Renal cell carcinoma with rhabdoid morphology - Revision history

Michael: /* General */

2019-04-04T20:04:19Z

General

← Older revision		Revision as of 20:04, 4 April 2019
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	*Not recognized as a distinct entity.<ref name=pmid21665507>{{Cite journal \| last1 = Chapman-Fredricks \| first1 = JR. \| last2 = Herrera \| first2 = L. \| last3 = Bracho \| first3 = J. \| last4 = Gomez-Fernandez \| first4 = C. \| last5 = Leveillee \| first5 = R. \| last6 = Rey \| first6 = L. \| last7 = Jorda \| first7 = M. \| title = Adult renal cell carcinoma with rhabdoid morphology represents a neoplastic dedifferentiation analogous to sarcomatoid carcinoma. \| journal = Ann Diagn Pathol \| volume = 15 \| issue = 5 \| pages = 333-7 \| month = Oct \| year = 2011 \| doi = 10.1016/j.anndiagpath.2011.03.002 \| PMID = 21665507 }}</ref>		*Not recognized as a distinct entity.<ref name=pmid21665507>{{Cite journal \| last1 = Chapman-Fredricks \| first1 = JR. \| last2 = Herrera \| first2 = L. \| last3 = Bracho \| first3 = J. \| last4 = Gomez-Fernandez \| first4 = C. \| last5 = Leveillee \| first5 = R. \| last6 = Rey \| first6 = L. \| last7 = Jorda \| first7 = M. \| title = Adult renal cell carcinoma with rhabdoid morphology represents a neoplastic dedifferentiation analogous to sarcomatoid carcinoma. \| journal = Ann Diagn Pathol \| volume = 15 \| issue = 5 \| pages = 333-7 \| month = Oct \| year = 2011 \| doi = 10.1016/j.anndiagpath.2011.03.002 \| PMID = 21665507 }}</ref>
	*[[ISUP nucleolar grade]] 4 by definition.		*[[ISUP nucleolar grade]] 4 by definition.
			*May be seen in [[ALK translocation renal cell carcinoma]].<ref name=pmid26017874>{{Cite journal \| last1 = Kuroda \| first1 = N. \| last2 = Karashima \| first2 = T. \| last3 = Inoue \| first3 = K. \| last4 = Kasajima \| first4 = A. \| last5 = Ohe \| first5 = C. \| last6 = Kawakami \| first6 = F. \| last7 = Mikami \| first7 = S. \| last8 = Matsuura \| first8 = K. \| last9 = Moriyama \| first9 = M. \| title = Review of renal cell carcinoma with rhabdoid features with focus on clinical and pathobiological aspects. \| journal = Pol J Pathol \| volume = 66 \| issue = 1 \| pages = 3-8 \| month = Mar \| year = 2015 \| doi = \| PMID = 26017874 }}</ref>

	==Microscopic==		==Microscopic==

Michael at 19:43, 20 February 2015

2015-02-20T19:43:51Z

← Older revision		Revision as of 19:43, 20 February 2015
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	[[Image: Renal cell carcinoma with rhabdoid change -- intermed mag.jpg\|thumb\|300px\|[[Micrograph]] showing rhabdoid change in a renal cell carcinoma. [[H&E stain]].]]		[[Image: Renal cell carcinoma with rhabdoid change -- intermed mag.jpg\|thumb\|300px\|[[Micrograph]] showing rhabdoid change in a renal cell carcinoma. [[H&E stain]].]]
	'''Renal cell carcinoma with rhabdoid morphology''' is an uncommon finding with a poor prognosis. It is also known as '''renal cell carcinoma with rhabdoid change'''.		'''Renal cell carcinoma with rhabdoid morphology''' is an uncommon finding with a poor prognosis. It is also known as '''renal cell carcinoma with rhabdoid change'''.

			It should '''not''' be confused with [[renal rhabdoid tumour]].

	==General==		==General==

Michael: /* General */

2015-02-17T06:47:07Z

General

← Older revision		Revision as of 06:47, 17 February 2015
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	==General==		==General==
	*Not recognized as a distinct entity.<ref name=pmid21665507>{{Cite journal \| last1 = Chapman-Fredricks \| first1 = JR. \| last2 = Herrera \| first2 = L. \| last3 = Bracho \| first3 = J. \| last4 = Gomez-Fernandez \| first4 = C. \| last5 = Leveillee \| first5 = R. \| last6 = Rey \| first6 = L. \| last7 = Jorda \| first7 = M. \| title = Adult renal cell carcinoma with rhabdoid morphology represents a neoplastic dedifferentiation analogous to sarcomatoid carcinoma. \| journal = Ann Diagn Pathol \| volume = 15 \| issue = 5 \| pages = 333-7 \| month = Oct \| year = 2011 \| doi = 10.1016/j.anndiagpath.2011.03.002 \| PMID = 21665507 }}</ref>		*Not recognized as a distinct entity.<ref name=pmid21665507>{{Cite journal \| last1 = Chapman-Fredricks \| first1 = JR. \| last2 = Herrera \| first2 = L. \| last3 = Bracho \| first3 = J. \| last4 = Gomez-Fernandez \| first4 = C. \| last5 = Leveillee \| first5 = R. \| last6 = Rey \| first6 = L. \| last7 = Jorda \| first7 = M. \| title = Adult renal cell carcinoma with rhabdoid morphology represents a neoplastic dedifferentiation analogous to sarcomatoid carcinoma. \| journal = Ann Diagn Pathol \| volume = 15 \| issue = 5 \| pages = 333-7 \| month = Oct \| year = 2011 \| doi = 10.1016/j.anndiagpath.2011.03.002 \| PMID = 21665507 }}</ref>
			*[[ISUP nucleolar grade]] 4 by definition.

	==Microscopic==		==Microscopic==

Michael: /* See also */

2015-02-17T06:44:56Z

Michael: /* See also */

2014-11-09T04:12:06Z

Michael: /* Sign out */

2014-11-03T16:06:41Z

Sign out

← Older revision		Revision as of 16:06, 3 November 2014
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	<pre>		<pre>
	MASS, RIGHT KIDNEY, RADICAL NEPHRECTOMY:		MASS, RIGHT KIDNEY, RADICAL NEPHRECTOMY:
	- CLEAR CELL RENAL CELL CARCINOMA, ~~FUHRMAN~~ GRADE 4, pT1b, pNX.		- CLEAR CELL RENAL CELL CARCINOMA, ISUP NUCLEOLAR GRADE 4, pT1b, pNX.
	-- RHABDOID CHANGE PRESENT, SEE COMMENT.		-- RHABDOID CHANGE PRESENT, SEE COMMENT.
	-- MARGINS NEGATIVE FOR MALIGNANCY.		-- MARGINS NEGATIVE FOR MALIGNANCY.
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	Rhabdoid change is considered by some to be analogous to sarcomatoid		Rhabdoid change is considered by some to be analogous to sarcomatoid
	change.[1] The rhabdoid change in this case represents approximately		change.[1] The rhabdoid change in this case represents approximately
	35% of the tumour, and has ~~Fuhrman~~ grade 4 nuclear features.		35% of the tumour, and has ISUP nucleolar grade 4 nuclear features.

	1. Ann Diagn Pathol. 2011 Oct;15(5):333-7.		1. Ann Diagn Pathol. 2011 Oct;15(5):333-7.

Michael at 06:16, 4 August 2014

2014-08-04T06:16:35Z

← Older revision		Revision as of 06:16, 4 August 2014
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			[[Image: Renal cell carcinoma with rhabdoid change -- intermed mag.jpg\|thumb\|300px\|[[Micrograph]] showing rhabdoid change in a renal cell carcinoma. [[H&E stain]].]]
	'''Renal cell carcinoma with rhabdoid morphology''' is an uncommon finding with a poor prognosis. It is also known as '''renal cell carcinoma with rhabdoid change'''.		'''Renal cell carcinoma with rhabdoid morphology''' is an uncommon finding with a poor prognosis. It is also known as '''renal cell carcinoma with rhabdoid change'''.

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	Notes:		Notes:
	*May be multinucleated.		*May be multinucleated.

			===Images===
			<gallery>
			Image: Renal cell carcinoma with rhabdoid change -- low mag.jpg \| RCC with RC - low mag.
			Image: Renal cell carcinoma with rhabdoid change -- intermed mag.jpg \| RCC with RC - intermed. mag.
			Image: Renal cell carcinoma with rhabdoid change -- high mag.jpg \| RCC with RC - high mag.
			Image: Renal cell carcinoma with rhabdoid change -- very high mag.jpg \| RCC with RC - very high mag.
			Image: Renal cell carcinoma with rhabdoid change - alt -- very high mag.jpg \| RCC with RC - very high mag.
			</gallery>

	==IHC==		==IHC==

Michael: +SO

2014-04-29T19:40:20Z

+SO

← Older revision		Revision as of 19:40, 29 April 2014
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	*Desmin -ve (23 of 23 cases).		*Desmin -ve (23 of 23 cases).
	*SMA -ve (~5% of cases).		*SMA -ve (~5% of cases).

			==Sign out==
			<pre>
			MASS, RIGHT KIDNEY, RADICAL NEPHRECTOMY:
			- CLEAR CELL RENAL CELL CARCINOMA, FUHRMAN GRADE 4, pT1b, pNX.
			-- RHABDOID CHANGE PRESENT, SEE COMMENT.
			-- MARGINS NEGATIVE FOR MALIGNANCY.
			-- PLEASE SEE TUMOUR SUMMARY.

			COMMENT:
			Rhabdoid change is considered by some to be analogous to sarcomatoid
			change.[1] The rhabdoid change in this case represents approximately
			35% of the tumour, and has Fuhrman grade 4 nuclear features.

			1. Ann Diagn Pathol. 2011 Oct;15(5):333-7.
			</pre>

	==See also==		==See also==

Michael: /* Microscopic */

2014-04-29T19:32:59Z

Microscopic

← Older revision		Revision as of 19:32, 29 April 2014
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	Features:		Features:
	*[[Rhabdoid cells]]:		*[[Rhabdoid cells]]:
	**Eccentrically placed large round nuclei with ~~very prominent nucleoli~~.		**Eccentrically placed large round nuclei with abundant eosinophilic cytoplasm.
	**~~Abundant eosinophilic cytoplasm~~.		**+/-Very prominent [[nucleolus]].

	Notes:		Notes:

Michael: /* See also */

2014-04-29T19:31:49Z

← Older revision		Revision as of 06:44, 17 February 2015
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	==See also==		==See also==
	*[[Renal cell carcinoma]].		*[[Renal cell carcinoma]].
			*[[Renal cell carcinoma with sarcomatoid differentiation]].
	*[[Rhabdoid]].		*[[Rhabdoid]].
	*[[ISUP nucleolar grade]].		*[[ISUP nucleolar grade]].

← Older revision		Revision as of 04:12, 9 November 2014
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	*[[Renal cell carcinoma]].		*[[Renal cell carcinoma]].
	*[[Rhabdoid]].		*[[Rhabdoid]].
			*[[ISUP nucleolar grade]].

	==References==		==References==

← Older revision		Revision as of 19:31, 29 April 2014
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	==See also==		==See also==
	*[[Renal cell carcinoma]].		*[[Renal cell carcinoma]].
			*[[Rhabdoid]].

	==References==		==References==