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Polar Spongioblastoma - Revision history
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2015-10-15T09:18:12Z
<p>Old entity....</p>
<p><b>New page</b></p><div>'''Polar Spongioblastoma''' is a depreceated tumour entity. It was categorized in the WHO 1993 and WHO 1997 classfication as neuroepithelial tumour of uncertain origin without assigning a WHO grade (ICD-O code 9423/3). The tumour was removed as distinct entity in the WHO 2000 classification.<br />
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In the first description in 1948 the tumour was characterized by bipolar tumor cells with palisading nuclei. There was a long standing controversy, whether the tumour was a morphologically a distinct entity or merely a occasionally observed growth pattern in conventional giomas, especially ependymomas or oligodendrogliomas. <ref>{{Cite journal | last1 = Schiffer | first1 = D. | last2 = Cravioto | first2 = H. | last3 = Giordana | first3 = MT. | last4 = Migheli | first4 = A. | last5 = Pezzulo | first5 = T. | last6 = Vigliani | first6 = MC. | title = Is polar spongioblastoma a tumor entity? | journal = J Neurosurg | volume = 78 | issue = 4 | pages = 587-91 | month = Apr | year = 1993 | doi = 10.3171/jns.1993.78.4.0587 | PMID = 8450332 }}</ref><ref>{{Cite journal | last1 = Jansen | first1 = GH. | last2 = Troost | first2 = D. | last3 = Dingemans | first3 = KP. | title = Polar spongioblastoma: an immunohistochemical and electron microscopical study. | journal = Acta Neuropathol | volume = 81 | issue = 2 | pages = 228-32 | month = | year = 1990 | doi = | PMID = 1707207 }}</ref><ref>{{Cite journal | last1 = Langford | first1 = LA. | last2 = Camel | first2 = MH. | title = Palisading pattern in cerebral neuroblastoma mimicking the primitive polar spongioblastoma. An ultrastructural study. | journal = Acta Neuropathol | volume = 73 | issue = 2 | pages = 153-9 | month = | year = 1987 | doi = | PMID = 3604582 }}</ref><br />
The growth pattern and molecular profile is discussed in single case reports.<ref>{{Cite journal | last1 = Fukushima | first1 = S. | last2 = Narita | first2 = Y. | last3 = Shinomiya | first3 = A. | last4 = Ohno | first4 = M. | last5 = Miyakita | first5 = Y. | last6 = Okita | first6 = Y. | last7 = Hanakawa | first7 = K. | last8 = Ide | first8 = T. | last9 = Kayama | first9 = T. | title = A case of unclassified high-grade glioma with polar spongioblastoma pattern. | journal = Neuropathology | volume = 32 | issue = 6 | pages = 604-10 | month = Dec | year = 2012 | doi = 10.1111/j.1440-1789.2012.01303.x | PMID = 22393945 }}</ref><ref>{{Cite journal | last1 = Nagaishi | first1 = M. | last2 = Tanaka | first2 = Y. | last3 = Iwatate | first3 = K. | last4 = Yokoo | first4 = H. | last5 = Ueki | first5 = K. | last6 = Hyodo | first6 = A. | last7 = Nakazato | first7 = Y. | title = Polar spongioblastoma: A high-grade glioma that does not contain the IDH1 mutation or 1p/19q LOH. | journal = Neuropathology | volume = 30 | issue = 5 | pages = 547-52 | month = Oct | year = 2010 | doi = 10.1111/j.1440-1789.2009.01087.x | PMID = 20102524 }}</ref><br />
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==Image==<br />
Exemplary image in [ pubcan.org [http://www.google.de/imgres?imgurl=http%3A%2F%2Fwww.pubcan.org%2Fimages%2Fthumb%2F0105.jpg&imgrefurl=http%3A%2F%2Fwww.pubcan.org%2Fcancer%2F5062%2Fpolar-spongioblastoma%2Fhistopathology&h=540&w=800&tbnid=uCdKTSmM0b4LWM%3A&]]<br />
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==See also==<br />
*[[Neuropathology tumours]].<br />
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==References==<br />
{{Reflist|2}}<br />
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[[Category:Neuropathology tumours]]</div>
Jensflorian