Oncometabolite - Revision history

Michael: /* Examples */ tweak a bit, leiomyoma not cancer

2017-03-22T18:12:30Z

Examples: tweak a bit, leiomyoma not cancer

← Older revision		Revision as of 18:12, 22 March 2017
Line 7:		Line 7:
	\|-		\|-
	\| fumarate hydratase (FH)		\| fumarate hydratase (FH)
	\| [[~~Leiomyoma~~]]<ref name=pmid22866264>{{Cite journal \| last1 = Yang \| first1 = M. \| last2 = Soga \| first2 = T. \| last3 = Pollard \| first3 = PJ. \| last4 = Adam \| first4 = J. \| title = The emerging role of fumarate as an oncometabolite. \| journal = Front Oncol \| volume = 2 \| issue = \| pages = 85 \| month = \| year = 2012 \| doi = 10.3389/fonc.2012.00085 \| PMID = 22866264 }}</ref>		\| [[Hereditary leiomyomatosis and renal cell carcinoma syndrome-associated renal cell carcinoma\|HLRCC syndrome-associated RCC]]<ref name=pmid22866264>{{Cite journal \| last1 = Yang \| first1 = M. \| last2 = Soga \| first2 = T. \| last3 = Pollard \| first3 = PJ. \| last4 = Adam \| first4 = J. \| title = The emerging role of fumarate as an oncometabolite. \| journal = Front Oncol \| volume = 2 \| issue = \| pages = 85 \| month = \| year = 2012 \| doi = 10.3389/fonc.2012.00085 \| PMID = 22866264 }}</ref>
	\|-		\|-
	\| [[IDH mutation\|isocitrate dehydrogenase]] (IDH)		\| [[IDH mutation\|isocitrate dehydrogenase]] (IDH)

Michael: /* Examples */

2017-03-22T18:08:02Z

Examples

← Older revision		Revision as of 18:08, 22 March 2017
Line 7:		Line 7:
	\|-		\|-
	\| fumarate hydratase (FH)		\| fumarate hydratase (FH)
	\| [[Leiomyoma]]<ref>{{Cite journal \| last1 = Yang \| first1 = M. \| last2 = Soga \| first2 = T. \| last3 = Pollard \| first3 = PJ. \| last4 = Adam \| first4 = J. \| title = The emerging role of fumarate as an oncometabolite. \| journal = Front Oncol \| volume = 2 \| issue = \| pages = 85 \| month = \| year = 2012 \| doi = 10.3389/fonc.2012.00085 \| PMID = 22866264 }}</ref>		\| [[Leiomyoma]]<ref name=pmid22866264>{{Cite journal \| last1 = Yang \| first1 = M. \| last2 = Soga \| first2 = T. \| last3 = Pollard \| first3 = PJ. \| last4 = Adam \| first4 = J. \| title = The emerging role of fumarate as an oncometabolite. \| journal = Front Oncol \| volume = 2 \| issue = \| pages = 85 \| month = \| year = 2012 \| doi = 10.3389/fonc.2012.00085 \| PMID = 22866264 }}</ref>
	\|-		\|-
	\| [[IDH mutation\|isocitrate dehydrogenase]] (IDH)		\| [[IDH mutation\|isocitrate dehydrogenase]] (IDH)

Michael: /* Examples */

2017-03-22T18:06:55Z

Examples

← Older revision		Revision as of 18:06, 22 March 2017
Line 12:		Line 12:
	\| [[Astrocytoma]], [[Oligodendroglioma]]<ref>{{Cite journal \| last1 = Hartmann \| first1 = C. \| last2 = Hentschel \| first2 = B. \| last3 = Wick \| first3 = W. \| last4 = Capper \| first4 = D. \| last5 = Felsberg \| first5 = J. \| last6 = Simon \| first6 = M. \| last7 = Westphal \| first7 = M. \| last8 = Schackert \| first8 = G. \| last9 = Meyermann \| first9 = R. \| title = Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas. \| journal = Acta Neuropathol \| volume = 120 \| issue = 6 \| pages = 707-18 \| month = Dec \| year = 2010 \| doi = 10.1007/s00401-010-0781-z \| PMID = 21088844 }}</ref>		\| [[Astrocytoma]], [[Oligodendroglioma]]<ref>{{Cite journal \| last1 = Hartmann \| first1 = C. \| last2 = Hentschel \| first2 = B. \| last3 = Wick \| first3 = W. \| last4 = Capper \| first4 = D. \| last5 = Felsberg \| first5 = J. \| last6 = Simon \| first6 = M. \| last7 = Westphal \| first7 = M. \| last8 = Schackert \| first8 = G. \| last9 = Meyermann \| first9 = R. \| title = Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas. \| journal = Acta Neuropathol \| volume = 120 \| issue = 6 \| pages = 707-18 \| month = Dec \| year = 2010 \| doi = 10.1007/s00401-010-0781-z \| PMID = 21088844 }}</ref>
	\|-		\|-
	\| [[SDH]]		\| [[Succinate dehydrogenase\|SDH]]
	\| [[Paraganglioma]]<ref>{{Cite journal \| last1 = Baysal \| first1 = BE. \| last2 = Ferrell \| first2 = RE. \| last3 = Willett-Brozick \| first3 = JE. \| last4 = Lawrence \| first4 = EC. \| last5 = Myssiorek \| first5 = D. \| last6 = Bosch \| first6 = A. \| last7 = van der Mey \| first7 = A. \| last8 = Taschner \| first8 = PE. \| last9 = Rubinstein \| first9 = WS. \| title = Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma. \| journal = Science \| volume = 287 \| issue = 5454 \| pages = 848-51 \| month = Feb \| year = 2000 \| doi = \| PMID = 10657297 }}</ref>		\| [[Paraganglioma]]<ref>{{Cite journal \| last1 = Baysal \| first1 = BE. \| last2 = Ferrell \| first2 = RE. \| last3 = Willett-Brozick \| first3 = JE. \| last4 = Lawrence \| first4 = EC. \| last5 = Myssiorek \| first5 = D. \| last6 = Bosch \| first6 = A. \| last7 = van der Mey \| first7 = A. \| last8 = Taschner \| first8 = PE. \| last9 = Rubinstein \| first9 = WS. \| title = Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma. \| journal = Science \| volume = 287 \| issue = 5454 \| pages = 848-51 \| month = Feb \| year = 2000 \| doi = \| PMID = 10657297 }}</ref>
	\|}		\|}

Michael: /* Examples */ wikify

2017-03-22T18:06:30Z

Examples: wikify

← Older revision		Revision as of 18:06, 22 March 2017
Line 12:		Line 12:
	\| [[Astrocytoma]], [[Oligodendroglioma]]<ref>{{Cite journal \| last1 = Hartmann \| first1 = C. \| last2 = Hentschel \| first2 = B. \| last3 = Wick \| first3 = W. \| last4 = Capper \| first4 = D. \| last5 = Felsberg \| first5 = J. \| last6 = Simon \| first6 = M. \| last7 = Westphal \| first7 = M. \| last8 = Schackert \| first8 = G. \| last9 = Meyermann \| first9 = R. \| title = Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas. \| journal = Acta Neuropathol \| volume = 120 \| issue = 6 \| pages = 707-18 \| month = Dec \| year = 2010 \| doi = 10.1007/s00401-010-0781-z \| PMID = 21088844 }}</ref>		\| [[Astrocytoma]], [[Oligodendroglioma]]<ref>{{Cite journal \| last1 = Hartmann \| first1 = C. \| last2 = Hentschel \| first2 = B. \| last3 = Wick \| first3 = W. \| last4 = Capper \| first4 = D. \| last5 = Felsberg \| first5 = J. \| last6 = Simon \| first6 = M. \| last7 = Westphal \| first7 = M. \| last8 = Schackert \| first8 = G. \| last9 = Meyermann \| first9 = R. \| title = Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas. \| journal = Acta Neuropathol \| volume = 120 \| issue = 6 \| pages = 707-18 \| month = Dec \| year = 2010 \| doi = 10.1007/s00401-010-0781-z \| PMID = 21088844 }}</ref>
	\|-		\|-
	\| SDH		\| [[SDH]]
	\| [[Paraganglioma]]<ref>{{Cite journal \| last1 = Baysal \| first1 = BE. \| last2 = Ferrell \| first2 = RE. \| last3 = Willett-Brozick \| first3 = JE. \| last4 = Lawrence \| first4 = EC. \| last5 = Myssiorek \| first5 = D. \| last6 = Bosch \| first6 = A. \| last7 = van der Mey \| first7 = A. \| last8 = Taschner \| first8 = PE. \| last9 = Rubinstein \| first9 = WS. \| title = Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma. \| journal = Science \| volume = 287 \| issue = 5454 \| pages = 848-51 \| month = Feb \| year = 2000 \| doi = \| PMID = 10657297 }}</ref>		\| [[Paraganglioma]]<ref>{{Cite journal \| last1 = Baysal \| first1 = BE. \| last2 = Ferrell \| first2 = RE. \| last3 = Willett-Brozick \| first3 = JE. \| last4 = Lawrence \| first4 = EC. \| last5 = Myssiorek \| first5 = D. \| last6 = Bosch \| first6 = A. \| last7 = van der Mey \| first7 = A. \| last8 = Taschner \| first8 = PE. \| last9 = Rubinstein \| first9 = WS. \| title = Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma. \| journal = Science \| volume = 287 \| issue = 5454 \| pages = 848-51 \| month = Feb \| year = 2000 \| doi = \| PMID = 10657297 }}</ref>
	\|}		\|}

Jensflorian: created

2017-03-22T13:38:35Z

created

New page

An '''oncometabolite''' is a [[cancer]] associated protein, often a mutated enzyme.

==Examples==
{| class="wikitable sortable"
! Gene
! Cancer
|-
| fumarate hydratase (FH)
| [[Leiomyoma]]<ref>{{Cite journal | last1 = Yang | first1 = M. | last2 = Soga | first2 = T. | last3 = Pollard | first3 = PJ. | last4 = Adam | first4 = J. | title = The emerging role of fumarate as an oncometabolite. | journal = Front Oncol | volume = 2 | issue = | pages = 85 | month = | year = 2012 | doi = 10.3389/fonc.2012.00085 | PMID = 22866264 }}</ref>
|-
| [[IDH mutation|isocitrate dehydrogenase]] (IDH)
| [[Astrocytoma]], [[Oligodendroglioma]]<ref>{{Cite journal | last1 = Hartmann | first1 = C. | last2 = Hentschel | first2 = B. | last3 = Wick | first3 = W. | last4 = Capper | first4 = D. | last5 = Felsberg | first5 = J. | last6 = Simon | first6 = M. | last7 = Westphal | first7 = M. | last8 = Schackert | first8 = G. | last9 = Meyermann | first9 = R. | title = Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas. | journal = Acta Neuropathol | volume = 120 | issue = 6 | pages = 707-18 | month = Dec | year = 2010 | doi = 10.1007/s00401-010-0781-z | PMID = 21088844 }}</ref>
|-
| SDH
| [[Paraganglioma]]<ref>{{Cite journal | last1 = Baysal | first1 = BE. | last2 = Ferrell | first2 = RE. | last3 = Willett-Brozick | first3 = JE. | last4 = Lawrence | first4 = EC. | last5 = Myssiorek | first5 = D. | last6 = Bosch | first6 = A. | last7 = van der Mey | first7 = A. | last8 = Taschner | first8 = PE. | last9 = Rubinstein | first9 = WS. | title = Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma. | journal = Science | volume = 287 | issue = 5454 | pages = 848-51 | month = Feb | year = 2000 | doi = | PMID = 10657297 }}</ref>
|}

==See also==
*[[Tumour suppressor gene]].
*[[Oncogene]]
*[[Molecular pathology]].

==References==
{{Reflist|2}}

[[Category:Molecular pathology]]