Mucoepidermoid carcinoma - Revision history

Michael: vauthors

2021-03-25T17:15:38Z

vauthors

← Older revision		Revision as of 17:15, 25 March 2021
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	Note:		Note:
	*May mimic a benign cystic lesion grossly.		*May mimic a benign cystic lesion grossly.
	*Unicystic mucoepidermoid carcinoma is rare.<ref name=pmid22843640>{{cite journal \|~~vauthors~~=Qannam A, Bello IO, Al-Kindi M, Al-Hindi M \|title=Unicystic mucoepidermoid carcinoma presenting as a salivary duct cyst \|journal=Int J Surg Pathol \|volume=21 \|issue=2 \|pages=181–5 \|date=April 2013 \|pmid=22843640 \|doi=10.1177/1066896912454918 \|url=}}</ref>		*Unicystic mucoepidermoid carcinoma is rare.<ref name=pmid22843640>{{cite journal \|authors=Qannam A, Bello IO, Al-Kindi M, Al-Hindi M \|title=Unicystic mucoepidermoid carcinoma presenting as a salivary duct cyst \|journal=Int J Surg Pathol \|volume=21 \|issue=2 \|pages=181–5 \|date=April 2013 \|pmid=22843640 \|doi=10.1177/1066896912454918 \|url=}}</ref>

	==Microscopic==		==Microscopic==

Michael: /* IHC */

2020-10-28T16:50:18Z

IHC

← Older revision		Revision as of 16:50, 28 October 2020
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	*CK20 -ve.		*CK20 -ve.
	*CEA +ve.<ref>{{Cite journal \| last1 = Hassanin \| first1 = MB. \| last2 = Ghosh \| first2 = L. \| last3 = Das \| first3 = AK. \| last4 = Waterhouse \| first4 = JP. \| title = Immunohistochemical and fluorescent microscopic study of histogenesis of salivary mucoepidermoid carcinoma. \| journal = J Oral Pathol Med \| volume = 18 \| issue = 5 \| pages = 291-8 \| month = May \| year = 1989 \| doi = \| PMID = 2475619 }}</ref>		*CEA +ve.<ref>{{Cite journal \| last1 = Hassanin \| first1 = MB. \| last2 = Ghosh \| first2 = L. \| last3 = Das \| first3 = AK. \| last4 = Waterhouse \| first4 = JP. \| title = Immunohistochemical and fluorescent microscopic study of histogenesis of salivary mucoepidermoid carcinoma. \| journal = J Oral Pathol Med \| volume = 18 \| issue = 5 \| pages = 291-8 \| month = May \| year = 1989 \| doi = \| PMID = 2475619 }}</ref>

			==Sign out==
			<pre>
			A. Lymph Node, Deep Lobe of Left Parotid Gland, Excision:
			- One lymph node NEGATIVE for malignancy (0/1).

			B. Parotid Gland - Left Deep Lobe, Excision:
			- MUCOEPIDERMOID CARCINOMA, low (AFIP) grade.
			-- Margins clear.
			-- Please see synoptic report.
			</pre>

	==Molecular==		==Molecular==

Michael: /* Gross */

2020-10-28T16:47:35Z

Gross

← Older revision		Revision as of 16:47, 28 October 2020
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	Note:		Note:
			*May mimic a benign cystic lesion grossly.
	*Unicystic mucoepidermoid carcinoma is rare.<ref name=pmid22843640>{{cite journal \|vauthors=Qannam A, Bello IO, Al-Kindi M, Al-Hindi M \|title=Unicystic mucoepidermoid carcinoma presenting as a salivary duct cyst \|journal=Int J Surg Pathol \|volume=21 \|issue=2 \|pages=181–5 \|date=April 2013 \|pmid=22843640 \|doi=10.1177/1066896912454918 \|url=}}</ref>		*Unicystic mucoepidermoid carcinoma is rare.<ref name=pmid22843640>{{cite journal \|vauthors=Qannam A, Bello IO, Al-Kindi M, Al-Hindi M \|title=Unicystic mucoepidermoid carcinoma presenting as a salivary duct cyst \|journal=Int J Surg Pathol \|volume=21 \|issue=2 \|pages=181–5 \|date=April 2013 \|pmid=22843640 \|doi=10.1177/1066896912454918 \|url=}}</ref>

Michael: /* Gross */

2020-10-28T16:45:44Z

Gross

← Older revision		Revision as of 16:45, 28 October 2020
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	==Gross==		==Gross==
	*Cystic or solid, ~~usu.~~ a mix of both.		*Cystic or solid, usually a mix of both.

			Note:
			*Unicystic mucoepidermoid carcinoma is rare.<ref name=pmid22843640>{{cite journal \|vauthors=Qannam A, Bello IO, Al-Kindi M, Al-Hindi M \|title=Unicystic mucoepidermoid carcinoma presenting as a salivary duct cyst \|journal=Int J Surg Pathol \|volume=21 \|issue=2 \|pages=181–5 \|date=April 2013 \|pmid=22843640 \|doi=10.1177/1066896912454918 \|url=}}</ref>

	==Microscopic==		==Microscopic==

Brigitte: /* Images */

2018-04-26T02:25:59Z

Images

← Older revision		Revision as of 02:25, 26 April 2018
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	</gallery>		</gallery>
	www:		www:
	*[http://moon.ouhsc.edu/kfung/jty1/opaq/PathQuiz/D2A001-PQ01-M.htm Mucoepidermoid carcinoma (ouhsc.edu)].
	*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256999/figure/f2-cpath-5-2012-001/ Low-grade MEC (nih.gov)].<ref name=pmid22262946>{{Cite journal \| last1 = Mokhtari \| first1 = S. \| last2 = Mokhtari \| first2 = S. \| title = Clinical features and differential diagnoses in laryngeal mucoepidermoid carcinoma. \| journal = Clin Med Insights Pathol \| volume = 5 \| issue = \| pages = 1-6 \| month = \| year = 2012 \| doi = 10.4137/CPath.S8435 \| PMID = 22262946 }}</ref>		*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256999/figure/f2-cpath-5-2012-001/ Low-grade MEC (nih.gov)].<ref name=pmid22262946>{{Cite journal \| last1 = Mokhtari \| first1 = S. \| last2 = Mokhtari \| first2 = S. \| title = Clinical features and differential diagnoses in laryngeal mucoepidermoid carcinoma. \| journal = Clin Med Insights Pathol \| volume = 5 \| issue = \| pages = 1-6 \| month = \| year = 2012 \| doi = 10.4137/CPath.S8435 \| PMID = 22262946 }}</ref>
	*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256999/figure/f3-cpath-5-2012-001/ Intermed. grade MEC (nih.gov)].		*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256999/figure/f3-cpath-5-2012-001/ Intermed. grade MEC (nih.gov)].

Michael: /* See also */

2018-03-20T03:37:53Z

Michael: /* Microscopic */

2017-01-06T19:09:57Z

Microscopic

← Older revision		Revision as of 19:09, 6 January 2017
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	DDx:<ref name=pmid22262946>{{Cite journal \| last1 = Mokhtari \| first1 = S. \| last2 = Mokhtari \| first2 = S. \| title = Clinical features and differential diagnoses in laryngeal mucoepidermoid carcinoma. \| journal = Clin Med Insights Pathol \| volume = 5 \| issue = \| pages = 1-6 \| month = \| year = 2012 \| doi = 10.4137/CPath.S8435 \| PMID = 22262946 }}</ref>		DDx:<ref name=pmid22262946>{{Cite journal \| last1 = Mokhtari \| first1 = S. \| last2 = Mokhtari \| first2 = S. \| title = Clinical features and differential diagnoses in laryngeal mucoepidermoid carcinoma. \| journal = Clin Med Insights Pathol \| volume = 5 \| issue = \| pages = 1-6 \| month = \| year = 2012 \| doi = 10.4137/CPath.S8435 \| PMID = 22262946 }}</ref>
	*[[Squamous cell carcinoma of the skin]] ~75% of metastases to the parotid region.<ref name=pmid2694753>{{Cite journal \| last1 = Zanetti \| first1 = D. \| last2 = Renaldini \| first2 = G. \| last3 = Peretti \| first3 = G. \| last4 = Antonelli \| first4 = AR. \| title = [Intra-parotid lymph node metastasis of malignant skin neoplasms of the head]. \| journal = Acta Otorhinolaryngol Ital \| volume = 9 \| issue = 4 \| pages = 381-90 \| month = \| year = \| doi = \| PMID = 2694753 }}</ref>		*[[Squamous cell carcinoma of the skin]] - 75% of metastases to the parotid region are from the skin.<ref name=pmid2694753>{{Cite journal \| last1 = Zanetti \| first1 = D. \| last2 = Renaldini \| first2 = G. \| last3 = Peretti \| first3 = G. \| last4 = Antonelli \| first4 = AR. \| title = [Intra-parotid lymph node metastasis of malignant skin neoplasms of the head]. \| journal = Acta Otorhinolaryngol Ital \| volume = 9 \| issue = 4 \| pages = 381-90 \| month = \| year = \| doi = \| PMID = 2694753 }}</ref>
	*[[Squamous cell carcinoma of the head and neck]].		*[[Squamous cell carcinoma of the head and neck]].
	*[[Adenosquamous carcinoma]].		*[[Adenosquamous carcinoma]].

Michael: /* Microscopic */

2017-01-06T19:09:07Z

Microscopic

← Older revision		Revision as of 19:09, 6 January 2017
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	DDx:<ref name=pmid22262946>{{Cite journal \| last1 = Mokhtari \| first1 = S. \| last2 = Mokhtari \| first2 = S. \| title = Clinical features and differential diagnoses in laryngeal mucoepidermoid carcinoma. \| journal = Clin Med Insights Pathol \| volume = 5 \| issue = \| pages = 1-6 \| month = \| year = 2012 \| doi = 10.4137/CPath.S8435 \| PMID = 22262946 }}</ref>		DDx:<ref name=pmid22262946>{{Cite journal \| last1 = Mokhtari \| first1 = S. \| last2 = Mokhtari \| first2 = S. \| title = Clinical features and differential diagnoses in laryngeal mucoepidermoid carcinoma. \| journal = Clin Med Insights Pathol \| volume = 5 \| issue = \| pages = 1-6 \| month = \| year = 2012 \| doi = 10.4137/CPath.S8435 \| PMID = 22262946 }}</ref>
			*[[Squamous cell carcinoma of the skin]] ~75% of metastases to the parotid region.<ref name=pmid2694753>{{Cite journal \| last1 = Zanetti \| first1 = D. \| last2 = Renaldini \| first2 = G. \| last3 = Peretti \| first3 = G. \| last4 = Antonelli \| first4 = AR. \| title = [Intra-parotid lymph node metastasis of malignant skin neoplasms of the head]. \| journal = Acta Otorhinolaryngol Ital \| volume = 9 \| issue = 4 \| pages = 381-90 \| month = \| year = \| doi = \| PMID = 2694753 }}</ref>
	*[[Squamous cell carcinoma of the head and neck]].		*[[Squamous cell carcinoma of the head and neck]].
	*[[Adenosquamous carcinoma]].		*[[Adenosquamous carcinoma]].

Mitchell: /* Images */ added a case

2016-12-19T14:24:09Z

Images: added a case

← Older revision		Revision as of 14:24, 19 December 2016
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	*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256999/figure/f3-cpath-5-2012-001/ Intermed. grade MEC (nih.gov)].		*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256999/figure/f3-cpath-5-2012-001/ Intermed. grade MEC (nih.gov)].
	*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256999/figure/f4-cpath-5-2012-001/ High-grade MEC (nih.gov)].		*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256999/figure/f4-cpath-5-2012-001/ High-grade MEC (nih.gov)].

			[[File: 5_20985699291686_sl 1.png\|Mucoepidermoid carcinoma of parotid, low grade]]
			[[File: 5_20985699291686_sl 2.png\|Mucoepidermoid carcinoma of parotid, low grade]]
			[[File: 5_20985699291686_sl 3.png\|Mucoepidermoid carcinoma of parotid, low grade]]
			[[File: 5_20985699291686_sl 4.png\|Mucoepidermoid carcinoma of parotid, low grade]]

			Low grade mucoepidermoid carcinoma in left parotid of 51 year old woman. A. Tumor shows blue squamoud differentiation with cystic dilatation. B This focus shows more obvious cyst formation. C. Squamous component with round to spindled cancer cells; note that currently squamous pearls and high grade squamous cancer elements render the tumor a squamous carcinoma, according to Barnes. D. Glandular cell component.

	===Subtypes===		===Subtypes===

Michael: /* IHC */

2015-10-26T20:51:39Z

IHC

← Older revision		Revision as of 20:51, 26 October 2015
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	==IHC==		==IHC==
	*CK7 +ve.		*CK7 +ve.
	*CK20 +ve.		*CK20 -ve.
	*CEA +ve.<ref>{{Cite journal \| last1 = Hassanin \| first1 = MB. \| last2 = Ghosh \| first2 = L. \| last3 = Das \| first3 = AK. \| last4 = Waterhouse \| first4 = JP. \| title = Immunohistochemical and fluorescent microscopic study of histogenesis of salivary mucoepidermoid carcinoma. \| journal = J Oral Pathol Med \| volume = 18 \| issue = 5 \| pages = 291-8 \| month = May \| year = 1989 \| doi = \| PMID = 2475619 }}</ref>		*CEA +ve.<ref>{{Cite journal \| last1 = Hassanin \| first1 = MB. \| last2 = Ghosh \| first2 = L. \| last3 = Das \| first3 = AK. \| last4 = Waterhouse \| first4 = JP. \| title = Immunohistochemical and fluorescent microscopic study of histogenesis of salivary mucoepidermoid carcinoma. \| journal = J Oral Pathol Med \| volume = 18 \| issue = 5 \| pages = 291-8 \| month = May \| year = 1989 \| doi = \| PMID = 2475619 }}</ref>

← Older revision		Revision as of 03:37, 20 March 2018
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	*[[Salivary glands]].		*[[Salivary glands]].
	*[[Squamous cell carcinoma]].		*[[Squamous cell carcinoma]].
			*[[Sclerosing mucoepidermoid carcinoma with eosinophilia]].

	==References==		==References==