← Older revision		Revision as of 00:15, 16 November 2014
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	'''Low-~~grade_fibromyxoid_sarcoma~~''', abbreviated '''LGFMS''', is an uncommon [[malignant]] [[Fibroblastic/myofibroblastic tumours\|fibroblastic/myofibroblastic tumour]].		'''Low-grade fibromyxoid sarcoma''', abbreviated '''LGFMS''', is an uncommon [[malignant]] [[Fibroblastic/myofibroblastic tumours\|fibroblastic/myofibroblastic tumour]].

	It is also known as '''hyalinizing spindle cell tumour'''. It should '''not''' be confused with ''[[myxofibrosarcoma]]''.		It is also known as '''hyalinizing spindle cell tumour'''. It should '''not''' be confused with ''[[myxofibrosarcoma]]''.

Michael: +images

2014-11-16T00:14:48Z

+images

← Older revision		Revision as of 00:14, 16 November 2014
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	~~#redirect~~ [[Fibroblastic/myofibroblastic tumours#Low-~~grade_fibromyxoid_sarcoma~~]]		'''Low-grade_fibromyxoid_sarcoma''', abbreviated '''LGFMS''', is an uncommon [[malignant]] [[Fibroblastic/myofibroblastic tumours\|fibroblastic/myofibroblastic tumour]].

			It is also known as '''hyalinizing spindle cell tumour'''. It should '''not''' be confused with ''[[myxofibrosarcoma]]''.

			==General==
			*Deep soft tissue.
			*Related to ''hyalinizing spindle cell tumour with giant collagen rosettes''.<ref name=pmid20864787>{{Cite journal \| last1 = Ramaswamy \| first1 = AS. \| last2 = Chatura \| first2 = KR. \| title = Hyalinizing spindle cell tumor with giant rosettes. \| journal = Ann Saudi Med \| volume = 31 \| issue = 1 \| pages = 83-6 \| month = \| year = \| doi = \| PMID = 20864787 \| PMC = 3101732 }}</ref>

			==Microscopic==
			Features:<ref>{{cite journal \|author=Vernon SE, Bejarano PA \|title=Low-grade fibromyxoid sarcoma: a brief review \|journal=Arch. Pathol. Lab. Med. \|volume=130 \|issue=9 \|pages=1358–60 \|year=2006 \|month=September \|pmid=16948525 \|doi= \|url=}}</ref>
			*[[Myxoid stroma]] alternating with fibrogenic areas - '''key feature'''.
			*Low cellularity.
			*Spindle cells.
			*+/-Rosette of collagen with central hyaline core.<ref name=Ref_WMSP611>{{Ref WMSP\|611}}</ref>

			Notes:
			*Few/absent mitoses.

			DDx:
			*[[Leiomyoma]].
			*[[Myxoid liposarcoma]].
			*[[Desmoplastic fibroblastoma]].
			*[[Intramuscular myxoma]].

			===Images===
			<gallery>
			Image:Low-grade_fibromyxoid_sarcoma_-_low_mag.jpg \| LGFMS - low mag. (WC)
			Image:Low-grade_fibromyxoid_sarcoma_-_intermed_mag.jpg \| LGFMS - intermed. mag. (WC)
			Image:Low-grade_fibromyxoid_sarcoma_-2-_high_mag.jpg \| LGFMS - high mag. (WC)
			</gallery>
			www:
			*[http://www.springerimages.com/Images/MedicineAndPublicHealth/1-10.1007_s00428-009-0776-0-7 LGFMS (springerimages.com)].
			*[http://www.uscap.org/site~/iap2006/slides18-2v.htm LGFMS (uscap.org)].

			==IHC==
			Features:<ref name=Ref_WMSP611>{{Ref WMSP\|611}}</ref>
			*EMA +ve.
			*CD99 +ve.
			*BCL2 +ve.

			Others:<ref name=Ref_WMSP611>{{Ref WMSP\|611}}</ref>
			*SMA -ve.
			*S100 -ve.
			*Desmin -ve.

			==Molecular pathology==
			*t(7;16)(q33;p11).<ref>{{cite journal \|author=Panagopoulos I, Storlazzi CT, Fletcher CD, ''et al.'' \|title=The chimeric FUS/CREB3l2 gene is specific for low-grade fibromyxoid sarcoma \|journal=Genes Chromosomes Cancer \|volume=40 \|issue=3 \|pages=218–28 \|year=2004 \|month=July \|pmid=15139001 \|doi=10.1002/gcc.20037 \|url=}}</ref>
			*t(11;16).<ref name=Ref_WMSP611>{{Ref WMSP\|611}}</ref>

			==See also==
			*[[Fibroblastic/myofibroblastic tumours]].

			==References==
			{{Reflist\|2}}

	[[Category:Diagnosis]]		[[Category:Diagnosis]]
			[[Category:Fibroblastic/myofibroblastic tumours]]

Michael: +cat.

2011-10-20T04:58:51Z

+cat.

← Older revision		Revision as of 04:58, 20 October 2011
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	#redirect [[Fibroblastic/myofibroblastic tumours#Low-grade_fibromyxoid_sarcoma]]		#redirect [[Fibroblastic/myofibroblastic tumours#Low-grade_fibromyxoid_sarcoma]]

			[[Category:Diagnosis]]

Michael: fix redirect

2011-05-18T18:13:50Z

fix redirect

← Older revision		Revision as of 18:13, 18 May 2011
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	#redirect [[~~Soft_tissue_lesions~~#Low-grade_fibromyxoid_sarcoma]]		#redirect [[Fibroblastic/myofibroblastic tumours#Low-grade_fibromyxoid_sarcoma]]

Michael: redirect

2011-04-06T15:03:43Z

redirect

New page

#redirect [[Soft_tissue_lesions#Low-grade_fibromyxoid_sarcoma]]