Pulmonary carcinoid tumourlet - Revision history

Michael at 03:30, 22 March 2018

2018-03-22T03:30:29Z

← Older revision		Revision as of 03:30, 22 March 2018
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	\| Site = [[lung]] - see ''[[lung tumours]]''		\| Site = [[lung]] - see ''[[lung tumours]]''
	\| Assdx =		\| Assdx =
	\| Syndromes = [[~~DIPNECH~~]]		\| Syndromes = [[Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia]]
	\| Clinicalhx = often an incidental finding		\| Clinicalhx = often an incidental finding
	\| Signs =		\| Signs =

Michael: +syndrome

2018-03-22T03:29:10Z

+syndrome

← Older revision		Revision as of 03:29, 22 March 2018
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	\| Site = [[lung]] - see ''[[lung tumours]]''		\| Site = [[lung]] - see ''[[lung tumours]]''
	\| Assdx =		\| Assdx =
	\| Syndromes =		\| Syndromes = [[DIPNECH]]
	\| Clinicalhx = often an incidental finding		\| Clinicalhx = often an incidental finding
	\| Signs =		\| Signs =

Michael: /* Microscopic */

2016-04-21T12:39:09Z

Microscopic

← Older revision		Revision as of 12:39, 21 April 2016
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	*Neuroendocrine cells - usually in nests (classic pattern).		*Neuroendocrine cells - usually in nests (classic pattern).
	**Salt and pepper chromatin - '''key feature'''.		**Salt and pepper chromatin - '''key feature'''.
			*Nuclei round or ellipsoid.
	*Size criterion: <5 mm.<ref name=pct_ucsf>URL: [http://pathhsw5m54.ucsf.edu/case7/image75.html http://pathhsw5m54.ucsf.edu/case7/image75.html]. Accessed on: 23 January 2012.</ref><ref name=pmid23205296>{{Cite journal \| last1 = He \| first1 = P. \| last2 = Gu \| first2 = X. \| last3 = Wu \| first3 = Q. \| last4 = Lin \| first4 = Y. \| last5 = Gu \| first5 = Y. \| last6 = He \| first6 = J. \| title = Pulmonary carcinoid tumorlet without underlying lung disease: analysis of its relationship to fibrosis. \| journal = J Thorac Dis \| volume = 4 \| issue = 6 \| pages = 655-8 \| month = Dec \| year = 2012 \| doi = 10.3978/j.issn.2072-1439.2012.06.11 \| PMID = 23205296 }}</ref>		*Size criterion: <5 mm.<ref name=pct_ucsf>URL: [http://pathhsw5m54.ucsf.edu/case7/image75.html http://pathhsw5m54.ucsf.edu/case7/image75.html]. Accessed on: 23 January 2012.</ref><ref name=pmid23205296>{{Cite journal \| last1 = He \| first1 = P. \| last2 = Gu \| first2 = X. \| last3 = Wu \| first3 = Q. \| last4 = Lin \| first4 = Y. \| last5 = Gu \| first5 = Y. \| last6 = He \| first6 = J. \| title = Pulmonary carcinoid tumorlet without underlying lung disease: analysis of its relationship to fibrosis. \| journal = J Thorac Dis \| volume = 4 \| issue = 6 \| pages = 655-8 \| month = Dec \| year = 2012 \| doi = 10.3978/j.issn.2072-1439.2012.06.11 \| PMID = 23205296 }}</ref>
	*Must be through the bronchial basement membrane.<ref name=pmid20729444>{{Cite journal \| last1 = Koo \| first1 = CW. \| last2 = Baliff \| first2 = JP. \| last3 = Torigian \| first3 = DA. \| last4 = Litzky \| first4 = LA. \| last5 = Gefter \| first5 = WB. \| last6 = Akers \| first6 = SR. \| title = Spectrum of pulmonary neuroendocrine cell proliferation: diffuse idiopathic pulmonary neuroendocrine cell hyperplasia, tumorlet, and carcinoids. \| journal = AJR Am J Roentgenol \| volume = 195 \| issue = 3 \| pages = 661-8 \| month = Sep \| year = 2010 \| doi = 10.2214/AJR.09.3811 \| PMID = 20729444 }}</ref>		*Must be through the bronchial basement membrane.<ref name=pmid20729444>{{Cite journal \| last1 = Koo \| first1 = CW. \| last2 = Baliff \| first2 = JP. \| last3 = Torigian \| first3 = DA. \| last4 = Litzky \| first4 = LA. \| last5 = Gefter \| first5 = WB. \| last6 = Akers \| first6 = SR. \| title = Spectrum of pulmonary neuroendocrine cell proliferation: diffuse idiopathic pulmonary neuroendocrine cell hyperplasia, tumorlet, and carcinoids. \| journal = AJR Am J Roentgenol \| volume = 195 \| issue = 3 \| pages = 661-8 \| month = Sep \| year = 2010 \| doi = 10.2214/AJR.09.3811 \| PMID = 20729444 }}</ref>

Michael at 18:45, 11 November 2015

2015-11-11T18:45:25Z

← Older revision		Revision as of 18:45, 11 November 2015
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	\| Caption = Lung carcinoid tumourlet. [[H&E stain]].		\| Caption = Lung carcinoid tumourlet. [[H&E stain]].
	\| Synonyms = carcinoid tumourlet		\| Synonyms = carcinoid tumourlet
	\| Micro = cells with salt and pepper chromatin, usually nested architecture, no necrosis, minimal mitotic activity (see below)		\| Micro = cells with salt and pepper chromatin, usually nested architecture, no necrosis, minimal mitotic activity (see below), must be through the bronchial basement membrane
	\| Subtypes =		\| Subtypes =
	\| LMDDx = [[pulmonary neuroendocrine cell hyperplasia]], [[typical carcinoid lung tumour]], [[atypical lung carcinoid tumour]], [[pulmonary meningothelial-like nodule]]		\| LMDDx = [[pulmonary neuroendocrine cell hyperplasia]], [[typical carcinoid lung tumour]], [[atypical lung carcinoid tumour]], [[pulmonary meningothelial-like nodule]]

Michael: /* Microscopic */

2015-11-06T02:49:06Z

Microscopic

← Older revision		Revision as of 02:49, 6 November 2015
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	*[[Pulmonary neuroendocrine cell hyperplasia]] - proliferation confined by bronchial basement membrane.<ref name=pmid20729444>{{Cite journal \| last1 = Koo \| first1 = CW. \| last2 = Baliff \| first2 = JP. \| last3 = Torigian \| first3 = DA. \| last4 = Litzky \| first4 = LA. \| last5 = Gefter \| first5 = WB. \| last6 = Akers \| first6 = SR. \| title = Spectrum of pulmonary neuroendocrine cell proliferation: diffuse idiopathic pulmonary neuroendocrine cell hyperplasia, tumorlet, and carcinoids. \| journal = AJR Am J Roentgenol \| volume = 195 \| issue = 3 \| pages = 661-8 \| month = Sep \| year = 2010 \| doi = 10.2214/AJR.09.3811 \| PMID = 20729444 }}</ref>		*[[Pulmonary neuroendocrine cell hyperplasia]] - proliferation confined by bronchial basement membrane.<ref name=pmid20729444>{{Cite journal \| last1 = Koo \| first1 = CW. \| last2 = Baliff \| first2 = JP. \| last3 = Torigian \| first3 = DA. \| last4 = Litzky \| first4 = LA. \| last5 = Gefter \| first5 = WB. \| last6 = Akers \| first6 = SR. \| title = Spectrum of pulmonary neuroendocrine cell proliferation: diffuse idiopathic pulmonary neuroendocrine cell hyperplasia, tumorlet, and carcinoids. \| journal = AJR Am J Roentgenol \| volume = 195 \| issue = 3 \| pages = 661-8 \| month = Sep \| year = 2010 \| doi = 10.2214/AJR.09.3811 \| PMID = 20729444 }}</ref>
	*[[Typical carcinoid lung tumour]] - must be >= 5 mm.		*[[Typical carcinoid lung tumour]] - must be >= 5 mm.
	*[[Pulmonary meningothelial-like nodule]].		*[[Pulmonary meningothelial-like nodule]] - whorled appearance, ''not'' associated with an airway.

	===Images===		===Images===

Michael at 01:39, 30 September 2015

2015-09-30T01:39:33Z

← Older revision		Revision as of 01:39, 30 September 2015
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	\| Micro = cells with salt and pepper chromatin, usually nested architecture, no necrosis, minimal mitotic activity (see below)		\| Micro = cells with salt and pepper chromatin, usually nested architecture, no necrosis, minimal mitotic activity (see below)
	\| Subtypes =		\| Subtypes =
	\| LMDDx = [[pulmonary neuroendocrine cell hyperplasia]], [[typical carcinoid lung tumour]], [[atypical lung carcinoid tumour]]		\| LMDDx = [[pulmonary neuroendocrine cell hyperplasia]], [[typical carcinoid lung tumour]], [[atypical lung carcinoid tumour]], [[pulmonary meningothelial-like nodule]]
	\| Stains =		\| Stains =
	\| IHC = Ki-67 ~2% (0-7%)		\| IHC = Ki-67 ~2% (0-7%)

Michael: /* Microscopic */

2015-09-30T01:39:13Z

Microscopic

← Older revision		Revision as of 01:39, 30 September 2015
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	*[[Pulmonary neuroendocrine cell hyperplasia]] - proliferation confined by bronchial basement membrane.<ref name=pmid20729444>{{Cite journal \| last1 = Koo \| first1 = CW. \| last2 = Baliff \| first2 = JP. \| last3 = Torigian \| first3 = DA. \| last4 = Litzky \| first4 = LA. \| last5 = Gefter \| first5 = WB. \| last6 = Akers \| first6 = SR. \| title = Spectrum of pulmonary neuroendocrine cell proliferation: diffuse idiopathic pulmonary neuroendocrine cell hyperplasia, tumorlet, and carcinoids. \| journal = AJR Am J Roentgenol \| volume = 195 \| issue = 3 \| pages = 661-8 \| month = Sep \| year = 2010 \| doi = 10.2214/AJR.09.3811 \| PMID = 20729444 }}</ref>		*[[Pulmonary neuroendocrine cell hyperplasia]] - proliferation confined by bronchial basement membrane.<ref name=pmid20729444>{{Cite journal \| last1 = Koo \| first1 = CW. \| last2 = Baliff \| first2 = JP. \| last3 = Torigian \| first3 = DA. \| last4 = Litzky \| first4 = LA. \| last5 = Gefter \| first5 = WB. \| last6 = Akers \| first6 = SR. \| title = Spectrum of pulmonary neuroendocrine cell proliferation: diffuse idiopathic pulmonary neuroendocrine cell hyperplasia, tumorlet, and carcinoids. \| journal = AJR Am J Roentgenol \| volume = 195 \| issue = 3 \| pages = 661-8 \| month = Sep \| year = 2010 \| doi = 10.2214/AJR.09.3811 \| PMID = 20729444 }}</ref>
	*[[Typical carcinoid lung tumour]] - must be >= 5 mm.		*[[Typical carcinoid lung tumour]] - must be >= 5 mm.
			*[[Pulmonary meningothelial-like nodule]].

	===Images===		===Images===

Michael at 01:18, 30 September 2015

2015-09-30T01:18:35Z

← Older revision		Revision as of 01:18, 30 September 2015
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	{{ Infobox diagnosis		{{ Infobox diagnosis
	\| Name = {{PAGENAME}}		\| Name = {{PAGENAME}}
	\| Image =		\| Image = Lung carcinoid tumourlet - low mag.jpg
	\| Width =		\| Width =
	\| Caption =		\| Caption = Lung carcinoid tumourlet. [[H&E stain]].
	\| Synonyms = carcinoid tumourlet		\| Synonyms = carcinoid tumourlet
	\| Micro = cells with salt and pepper chromatin, usually nested architecture, no necrosis, minimal mitotic activity (see below)		\| Micro = cells with salt and pepper chromatin, usually nested architecture, no necrosis, minimal mitotic activity (see below)
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	===Images===		===Images===
			<gallery>
			Image: Lung carcinoid tumourlet - very low mag.jpg \| CT - very low mag. (WC)
			Image: Lung carcinoid tumourlet - low mag.jpg \| CT - low mag. (WC)
			Image: Lung carcinoid tumourlet - intermed mag.jpg \| CT - intermed. mag. (WC)
			Image: Lung carcinoid tumourlet - high mag.jpg \| CT - high mag. (WC)
			Image: Lung carcinoid tumourlet - alt - high mag.jpg \| CT - high mag. (WC)
			Image: Lung carcinoid tumourlet - very high mag.jpg \| CT - very high mag. (WC)
			Image: Lung carcinoid tumourlet - alt - very high mag.jpg \| CT - very high mag. (WC)
			</gallery>
			www:
	*[http://pathhsw5m54.ucsf.edu/case7/image75.html Tumourlets - several images (ucsf.edu)].		*[http://pathhsw5m54.ucsf.edu/case7/image75.html Tumourlets - several images (ucsf.edu)].

Michael: /* Microscopic */

2015-09-25T19:13:48Z

Microscopic

← Older revision		Revision as of 19:13, 25 September 2015
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	==Microscopic==		==Microscopic==
	Features:		Features:
	*~~Nests of~~ cells - classic pattern.		*Neuroendocrine cells - usually in nests (classic pattern).
	**Salt and pepper chromatin - '''key feature'''.		**Salt and pepper chromatin - '''key feature'''.
	*Size criterion: <5 mm.<ref name=pct_ucsf>URL: [http://pathhsw5m54.ucsf.edu/case7/image75.html http://pathhsw5m54.ucsf.edu/case7/image75.html]. Accessed on: 23 January 2012.</ref><ref name=pmid23205296>{{Cite journal \| last1 = He \| first1 = P. \| last2 = Gu \| first2 = X. \| last3 = Wu \| first3 = Q. \| last4 = Lin \| first4 = Y. \| last5 = Gu \| first5 = Y. \| last6 = He \| first6 = J. \| title = Pulmonary carcinoid tumorlet without underlying lung disease: analysis of its relationship to fibrosis. \| journal = J Thorac Dis \| volume = 4 \| issue = 6 \| pages = 655-8 \| month = Dec \| year = 2012 \| doi = 10.3978/j.issn.2072-1439.2012.06.11 \| PMID = 23205296 }}</ref>		*Size criterion: <5 mm.<ref name=pct_ucsf>URL: [http://pathhsw5m54.ucsf.edu/case7/image75.html http://pathhsw5m54.ucsf.edu/case7/image75.html]. Accessed on: 23 January 2012.</ref><ref name=pmid23205296>{{Cite journal \| last1 = He \| first1 = P. \| last2 = Gu \| first2 = X. \| last3 = Wu \| first3 = Q. \| last4 = Lin \| first4 = Y. \| last5 = Gu \| first5 = Y. \| last6 = He \| first6 = J. \| title = Pulmonary carcinoid tumorlet without underlying lung disease: analysis of its relationship to fibrosis. \| journal = J Thorac Dis \| volume = 4 \| issue = 6 \| pages = 655-8 \| month = Dec \| year = 2012 \| doi = 10.3978/j.issn.2072-1439.2012.06.11 \| PMID = 23205296 }}</ref>
			*Must be through the bronchial basement membrane.<ref name=pmid20729444>{{Cite journal \| last1 = Koo \| first1 = CW. \| last2 = Baliff \| first2 = JP. \| last3 = Torigian \| first3 = DA. \| last4 = Litzky \| first4 = LA. \| last5 = Gefter \| first5 = WB. \| last6 = Akers \| first6 = SR. \| title = Spectrum of pulmonary neuroendocrine cell proliferation: diffuse idiopathic pulmonary neuroendocrine cell hyperplasia, tumorlet, and carcinoids. \| journal = AJR Am J Roentgenol \| volume = 195 \| issue = 3 \| pages = 661-8 \| month = Sep \| year = 2010 \| doi = 10.2214/AJR.09.3811 \| PMID = 20729444 }}</ref>

	DDx:		DDx:

Michael at 18:56, 25 September 2015

2015-09-25T18:56:49Z

← Older revision		Revision as of 18:56, 25 September 2015
Line 7:		Line 7:
	\| Micro = cells with salt and pepper chromatin, usually nested architecture, no necrosis, minimal mitotic activity (see below)		\| Micro = cells with salt and pepper chromatin, usually nested architecture, no necrosis, minimal mitotic activity (see below)
	\| Subtypes =		\| Subtypes =
	\| LMDDx = [[typical carcinoid lung tumour]], [[atypical lung carcinoid tumour]]		\| LMDDx = [[pulmonary neuroendocrine cell hyperplasia]], [[typical carcinoid lung tumour]], [[atypical lung carcinoid tumour]]
	\| Stains =		\| Stains =
	\| IHC = Ki-67 ~2% (0-7%)		\| IHC = Ki-67 ~2% (0-7%)