Proton pump inhibitor effect - Revision history

Michael: /* Microscopic */ tweak

2020-03-02T18:36:47Z

Microscopic: tweak

← Older revision		Revision as of 18:36, 2 March 2020
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	==Microscopic==		==Microscopic==
	Features:<ref>{{Cite journal \| last1 = Driman \| first1 = DK. \| last2 = Wright \| first2 = C. \| last3 = Tougas \| first3 = G. \| last4 = Riddell \| first4 = RH. \| title = Omeprazole produces parietal cell hypertrophy and hyperplasia in humans. \| journal = Dig Dis Sci \| volume = 41 \| issue = 10 \| pages = 2039-47 \| month = Oct \| year = 1996 \| doi = \| PMID = 8888719 }}</ref> <ref>{{Pathologyoutlines\| topic/stomachPPI}}</ref>		Features:<ref name=pmid8888719>{{Cite journal \| last1 = Driman \| first1 = DK. \| last2 = Wright \| first2 = C. \| last3 = Tougas \| first3 = G. \| last4 = Riddell \| first4 = RH. \| title = Omeprazole produces parietal cell hypertrophy and hyperplasia in humans. \| journal = Dig Dis Sci \| volume = 41 \| issue = 10 \| pages = 2039-47 \| month = Oct \| year = 1996 \| doi = \| PMID = 8888719 }}</ref><ref>{{Pathologyoutlines\| topic/stomachPPI}}</ref>
	*Parietal cell enlargement - '''key feature'''.		*Parietal cell enlargement - '''key feature'''.
	**Parietal cells typically bulge into the lumen.		**Parietal cells typically bulge into the lumen.
	*G cell and enterochromaffin cell-like hyperplasia		*G cell and enterochromaffin cell-like hyperplasia.
	**Compensatory change due to increased pH in gastric lumen.		**Compensatory change due to increased pH in gastric lumen.
	*Multiple fundic gland polyps (with PPI use over several months)		*Multiple fundic gland polyps (with PPI use over several months).
	**Polyps may regress after PPI is stopped		**Polyps may regress after PPI is stopped.

	===Images===		===Images===

Sarah A: /* Microscopic */

2020-03-02T15:18:42Z

Microscopic

← Older revision		Revision as of 15:18, 2 March 2020
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	==Microscopic==		==Microscopic==
	Features:<ref>{{Cite journal \| last1 = Driman \| first1 = DK. \| last2 = Wright \| first2 = C. \| last3 = Tougas \| first3 = G. \| last4 = Riddell \| first4 = RH. \| title = Omeprazole produces parietal cell hypertrophy and hyperplasia in humans. \| journal = Dig Dis Sci \| volume = 41 \| issue = 10 \| pages = 2039-47 \| month = Oct \| year = 1996 \| doi = \| PMID = 8888719 }}</ref>		Features:<ref>{{Cite journal \| last1 = Driman \| first1 = DK. \| last2 = Wright \| first2 = C. \| last3 = Tougas \| first3 = G. \| last4 = Riddell \| first4 = RH. \| title = Omeprazole produces parietal cell hypertrophy and hyperplasia in humans. \| journal = Dig Dis Sci \| volume = 41 \| issue = 10 \| pages = 2039-47 \| month = Oct \| year = 1996 \| doi = \| PMID = 8888719 }}</ref> <ref>{{Pathologyoutlines\| topic/stomachPPI}}</ref>
	*Parietal cell enlargement - '''key feature'''.		*Parietal cell enlargement - '''key feature'''.
	**Parietal cells typically bulge into the lumen.		**Parietal cells typically bulge into the lumen.
			*G cell and enterochromaffin cell-like hyperplasia
			**Compensatory change due to increased pH in gastric lumen.
			*Multiple fundic gland polyps (with PPI use over several months)
			**Polyps may regress after PPI is stopped

	===Images===		===Images===

Michael: /* See also */

2015-05-16T10:18:04Z

Michael: /* General */

2014-02-03T02:03:03Z

General

← Older revision		Revision as of 02:03, 3 February 2014
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	**Used to treat [[gastroesophageal reflux disease]].		**Used to treat [[gastroesophageal reflux disease]].

	Some proton pump inhibitors:		===Some proton pump inhibitors===
	*Omeprazole (LOSEC).		{\| class="wikitable sortable"
	*Dexlansoprazole (DEXILANT).		! Generic name
	*Lansoprazole (PREVACID).		! Brand name(s)
	*Esomeprazole (NEXIUM).		\|-
	*Pantoprazole (PANTOLOC).		\|Omeprazole
	*Rabeprazole (PARIET).		\|LOSEC
			\|-
			\|Dexlansoprazole
			\|DEXILANT
			\|-
			\|Lansoprazole
			\|PREVACID
			\|-
			\|Esomeprazole
			\|NEXIUM
			\|-
			\|Pantoprazole
			\|PANTOLOC
			\|-
			\|Rabeprazole
			\|PARIET
			\|}

	==Microscopic==		==Microscopic==

Michael at 21:13, 20 January 2014

2014-01-20T21:13:31Z

← Older revision		Revision as of 21:13, 20 January 2014
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	*Due to intake of a proton pump inhibitor (PPI).		*Due to intake of a proton pump inhibitor (PPI).
	**Used to treat [[gastroesophageal reflux disease]].		**Used to treat [[gastroesophageal reflux disease]].

			Some proton pump inhibitors:
			*Omeprazole (LOSEC).
			*Dexlansoprazole (DEXILANT).
			*Lansoprazole (PREVACID).
			*Esomeprazole (NEXIUM).
			*Pantoprazole (PANTOLOC).
			*Rabeprazole (PARIET).

	==Microscopic==		==Microscopic==

Michael at 00:11, 18 January 2014

2014-01-18T00:11:17Z

← Older revision		Revision as of 00:11, 18 January 2014
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	[[Image:Stomach with ~~PPI effect~~ -- very high mag.jpg\|thumb\|right\|250px\|Stomach with PPI effect. [[H&E stain]].]]		[[Image:Stomach with prominent parietal cells -- very high mag.jpg\|thumb\|right\|250px\|Stomach with PPI effect. [[H&E stain]].]]
	'''Proton pump inhibitor effect''', abbreviated '''PPI effect''', is a change seen in the parietal cells of the [[stomach]] due to a drug in the proton pump inhibitor class.		'''Proton pump inhibitor effect''', abbreviated '''PPI effect''', is a change seen in the parietal cells of the [[stomach]] due to a drug in the proton pump inhibitor class.

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	===Images===		===Images===
	<gallery>		<gallery>
	Image: Stomach with ~~PPI effect~~ -- intermed mag.jpg \| PPI effect - intermed. mag. ~~(WC)~~		Image: Stomach with prominent parietal cells -- intermed mag.jpg \| PPI effect - intermed. mag.
	Image: Stomach with ~~PPI effect~~ -- high mag.jpg \| PPI effect - high mag. ~~(WC)~~		Image: Stomach with prominent parietal cells -- high mag.jpg \| PPI effect - high mag.
	Image: Stomach with ~~PPI effect~~ -- very high mag.jpg \| PPI effect - very high mag. ~~(WC)~~		Image: Stomach with prominent parietal cells -- very high mag.jpg \| PPI effect - very high mag.
	</gallery>		</gallery>
	www:		www:

Michael at 04:43, 12 January 2014

2014-01-12T04:43:24Z

← Older revision		Revision as of 04:43, 12 January 2014
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	[[Image:Stomach with PPI effect -- very high mag.jpg\|thumb\|right\|Stomach with PPI effect. [[H&E stain]].]]		[[Image:Stomach with PPI effect -- very high mag.jpg\|thumb\|right\|250px\|Stomach with PPI effect. [[H&E stain]].]]
	'''Proton pump inhibitor effect''', abbreviated '''PPI effect''', is a change seen in the parietal cells of the [[stomach]] due to a drug in the proton pump inhibitor class.		'''Proton pump inhibitor effect''', abbreviated '''PPI effect''', is a change seen in the parietal cells of the [[stomach]] due to a drug in the proton pump inhibitor class.

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	Features:<ref>{{Cite journal \| last1 = Driman \| first1 = DK. \| last2 = Wright \| first2 = C. \| last3 = Tougas \| first3 = G. \| last4 = Riddell \| first4 = RH. \| title = Omeprazole produces parietal cell hypertrophy and hyperplasia in humans. \| journal = Dig Dis Sci \| volume = 41 \| issue = 10 \| pages = 2039-47 \| month = Oct \| year = 1996 \| doi = \| PMID = 8888719 }}</ref>		Features:<ref>{{Cite journal \| last1 = Driman \| first1 = DK. \| last2 = Wright \| first2 = C. \| last3 = Tougas \| first3 = G. \| last4 = Riddell \| first4 = RH. \| title = Omeprazole produces parietal cell hypertrophy and hyperplasia in humans. \| journal = Dig Dis Sci \| volume = 41 \| issue = 10 \| pages = 2039-47 \| month = Oct \| year = 1996 \| doi = \| PMID = 8888719 }}</ref>
	*Parietal cell enlargement - '''key feature'''.		*Parietal cell enlargement - '''key feature'''.
			**Parietal cells typically bulge into the lumen.

	===Images===		===Images===

Michael: +images

2014-01-12T04:41:40Z

+images

← Older revision		Revision as of 04:41, 12 January 2014
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			[[Image:Stomach with PPI effect -- very high mag.jpg\|thumb\|right\|Stomach with PPI effect. [[H&E stain]].]]
	'''Proton pump inhibitor effect''', abbreviated '''PPI effect''', is a change seen in the parietal cells of the [[stomach]] due to a drug in the proton pump inhibitor class.		'''Proton pump inhibitor effect''', abbreviated '''PPI effect''', is a change seen in the parietal cells of the [[stomach]] due to a drug in the proton pump inhibitor class.

			Formally, it is '''stomach with proton pump inhibitor effect'''.

	==General==		==General==
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	===Images===		===Images===
			<gallery>
			Image: Stomach with PPI effect -- intermed mag.jpg \| PPI effect - intermed. mag. (WC)
			Image: Stomach with PPI effect -- high mag.jpg \| PPI effect - high mag. (WC)
			Image: Stomach with PPI effect -- very high mag.jpg \| PPI effect - very high mag. (WC)
			</gallery>
	www:		www:
	*[http://www.nature.com/nrgastro/journal/v4/n8/images/ncpgasthep0896-f3.jpg PPI effect (nature.com)].		*[http://www.nature.com/nrgastro/journal/v4/n8/images/ncpgasthep0896-f3.jpg PPI effect (nature.com)].

Michael at 17:45, 10 January 2014

2014-01-10T17:45:45Z

← Older revision		Revision as of 17:45, 10 January 2014
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	Features:<ref>{{Cite journal \| last1 = Driman \| first1 = DK. \| last2 = Wright \| first2 = C. \| last3 = Tougas \| first3 = G. \| last4 = Riddell \| first4 = RH. \| title = Omeprazole produces parietal cell hypertrophy and hyperplasia in humans. \| journal = Dig Dis Sci \| volume = 41 \| issue = 10 \| pages = 2039-47 \| month = Oct \| year = 1996 \| doi = \| PMID = 8888719 }}</ref>		Features:<ref>{{Cite journal \| last1 = Driman \| first1 = DK. \| last2 = Wright \| first2 = C. \| last3 = Tougas \| first3 = G. \| last4 = Riddell \| first4 = RH. \| title = Omeprazole produces parietal cell hypertrophy and hyperplasia in humans. \| journal = Dig Dis Sci \| volume = 41 \| issue = 10 \| pages = 2039-47 \| month = Oct \| year = 1996 \| doi = \| PMID = 8888719 }}</ref>
	*Parietal cell enlargement - '''key feature'''.		*Parietal cell enlargement - '''key feature'''.

			===Images===
			www:
			*[http://www.nature.com/nrgastro/journal/v4/n8/images/ncpgasthep0896-f3.jpg PPI effect (nature.com)].

	==Sign out==		==Sign out==

Michael: create

2014-01-10T17:45:18Z

create

New page

'''Proton pump inhibitor effect''', abbreviated '''PPI effect''', is a change seen in the parietal cells of the [[stomach]] due to a drug in the proton pump inhibitor class.

==General==
*Due to intake of a proton pump inhibitor (PPI).
**Used to treat [[gastroesophageal reflux disease]].

==Microscopic==
Features:<ref>{{Cite journal | last1 = Driman | first1 = DK. | last2 = Wright | first2 = C. | last3 = Tougas | first3 = G. | last4 = Riddell | first4 = RH. | title = Omeprazole produces parietal cell hypertrophy and hyperplasia in humans. | journal = Dig Dis Sci | volume = 41 | issue = 10 | pages = 2039-47 | month = Oct | year = 1996 | doi = | PMID = 8888719 }}</ref>
*Parietal cell enlargement - '''key feature'''.

==Sign out==
*Usually not reported.

==See also==
*[[Stomach]].

==References==
{{Reflist|1}}

[[Category:Stomach]]

← Older revision		Revision as of 10:18, 16 May 2015
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	==See also==		==See also==
	*[[Stomach]].		*[[Stomach]].
			*[[Glycogenic acanthosis of the esophagus]].

	==References==		==References==