Micropapillary urothelial carcinoma - Revision history

Michael at 15:04, 21 March 2025

2025-03-21T15:04:31Z

← Older revision		Revision as of 15:04, 21 March 2025
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	*Report percentage of micropapillary pattern - suggested.{{fact}}		*Report percentage of micropapillary pattern - suggested.{{fact}}
	*In 2012, Amin and Epstein suggested that one distinguish between the invasive and non-invasive micropapillary pattern.<ref name=pmid22939957>{{Cite journal \| last1 = Amin \| first1 = A. \| last2 = Epstein \| first2 = JI. \| title = Noninvasive micropapillary urothelial carcinoma: a clinicopathologic study of 18 cases. \| journal = Hum Pathol \| volume = 43 \| issue = 12 \| pages = 2124-8 \| month = Dec \| year = 2012 \| doi = 10.1016/j.humpath.2012.04.013 \| PMID = 22939957 }}</ref> The WHO GU Book of 2016 suggests ''not'' using the term ''micropapillary carcinoma'' if only the non-invasive pattern is present (micropapillae ''without'' (invasive) nests of tumour with clefting to the surrounding stroma).<ref name=whogu2016_90>{{Ref WHOGU2016\|90}}</ref>		*In 2012, Amin and Epstein suggested that one distinguish between the invasive and non-invasive micropapillary pattern.<ref name=pmid22939957>{{Cite journal \| last1 = Amin \| first1 = A. \| last2 = Epstein \| first2 = JI. \| title = Noninvasive micropapillary urothelial carcinoma: a clinicopathologic study of 18 cases. \| journal = Hum Pathol \| volume = 43 \| issue = 12 \| pages = 2124-8 \| month = Dec \| year = 2012 \| doi = 10.1016/j.humpath.2012.04.013 \| PMID = 22939957 }}</ref> The WHO GU Book of 2016 suggests ''not'' using the term ''micropapillary carcinoma'' if only the non-invasive pattern is present (micropapillae ''without'' (invasive) nests of tumour with clefting to the surrounding stroma).<ref name=whogu2016_90>{{Ref WHOGU2016\|90}}</ref>

			===Microscopic in surface micropapillary change only===
			<pre>
			The surface of the tumour shows papillae without fibrovascular cores.
			</pre>

	==See also==		==See also==

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2018-09-06T13:45:48Z

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← Older revision		Revision as of 13:45, 6 September 2018
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	*Report percentage of micropapillary pattern - suggested.{{fact}}		*Report percentage of micropapillary pattern - suggested.{{fact}}
	*In 2012, Amin and Epstein suggested that one distinguish between the invasive and non-invasive micropapillary pattern.<ref name=pmid22939957>{{Cite journal \| last1 = Amin \| first1 = A. \| last2 = Epstein \| first2 = JI. \| title = Noninvasive micropapillary urothelial carcinoma: a clinicopathologic study of 18 cases. \| journal = Hum Pathol \| volume = 43 \| issue = 12 \| pages = 2124-8 \| month = Dec \| year = 2012 \| doi = 10.1016/j.humpath.2012.04.013 \| PMID = 22939957 }}</ref> The WHO GU Book of 2016 suggests ''not'' using the term ''micropapillary carcinoma'' if only the non-invasive pattern is present (micropapillae ''without'' nests of tumour with clefting to the surrounding stroma).<ref name=whogu2016_90>{{Ref WHOGU2016\|90}}</ref>		*In 2012, Amin and Epstein suggested that one distinguish between the invasive and non-invasive micropapillary pattern.<ref name=pmid22939957>{{Cite journal \| last1 = Amin \| first1 = A. \| last2 = Epstein \| first2 = JI. \| title = Noninvasive micropapillary urothelial carcinoma: a clinicopathologic study of 18 cases. \| journal = Hum Pathol \| volume = 43 \| issue = 12 \| pages = 2124-8 \| month = Dec \| year = 2012 \| doi = 10.1016/j.humpath.2012.04.013 \| PMID = 22939957 }}</ref> The WHO GU Book of 2016 suggests ''not'' using the term ''micropapillary carcinoma'' if only the non-invasive pattern is present (micropapillae ''without'' (invasive) nests of tumour with clefting to the surrounding stroma).<ref name=whogu2016_90>{{Ref WHOGU2016\|90}}</ref>

	==See also==		==See also==

Michael: /* Sign out */

2018-09-06T13:45:24Z

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← Older revision		Revision as of 13:45, 6 September 2018
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	*Report percentage of micropapillary pattern - suggested.{{fact}}		*Report percentage of micropapillary pattern - suggested.{{fact}}
	*In 2012, Amin and Epstein suggested that one distinguish between the invasive and non-invasive micropapillary pattern.<ref name=pmid22939957>{{Cite journal \| last1 = Amin \| first1 = A. \| last2 = Epstein \| first2 = JI. \| title = Noninvasive micropapillary urothelial carcinoma: a clinicopathologic study of 18 cases. \| journal = Hum Pathol \| volume = 43 \| issue = 12 \| pages = 2124-8 \| month = Dec \| year = 2012 \| doi = 10.1016/j.humpath.2012.04.013 \| PMID = 22939957 }}</ref> The WHO GU Book of 2016 suggests ''not'' using the term ''micropapillary carcinoma'' if only the non-invasive pattern is present (micropapillae '''without''' nests of tumour with clefting to the surrounding stroma).<ref name=whogu2016_90>{{Ref WHOGU2016\|90}}</ref>		*In 2012, Amin and Epstein suggested that one distinguish between the invasive and non-invasive micropapillary pattern.<ref name=pmid22939957>{{Cite journal \| last1 = Amin \| first1 = A. \| last2 = Epstein \| first2 = JI. \| title = Noninvasive micropapillary urothelial carcinoma: a clinicopathologic study of 18 cases. \| journal = Hum Pathol \| volume = 43 \| issue = 12 \| pages = 2124-8 \| month = Dec \| year = 2012 \| doi = 10.1016/j.humpath.2012.04.013 \| PMID = 22939957 }}</ref> The WHO GU Book of 2016 suggests ''not'' using the term ''micropapillary carcinoma'' if only the non-invasive pattern is present (micropapillae ''without'' nests of tumour with clefting to the surrounding stroma).<ref name=whogu2016_90>{{Ref WHOGU2016\|90}}</ref>

	==See also==		==See also==

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2018-09-06T13:45:05Z

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	*Report percentage of micropapillary pattern - suggested.{{fact}}		*Report percentage of micropapillary pattern - suggested.{{fact}}
	*In 2012, Amin and Epstein suggested that one distinguish between the invasive and non-invasive micropapillary pattern.<ref name=pmid22939957>{{Cite journal \| last1 = Amin \| first1 = A. \| last2 = Epstein \| first2 = JI. \| title = Noninvasive micropapillary urothelial carcinoma: a clinicopathologic study of 18 cases. \| journal = Hum Pathol \| volume = 43 \| issue = 12 \| pages = 2124-8 \| month = Dec \| year = 2012 \| doi = 10.1016/j.humpath.2012.04.013 \| PMID = 22939957 }}</ref> The WHO GU Book of 2016 suggests not using the term ''micropapillary carcinoma'' if only the non-invasive pattern is present.<ref name=whogu2016_90>{{Ref WHOGU2016\|90}}</ref>		*In 2012, Amin and Epstein suggested that one distinguish between the invasive and non-invasive micropapillary pattern.<ref name=pmid22939957>{{Cite journal \| last1 = Amin \| first1 = A. \| last2 = Epstein \| first2 = JI. \| title = Noninvasive micropapillary urothelial carcinoma: a clinicopathologic study of 18 cases. \| journal = Hum Pathol \| volume = 43 \| issue = 12 \| pages = 2124-8 \| month = Dec \| year = 2012 \| doi = 10.1016/j.humpath.2012.04.013 \| PMID = 22939957 }}</ref> The WHO GU Book of 2016 suggests ''not'' using the term ''micropapillary carcinoma'' if only the non-invasive pattern is present (micropapillae '''without''' nests of tumour with clefting to the surrounding stroma).<ref name=whogu2016_90>{{Ref WHOGU2016\|90}}</ref>

	==See also==		==See also==

Michael at 13:43, 6 September 2018

2018-09-06T13:43:32Z

← Older revision		Revision as of 13:43, 6 September 2018
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	\| Caption = Urothelial carcinoma with invasive micropapillary features. [[H&E stain]].		\| Caption = Urothelial carcinoma with invasive micropapillary features. [[H&E stain]].
	\| Synonyms =		\| Synonyms =
	\| Micro = nests of tumour cells with clefting to the surrounding stroma (invasive pattern)		\| Micro = nests of tumour cells with clefting to the surrounding stroma (invasive pattern) ''or'' micropapillae (nipple-like structures without fibrovascular cores)
	\| Subtypes = (subtype of [[urothelial carcinoma]])		\| Subtypes = (subtype of [[urothelial carcinoma]])
	\| LMDDx = conventional [[urothelial carcinoma]], other micropapillary carcinomas ([[metastases]])		\| LMDDx = conventional [[urothelial carcinoma]], other micropapillary carcinomas ([[metastases]])

Michael: /* Microscopic */

2018-09-06T13:41:40Z

Microscopic

← Older revision		Revision as of 13:41, 6 September 2018
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	#Micropapillae:<ref name=pmid21080874/>		#Micropapillae:<ref name=pmid21080874/>
	#*Nipple-like structures without fibrovascular cores.		#*Nipple-like structures without fibrovascular cores.
	#~~The~~ invasive pattern of ''micropapillary urothelial carcinoma'' ~~is nests of tumour cells with clefting to the surrounding stroma~~.		#Nests of tumour cells with clefting to the surrounding stroma - this is the invasive pattern of ''micropapillary urothelial carcinoma''.
	*+/-Conventional [[urothelial carcinoma]] (common).		*+/-Conventional [[urothelial carcinoma]] (common).

Michael: /* Microscopic */

2018-09-06T13:40:36Z

Microscopic

← Older revision		Revision as of 13:40, 6 September 2018
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	==Microscopic==		==Microscopic==
	Features:<ref name=pmid21080874/>		Features - either:
	*Micropapillae - '''definitional'''.		#Micropapillae:<ref name=pmid21080874/>
	**Nipple-like structures without fibrovascular cores.		#*Nipple-like structures without fibrovascular cores.
	**Quantity of micropapillary ~~pattern (percentage)~~ is ~~variable~~.~~<ref name=pmid25673582/>~~		#The invasive pattern of ''micropapillary urothelial carcinoma'' is nests of tumour cells with clefting to the surrounding stroma.
	*+/-Conventional [[urothelial carcinoma]] (~~typical~~).		*+/-Conventional [[urothelial carcinoma]] (common).

	Notes:		Notes:
	*The invasive pattern of ''micropapillary urothelial carcinoma'' is nests of tumour cells with clefting to the surrounding stroma.		*In other organs, [[adenocarcinoma]] would be in the differential diagnosis. It should be noted that (primary) [[adenocarcinoma of the urinary bladder]] looks quite different than ''micropapillary urothelial carcinoma''.
	*In other organs, [[adenocarcinoma]] would be in the differential diagnosis. It should be noted that [[adenocarcinoma of the urinary bladder]] looks quite different than ''micropapillary urothelial carcinoma''.		*Quantity of micropapillary pattern (percentage) is variable.<ref name=pmid25673582/>

	DDx:		DDx:

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2018-09-05T18:51:16Z

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	*Report percentage of micropapillary pattern - suggested.{{fact}}		*Report percentage of micropapillary pattern - suggested.{{fact}}
	*~~It is~~ suggested that one ~~distinction~~ between invasive and non-invasive micropapillary pattern;<ref name=pmid22939957>{{Cite journal \| last1 = Amin \| first1 = A. \| last2 = Epstein \| first2 = JI. \| title = Noninvasive micropapillary urothelial carcinoma: a clinicopathologic study of 18 cases. \| journal = Hum Pathol \| volume = 43 \| issue = 12 \| pages = 2124-8 \| month = Dec \| year = 2012 \| doi = 10.1016/j.humpath.2012.04.013 \| PMID = 22939957 }}</ref> ~~the~~ WHO GU Book of 2016 suggests not using the term ''micropapillary carcinoma'' if only the non-invasive pattern is present.<ref name=whogu2016_90>{{Ref WHOGU2016\|90}}</ref>		*In 2012, Amin and Epstein suggested that one distinguish between the invasive and non-invasive micropapillary pattern.<ref name=pmid22939957>{{Cite journal \| last1 = Amin \| first1 = A. \| last2 = Epstein \| first2 = JI. \| title = Noninvasive micropapillary urothelial carcinoma: a clinicopathologic study of 18 cases. \| journal = Hum Pathol \| volume = 43 \| issue = 12 \| pages = 2124-8 \| month = Dec \| year = 2012 \| doi = 10.1016/j.humpath.2012.04.013 \| PMID = 22939957 }}</ref> The WHO GU Book of 2016 suggests not using the term ''micropapillary carcinoma'' if only the non-invasive pattern is present.<ref name=whogu2016_90>{{Ref WHOGU2016\|90}}</ref>

	==See also==		==See also==

Michael: /* Sign out */

2018-09-05T18:49:25Z

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	*Report percentage of micropapillary pattern - suggested.{{fact}}		*Report percentage of micropapillary pattern - suggested.{{fact}}
	*It is suggested that one distinction between invasive and non-invasive micropapillary pattern;<ref name=pmid22939957>{{Cite journal \| last1 = Amin \| first1 = A. \| last2 = Epstein \| first2 = JI. \| title = Noninvasive micropapillary urothelial carcinoma: a clinicopathologic study of 18 cases. \| journal = Hum Pathol \| volume = 43 \| issue = 12 \| pages = 2124-8 \| month = Dec \| year = 2012 \| doi = 10.1016/j.humpath.2012.04.013 \| PMID = 22939957 }}</ref> the WHO GU Book of 2016 suggests not using the term ''micropapillary carcinoma'' if only the non-invasive pattern is present.<ref name=whogu2016_90>{{WHOGU2016\|90}}</ref>		*It is suggested that one distinction between invasive and non-invasive micropapillary pattern;<ref name=pmid22939957>{{Cite journal \| last1 = Amin \| first1 = A. \| last2 = Epstein \| first2 = JI. \| title = Noninvasive micropapillary urothelial carcinoma: a clinicopathologic study of 18 cases. \| journal = Hum Pathol \| volume = 43 \| issue = 12 \| pages = 2124-8 \| month = Dec \| year = 2012 \| doi = 10.1016/j.humpath.2012.04.013 \| PMID = 22939957 }}</ref> the WHO GU Book of 2016 suggests not using the term ''micropapillary carcinoma'' if only the non-invasive pattern is present.<ref name=whogu2016_90>{{Ref WHOGU2016\|90}}</ref>

	==See also==		==See also==

Michael: /* Sign out */

2018-09-05T18:49:11Z

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← Older revision		Revision as of 18:49, 5 September 2018
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	*Report percentage of micropapillary pattern - suggested.{{fact}}		*Report percentage of micropapillary pattern - suggested.{{fact}}
	*It is suggested that one distinction between invasive and non-invasive micropapillary pattern.<ref name=pmid22939957>{{Cite journal \| last1 = Amin \| first1 = A. \| last2 = Epstein \| first2 = JI. \| title = Noninvasive micropapillary urothelial carcinoma: a clinicopathologic study of 18 cases. \| journal = Hum Pathol \| volume = 43 \| issue = 12 \| pages = 2124-8 \| month = Dec \| year = 2012 \| doi = 10.1016/j.humpath.2012.04.013 \| PMID = 22939957 }}</ref>		*It is suggested that one distinction between invasive and non-invasive micropapillary pattern;<ref name=pmid22939957>{{Cite journal \| last1 = Amin \| first1 = A. \| last2 = Epstein \| first2 = JI. \| title = Noninvasive micropapillary urothelial carcinoma: a clinicopathologic study of 18 cases. \| journal = Hum Pathol \| volume = 43 \| issue = 12 \| pages = 2124-8 \| month = Dec \| year = 2012 \| doi = 10.1016/j.humpath.2012.04.013 \| PMID = 22939957 }}</ref> the WHO GU Book of 2016 suggests not using the term ''micropapillary carcinoma'' if only the non-invasive pattern is present.<ref name=whogu2016_90>{{WHOGU2016\|90}}</ref>

	==See also==		==See also==