Mucinous adenocarcinoma of the prostate - Revision history

Michael at 03:18, 13 June 2016

2016-06-13T03:18:14Z

← Older revision		Revision as of 03:18, 13 June 2016
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	\| Image = Mucinous adenocarcinoma of prostate - 2b -- high mag.jpg		\| Image = Mucinous adenocarcinoma of prostate - 2b -- high mag.jpg
	\| Width =		\| Width =
	\| Caption = Mucinous adenocarcinoma of the prostate (left) with acinar adenocarcinoma of the prostate (right). [[H&E stain]]. (WC/Nephron)		\| Caption = Mucinous adenocarcinoma of the prostate (left of image) with acinar adenocarcinoma of the prostate (right of image). [[H&E stain]]. (WC/Nephron)
	\| Synonyms =		\| Synonyms =
	\| Micro = cytologically malignant (prostatic) cells floating in mucin; >25% of tumour mucinous		\| Micro = cytologically malignant (prostatic) cells floating in mucin; >25% of tumour mucinous

Michael at 03:17, 13 June 2016

2016-06-13T03:17:54Z

← Older revision		Revision as of 03:17, 13 June 2016
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	\| Image = Mucinous adenocarcinoma of prostate - 2b -- high mag.jpg		\| Image = Mucinous adenocarcinoma of prostate - 2b -- high mag.jpg
	\| Width =		\| Width =
	\| Caption = Mucinous adenocarcinoma of the prostate. [[H&E stain]]. (WC/Nephron)		\| Caption = Mucinous adenocarcinoma of the prostate (left) with acinar adenocarcinoma of the prostate (right). [[H&E stain]]. (WC/Nephron)
	\| Synonyms =		\| Synonyms =
	\| Micro = cytologically malignant (prostatic) cells floating in mucin; >25% of tumour mucinous		\| Micro = cytologically malignant (prostatic) cells floating in mucin; >25% of tumour mucinous

Michael at 03:17, 13 June 2016

2016-06-13T03:17:09Z

← Older revision		Revision as of 03:17, 13 June 2016
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	{{ Infobox diagnosis		{{ Infobox diagnosis
	\| Name = {{PAGENAME}}		\| Name = {{PAGENAME}}
	\| Image = Mucinous adenocarcinoma of prostate -- high mag.jpg		\| Image = Mucinous adenocarcinoma of prostate - 2b -- high mag.jpg
	\| Width =		\| Width =
	\| Caption = Mucinous adenocarcinoma of the prostate. [[H&E stain]]. (WC/Nephron)		\| Caption = Mucinous adenocarcinoma of the prostate. [[H&E stain]]. (WC/Nephron)

Michael: /* Microscopic */

2016-06-11T12:19:05Z

Microscopic

← Older revision		Revision as of 12:19, 11 June 2016
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	*Metastatic [[mucinous carcinoma]].		*Metastatic [[mucinous carcinoma]].
	*Mucinous adenocarcinoma of the prostatic urethra - analogous to the mucinous adenocarcinoma of the [[urinary bladder]].<ref name=pmid23060063/>		*Mucinous adenocarcinoma of the prostatic urethra - analogous to the mucinous adenocarcinoma of the [[urinary bladder]].<ref name=pmid23060063/>

			===Images===
			<gallery>
			Image: Mucinous adenocarcinoma of prostate -- low mag.jpg \| MAP - low mag. (WC/Nephron)
			Image: Mucinous adenocarcinoma of prostate -- intermed mag.jpg \| MAP - intermed. mag. (WC/Nephron)
			Image: Mucinous adenocarcinoma of prostate -- high mag.jpg \| MAP - high mag. (WC/Nephron)
			Image: Mucinous adenocarcinoma of prostate -- very high mag.jpg \| MAP - very high mag. (WC/Nephron)

			Image: Mucinous adenocarcinoma of prostate - alt -- low mag.jpg \| MAP - low mag. (WC/Nephron)

			Image: Mucinous adenocarcinoma of prostate - 2 -- intermed mag.jpg \| MAP - intermed. mag. (WC/Nephron)
			Image: Mucinous adenocarcinoma of prostate - 2a -- high mag.jpg \| MAP - high mag. (WC/Nephron)
			Image: Mucinous adenocarcinoma of prostate - 2b -- high mag.jpg \| MAP - high mag. (WC/Nephron)
			</gallery>

	==See also==		==See also==

Michael: +image

2016-06-11T12:14:23Z

+image

← Older revision		Revision as of 12:14, 11 June 2016
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	{{ Infobox diagnosis		{{ Infobox diagnosis
	\| Name = {{PAGENAME}}		\| Name = {{PAGENAME}}
	\| Image =		\| Image = Mucinous adenocarcinoma of prostate -- high mag.jpg
	\| Width =		\| Width =
	\| Caption =		\| Caption = Mucinous adenocarcinoma of the prostate. [[H&E stain]]. (WC/Nephron)
	\| Synonyms =		\| Synonyms =
	\| Micro = cytologically malignant (prostatic) cells floating in mucin; >25% of tumour mucinous		\| Micro = cytologically malignant (prostatic) cells floating in mucin; >25% of tumour mucinous
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	\| IF =		\| IF =
	\| Gross =		\| Gross =
	\| Grossing =		\| Grossing = [[prostatectomy grossing]], [[TURP specimens]]
	\| Staging =		\| Staging =
	\| Site = [[prostate gland]] - see ''[[prostate cancer]]''		\| Site = [[prostate gland]] - see ''[[prostate cancer]]''

Michael at 05:37, 11 June 2016

2016-06-11T05:37:44Z

← Older revision		Revision as of 05:37, 11 June 2016
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			{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image =
			\| Width =
			\| Caption =
			\| Synonyms =
			\| Micro = cytologically malignant (prostatic) cells floating in mucin; >25% of tumour mucinous
			\| Subtypes =
			\| LMDDx = acinar adenocarcinoma of the prostate with a minor mucinous component (<25%), metastatic [[mucinous carcinoma]], mucinous adenocarcinoma of the prostatic urethra
			\| Stains =
			\| IHC =
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross =
			\| Grossing =
			\| Staging =
			\| Site = [[prostate gland]] - see ''[[prostate cancer]]''
			\| Assdx =
			\| Syndromes =
			\| Clinicalhx =
			\| Signs =
			\| Symptoms =
			\| Prevalence = rare
			\| Bloodwork = PSA elevated
			\| Rads =
			\| Endoscopy =
			\| Prognosis = dependent on grade
			\| Other =
			\| ClinDDx =
			\| Tx = prostatectomy, radiation or observation
			}}
	'''Mucinous adenocarcinoma of the prostate''' is an uncommon type of [[prostate cancer]].		'''Mucinous adenocarcinoma of the prostate''' is an uncommon type of [[prostate cancer]].

Michael: /* General */

2016-06-11T05:33:12Z

General

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	==General==		==General==
	*Rare.		*Rare.<ref name=pmid18300802/>
	*Most often Gleason 3+4 ~ 80% in one series of 47 cases.<ref name=pmid18300802>{{Cite journal \| last1 = Osunkoya \| first1 = AO. \| last2 = Nielsen \| first2 = ME. \| last3 = Epstein \| first3 = JI. \| title = Prognosis of mucinous adenocarcinoma of the prostate treated by radical prostatectomy: a study of 47 cases. \| journal = Am J Surg Pathol \| volume = 32 \| issue = 3 \| pages = 468-72 \| month = Mar \| year = 2008 \| doi = 10.1097/PAS.0b013e3181589f72 \| PMID = 18300802 }}</ref>		*Most often Gleason 3+4 ~ 80% in one series of 47 cases.<ref name=pmid18300802>{{Cite journal \| last1 = Osunkoya \| first1 = AO. \| last2 = Nielsen \| first2 = ME. \| last3 = Epstein \| first3 = JI. \| title = Prognosis of mucinous adenocarcinoma of the prostate treated by radical prostatectomy: a study of 47 cases. \| journal = Am J Surg Pathol \| volume = 32 \| issue = 3 \| pages = 468-72 \| month = Mar \| year = 2008 \| doi = 10.1097/PAS.0b013e3181589f72 \| PMID = 18300802 }}</ref>

Michael: split out

2016-06-11T05:31:28Z

split out

New page

'''Mucinous adenocarcinoma of the prostate''' is an uncommon type of [[prostate cancer]].

==General==
*Rare.
*Most often Gleason 3+4 ~ 80% in one series of 47 cases.<ref name=pmid18300802>{{Cite journal | last1 = Osunkoya | first1 = AO. | last2 = Nielsen | first2 = ME. | last3 = Epstein | first3 = JI. | title = Prognosis of mucinous adenocarcinoma of the prostate treated by radical prostatectomy: a study of 47 cases. | journal = Am J Surg Pathol | volume = 32 | issue = 3 | pages = 468-72 | month = Mar | year = 2008 | doi = 10.1097/PAS.0b013e3181589f72 | PMID = 18300802 }}</ref>

Gleason pattern:
*In the past, it has been suggested that the mucinous component be assigned ''Gleason pattern 4''.<ref name=pmid14976541>{{cite journal |author=Grignon DJ |title=Unusual subtypes of prostate cancer |journal=Mod. Pathol. |volume=17 |issue=3 |pages=316–27 |year=2004 |month=March |pmid=14976541 |doi=10.1038/modpathol.3800052 |url=}}</ref>
*The prognosis is similar or may be better than the conventional type of prostate cancer in a large series;<ref name=pmid18300802/> thus, it seems reasonable to grade based on the pattern (as advocated by some experts<ref name=pmid18487999>{{Cite journal | last1 = Osunkoya | first1 = AO. | last2 = Adsay | first2 = NV. | last3 = Cohen | first3 = C. | last4 = Epstein | first4 = JI. | last5 = Smith | first5 = SL. | title = MUC2 expression in primary mucinous and nonmucinous adenocarcinoma of the prostate: an analysis of 50 cases on radical prostatectomy. | journal = Mod Pathol | volume = 21 | issue = 7 | pages = 789-94 | month = Jul | year = 2008 | doi = 10.1038/modpathol.2008.47 | PMID = 18487999 }}</ref>).

==Microscopic==
Features:
*Cytologically malignant cells floating in mucin.
*> 25% of tumour mucinous.<ref name=pmid14976541>{{cite journal |author=Grignon DJ |title=Unusual subtypes of prostate cancer |journal=Mod. Pathol. |volume=17 |issue=3 |pages=316–27 |year=2004 |month=March |pmid=14976541 |doi=10.1038/modpathol.3800052 |url=}}</ref>
**Two studies suggests '''>=''' 25%.<ref>{{cite journal |author=Osunkoya AO, Nielsen ME, Epstein JI |title=Prognosis of mucinous adenocarcinoma of the prostate treated by radical prostatectomy: a study of 47 cases |journal=Am. J. Surg. Pathol. |volume=32 |issue=3 |pages=468–72 |year=2008 |month=March |pmid=18300802 |doi=10.1097/PAS.0b013e3181589f72 |url=}}</ref><ref name=pmid23060063>{{Cite journal | last1 = Bohman | first1 = KD. | last2 = Osunkoya | first2 = AO. | title = Mucin-producing tumors and tumor-like lesions involving the prostate: a comprehensive review. | journal = Adv Anat Pathol | volume = 19 | issue = 6 | pages = 374-87 | month = Nov | year = 2012 | doi = 10.1097/PAP.0b013e318271a361 | PMID = 23060063 }}</ref>

Notes:
*[[Mucinous carcinoma]] - percentage required to call varies by site.

DDx:
*Metastatic [[mucinous carcinoma]].
*Mucinous adenocarcinoma of the prostatic urethra - analogous to the mucinous adenocarcinoma of the [[urinary bladder]].<ref name=pmid23060063/>

==See also==
*[[Prostate cancer]].
*[[Mucinous adenocarcinoma]].

==References==
{{Reflist|1}}

[[Category:Diagnosis]]
[[Category:Prostate carcinoma]]