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Pituicytoma - Revision history
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Jensflorian: created
2017-04-19T09:24:11Z
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<p><b>New page</b></p><div>'''Pituicytoma''' is a [[neuropathology tumour]] in the [neurohypophysis.<br />
<br />
==General==<br />
Features:<br />
*Low-grade glial neoplasm originating in the neurohypophysis.<br />
<br />
Grading:<br />
*WHO grade I.<br />
*ICD-O: 9432/1.<br />
<br />
==Gross==<br />
*Adherent to other sellar structures.<br />
*Solid.<br />
*Well-circumscribed.<br />
<br />
==Microscopic==<br />
*Solid compact growth pattern.<br />
*Bipolar spindle cells with distinctive cell borders.<br />
*Rare mitoses.<br />
*Few intercellular reticulin.<br />
<br />
==IHC==<br />
*GFAP: variable.<br />
*S-100+ve.<br />
*EMA: patchy.<br />
*TTF1+ve.<br />
*Synaptophysin -ve.<br />
*Mib-1: low.<br />
<br />
DDx:<br />
*Pilocytic astrocytoma (Rosenthal fibers, eosinophilic granular bodies)<br />
*Normal neurohypophysis<br />
*Spindle cell oncocytoma<br />
<br />
===Images===<br />
<gallery><br />
File:Pituicytoma.jpg| Pituicytoma. (WC)<br />
File:Pituicytoma TTF1.jpg | TTF1 in a pituicytoma. (WC)<br />
</gallery><br />
<br />
Note:<br />
It is thoought that Spindle cell oncocytomas and granular cell tumors of the pituitary are variants of pituicytoma.<ref>{{Cite journal | last1 = Mete | first1 = O. | last2 = Lopes | first2 = MB. | last3 = Asa | first3 = SL. | title = Spindle cell oncocytomas and granular cell tumors of the pituitary are variants of pituicytoma. | journal = Am J Surg Pathol | volume = 37 | issue = 11 | pages = 1694-9 | month = Nov | year = 2013 | doi = 10.1097/PAS.0b013e31829723e7 | PMID = 23887161 }}</ref><br />
<br />
<br />
==See also==<br />
*[[Neuropathology tumours]].<br />
*[[Pituitary gland]].<br />
<br />
==References==<br />
{{Reflist|2}}<br />
<br />
[[Category:Diagnosis]]<br />
[[Category:Neuropathology tumours]]</div>
Jensflorian