Papillary adenoma of the kidney - Revision history

Michael: /* General */

2016-06-23T12:57:49Z

General

← Older revision		Revision as of 12:57, 23 June 2016
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	Note:		Note:
	*In the kidney, the concept of ''[[adenoma]]'' only exists for papillary lesions that are [[papillary RCC]]-like. Small lesions that [[chromophobe RCC]]-like ~~and~~ [[clear cell RCC]]-like are carcinomas.<ref name=pmid18846240/>		*In the kidney, the concept of ''[[adenoma]]'' only exists for papillary lesions that are [[papillary RCC]]-like. Small lesions that are [[chromophobe RCC]]-like or [[clear cell RCC]]-like are carcinomas.<ref name=pmid18846240/>

	==Gross==		==Gross==

Michael: /* IHC */

2016-06-23T12:56:35Z

IHC

← Older revision		Revision as of 12:56, 23 June 2016
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	==IHC==		==IHC==
			*CK7 +ve.
	*AMACR +ve.<ref name=pmid17056094/>		*AMACR +ve.<ref name=pmid17056094/>

Michael at 12:56, 23 June 2016

2016-06-23T12:56:20Z

← Older revision		Revision as of 12:56, 23 June 2016
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	Note:		Note:
	*In the kidney, the concept of ''[[adenoma]]'' only exists for papillary lesions that are [[papillary RCC]]-like. Small lesions that [[chromophobe RCC]]-like and [[clear cell RCC]]-like are carcinomas.<ref name=pmid18846240>{{Cite journal \| last1 = Algaba \| first1 = F. \| title = Renal adenomas: pathological differential diagnosis with malignant tumors. \| journal = Adv Urol \| volume = \| issue = \| pages = 974848 \| month = \| year = 2008 \| doi = 10.1155/~~2008/974848 \| PMID = 18846240 }}</ref~~>		*In the kidney, the concept of ''[[adenoma]]'' only exists for papillary lesions that are [[papillary RCC]]-like. Small lesions that [[chromophobe RCC]]-like and [[clear cell RCC]]-like are carcinomas.<ref name=pmid18846240/>

	==Gross==		==Gross==

Michael: /* General */

2016-06-23T12:48:51Z

General

← Older revision		Revision as of 12:48, 23 June 2016
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	**Stains like PaRCC.		**Stains like PaRCC.
	**Found with an increased frequency within the content of PaRCC.		**Found with an increased frequency within the content of PaRCC.

			Note:
			*In the kidney, the concept of ''[[adenoma]]'' only exists for papillary lesions that are [[papillary RCC]]-like. Small lesions that [[chromophobe RCC]]-like and [[clear cell RCC]]-like are carcinomas.<ref name=pmid18846240>{{Cite journal \| last1 = Algaba \| first1 = F. \| title = Renal adenomas: pathological differential diagnosis with malignant tumors. \| journal = Adv Urol \| volume = \| issue = \| pages = 974848 \| month = \| year = 2008 \| doi = 10.1155/2008/974848 \| PMID = 18846240 }}</ref>

	==Gross==		==Gross==

Michael at 01:20, 14 June 2016

2016-06-14T01:20:20Z

← Older revision		Revision as of 01:20, 14 June 2016
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	\| Caption = Papillary adenoma. [[H&E stain]].		\| Caption = Papillary adenoma. [[H&E stain]].
	\| Synonyms = papillary adenoma, renal papillary adenoma		\| Synonyms = papillary adenoma, renal papillary adenoma
	\| Micro = papillae typically with foam cells, +/-psammoma bodies, low [[ISUP grade]], ''must'' be <=1.5 cm		\| Micro = papillae typically with foam cells, +/-psammoma bodies, low [[ISUP nucleolar grade]], ''must'' be <=1.5 cm
	\| Subtypes =		\| Subtypes =
	\| LMDDx = [[papillary renal cell carcinoma]], [[metanephric adenoma]]		\| LMDDx = [[papillary renal cell carcinoma]], [[metanephric adenoma]]

Michael: /* Microscopic */

2016-06-14T01:19:53Z

Microscopic

← Older revision		Revision as of 01:19, 14 June 2016
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	#''Must'' be <=1.5 cm as per 2016 WHO classification.<ref name=pmid26935559>{{Cite journal \| last1 = Moch \| first1 = H. \| last2 = Cubilla \| first2 = AL. \| last3 = Humphrey \| first3 = PA. \| last4 = Reuter \| first4 = VE. \| last5 = Ulbright \| first5 = TM. \| title = The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs-Part A: Renal, Penile, and Testicular Tumours. \| journal = Eur Urol \| volume = \| issue = \| pages = \| month = Feb \| year = 2016 \| doi = 10.1016/j.eururo.2016.02.029 \| PMID = 26935559 }}</ref>		#''Must'' be <=1.5 cm as per 2016 WHO classification.<ref name=pmid26935559>{{Cite journal \| last1 = Moch \| first1 = H. \| last2 = Cubilla \| first2 = AL. \| last3 = Humphrey \| first3 = PA. \| last4 = Reuter \| first4 = VE. \| last5 = Ulbright \| first5 = TM. \| title = The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs-Part A: Renal, Penile, and Testicular Tumours. \| journal = Eur Urol \| volume = \| issue = \| pages = \| month = Feb \| year = 2016 \| doi = 10.1016/j.eururo.2016.02.029 \| PMID = 26935559 }}</ref>
	#*[[Diagnostic size cutoff]] - larger lesions are ''papillary renal cell carcinoma''.		#*[[Diagnostic size cutoff]] - larger lesions are ''papillary renal cell carcinoma''.

			Note:
			*The size cut-off used to be <=0.5 cm.<ref name=pmid26935559/><ref name=Ref_GUP288>{{Ref GUP\|288}}</ref><ref name=pmid18846240>{{Cite journal \| last1 = Algaba \| first1 = F. \| title = Renal adenomas: pathological differential diagnosis with malignant tumors. \| journal = Adv Urol \| volume = \| issue = \| pages = 974848 \| month = \| year = 2008 \| doi = 10.1155/2008/974848 \| PMID = 18846240 \| PMC = 2563151 \| URL = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2563151/?tool=pubmed }}</ref>

	DDx:		DDx:
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	*[[Metanephric adenoma]].		*[[Metanephric adenoma]].

	~~Note:~~
	*The size cut-off used to be <=0.5 cm.<ref name=pmid26935559/><ref name=Ref_GUP288>{{Ref GUP\|288}}</ref><ref name=pmid18846240>{{Cite journal \| last1 = Algaba \| first1 = F. \| title = Renal adenomas: pathological differential diagnosis with malignant tumors. \| journal = Adv Urol \| volume = \| issue = \| pages = 974848 \| month = \| year = 2008 \| doi = 10.1155/2008/974848 \| PMID = 18846240 \| PMC = 2563151 \| URL = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2563151/?tool=pubmed }}</ref>
	===Images===		===Images===
	<gallery>		<gallery>

Michael at 03:33, 27 May 2016

2016-05-27T03:33:34Z

← Older revision		Revision as of 03:33, 27 May 2016
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	\| Caption = Papillary adenoma. [[H&E stain]].		\| Caption = Papillary adenoma. [[H&E stain]].
	\| Synonyms = papillary adenoma, renal papillary adenoma		\| Synonyms = papillary adenoma, renal papillary adenoma
	\| Micro = papillae typically with foam cells, +/-psammoma bodies, ~~nuclei usu.~~ low grade, '''must''' be <=1.5 cm		\| Micro = papillae typically with foam cells, +/-psammoma bodies, low [[ISUP grade]], ''must'' be <=1.5 cm
	\| Subtypes =		\| Subtypes =
	\| LMDDx = [[papillary renal cell carcinoma]], [[metanephric adenoma]]		\| LMDDx = [[papillary renal cell carcinoma]], [[metanephric adenoma]]
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	Features:		Features:
	#Histomorphology of ''[[papillary renal cell carcinoma]]'' with low [[ISUP nucleolar grade]] (grade 1 or 2).		#Histomorphology of ''[[papillary renal cell carcinoma]]'' with low [[ISUP nucleolar grade]] (grade 1 or 2).
	#~~'''~~''Must~~'''~~'' be <=1.5 cm as per 2016 WHO classification.<ref name=pmid26935559>{{Cite journal \| last1 = Moch \| first1 = H. \| last2 = Cubilla \| first2 = AL. \| last3 = Humphrey \| first3 = PA. \| last4 = Reuter \| first4 = VE. \| last5 = Ulbright \| first5 = TM. \| title = The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs-Part A: Renal, Penile, and Testicular Tumours. \| journal = Eur Urol \| volume = \| issue = \| pages = \| month = Feb \| year = 2016 \| doi = 10.1016/j.eururo.2016.02.029 \| PMID = 26935559 }}</ref>		#''Must'' be <=1.5 cm as per 2016 WHO classification.<ref name=pmid26935559>{{Cite journal \| last1 = Moch \| first1 = H. \| last2 = Cubilla \| first2 = AL. \| last3 = Humphrey \| first3 = PA. \| last4 = Reuter \| first4 = VE. \| last5 = Ulbright \| first5 = TM. \| title = The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs-Part A: Renal, Penile, and Testicular Tumours. \| journal = Eur Urol \| volume = \| issue = \| pages = \| month = Feb \| year = 2016 \| doi = 10.1016/j.eururo.2016.02.029 \| PMID = 26935559 }}</ref>
	#*[[Diagnostic size cutoff]] - larger lesions are ''papillary renal cell carcinoma''.		#*[[Diagnostic size cutoff]] - larger lesions are ''papillary renal cell carcinoma''.

Michael at 03:31, 27 May 2016

2016-05-27T03:31:57Z

← Older revision		Revision as of 03:31, 27 May 2016
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	\| Caption = Papillary adenoma. [[H&E stain]].		\| Caption = Papillary adenoma. [[H&E stain]].
	\| Synonyms = papillary adenoma, renal papillary adenoma		\| Synonyms = papillary adenoma, renal papillary adenoma
	\| Micro = papillae typically with foam cells, +/-psammoma bodies, nuclei usu. low grade, '''must''' be <=0.5 cm		\| Micro = papillae typically with foam cells, +/-psammoma bodies, nuclei usu. low grade, '''must''' be <=1.5 cm
	\| Subtypes =		\| Subtypes =
	\| LMDDx = [[papillary renal cell carcinoma]], [[metanephric adenoma]]		\| LMDDx = [[papillary renal cell carcinoma]], [[metanephric adenoma]]
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	==Microscopic==		==Microscopic==
	Features:		Features:
	#Histomorphology of ''[[papillary renal cell carcinoma]]''.		#Histomorphology of ''[[papillary renal cell carcinoma]]'' with low [[ISUP nucleolar grade]] (grade 1 or 2).
	#'''''Must''''' be <=0.5 cm.<ref name=~~Ref_GUP288>{{Ref GUP\|288}}</ref><ref name=pmid18846240~~>{{Cite journal \| last1 = ~~Algaba~~ \| first1 = F. \| title = Renal ~~adenomas: pathological differential diagnosis with malignant tumors~~. \| journal = ~~Adv~~ Urol \| volume = \| issue = \| pages = ~~974848~~ \| month = \| year = ~~2008~~ \| doi = 10.~~1155~~/~~2008/974848 \| PMID = 18846240 \| PMC = 2563151 \| URL = http://www~~.~~ncbi~~.~~nlm~~.~~nih~~.~~gov/pmc/articles/PMC2563151/?tool~~=~~pubmed~~ }}</ref>		#'''''Must''''' be <=1.5 cm as per 2016 WHO classification.<ref name=pmid26935559>{{Cite journal \| last1 = Moch \| first1 = H. \| last2 = Cubilla \| first2 = AL. \| last3 = Humphrey \| first3 = PA. \| last4 = Reuter \| first4 = VE. \| last5 = Ulbright \| first5 = TM. \| title = The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs-Part A: Renal, Penile, and Testicular Tumours. \| journal = Eur Urol \| volume = \| issue = \| pages = \| month = Feb \| year = 2016 \| doi = 10.1016/j.eururo.2016.02.029 \| PMID = 26935559 }}</ref>
	#*[[Diagnostic size cutoff]] - larger lesions are ''papillary renal cell carcinoma''.		#*[[Diagnostic size cutoff]] - larger lesions are ''papillary renal cell carcinoma''.

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	*[[Metanephric adenoma]].		*[[Metanephric adenoma]].

			Note:
			*The size cut-off used to be <=0.5 cm.<ref name=pmid26935559/><ref name=Ref_GUP288>{{Ref GUP\|288}}</ref><ref name=pmid18846240>{{Cite journal \| last1 = Algaba \| first1 = F. \| title = Renal adenomas: pathological differential diagnosis with malignant tumors. \| journal = Adv Urol \| volume = \| issue = \| pages = 974848 \| month = \| year = 2008 \| doi = 10.1155/2008/974848 \| PMID = 18846240 \| PMC = 2563151 \| URL = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2563151/?tool=pubmed }}</ref>
	===Images===		===Images===
	<gallery>		<gallery>

Michael at 02:18, 10 October 2014

2014-10-10T02:18:58Z

← Older revision		Revision as of 02:18, 10 October 2014
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	\| Caption = Papillary adenoma. [[H&E stain]].		\| Caption = Papillary adenoma. [[H&E stain]].
	\| Synonyms = papillary adenoma, renal papillary adenoma		\| Synonyms = papillary adenoma, renal papillary adenoma
	\| Micro = papillae typically with foam cells, +/-psammoma bodies, nuclei usu. low grade		\| Micro = papillae typically with foam cells, +/-psammoma bodies, nuclei usu. low grade, '''must''' be <=0.5 cm
	\| Subtypes =		\| Subtypes =
	\| LMDDx = [[papillary renal cell carcinoma]], [[metanephric adenoma]]		\| LMDDx = [[papillary renal cell carcinoma]], [[metanephric adenoma]]
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	\| Molecular =		\| Molecular =
	\| IF =		\| IF =
	\| Gross = ~~'''must''' be <=0.5 cm,~~ typically subcapsular location		\| Gross = typically subcapsular location
	\| Grossing =		\| Grossing =
	\| Site = [[kidney]] - see ''[[kidney tumours]]''		\| Site = [[kidney]] - see ''[[kidney tumours]]''

Michael: /* Gross */

2014-10-10T02:18:12Z

Gross

← Older revision		Revision as of 02:18, 10 October 2014
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	*Cortical kidney lesion.		*Cortical kidney lesion.
	**Usually subcapsular.		**Usually subcapsular.
	*'''Must''' be <=0.5 cm.

	==Microscopic==		==Microscopic==