Myxopapillary ependymoma - Revision history

Michael: touch

2015-05-02T04:11:34Z

touch

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	{{ Infobox diagnosis		{{ Infobox diagnosis
	\| Name = {{PAGENAME}}		\| Name = {{PAGENAME}}
	\| Image = Myxopapillary_ependymoma_-_very_high_mag.jpg		\| Image = Myxopapillary_ependymoma_-_very_high_mag.jpg
	\| Width =		\| Width =
	\| Caption = Myxopapillary ependymoma. [[HPS stain]].		\| Caption = Myxopapillary ependymoma. [[HPS stain]].

Michael: fix stain decript

2015-04-28T12:56:47Z

fix stain decript

← Older revision		Revision as of 12:56, 28 April 2015
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	\| Image = Myxopapillary_ependymoma_-_very_high_mag.jpg		\| Image = Myxopapillary_ependymoma_-_very_high_mag.jpg
	\| Width =		\| Width =
	\| Caption = Myxopapillary ependymoma. [[~~H&E~~ stain]]		\| Caption = Myxopapillary ependymoma. [[HPS stain]].
	\| Synonyms =		\| Synonyms =
	\| Micro = Papillary tumor cells around vascular myxoid matrix		\| Micro = Papillary tumor cells around vascular myxoid matrix

Jensflorian: /* Images */ touch

2015-04-28T06:02:31Z

Images: touch

← Older revision		Revision as of 06:02, 28 April 2015
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	File:Myxopapillary_ependymoma.jpg \| Mxyopapillary Ependymoma, HE Smear (AFIP)		File:Myxopapillary_ependymoma.jpg \| Mxyopapillary Ependymoma, HE Smear (AFIP)
	File:Myxopapillary_ependymoma_-_intermed_mag.jpg \| Mxyopapillary Ependymoma, low magnification (WC/Nephron)		File:Myxopapillary_ependymoma_-_intermed_mag.jpg \| Mxyopapillary Ependymoma, low magnification (WC/Nephron)
	File:Myxopapillary_ependymoma-HE.jpg \| Intermediate magnification (WC/jensflorian		File:Myxopapillary_ependymoma-HE.jpg \| Intermediate magnification (WC/jensflorian)
	File:Myxopapillary_ependymoma_-_very_high_mag.jpg \| High magnification (WC/Nephron)		File:Myxopapillary_ependymoma_-_very_high_mag.jpg \| High magnification (WC/Nephron)
	File:Myxopapillary_ependymoma_HE_x40.jpg \| Mxyopapillary Ependymoma, vascular sclerosis (WC/jensflorian)		File:Myxopapillary_ependymoma_HE_x40.jpg \| Mxyopapillary Ependymoma, vascular sclerosis (WC/jensflorian)

Michael: tweak

2015-04-27T16:05:28Z

tweak

← Older revision		Revision as of 16:05, 27 April 2015
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	\| Micro = Papillary tumor cells around vascular myxoid matrix		\| Micro = Papillary tumor cells around vascular myxoid matrix
	\| Subtypes = subtype of [[ependymoma]]		\| Subtypes = subtype of [[ependymoma]]
	\| LMDDx = [[~~ependymoma~~]]		\| LMDDx = [[chordoma]], [[myxoid chondrosarcoma]], [[paraganglioma]], papillary [[adenocarcinoma]]
	\| Stains = Alcian blue +ve		\| Stains = Alcian blue +ve
	\| IHC = GFAP +ve		\| IHC = GFAP +ve
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	==Gross==		==Gross==
	*~~soft~~.		*Soft.
	*~~gray~~.		*Gray.
	*~~discrete~~ masses.		*Discrete masses.
	*~~often~~ encapsulated.		*Often encapsulated.
	*Subtotal resected tumors may spread throughout the neuraxis.		*Subtotal resected tumors may spread throughout the neuraxis.

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	</gallery>		</gallery>

	==~~Histology~~==		==Microscopic==
	Features:		Features:
	*Papillary appearance.		*Papillary appearance.
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	*Microcysts.		*Microcysts.
	*Low mitotic activity.		*Low mitotic activity.


	Note:		Note:
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	DDx:		DDx:
	* [[Chordoma]]		* [[Chordoma]].
	* [[Myxoid chondrosarcoma]]		* [[Myxoid chondrosarcoma]].
	* [[Paraganglioma]]		* [[Paraganglioma]].
	* Papillary [[~~Adenocarcinoma~~]]		* Papillary [[adenocarcinoma]].
	~~Images:~~

			===Images===
	<gallery>		<gallery>
	File:Myxopapillary_ependymoma.jpg \| Mxyopapillary Ependymoma, HE Smear (AFIP)		File:Myxopapillary_ependymoma.jpg \| Mxyopapillary Ependymoma, HE Smear (AFIP)
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	==Molecular==		==Molecular==
	* Poorly characterized		* Poorly characterized.
	* No consistent abberations.		* No consistent abberations.


	==See also==		==See also==

Michael: small tweaks

2015-04-27T16:02:23Z

small tweaks

← Older revision		Revision as of 16:02, 27 April 2015
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	\| Synonyms =		\| Synonyms =
	\| Micro = Papillary tumor cells around vascular myxoid matrix		\| Micro = Papillary tumor cells around vascular myxoid matrix
	\| Subtypes =		\| Subtypes = subtype of [[ependymoma]]
	\| LMDDx = [[~~Ependymoma~~]]		\| LMDDx = [[ependymoma]]
	\| Stains = Alcian blue +ve		\| Stains = Alcian blue +ve
	\| IHC = GFAP +ve		\| IHC = GFAP +ve
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	\| Tx =		\| Tx =
	}}		}}

	'''Mxyopapillary Ependymoma''', is a low-grade [[Ependymoma]]. It is nearly always associated with [[cauda equina]] and [[filum terminale]].		'''Mxyopapillary Ependymoma''', is a low-grade [[Ependymoma]]. It is nearly always associated with [[cauda equina]] and [[filum terminale]].

	==General==		==General==
	*Low-grade [[~~Ependymoma~~]] - ''WHO Grade I'' by definition.		*Low-grade [[ependymoma]] - ''WHO Grade I'' by definition.
	*Classically in the spinal cord of adults.		*Classically in the spinal cord of adults.
	* Approx 9-13% of all ependymal tumors.<ref>{{Cite journal \| last1 = Schiffer \| first1 = D. \| last2 = Chiò \| first2 = A. \| last3 = Giordana \| first3 = MT. \| last4 = Migheli \| first4 = A. \| last5 = Palma \| first5 = L. \| last6 = Pollo \| first6 = B. \| last7 = Soffietti \| first7 = R. \| last8 = Tribolo \| first8 = A. \| title = Histologic prognostic factors in ependymoma. \| journal = Childs Nerv Syst \| volume = 7 \| issue = 4 \| pages = 177-82 \| month = Aug \| year = 1991 \| doi = \| PMID = 1933913 }}</ref>		* Approx 9-13% of all ependymal tumors.<ref>{{Cite journal \| last1 = Schiffer \| first1 = D. \| last2 = Chiò \| first2 = A. \| last3 = Giordana \| first3 = MT. \| last4 = Migheli \| first4 = A. \| last5 = Palma \| first5 = L. \| last6 = Pollo \| first6 = B. \| last7 = Soffietti \| first7 = R. \| last8 = Tribolo \| first8 = A. \| title = Histologic prognostic factors in ependymoma. \| journal = Childs Nerv Syst \| volume = 7 \| issue = 4 \| pages = 177-82 \| month = Aug \| year = 1991 \| doi = \| PMID = 1933913 }}</ref>

Michael: fix image

2015-04-27T15:56:47Z

fix image

← Older revision		Revision as of 15:56, 27 April 2015
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	{{ Infobox diagnosis		{{ Infobox diagnosis
	\| Name = {{PAGENAME}}		\| Name = {{PAGENAME}}
	\| Image = ~~File:~~Myxopapillary_ependymoma_-_very_high_mag.jpg		\| Image = Myxopapillary_ependymoma_-_very_high_mag.jpg
	\| Width =		\| Width =
	\| Caption = Myxopapillary ependymoma. [[H&E stain]]		\| Caption = Myxopapillary ependymoma. [[H&E stain]]

Michael: sm fix

2015-04-27T15:55:46Z

sm fix

← Older revision		Revision as of 15:55, 27 April 2015
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	\| Micro = Papillary tumor cells around vascular myxoid matrix		\| Micro = Papillary tumor cells around vascular myxoid matrix
	\| Subtypes =		\| Subtypes =
	\| LMDDx = [[Ependymoma]		\| LMDDx = [[Ependymoma]]
	\| Stains = Alcian blue +ve		\| Stains = Alcian blue +ve
	\| IHC = GFAP +ve		\| IHC = GFAP +ve

Jensflorian: split out + new data added

2015-04-27T14:36:29Z

split out + new data added

← Older revision		Revision as of 14:36, 27 April 2015
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	~~#redirect~~ [[Ependymoma#Myxopapillary_ependymoma]]		{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image = File:Myxopapillary_ependymoma_-_very_high_mag.jpg
			\| Width =
			\| Caption = Myxopapillary ependymoma. [[H&E stain]]
			\| Synonyms =
			\| Micro = Papillary tumor cells around vascular myxoid matrix
			\| Subtypes =
			\| LMDDx = [[Ependymoma]
			\| Stains = Alcian blue +ve
			\| IHC = GFAP +ve
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross =
			\| Grossing =
			\| Site = usually lumbar spinal cord
			\| Assdx =
			\| Syndromes =
			\| Clinicalhx =
			\| Signs =
			\| Symptoms =
			\| Prevalence =
			\| Bloodwork =
			\| Rads =
			\| Endoscopy =
			\| Prognosis = good (WHO Grade I)
			\| Other =
			\| ClinDDx =
			\| Tx =
			}}

			'''Mxyopapillary Ependymoma''', is a low-grade [[Ependymoma]]. It is nearly always associated with [[cauda equina]] and [[filum terminale]].

			==General==
			*Low-grade [[Ependymoma]] - ''WHO Grade I'' by definition.
			*Classically in the spinal cord of adults.
			* Approx 9-13% of all ependymal tumors.<ref>{{Cite journal \| last1 = Schiffer \| first1 = D. \| last2 = Chiò \| first2 = A. \| last3 = Giordana \| first3 = MT. \| last4 = Migheli \| first4 = A. \| last5 = Palma \| first5 = L. \| last6 = Pollo \| first6 = B. \| last7 = Soffietti \| first7 = R. \| last8 = Tribolo \| first8 = A. \| title = Histologic prognostic factors in ependymoma. \| journal = Childs Nerv Syst \| volume = 7 \| issue = 4 \| pages = 177-82 \| month = Aug \| year = 1991 \| doi = \| PMID = 1933913 }}</ref>
			*Associated with back pain.
			*Enhancing mass

			==Gross==
			*soft.
			*gray.
			*discrete masses.
			*often encapsulated.
			*Subtotal resected tumors may spread throughout the neuraxis.

			<gallery>
			File:AFIP405714G-MYXOPAPILLARY EPENDYMOMA.jpg \| Myxopapillary ependymoma in the filum terminale (Dr. E. Michael Scott, Boston, MA).
			File:Myxopapillary_ependymoma_1.jpg \| Mxyopapillary Ependymoma in the spinal cord, cross section (AFIP)
			</gallery>

			==Histology==
			Features:
			*Papillary appearance.
			*Perivascular pseudorosettes:
			**Cuboidal to elongated tumor cells.
			**Radially arranged around vascular cores.
			*Myxoid material surround blood vessels.
			*Microcysts.
			*Low mitotic activity.


			Note:
			Cases with extensive sclerosis may mimic degenerative changes. <ref>{{Cite journal \| last1 = Schittenhelm \| first1 = J. \| last2 = Becker \| first2 = R. \| last3 = Capper \| first3 = D. \| last4 = Meyermann \| first4 = R. \| last5 = Iglesias-Rozas \| first5 = JR. \| last6 = Kaminsky \| first6 = J. \| last7 = Mittelbronn \| first7 = M. \| title = The clinico-surgico-pathological spectrum of myxopapillary ependymomas--report of four unusal cases and review of the literature. \| journal = Clin Neuropathol \| volume = 27 \| issue = 1 \| pages = 21-8 \| month = \| year = \| doi = \| PMID = 18257471 }}</ref>

			DDx:
			* [[Chordoma]]
			* [[Myxoid chondrosarcoma]]
			* [[Paraganglioma]]
			* Papillary [[Adenocarcinoma]]
			Images:

			<gallery>
			File:Myxopapillary_ependymoma.jpg \| Mxyopapillary Ependymoma, HE Smear (AFIP)
			File:Myxopapillary_ependymoma_-_intermed_mag.jpg \| Mxyopapillary Ependymoma, low magnification (WC/Nephron)
			File:Myxopapillary_ependymoma-HE.jpg \| Intermediate magnification (WC/jensflorian
			File:Myxopapillary_ependymoma_-_very_high_mag.jpg \| High magnification (WC/Nephron)
			File:Myxopapillary_ependymoma_HE_x40.jpg \| Mxyopapillary Ependymoma, vascular sclerosis (WC/jensflorian)
			File:Myxopapillary_Ependymoma_Alcian-blue.jpg \| Alcian-blue staining highlighting the mucinous matrix (WC/jensflorian)
			</gallery>
			*[http://commons.wikimedia.org/wiki/File:Myxopapillary_ependymoma_-_high_mag.jpg Myxopapillary ependymoma - high mag. (WC)].
			*[http://careers.bmj.com/article-images/cf0708.f2_default.gif Myxopapillary ependymoma (bmj.com)] - part of [http://careers.bmj.com/careers/advice/view-article.html?id=351 careers.bmj.com article on paediatric pathology].
			*[http://commons.wikimedia.org/wiki/File:Myxopapillary_ependymoma.jpg Myxopapillary ependymoma - cytology (WC)].
			*[http://path.upmc.edu/cases/case626.html Myxopapillary ependymoma - several images (upmc.edu)].

			==IHC==
			* GFAP+ve.
			* S-100+ve.
			* MIB-1 <1%.

			==Molecular==
			* Poorly characterized
			* No consistent abberations.


			==See also==
			*[[Neuropathology tumours]].
			*[[Ependymoma]].

			==References==
			{{Reflist\|2}}

	[[Category:Diagnosis]]		[[Category:Diagnosis]]
			[[Category:Neuropathology tumours]]

Michael: Redirected page to Ependymoma#Myxopapillary ependymoma

2014-12-10T06:28:41Z

Redirected page to Ependymoma#Myxopapillary ependymoma

← Older revision		Revision as of 06:28, 10 December 2014
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	#redirect [[~~Neuropathology_tumours~~#Myxopapillary_ependymoma]]		#redirect [[Ependymoma#Myxopapillary_ependymoma]]

	[[Category:Diagnosis]]		[[Category:Diagnosis]]

Michael: redirect

2012-01-15T00:00:18Z

redirect

New page

#redirect [[Neuropathology_tumours#Myxopapillary_ependymoma]]

[[Category:Diagnosis]]

← Older revision		Revision as of 06:02, 28 April 2015
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	File:Myxopapillary_ependymoma.jpg \| Mxyopapillary Ependymoma, HE Smear (AFIP)		File:Myxopapillary_ependymoma.jpg \| Mxyopapillary Ependymoma, HE Smear (AFIP)
	File:Myxopapillary_ependymoma_-_intermed_mag.jpg \| Mxyopapillary Ependymoma, low magnification (WC/Nephron)		File:Myxopapillary_ependymoma_-_intermed_mag.jpg \| Mxyopapillary Ependymoma, low magnification (WC/Nephron)
	File:Myxopapillary_ependymoma-HE.jpg \| Intermediate magnification (WC/jensflorian		File:Myxopapillary_ependymoma-HE.jpg \| Intermediate magnification (WC/jensflorian)
	File:Myxopapillary_ependymoma_-_very_high_mag.jpg \| High magnification (WC/Nephron)		File:Myxopapillary_ependymoma_-_very_high_mag.jpg \| High magnification (WC/Nephron)
	File:Myxopapillary_ependymoma_HE_x40.jpg \| Mxyopapillary Ependymoma, vascular sclerosis (WC/jensflorian)		File:Myxopapillary_ependymoma_HE_x40.jpg \| Mxyopapillary Ependymoma, vascular sclerosis (WC/jensflorian)