Odontogenic keratocyst - Revision history

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2022-04-21T21:22:19Z

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← Older revision		Revision as of 21:22, 21 April 2022
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	Right Maxillary Sinus Mass, Excision:		Right Maxillary Sinus Mass, Excision:
	- Consistent with odontogenic keratocyst (benign ribbon-like squamous epithelium		- Consistent with odontogenic keratocyst (benign ribbon-like squamous epithelium
	with keratinization separated from the underlying hyaline stroma		with keratinization, separated from the underlying hyaline stroma with cartilage).
	with cartilage).
	- Benign respiratory mucosa with mild inflammation.		- Benign respiratory mucosa with mild inflammation.
	- NEGATIVE for malignancy.		- NEGATIVE for malignancy.

Michael: /* See also */ +SO

2022-04-21T21:21:31Z

Michael at 17:28, 18 March 2019

2019-03-18T17:28:37Z

← Older revision		Revision as of 17:28, 18 March 2019
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	\| rosaicollection = 14023		\| rosaicollection = 14023
	}}		}}
	'''Odontogenic keratocyst''', abbreviated '''OKC''' , is an uncommon [[Odontogenic tumours and cysts\|odontogenic cyst]].		'''Odontogenic keratocyst''', abbreviated '''OKC''', is an uncommon [[Odontogenic tumours and cysts\|odontogenic cyst]].

	It was ~~previously~~ known as '''keratocystic odontogenic tumour''', abbreviated '''KOT'''.<ref name=pmid18353202>{{Cite journal \| last1 = Madras \| first1 = J. \| last2 = Lapointe \| first2 = H. \| title = Keratocystic odontogenic tumour: reclassification of the odontogenic keratocyst from cyst to tumour. \| journal = J Can Dent Assoc \| volume = 74 \| issue = 2 \| pages = 165-165h \| month = Mar \| year = 2008 \| doi = \| PMID = 18353202 }}</ref><ref name="isbn_978-92-832-2438-9">{{Citation \|editor-last=El-Naggar \|editor-first=Adel K \|editor-last2=Chan \|editor-first2=John KC \|editor-last3=Grandis \|editor-first3=Jennifer R \|editor-last4=Takata \|editor-first4=Takashi \|editor-last5=Slootweg \|editor-first5=Pieter J \|year=2017 \|title=WHO Classification of Head and Neck Tumours \|edition= 4th \|volume=9 \|series=WHO/IARC Classification of Tumours \|publisher=IARC Press \|location=Lyon, France \|url=http://publications.iarc.fr/Book-And-Report-Series/Who-Iarc-Classification-Of-Tumours/Who-Classification-Of-Head-And-Neck-Tumours-2017 \|isbn=978-92-832-2438-9 \|oclc= \|lccn= \|postscript=.}}</ref>		It was known as '''keratocystic odontogenic tumour''', abbreviated '''KOT''', from 2005 to 2017.<ref name=pmid18353202>{{Cite journal \| last1 = Madras \| first1 = J. \| last2 = Lapointe \| first2 = H. \| title = Keratocystic odontogenic tumour: reclassification of the odontogenic keratocyst from cyst to tumour. \| journal = J Can Dent Assoc \| volume = 74 \| issue = 2 \| pages = 165-165h \| month = Mar \| year = 2008 \| doi = \| PMID = 18353202 }}</ref><ref name="isbn_978-92-832-2438-9">{{Citation \|editor-last=El-Naggar \|editor-first=Adel K \|editor-last2=Chan \|editor-first2=John KC \|editor-last3=Grandis \|editor-first3=Jennifer R \|editor-last4=Takata \|editor-first4=Takashi \|editor-last5=Slootweg \|editor-first5=Pieter J \|year=2017 \|title=WHO Classification of Head and Neck Tumours \|edition= 4th \|volume=9 \|series=WHO/IARC Classification of Tumours \|publisher=IARC Press \|location=Lyon, France \|url=http://publications.iarc.fr/Book-And-Report-Series/Who-Iarc-Classification-Of-Tumours/Who-Classification-Of-Head-And-Neck-Tumours-2017 \|isbn=978-92-832-2438-9 \|oclc= \|lccn= \|postscript=.}}</ref>
	==General==		==General==
	*May be associated with ''[[nevoid basal cell carcinoma syndrome]]''.		*May be associated with ''[[nevoid basal cell carcinoma syndrome]]''.

Michael: update

2019-03-18T17:27:31Z

update

← Older revision		Revision as of 17:27, 18 March 2019
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	~~#redirect~~ [[Keratocystic odontogenic tumour]]		{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image = Keratocystic_odontogenic_tumour_-_intermed_mag.jpg
			\| Width =
			\| Caption = Keratocystic odontogenic tumour. [[H&E stain]].
			\| Synonyms = odontogenic keratocyst (old term)
			\| Micro = stratified epithelium with "ribbon-like appearance" with palisaded basal cell layer, parakeratosis, artefactual separation of epithelium from the basement membrane
			\| Subtypes =
			\| LMDDx = odontogenic cyst ([[dentigerous cyst]]), [[squamous cell carcinoma]]
			\| Stains =
			\| IHC =
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross =
			\| Grossing =
			\| Site = usually mandible - see ''[[odontogenic tumours and cysts]]''
			\| Assdx =
			\| Syndromes = [[nevoid basal cell carcinoma syndrome]]
			\| Clinicalhx =
			\| Signs = mass lesion
			\| Symptoms =
			\| Prevalence = uncommon
			\| Bloodwork =
			\| Rads =
			\| Endoscopy =
			\| Prognosis =
			\| Other =
			\| ClinDDx = [[ameloblastoma]]
			\| Tx =
			}}
			{{ Infobox external links
			\| Name = {{PAGENAME}}
			\| EHVSC = 10179
			\| EHVSC_mult = {{EHVSC2\|10178}}
			\| pathprotocols =
			\| wikipedia = keratocystic odontogenic tumour
			\| pathoutlines = {{Pathologyoutlines\|topic/mandiblemaxillakeratocyst}}
			\| rosaicollection = 14023
			}}
			'''Odontogenic keratocyst''', abbreviated '''OKC''' , is an uncommon [[Odontogenic tumours and cysts\|odontogenic cyst]].

			It was previously known as '''keratocystic odontogenic tumour''', abbreviated '''KOT'''.<ref name=pmid18353202>{{Cite journal \| last1 = Madras \| first1 = J. \| last2 = Lapointe \| first2 = H. \| title = Keratocystic odontogenic tumour: reclassification of the odontogenic keratocyst from cyst to tumour. \| journal = J Can Dent Assoc \| volume = 74 \| issue = 2 \| pages = 165-165h \| month = Mar \| year = 2008 \| doi = \| PMID = 18353202 }}</ref><ref name="isbn_978-92-832-2438-9">{{Citation \|editor-last=El-Naggar \|editor-first=Adel K \|editor-last2=Chan \|editor-first2=John KC \|editor-last3=Grandis \|editor-first3=Jennifer R \|editor-last4=Takata \|editor-first4=Takashi \|editor-last5=Slootweg \|editor-first5=Pieter J \|year=2017 \|title=WHO Classification of Head and Neck Tumours \|edition= 4th \|volume=9 \|series=WHO/IARC Classification of Tumours \|publisher=IARC Press \|location=Lyon, France \|url=http://publications.iarc.fr/Book-And-Report-Series/Who-Iarc-Classification-Of-Tumours/Who-Classification-Of-Head-And-Neck-Tumours-2017 \|isbn=978-92-832-2438-9 \|oclc= \|lccn= \|postscript=.}}</ref>
			==General==
			*May be associated with ''[[nevoid basal cell carcinoma syndrome]]''.
			*Very rarely transforms to a [[squamous cell carcinoma]].<ref name=pmid21493332>{{Cite journal \| last1 = Lee \| first1 = JW. \| last2 = Gates \| first2 = R. \| last3 = Wignall \| first3 = A. \| title = Squamous cell carcinoma arising from a keratocystic odontogenic tumor. \| journal = Otolaryngol Head Neck Surg \| volume = 145 \| issue = 2 \| pages = 356-7 \| month = Aug \| year = 2011 \| doi = 10.1177/0194599811399270 \| PMID = 21493332 }}</ref><ref name=pmid23374486>{{Cite journal \| last1 = Tan \| first1 = B. \| last2 = Yan \| first2 = TS. \| last3 = Shermin \| first3 = L. \| last4 = Teck \| first4 = KC. \| last5 = Yoke \| first5 = PC. \| last6 = Goh \| first6 = C. \| last7 = Balakrishnan \| first7 = A. \| title = Malignant transformation of keratocystic odontogenic tumor: Two case reports. \| journal = Am J Otolaryngol \| volume = 34 \| issue = 4 \| pages = 357-61 \| month = \| year = \| doi = 10.1016/j.amjoto.2013.01.002 \| PMID = 23374486 }}</ref>

			===Clinical===
			Features:<ref name=pmid17928730>{{Cite journal \| last1 = Habibi \| first1 = A. \| last2 = Saghravanian \| first2 = N. \| last3 = Habibi \| first3 = M. \| last4 = Mellati \| first4 = E. \| last5 = Habibi \| first5 = M. \| title = Keratocystic odontogenic tumor: a 10-year retrospective study of 83 cases in an Iranian population. \| journal = J Oral Sci \| volume = 49 \| issue = 3 \| pages = 229-35 \| month = Sep \| year = 2007 \| doi = \| PMID = 17928730 }}</ref>
			*Most common presentation: swelling.

			==Gross==
			*Location: usually mandible.
			*May mimic [[ameloblastoma]] radiologically.

			==Microscopic==
			Features: <ref>Thompson LDR. Head and neck pathology - (Foundations in diagnostic pathology). Goldblum JR, Ed.. Churchill Livingstone. 2006. ISBN 0-443-06960-3.</ref>
			*Stratified epithelium (resembling squamous epithelium) with:
			**"Ribbon-like appearance" - '''important'''.
			***Typically 8-10 cell layers thick - with relatively uniform thickness.
			***Lacks rete ridges.
			**Palisaded basal cell layer.
			*Parakeratosis (keratinized cells with nuclei) - '''key feature'''.
			*Artefactual separation of epithelium from the basement membrane.

			DDx:
			*Odontogenic cyst.
			**Orthokeratinized odontogenic cyst<ref name=pmid21062939>{{Cite journal \| last1 = Macdonald-Jankowski \| first1 = DS. \| title = Orthokeratinized odontogenic cyst: a systematic review. \| journal = Dentomaxillofac Radiol \| volume = 39 \| issue = 8 \| pages = 455-67 \| month = Dec \| year = 2010 \| doi = 10.1259/dmfr/19728573 \| PMID = }}</ref> - usu. [[dentigerous cyst]] - has [[orthokeratosis]] instead of [[parakeratosis]].
			***Orthokeratosis = keratinized cells no nuclei; parakeratosis = keratinized cell with nuclei.

			===Images===
			<gallery>
			Image:Keratocystic_odontogenic_tumour_-_2_-_intermed_mag.jpg \| KOT - intermed. mag. (WC)
			Image:Keratocystic_odontogenic_tumour_-_2_-_very_high_mag.jpg \| KOT - very high mag. (WC)
			Image:Keratocystic_odontogenic_tumour_-_intermed_mag.jpg KOT - another case - intermed. mag. (WC)]
			Image:Keratocystic_odontogenic_tumour1.jpg \| KOT - poor quality. (WC)
			Image:Keratocystic_odontogenic_tumour2.jpg \| KOT - showing artefactual clefting - poor quality. (WC)
			</gallery>
			www:
			*[http://ars.els-cdn.com/content/image/1-s2.0-S0968605305000992-gr5.jpg KOT (els-cdn.com)].<ref>URL: [http://www.sciencedirect.com/science/article/pii/S0968605305000992#fig5 http://www.sciencedirect.com/science/article/pii/S0968605305000992#fig5]. Accessed on: 11 March 2013.</ref>

			==See also==
			*[[Odontogenic tumours and cysts]].
			*[[Head and neck pathology]].

			==References==
			{{Reflist\|2}}

			[[Category:Diagnosis]]
			[[Category:Odontogenic tumours and cysts]]

Michael: fix redirect

2013-07-26T18:32:32Z

fix redirect

← Older revision		Revision as of 18:32, 26 July 2013
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	#redirect [[~~Keratocytic~~ odontogenic tumour]]		#redirect [[Keratocystic odontogenic tumour]]

Michael: redirect

2013-07-26T18:32:19Z

redirect

New page

#redirect [[Keratocytic odontogenic tumour]]

← Older revision		Revision as of 21:21, 21 April 2022
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	www:		www:
	*[http://ars.els-cdn.com/content/image/1-s2.0-S0968605305000992-gr5.jpg KOT (els-cdn.com)].<ref>URL: [http://www.sciencedirect.com/science/article/pii/S0968605305000992#fig5 http://www.sciencedirect.com/science/article/pii/S0968605305000992#fig5]. Accessed on: 11 March 2013.</ref>		*[http://ars.els-cdn.com/content/image/1-s2.0-S0968605305000992-gr5.jpg KOT (els-cdn.com)].<ref>URL: [http://www.sciencedirect.com/science/article/pii/S0968605305000992#fig5 http://www.sciencedirect.com/science/article/pii/S0968605305000992#fig5]. Accessed on: 11 March 2013.</ref>

			==Sign out==
			<pre>
			Right Maxillary Sinus Mass, Excision:
			- Consistent with odontogenic keratocyst (benign ribbon-like squamous epithelium
			with keratinization separated from the underlying hyaline stroma
			with cartilage).
			- Benign respiratory mucosa with mild inflammation.
			- NEGATIVE for malignancy.
			</pre>

	==See also==		==See also==