Neurocytoma - Revision history

Jensflorian: /* IHC */ update

2018-07-09T12:07:20Z

IHC: update

← Older revision		Revision as of 12:07, 9 July 2018
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	*Synaptophysin +ve.		*Synaptophysin +ve.
	**Most glial tumour -ve.<ref>URL: [http://path.upmc.edu/cases/case383/dx.html http://path.upmc.edu/cases/case383/dx.html]. Accessed on: 15 January 2012.</ref>		**Most glial tumour -ve.<ref>URL: [http://path.upmc.edu/cases/case383/dx.html http://path.upmc.edu/cases/case383/dx.html]. Accessed on: 15 January 2012.</ref>

			==Molecular==
			*FGFR1-TACC1 fusions common.<ref>{{Cite journal \| last1 = Sievers \| first1 = P. \| last2 = Stichel \| first2 = D. \| last3 = Schrimpf \| first3 = D. \| last4 = Sahm \| first4 = F. \| last5 = Koelsche \| first5 = C. \| last6 = Reuss \| first6 = DE. \| last7 = Wefers \| first7 = AK. \| last8 = Reinhardt \| first8 = A. \| last9 = Huang \| first9 = K. \| title = FGFR1:TACC1 fusion is a frequent event in molecularly defined extraventricular neurocytoma. \| journal = Acta Neuropathol \| volume = \| issue = \| pages = \| month = Jul \| year = 2018 \| doi = 10.1007/s00401-018-1882-3 \| PMID = 29978331 }}</ref>

	==See also==		==See also==

Jensflorian: /* Microscopic */ +details

2018-07-09T12:05:02Z

Microscopic: +details

← Older revision		Revision as of 12:05, 9 July 2018
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	*[[Pineocytoma\|Pineocytomatous]]/neurocytic [[rosette]] = irregular rosette with a large meshwork of fibers (neuropil) at the centre.<ref name=pmid16551982>{{cite journal \|author=Wippold FJ, Perry A \|title=Neuropathology for the neuroradiologist: rosettes and pseudorosettes \|journal=AJNR Am J Neuroradiol \|volume=27 \|issue=3 \|pages=488–92 \|year=2006 \|month=March \|pmid=16551982 \|doi= \|url=}}</ref>		*[[Pineocytoma\|Pineocytomatous]]/neurocytic [[rosette]] = irregular rosette with a large meshwork of fibers (neuropil) at the centre.<ref name=pmid16551982>{{cite journal \|author=Wippold FJ, Perry A \|title=Neuropathology for the neuroradiologist: rosettes and pseudorosettes \|journal=AJNR Am J Neuroradiol \|volume=27 \|issue=3 \|pages=488–92 \|year=2006 \|month=March \|pmid=16551982 \|doi= \|url=}}</ref>
	**Similar to Homer-Wright rosette.		**Similar to Homer-Wright rosette.
			*Monomorphic cells with round nuclei and speckled chromatin.
	*Perinuclear clearing.		*Perinuclear clearing.
			*Ganglion cell differentiation.
	*Well-defined cell borders.		*Well-defined cell borders.
			*Hyalinized vessels.
			*Necrosis absent.

	==IHC==		==IHC==

Jensflorian: /* Images */ +from commons

2018-07-09T12:01:43Z

Images: +from commons

← Older revision		Revision as of 12:01, 9 July 2018
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	===Images===		===Images===
			<gallery>
			File:Neurocytoma_Histopathology_HE.jpg \| Neurocytoma (H&E: WC, Marvin101).
			File:Neurocytoma_NeuN.jpg \| Nuclear NeuN immunoreactivity (WC, Marvin101):
			</gallery>

	www:		www:
	*[http://moon.ouhsc.edu/kfung/jty1/Composites/FNA0IE14-Neurocytoma-Micro.htm Neurocytoma (ouhsc.edu)].		*[http://moon.ouhsc.edu/kfung/jty1/Composites/FNA0IE14-Neurocytoma-Micro.htm Neurocytoma (ouhsc.edu)].

Jensflorian: /* Microscopic */ +ihc

2018-07-09T11:59:20Z

Microscopic: +ihc

← Older revision		Revision as of 11:59, 9 July 2018
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	*Perinuclear clearing.		*Perinuclear clearing.
	*Well-defined cell borders.		*Well-defined cell borders.

			==IHC==
			*MIB-1: Usu. low.
			*Synapthophysin +ve.


	DDx:		DDx:
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	*[[Ganglioglioma]].		*[[Ganglioglioma]].
	*[[Ependymoma]].		*[[Ependymoma]].
			*[[Pilocytic astrocytoma]] (with predominantly oligo-like cell component).
			* Diffuse leptomeningeal gliomeuronal tumour.


	===Images===		===Images===

Michael: /* Microscopic */

2014-12-10T07:54:41Z

Microscopic

← Older revision		Revision as of 07:54, 10 December 2014
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	==Microscopic==		==Microscopic==
	Features:<ref>URL: [http://moon.ouhsc.edu/kfung/jty1/Composites/FNA0IE14-Neurocytoma-Micro.htm http://moon.ouhsc.edu/kfung/jty1/Composites/FNA0IE14-Neurocytoma-Micro.htm]. Accessed on: 12 October 2011.</ref>		Features:<ref>URL: [http://moon.ouhsc.edu/kfung/jty1/Composites/FNA0IE14-Neurocytoma-Micro.htm http://moon.ouhsc.edu/kfung/jty1/Composites/FNA0IE14-Neurocytoma-Micro.htm]. Accessed on: 12 October 2011.</ref>
	*[[Pineocytoma\|Pineocytomatous]]/neurocytic rosette = irregular rosette with a large meshwork of fibers (neuropil) at the centre.<ref name=pmid16551982>{{cite journal \|author=Wippold FJ, Perry A \|title=Neuropathology for the neuroradiologist: rosettes and pseudorosettes \|journal=AJNR Am J Neuroradiol \|volume=27 \|issue=3 \|pages=488–92 \|year=2006 \|month=March \|pmid=16551982 \|doi= \|url=}}</ref>		*[[Pineocytoma\|Pineocytomatous]]/neurocytic [[rosette]] = irregular rosette with a large meshwork of fibers (neuropil) at the centre.<ref name=pmid16551982>{{cite journal \|author=Wippold FJ, Perry A \|title=Neuropathology for the neuroradiologist: rosettes and pseudorosettes \|journal=AJNR Am J Neuroradiol \|volume=27 \|issue=3 \|pages=488–92 \|year=2006 \|month=March \|pmid=16551982 \|doi= \|url=}}</ref>
	**Similar to Homer-Wright rosette.		**Similar to Homer-Wright rosette.
	*Perinuclear clearing.		*Perinuclear clearing.

Michael: /* Microscopic */

2014-12-10T07:53:59Z

Microscopic

← Older revision		Revision as of 07:53, 10 December 2014
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	*[[Ependymoma]].		*[[Ependymoma]].

	===Images====		===Images===
	www:		www:
	*[http://moon.ouhsc.edu/kfung/jty1/Composites/FNA0IE14-Neurocytoma-Micro.htm Neurocytoma (ouhsc.edu)].		*[http://moon.ouhsc.edu/kfung/jty1/Composites/FNA0IE14-Neurocytoma-Micro.htm Neurocytoma (ouhsc.edu)].
	*[http://path.upmc.edu/cases/case383.html Neurocytoma - several images (upmc.edu)].		*[http://path.upmc.edu/cases/case383.html Neurocytoma - several images (upmc.edu)].
	*[http://path.upmc.edu/cases/case561.html Neurocytoma - cerebellar - several images (upmc.edu)].		*[http://path.upmc.edu/cases/case561.html Neurocytoma - cerebellar - several images (upmc.edu)].

	==IHC==		==IHC==
	*Synaptophysin +ve.		*Synaptophysin +ve.

Michael: split out

2014-12-10T06:49:03Z

split out

← Older revision		Revision as of 06:49, 10 December 2014
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	~~#redirect~~ [[~~Neuropathology_tumours#~~Neurocytoma]]		'''Neurocytoma''' is a rare [[neuropathology tumour]].

			==General==
			*Rare.

			==Microscopic==
			Features:<ref>URL: [http://moon.ouhsc.edu/kfung/jty1/Composites/FNA0IE14-Neurocytoma-Micro.htm http://moon.ouhsc.edu/kfung/jty1/Composites/FNA0IE14-Neurocytoma-Micro.htm]. Accessed on: 12 October 2011.</ref>
			*[[Pineocytoma\|Pineocytomatous]]/neurocytic rosette = irregular rosette with a large meshwork of fibers (neuropil) at the centre.<ref name=pmid16551982>{{cite journal \|author=Wippold FJ, Perry A \|title=Neuropathology for the neuroradiologist: rosettes and pseudorosettes \|journal=AJNR Am J Neuroradiol \|volume=27 \|issue=3 \|pages=488–92 \|year=2006 \|month=March \|pmid=16551982 \|doi= \|url=}}</ref>
			**Similar to Homer-Wright rosette.
			*Perinuclear clearing.
			*Well-defined cell borders.

			DDx:
			*[[Oligodendroglioma]] - do not have the characteristic rosettes.
			*[[Ganglioglioma]].
			*[[Ependymoma]].

			===Images====
			www:
			*[http://moon.ouhsc.edu/kfung/jty1/Composites/FNA0IE14-Neurocytoma-Micro.htm Neurocytoma (ouhsc.edu)].
			*[http://path.upmc.edu/cases/case383.html Neurocytoma - several images (upmc.edu)].
			*[http://path.upmc.edu/cases/case561.html Neurocytoma - cerebellar - several images (upmc.edu)].
			==IHC==
			*Synaptophysin +ve.
			**Most glial tumour -ve.<ref>URL: [http://path.upmc.edu/cases/case383/dx.html http://path.upmc.edu/cases/case383/dx.html]. Accessed on: 15 January 2012.</ref>

			==See also==
			*[[Central neurocytoma]].
			*[[Neuropathology tumours]].

			==References==
			{{Reflist\|1}}

	[[Category:Diagnosis]]		[[Category:Diagnosis]]
			[[Category:Neuropathology tumours]]

Michael: +cat.

2011-10-18T03:59:16Z

+cat.

← Older revision		Revision as of 03:59, 18 October 2011
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	#redirect [[Neuropathology_tumours#Neurocytoma]]		#redirect [[Neuropathology_tumours#Neurocytoma]]

			[[Category:Diagnosis]]

Michael: redirect for now

2011-10-12T14:52:18Z

redirect for now

New page

#redirect [[Neuropathology_tumours#Neurocytoma]]