Perineural invasion - Revision history

Michael at 01:09, 21 April 2015

2015-04-21T01:09:41Z

← Older revision		Revision as of 01:09, 21 April 2015
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	[[Image:Prostatic adenocarcinoma with perineural invasion.JPG\|thumb\|right\|~~250px~~\|Perineural invasion in prostate carcinoma. [[H&E stain]].]]		[[Image:Prostatic adenocarcinoma with perineural invasion.JPG\|thumb\|right\|300px\|Perineural invasion in prostate carcinoma. [[H&E stain]].]]
	'''Perineural invasion''', also known as '''perineural tumour''', is the presence of a tumour within the nerve sheath. It is abbreviated as '''PNI'''.		'''Perineural invasion''', also known as '''perineural tumour''', is the presence of a tumour within the nerve sheath. It is abbreviated as '''PNI'''.

Michael at 05:00, 19 October 2014

2014-10-19T05:00:39Z

← Older revision		Revision as of 05:00, 19 October 2014
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			[[Image:Prostatic adenocarcinoma with perineural invasion.JPG\|thumb\|right\|250px\|Perineural invasion in prostate carcinoma. [[H&E stain]].]]
	'''Perineural invasion''', also known as '''perineural tumour''', is the presence of a tumour within the nerve sheath. It is abbreviated as '''PNI'''.		'''Perineural invasion''', also known as '''perineural tumour''', is the presence of a tumour within the nerve sheath. It is abbreviated as '''PNI'''.

Michael: /* Microscopic */

2013-12-18T03:32:32Z

Microscopic

← Older revision		Revision as of 03:32, 18 December 2013
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	DDx:		DDx:
	*Benign perineural glands (known as ''benign perineural involvement'').<ref name=pmid16096404>{{Cite journal \| last1 = Ali \| first1 = TZ. \| last2 = Epstein \| first2 = JI. \| title = Perineural involvement by benign prostatic glands on needle biopsy. \| journal = Am J Surg Pathol \| volume = 29 \| issue = 9 \| pages = 1159-63 \| month = Sep \| year = 2005 \| doi = \| PMID = 16096404 }}</ref>		*Benign perineural glands (known as ''benign perineural involvement'').<ref name=pmid16096404>{{Cite journal \| last1 = Ali \| first1 = TZ. \| last2 = Epstein \| first2 = JI. \| title = Perineural involvement by benign prostatic glands on needle biopsy. \| journal = Am J Surg Pathol \| volume = 29 \| issue = 9 \| pages = 1159-63 \| month = Sep \| year = 2005 \| doi = \| PMID = 16096404 }}</ref>
			**Should ''not'' completely wrap around the gland.
	===Images===		===Images===
	<gallery>		<gallery>

Michael at 20:39, 17 December 2013

2013-12-17T20:39:16Z

← Older revision		Revision as of 20:39, 17 December 2013
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	Features:		Features:
	*Tumour within the nerve sheath.		*Tumour within the nerve sheath.

			DDx:
			*Benign perineural glands (known as ''benign perineural involvement'').<ref name=pmid16096404>{{Cite journal \| last1 = Ali \| first1 = TZ. \| last2 = Epstein \| first2 = JI. \| title = Perineural involvement by benign prostatic glands on needle biopsy. \| journal = Am J Surg Pathol \| volume = 29 \| issue = 9 \| pages = 1159-63 \| month = Sep \| year = 2005 \| doi = \| PMID = 16096404 }}</ref>

	===Images===		===Images===

Michael: /* Microscopic */ +images

2013-05-31T23:52:41Z

Microscopic: +images

← Older revision		Revision as of 23:52, 31 May 2013
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	*Tumour within the nerve sheath.		*Tumour within the nerve sheath.

	Images:		===Images===
	*[http://commons.wikimedia.org/wiki/File:Prostatic_adenocarcinoma_with_perineural_invasion.JPG Prostate adenocarcinoma with PNI - obvious (WC)].		<gallery>
	*[http://commons.wikimedia.org/wiki/File:Perineural_invasion_prostate_high_mag.jpg Prostate adenocarcinoma with PNI (WC)].		Image:Prostatic_adenocarcinoma_with_perineural_invasion.JPG \| Prostate adenocarcinoma with PNI - obvious (WC/Nephron)
			Image:Perineural_invasion_prostate_high_mag.jpg \| Prostate adenocarcinoma with PNI (WC/Nephron)
			</gallery>

	==See also==		==See also==

Michael: nl update 23

2012-08-10T01:43:31Z

nl update 23

New page

'''Perineural invasion''', also known as '''perineural tumour''', is the presence of a tumour within the nerve sheath. It is abbreviated as '''PNI'''.

Generally, it is an indicator of a poor prognosis.

==Specific tumours==
{| class="wikitable sortable"
!Tumour
!Prognosis
!Comment
|-
| Colorectal carcinoma
| independent predictor<ref name=pmid19738119>{{Cite journal | last1 = Liebig | first1 = C. | last2 = Ayala | first2 = G. | last3 = Wilks | first3 = J. | last4 = Verstovsek | first4 = G. | last5 = Liu | first5 = H. | last6 = Agarwal | first6 = N. | last7 = Berger | first7 = DH. | last8 = Albo | first8 = D. | title = Perineural invasion is an independent predictor of outcome in colorectal cancer. | journal = J Clin Oncol | volume = 27 | issue = 31 | pages = 5131-7 | month = Nov | year = 2009 | doi = 10.1200/JCO.2009.22.4949 | PMID = 19738119 }}</ref>
|
|- 
|}

==Microscopic==
Features:
*Tumour within the nerve sheath.

Images:
*[http://commons.wikimedia.org/wiki/File:Prostatic_adenocarcinoma_with_perineural_invasion.JPG Prostate adenocarcinoma with PNI - obvious (WC)].
*[http://commons.wikimedia.org/wiki/File:Perineural_invasion_prostate_high_mag.jpg Prostate adenocarcinoma with PNI (WC)].

==See also==
*[[Lymphovascular invasion]].

==References==
{{Reflist|1}}

[[Category:Basics]]