Radical prostatectomy - Revision history

Michael: /* Related protocols */

2025-01-17T21:05:11Z

Related protocols

← Older revision		Revision as of 21:05, 17 January 2025
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	*[[Prostate chips]].		*[[Prostate chips]].
	*[[Cystoprostatectomy]].		*[[Cystoprostatectomy]].
			*[[Simple prostatectomy]].

	==References==		==References==

Michael: /* Literature */

2016-02-01T17:28:22Z

Literature

← Older revision		Revision as of 17:28, 1 February 2016
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	*[[Lymph node]]s:<ref name=pmid20818343>{{Cite journal \| last1 = Berney \| first1 = DM. \| last2 = Wheeler \| first2 = TM. \| last3 = Grignon \| first3 = DJ. \| last4 = Epstein \| first4 = JI. \| last5 = Griffiths \| first5 = DF. \| last6 = Humphrey \| first6 = PA. \| last7 = van der Kwast \| first7 = T. \| last8 = Montironi \| first8 = R. \| last9 = Delahunt \| first9 = B. \| title = International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 4: seminal vesicles and lymph nodes. \| journal = Mod Pathol \| volume = 24 \| issue = 1 \| pages = 39-47 \| month = Jan \| year = 2011 \| doi = 10.1038/modpathol.2010.160 \| PMID = 20818343 }}</ref>		*[[Lymph node]]s:<ref name=pmid20818343>{{Cite journal \| last1 = Berney \| first1 = DM. \| last2 = Wheeler \| first2 = TM. \| last3 = Grignon \| first3 = DJ. \| last4 = Epstein \| first4 = JI. \| last5 = Griffiths \| first5 = DF. \| last6 = Humphrey \| first6 = PA. \| last7 = van der Kwast \| first7 = T. \| last8 = Montironi \| first8 = R. \| last9 = Delahunt \| first9 = B. \| title = International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 4: seminal vesicles and lymph nodes. \| journal = Mod Pathol \| volume = 24 \| issue = 1 \| pages = 39-47 \| month = Jan \| year = 2011 \| doi = 10.1038/modpathol.2010.160 \| PMID = 20818343 }}</ref>
	**All lymph nodes should be submitted.		**All lymph nodes should be submitted.
	***59% of the the ISUP ~~panel on the topic~~ believe submitting all of the the lymph nodes (without the surrounding fat) is sufficient.<ref name=pmid20818343/>		***59% of the the ISUP consensus conference participants believe submitting all of the the lymph nodes (without the surrounding fat) is sufficient.<ref name=pmid20818343/>
	***[[Lymph node metastasis\|Metastases]] are found in over 5% of tissue not grossly recognized as a lymph node (at frozen section);<ref name=pmid3773097>{{Cite journal \| last1 = Epstein \| first1 = JI. \| last2 = Oesterling \| first2 = JE. \| last3 = Eggleston \| first3 = JC. \| last4 = Walsh \| first4 = PC. \| title = Frozen section detection of lymph node metastases in prostatic carcinoma: accuracy in grossly uninvolved pelvic lymphadenectomy specimens. \| journal = J Urol \| volume = 136 \| issue = 6 \| pages = 1234-7 \| month = Dec \| year = 1986 \| doi = \| PMID = 3773097 }}</ref> thus, it is reasonable to submit all of the tissue.<ref>{{Cite journal \| last1 = Sung \| first1 = MT. \| last2 = davidson \| first2 = DD. \| last3 = Montironi \| first3 = R. \| last4 = Lopez-Beltran \| first4 = A. \| last5 = Cheng \| first4 = L. \| title = Radical prostatectomy specimen processing: a critical appraisal of sampling methods. \| journal = Current Diagnostic Pathology \| volume = 13 \| issue = \| pages = 490-498 \| month = \| year = 2007 \| doi = \| PMID = \| URL = http://www.journals.elsevierhealth.com/periodicals/ycdip/article/S0968-6053(07)00074-9/abstract }} </ref>		***[[Lymph node metastasis\|Metastases]] are found in over 5% of tissue not grossly recognized as a lymph node (at frozen section);<ref name=pmid3773097>{{Cite journal \| last1 = Epstein \| first1 = JI. \| last2 = Oesterling \| first2 = JE. \| last3 = Eggleston \| first3 = JC. \| last4 = Walsh \| first4 = PC. \| title = Frozen section detection of lymph node metastases in prostatic carcinoma: accuracy in grossly uninvolved pelvic lymphadenectomy specimens. \| journal = J Urol \| volume = 136 \| issue = 6 \| pages = 1234-7 \| month = Dec \| year = 1986 \| doi = \| PMID = 3773097 }}</ref> thus, it is reasonable to submit all of the tissue.<ref>{{Cite journal \| last1 = Sung \| first1 = MT. \| last2 = davidson \| first2 = DD. \| last3 = Montironi \| first3 = R. \| last4 = Lopez-Beltran \| first4 = A. \| last5 = Cheng \| first4 = L. \| title = Radical prostatectomy specimen processing: a critical appraisal of sampling methods. \| journal = Current Diagnostic Pathology \| volume = 13 \| issue = \| pages = 490-498 \| month = \| year = 2007 \| doi = \| PMID = \| URL = http://www.journals.elsevierhealth.com/periodicals/ycdip/article/S0968-6053(07)00074-9/abstract }} </ref>
	*Seminal vesicles (SV):<ref name=pmid20818343/>		*Seminal vesicles (SV):<ref name=pmid20818343/>

Michael: /* Literature */

2016-02-01T15:43:52Z

Literature

← Older revision		Revision as of 15:43, 1 February 2016
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	*[[Lymph node]]s:<ref name=pmid20818343>{{Cite journal \| last1 = Berney \| first1 = DM. \| last2 = Wheeler \| first2 = TM. \| last3 = Grignon \| first3 = DJ. \| last4 = Epstein \| first4 = JI. \| last5 = Griffiths \| first5 = DF. \| last6 = Humphrey \| first6 = PA. \| last7 = van der Kwast \| first7 = T. \| last8 = Montironi \| first8 = R. \| last9 = Delahunt \| first9 = B. \| title = International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 4: seminal vesicles and lymph nodes. \| journal = Mod Pathol \| volume = 24 \| issue = 1 \| pages = 39-47 \| month = Jan \| year = 2011 \| doi = 10.1038/modpathol.2010.160 \| PMID = 20818343 }}</ref>		*[[Lymph node]]s:<ref name=pmid20818343>{{Cite journal \| last1 = Berney \| first1 = DM. \| last2 = Wheeler \| first2 = TM. \| last3 = Grignon \| first3 = DJ. \| last4 = Epstein \| first4 = JI. \| last5 = Griffiths \| first5 = DF. \| last6 = Humphrey \| first6 = PA. \| last7 = van der Kwast \| first7 = T. \| last8 = Montironi \| first8 = R. \| last9 = Delahunt \| first9 = B. \| title = International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 4: seminal vesicles and lymph nodes. \| journal = Mod Pathol \| volume = 24 \| issue = 1 \| pages = 39-47 \| month = Jan \| year = 2011 \| doi = 10.1038/modpathol.2010.160 \| PMID = 20818343 }}</ref>
	**All lymph nodes should be submitted.		**All lymph nodes should be submitted.
	***[[Lymph node metastasis\|Metastases]] are found in over 5% of tissue not grossly recognized as a lymph node;<ref name=pmid3773097>{{Cite journal \| last1 = Epstein \| first1 = JI. \| last2 = Oesterling \| first2 = JE. \| last3 = Eggleston \| first3 = JC. \| last4 = Walsh \| first4 = PC. \| title = Frozen section detection of lymph node metastases in prostatic carcinoma: accuracy in grossly uninvolved pelvic lymphadenectomy specimens. \| journal = J Urol \| volume = 136 \| issue = 6 \| pages = 1234-7 \| month = Dec \| year = 1986 \| doi = \| PMID = 3773097 }}</ref> thus, it ~~makes sense~~ to submit all tissue.<ref>{{Cite journal \| last1 = Sung \| first1 = MT. \| last2 = davidson \| first2 = DD. \| last3 = Montironi \| first3 = R. \| last4 = Lopez-Beltran \| first4 = A. \| last5 = Cheng \| first4 = L. \| title = Radical prostatectomy specimen processing: a critical appraisal of sampling methods. \| journal = Current Diagnostic Pathology \| volume = 13 \| issue = \| pages = 490-498 \| month = \| year = 2007 \| doi = \| PMID = \| URL = http://www.journals.elsevierhealth.com/periodicals/ycdip/article/S0968-6053(07)00074-9/abstract }} </ref>		***59% of the the ISUP panel on the topic believe submitting all of the the lymph nodes (without the surrounding fat) is sufficient.<ref name=pmid20818343/>
			***[[Lymph node metastasis\|Metastases]] are found in over 5% of tissue not grossly recognized as a lymph node (at frozen section);<ref name=pmid3773097>{{Cite journal \| last1 = Epstein \| first1 = JI. \| last2 = Oesterling \| first2 = JE. \| last3 = Eggleston \| first3 = JC. \| last4 = Walsh \| first4 = PC. \| title = Frozen section detection of lymph node metastases in prostatic carcinoma: accuracy in grossly uninvolved pelvic lymphadenectomy specimens. \| journal = J Urol \| volume = 136 \| issue = 6 \| pages = 1234-7 \| month = Dec \| year = 1986 \| doi = \| PMID = 3773097 }}</ref> thus, it is reasonable to submit all of the tissue.<ref>{{Cite journal \| last1 = Sung \| first1 = MT. \| last2 = davidson \| first2 = DD. \| last3 = Montironi \| first3 = R. \| last4 = Lopez-Beltran \| first4 = A. \| last5 = Cheng \| first4 = L. \| title = Radical prostatectomy specimen processing: a critical appraisal of sampling methods. \| journal = Current Diagnostic Pathology \| volume = 13 \| issue = \| pages = 490-498 \| month = \| year = 2007 \| doi = \| PMID = \| URL = http://www.journals.elsevierhealth.com/periodicals/ycdip/article/S0968-6053(07)00074-9/abstract }} </ref>
	*Seminal vesicles (SV):<ref name=pmid20818343/>		*Seminal vesicles (SV):<ref name=pmid20818343/>
	**The base of the SV (adjacent to SV-prostate junction) must be submitted.		**The base of the SV (adjacent to SV-prostate junction) must be submitted.

Michael: /* Literature */

2015-10-28T15:12:00Z

Literature

← Older revision		Revision as of 15:12, 28 October 2015
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	**The prostate should be weighted after trimming the seminal vesicles.		**The prostate should be weighted after trimming the seminal vesicles.
	**The apex of the prostate and the bladder neck should be sliced-off, sagittally sectioned, and submitted separately on edge (to assess the margin).		**The apex of the prostate and the bladder neck should be sliced-off, sagittally sectioned, and submitted separately on edge (to assess the margin).
	*Lymph ~~nodes~~:<ref name=pmid20818343>{{Cite journal \| last1 = Berney \| first1 = DM. \| last2 = Wheeler \| first2 = TM. \| last3 = Grignon \| first3 = DJ. \| last4 = Epstein \| first4 = JI. \| last5 = Griffiths \| first5 = DF. \| last6 = Humphrey \| first6 = PA. \| last7 = van der Kwast \| first7 = T. \| last8 = Montironi \| first8 = R. \| last9 = Delahunt \| first9 = B. \| title = International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 4: seminal vesicles and lymph nodes. \| journal = Mod Pathol \| volume = 24 \| issue = 1 \| pages = 39-47 \| month = Jan \| year = 2011 \| doi = 10.1038/modpathol.2010.160 \| PMID = 20818343 }}</ref>		*[[Lymph node]]s:<ref name=pmid20818343>{{Cite journal \| last1 = Berney \| first1 = DM. \| last2 = Wheeler \| first2 = TM. \| last3 = Grignon \| first3 = DJ. \| last4 = Epstein \| first4 = JI. \| last5 = Griffiths \| first5 = DF. \| last6 = Humphrey \| first6 = PA. \| last7 = van der Kwast \| first7 = T. \| last8 = Montironi \| first8 = R. \| last9 = Delahunt \| first9 = B. \| title = International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 4: seminal vesicles and lymph nodes. \| journal = Mod Pathol \| volume = 24 \| issue = 1 \| pages = 39-47 \| month = Jan \| year = 2011 \| doi = 10.1038/modpathol.2010.160 \| PMID = 20818343 }}</ref>
	**All lymph nodes should be submitted.		**All lymph nodes should be submitted.
	***Metastases are found in over 5% of tissue not grossly recognized as a lymph node;<ref name=pmid3773097>{{Cite journal \| last1 = Epstein \| first1 = JI. \| last2 = Oesterling \| first2 = JE. \| last3 = Eggleston \| first3 = JC. \| last4 = Walsh \| first4 = PC. \| title = Frozen section detection of lymph node metastases in prostatic carcinoma: accuracy in grossly uninvolved pelvic lymphadenectomy specimens. \| journal = J Urol \| volume = 136 \| issue = 6 \| pages = 1234-7 \| month = Dec \| year = 1986 \| doi = \| PMID = 3773097 }}</ref> thus, it makes sense to submit all tissue.<ref>{{Cite journal \| last1 = Sung \| first1 = MT. \| last2 = davidson \| first2 = DD. \| last3 = Montironi \| first3 = R. \| last4 = Lopez-Beltran \| first4 = A. \| last5 = Cheng \| first4 = L. \| title = Radical prostatectomy specimen processing: a critical appraisal of sampling methods. \| journal = Current Diagnostic Pathology \| volume = 13 \| issue = \| pages = 490-498 \| month = \| year = 2007 \| doi = \| PMID = \| URL = http://www.journals.elsevierhealth.com/periodicals/ycdip/article/S0968-6053(07)00074-9/abstract }} </ref>		***[[Lymph node metastasis\|Metastases]] are found in over 5% of tissue not grossly recognized as a lymph node;<ref name=pmid3773097>{{Cite journal \| last1 = Epstein \| first1 = JI. \| last2 = Oesterling \| first2 = JE. \| last3 = Eggleston \| first3 = JC. \| last4 = Walsh \| first4 = PC. \| title = Frozen section detection of lymph node metastases in prostatic carcinoma: accuracy in grossly uninvolved pelvic lymphadenectomy specimens. \| journal = J Urol \| volume = 136 \| issue = 6 \| pages = 1234-7 \| month = Dec \| year = 1986 \| doi = \| PMID = 3773097 }}</ref> thus, it makes sense to submit all tissue.<ref>{{Cite journal \| last1 = Sung \| first1 = MT. \| last2 = davidson \| first2 = DD. \| last3 = Montironi \| first3 = R. \| last4 = Lopez-Beltran \| first4 = A. \| last5 = Cheng \| first4 = L. \| title = Radical prostatectomy specimen processing: a critical appraisal of sampling methods. \| journal = Current Diagnostic Pathology \| volume = 13 \| issue = \| pages = 490-498 \| month = \| year = 2007 \| doi = \| PMID = \| URL = http://www.journals.elsevierhealth.com/periodicals/ycdip/article/S0968-6053(07)00074-9/abstract }} </ref>
	*Seminal vesicles (SV):<ref name=pmid20818343/>		*Seminal vesicles (SV):<ref name=pmid20818343/>
	**The base of the SV (adjacent to SV-prostate junction) must be submitted.		**The base of the SV (adjacent to SV-prostate junction) must be submitted.

Michael: /* Literature */

2015-10-28T14:57:16Z

Literature

← Older revision		Revision as of 14:57, 28 October 2015
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	**The prostate should be weighted after trimming the seminal vesicles.		**The prostate should be weighted after trimming the seminal vesicles.
	**The apex of the prostate and the bladder neck should be sliced-off, sagittally sectioned, and submitted separately on edge (to assess the margin).		**The apex of the prostate and the bladder neck should be sliced-off, sagittally sectioned, and submitted separately on edge (to assess the margin).
	*Lymph nodes ~~and seminal vesicles (SV)~~:<ref name=pmid20818343>{{Cite journal \| last1 = Berney \| first1 = DM. \| last2 = Wheeler \| first2 = TM. \| last3 = Grignon \| first3 = DJ. \| last4 = Epstein \| first4 = JI. \| last5 = Griffiths \| first5 = DF. \| last6 = Humphrey \| first6 = PA. \| last7 = van der Kwast \| first7 = T. \| last8 = Montironi \| first8 = R. \| last9 = Delahunt \| first9 = B. \| title = International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 4: seminal vesicles and lymph nodes. \| journal = Mod Pathol \| volume = 24 \| issue = 1 \| pages = 39-47 \| month = Jan \| year = 2011 \| doi = 10.1038/modpathol.2010.160 \| PMID = 20818343 }}</ref>		*Lymph nodes:<ref name=pmid20818343>{{Cite journal \| last1 = Berney \| first1 = DM. \| last2 = Wheeler \| first2 = TM. \| last3 = Grignon \| first3 = DJ. \| last4 = Epstein \| first4 = JI. \| last5 = Griffiths \| first5 = DF. \| last6 = Humphrey \| first6 = PA. \| last7 = van der Kwast \| first7 = T. \| last8 = Montironi \| first8 = R. \| last9 = Delahunt \| first9 = B. \| title = International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 4: seminal vesicles and lymph nodes. \| journal = Mod Pathol \| volume = 24 \| issue = 1 \| pages = 39-47 \| month = Jan \| year = 2011 \| doi = 10.1038/modpathol.2010.160 \| PMID = 20818343 }}</ref>
	**All lymph nodes should be submitted.		**All lymph nodes should be submitted.
	***Metastases are found in over 5% of tissue not grossly recognized as a lymph node;<ref name=pmid3773097>{{Cite journal \| last1 = Epstein \| first1 = JI. \| last2 = Oesterling \| first2 = JE. \| last3 = Eggleston \| first3 = JC. \| last4 = Walsh \| first4 = PC. \| title = Frozen section detection of lymph node metastases in prostatic carcinoma: accuracy in grossly uninvolved pelvic lymphadenectomy specimens. \| journal = J Urol \| volume = 136 \| issue = 6 \| pages = 1234-7 \| month = Dec \| year = 1986 \| doi = \| PMID = 3773097 }}</ref> thus, it makes sense to submit all tissue.<ref>{{Cite journal \| last1 = Sung \| first1 = MT. \| last2 = davidson \| first2 = DD. \| last3 = Montironi \| first3 = R. \| last4 = Lopez-Beltran \| first4 = A. \| last5 = Cheng \| first4 = L. \| title = Radical prostatectomy specimen processing: a critical appraisal of sampling methods. \| journal = Current Diagnostic Pathology \| volume = 13 \| issue = \| pages = 490-498 \| month = \| year = 2007 \| doi = \| PMID = \| URL = http://www.journals.elsevierhealth.com/periodicals/ycdip/article/S0968-6053(07)00074-9/abstract }} </ref>		***Metastases are found in over 5% of tissue not grossly recognized as a lymph node;<ref name=pmid3773097>{{Cite journal \| last1 = Epstein \| first1 = JI. \| last2 = Oesterling \| first2 = JE. \| last3 = Eggleston \| first3 = JC. \| last4 = Walsh \| first4 = PC. \| title = Frozen section detection of lymph node metastases in prostatic carcinoma: accuracy in grossly uninvolved pelvic lymphadenectomy specimens. \| journal = J Urol \| volume = 136 \| issue = 6 \| pages = 1234-7 \| month = Dec \| year = 1986 \| doi = \| PMID = 3773097 }}</ref> thus, it makes sense to submit all tissue.<ref>{{Cite journal \| last1 = Sung \| first1 = MT. \| last2 = davidson \| first2 = DD. \| last3 = Montironi \| first3 = R. \| last4 = Lopez-Beltran \| first4 = A. \| last5 = Cheng \| first4 = L. \| title = Radical prostatectomy specimen processing: a critical appraisal of sampling methods. \| journal = Current Diagnostic Pathology \| volume = 13 \| issue = \| pages = 490-498 \| month = \| year = 2007 \| doi = \| PMID = \| URL = http://www.journals.elsevierhealth.com/periodicals/ycdip/article/S0968-6053(07)00074-9/abstract }} </ref>
	**The base of the SV/prostate junction must be submitted.		*Seminal vesicles (SV):<ref name=pmid20818343/>
			**The base of the SV (adjacent to SV-prostate junction) must be submitted.
			***Only ''extraprostatic seminal vesicle involvement'' is considered ''seminal vesicle invasion''.
	***SV does ''not'' have to be [[submitted in total]].		***SV does ''not'' have to be [[submitted in total]].

Michael: /* Procedural */

2015-10-28T14:55:01Z

Procedural

← Older revision		Revision as of 14:55, 28 October 2015
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	====Procedural====		====Procedural====
	#Amputate seminal vesicles (SV) after inking.		#Amputate seminal vesicles (SV) after inking.
	#*Sections of the SV base should be cut perpendicular the (long) axis of the gland.		#*Sections of the SV base (from the amputated SV) should be cut perpendicular the (long) axis of the gland.
	#Bladder neck margin is submitted on edge.		#Bladder neck margin is submitted on edge.
	#*A slice is cut-off the prostate at the site of the bladder neck margin. This slice is then divided into left and right with a sagittal cut. Each portion (left and right) is sectioned with parasagittal cuts such that it is submitted as an [[on edge margin]].		#*A slice is cut-off the prostate at the site of the bladder neck margin. This slice is then divided into left and right with a sagittal cut. Each portion (left and right) is sectioned with parasagittal cuts such that it is submitted as an [[on edge margin]].

Michael: /* Protocol */

2014-11-21T18:46:37Z

Protocol

← Older revision		Revision as of 18:46, 21 November 2014
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	**Left (superior-inferior (long axis), left-to-right, anterior-posterior): ___ cm.		**Left (superior-inferior (long axis), left-to-right, anterior-posterior): ___ cm.
	**Right (superior-inferior (long axis), left-to-right, anterior-posterior): ___ cm.		**Right (superior-inferior (long axis), left-to-right, anterior-posterior): ___ cm.
	*Inking scheme: ~~left~~ - blue; right - ~~green~~.		*Inking scheme: green - anterior prostate, blue - right prostate, black - left prostate.

	Submitted in total:		Submitted in total:

Michael: /* Related protocols */

2014-09-22T06:47:50Z

Related protocols

← Older revision		Revision as of 06:47, 22 September 2014
Line 56:		Line 56:
	*[[Prostate biopsy]].		*[[Prostate biopsy]].
	*[[Prostate chips]].		*[[Prostate chips]].
	*[[~~Radical cystoprostatectomy~~]].		*[[Cystoprostatectomy]].

	==References==		==References==

Michael: /* Related protocols */

2014-09-22T06:41:04Z

Related protocols

← Older revision		Revision as of 06:41, 22 September 2014
Line 56:		Line 56:
	*[[Prostate biopsy]].		*[[Prostate biopsy]].
	*[[Prostate chips]].		*[[Prostate chips]].
			*[[Radical cystoprostatectomy]].

	==References==		==References==

Michael: /* Protocol */

2014-07-28T04:44:32Z

Protocol

← Older revision		Revision as of 04:44, 28 July 2014
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	*Prostate dimensions (superior-inferior, left-to-right, anterior-posterior): ___ x ___ x ___ cm.		*Prostate dimensions (superior-inferior, left-to-right, anterior-posterior): ___ x ___ x ___ cm.
	*Seminal vesicles:		*Seminal vesicles:
	**Left (superior-inferior (long axis), , left-to-right, anterior-posterior): ___ cm.		**Left (superior-inferior (long axis), left-to-right, anterior-posterior): ___ cm.
	**Right (superior-inferior (long axis), , left-to-right, anterior-posterior): ___ cm.		**Right (superior-inferior (long axis), left-to-right, anterior-posterior): ___ cm.
	*Inking scheme: left - blue; right - green.		*Inking scheme: left - blue; right - green.