Secretory carcinoma of the salivary gland - Revision history

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2021-11-02T20:53:57Z

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	NTRK testing was ordered; the results will be reported in an addendum.		NTRK testing was ordered; the results will be reported in an addendum.
	</pre>		</pre>

			===Micro===
			The sections show a cohesive tumor with moderate amphophilic cytoplasm and vacuolation. The vacuolation is focally prominent. Nucleoli are inconspicuous. Poorly formed glands are present. Keratinization is absent.

	==See also==		==See also==

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2021-11-02T20:50:00Z

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	The tumour stains as follows:		The tumour stains as follows:
	POSITIVE: CK7 (strong, diffuse), mammaglobin (strong, diffuse), S100 (moderate, patchy), mucin (~~very~~ focal).		POSITIVE: CK7 (strong, diffuse), mammaglobin (strong, diffuse), S100 (moderate, patchy), mucin (focal).
	NEGATIVE: p63.		NEGATIVE: p63.

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2021-11-02T20:48:47Z

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	Note:		Note:
	*The translocation seen in [[secretory breast carcinoma]], [[congenital-infantile fibrosarcoma]] and [[mesoblastic nephroma]].		*The translocation seen in [[secretory breast carcinoma]], [[congenital-infantile fibrosarcoma]] and [[mesoblastic nephroma]].

			==Sign out==
			<pre>
			Right Parotid Lesion, Core Biopsy:
			- SECRETORY CARCINOMA of the salivary gland, see comment.

			Comment:
			Secretory carcinoma of the salivary gland was previously known as "mammary analogue secretory carcinoma" (MASC).

			The tumour stains as follows:
			POSITIVE: CK7 (strong, diffuse), mammaglobin (strong, diffuse), S100 (moderate, patchy), mucin (very focal).
			NEGATIVE: p63.

			NTRK testing was ordered; the results will be reported in an addendum.
			</pre>

	==See also==		==See also==

Michael: fix

2021-10-27T16:40:31Z

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	===Images===		===Images===
	<gallery>		<gallery>
	Image:Mammary_analogue_secretory_carcinoma_(mammaglobin_immunohistochemstry,_medium_power).jpg \| MASC - ~~mammaglobulin~~. (WC/NormanDy)		Image:Mammary_analogue_secretory_carcinoma_(mammaglobin_immunohistochemstry,_medium_power).jpg \| MASC - mammaglobin. (WC/NormanDy)
	Image:Mammary_analogue_secretory_carcinoma_(S100immunohistochemstry,_low_power).jpg \| MASC - S-100. (WC/NormanDy)		Image:Mammary_analogue_secretory_carcinoma_(S100immunohistochemstry,_low_power).jpg \| MASC - S-100. (WC/NormanDy)
	</gallery>		</gallery>

Michael: vauthors

2020-05-24T20:31:10Z

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	'''Secretory carcinoma of the salivary gland''' is an uncommon [[malignant]] [[salivary gland]] tumour that was first described in 2010.<ref name=pmid22127547>{{Cite journal \| last1 = Lei \| first1 = Y. \| last2 = Chiosea \| first2 = SI. \| title = Re-evaluating historic cohort of salivary acinic cell carcinoma with new diagnostic tools. \| journal = Head Neck Pathol \| volume = 6 \| issue = 2 \| pages = 166-70 \| month = Jun \| year = 2012 \| doi = 10.1007/s12105-011-0312-9 \| PMID = 22127547 }}</ref>		'''Secretory carcinoma of the salivary gland''' is an uncommon [[malignant]] [[salivary gland]] tumour that was first described in 2010.<ref name=pmid22127547>{{Cite journal \| last1 = Lei \| first1 = Y. \| last2 = Chiosea \| first2 = SI. \| title = Re-evaluating historic cohort of salivary acinic cell carcinoma with new diagnostic tools. \| journal = Head Neck Pathol \| volume = 6 \| issue = 2 \| pages = 166-70 \| month = Jun \| year = 2012 \| doi = 10.1007/s12105-011-0312-9 \| PMID = 22127547 }}</ref>

	It was previously known as '''mammary analogue secretory carcinoma''', abbreviated '''MASC'''.<ref name=pmid31007960>{{cite journal \|~~vauthors~~=Montalvo N, Galarza D, Redrobán L \|title=Secretory Carcinoma of the Parotid: Making the Correct Diagnosis of a Rare Salivary Gland Carcinoma When Molecular Biology Testing Is Not Available \|journal=Case Rep Pathol \|volume=2019 \|issue= \|pages=5103496 \|date=2019 \|pmid=31007960 \|pmc=6441535 \|doi=10.1155/2019/5103496 \|url=}}</ref>		It was previously known as '''mammary analogue secretory carcinoma''', abbreviated '''MASC'''.<ref name=pmid31007960>{{cite journal \|authors=Montalvo N, Galarza D, Redrobán L \|title=Secretory Carcinoma of the Parotid: Making the Correct Diagnosis of a Rare Salivary Gland Carcinoma When Molecular Biology Testing Is Not Available \|journal=Case Rep Pathol \|volume=2019 \|issue= \|pages=5103496 \|date=2019 \|pmid=31007960 \|pmc=6441535 \|doi=10.1155/2019/5103496 \|url=}}</ref>

	==General==		==General==

Michael: /* Images */

2020-05-24T00:57:48Z

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	===Images===		===Images===
			====Case 1====
	<gallery>		<gallery>
	Image:Mammary_analogue_secretory_carcinoma_(H%26E,_low_power).jpg \| SC - low. (WC/NormanDy)		Image:Mammary_analogue_secretory_carcinoma_(H%26E,_low_power).jpg \| SC - low. (WC/NormanDy)
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	Image:Mammary_analogue_secretory_carcinoma_(H%26E,_high_power),_solid.jpg \| SC - high solid. (WC/NormanDy)		Image:Mammary_analogue_secretory_carcinoma_(H%26E,_high_power),_solid.jpg \| SC - high solid. (WC/NormanDy)
	</gallery>		</gallery>
			====Case 2====
			<gallery>
			Image: Secretory carcinoma of salivary gland -- low mag.jpg \| SCSG - low mag. (WC)
			Image: Secretory carcinoma of salivary gland -- intermed mag.jpg \| SCSG - intermed. mag. (WC)
			Image: Secretory carcinoma of salivary gland -- high mag.jpg \| SCSG - high mag. (WC)
			Image: Secretory carcinoma of salivary gland - alt -- high mag.jpg \| SCSG - high mag. (WC)
			</gallery>

	====www====		====www====
	*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370021/figure/Fig2/ MASC (nih.gov)].<ref name=pmid22127547/>		*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370021/figure/Fig2/ MASC (nih.gov)].<ref name=pmid22127547/>

Michael: tweka

2019-12-31T15:17:48Z

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	\| Tx = excision		\| Tx = excision
	}}		}}
	'''Secretory carcinoma of the salivary gland''' is ~~rare a newly described~~ [[malignant]] [[salivary gland]] tumour.<ref name=pmid22127547>{{Cite journal \| last1 = Lei \| first1 = Y. \| last2 = Chiosea \| first2 = SI. \| title = Re-evaluating historic cohort of salivary acinic cell carcinoma with new diagnostic tools. \| journal = Head Neck Pathol \| volume = 6 \| issue = 2 \| pages = 166-70 \| month = Jun \| year = 2012 \| doi = 10.1007/s12105-011-0312-9 \| PMID = 22127547 }}</ref>		'''Secretory carcinoma of the salivary gland''' is an uncommon [[malignant]] [[salivary gland]] tumour that was first described in 2010.<ref name=pmid22127547>{{Cite journal \| last1 = Lei \| first1 = Y. \| last2 = Chiosea \| first2 = SI. \| title = Re-evaluating historic cohort of salivary acinic cell carcinoma with new diagnostic tools. \| journal = Head Neck Pathol \| volume = 6 \| issue = 2 \| pages = 166-70 \| month = Jun \| year = 2012 \| doi = 10.1007/s12105-011-0312-9 \| PMID = 22127547 }}</ref>

	It was previously known as '''mammary analogue secretory carcinoma''', abbreviated '''MASC'''.<ref name=pmid31007960>{{cite journal \|vauthors=Montalvo N, Galarza D, Redrobán L \|title=Secretory Carcinoma of the Parotid: Making the Correct Diagnosis of a Rare Salivary Gland Carcinoma When Molecular Biology Testing Is Not Available \|journal=Case Rep Pathol \|volume=2019 \|issue= \|pages=5103496 \|date=2019 \|pmid=31007960 \|pmc=6441535 \|doi=10.1155/2019/5103496 \|url=}}</ref>		It was previously known as '''mammary analogue secretory carcinoma''', abbreviated '''MASC'''.<ref name=pmid31007960>{{cite journal \|vauthors=Montalvo N, Galarza D, Redrobán L \|title=Secretory Carcinoma of the Parotid: Making the Correct Diagnosis of a Rare Salivary Gland Carcinoma When Molecular Biology Testing Is Not Available \|journal=Case Rep Pathol \|volume=2019 \|issue= \|pages=5103496 \|date=2019 \|pmid=31007960 \|pmc=6441535 \|doi=10.1155/2019/5103496 \|url=}}</ref>

Michael: /* See also */

2019-12-31T15:16:35Z

Michael: tweak

2019-12-31T15:13:49Z

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← Older revision		Revision as of 15:13, 31 December 2019
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	===Images===		===Images===
	<gallery>		<gallery>
	Image:Mammary_analogue_secretory_carcinoma_(H%26E,_low_power).jpg \| ~~MASC~~ - low. (WC/NormanDy)		Image:Mammary_analogue_secretory_carcinoma_(H%26E,_low_power).jpg \| SC - low. (WC/NormanDy)
	Image:Mammary_analogue_secretory_carcinoma_(H%26E,_medium_power).jpg \| ~~MASC~~ - med. (WC/NormanDy)		Image:Mammary_analogue_secretory_carcinoma_(H%26E,_medium_power).jpg \| SC - med. (WC/NormanDy)
	Image:Mammary_analogue_secretory_carcinoma_(H%26E,_high_power).jpg \| ~~MASC~~ - high. (WC/NormanDy)		Image:Mammary_analogue_secretory_carcinoma_(H%26E,_high_power).jpg \| SC - high. (WC/NormanDy)
	Image:Mammary_analogue_secretory_carcinoma_(H%26E,_high_power),_solid.jpg \| ~~MAS~~ - high solid. (WC/NormanDy)		Image:Mammary_analogue_secretory_carcinoma_(H%26E,_high_power),_solid.jpg \| SC - high solid. (WC/NormanDy)
	</gallery>		</gallery>
	www:		====www====
	*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370021/figure/Fig2/ MASC (nih.gov)].<ref name=pmid22127547/>		*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370021/figure/Fig2/ MASC (nih.gov)].<ref name=pmid22127547/>
	*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370021/figure/Fig1/ AcCC - the main DDx of MASC (nih.gov)].<ref name=pmid22127547/>		*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3370021/figure/Fig1/ AcCC - the main DDx of MASC (nih.gov)].<ref name=pmid22127547/>

Michael at 15:12, 31 December 2019

2019-12-31T15:12:32Z

← Older revision		Revision as of 15:12, 31 December 2019
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	\| Image = Mammary analogue secretory carcinoma (H&E, medium power).jpg		\| Image = Mammary analogue secretory carcinoma (H&E, medium power).jpg
	\| Width =		\| Width =
	\| Caption = ~~Mammary analogue secretory~~ carcinoma. [[H&E stain]]. (WC/NormanDy)		\| Caption = Secretory carcinoma of the salivary gland. [[H&E stain]]. (WC/NormanDy)
	\| Synonyms =		\| Synonyms = Mammary analogue secretory carcinoma (previous name)
	\| Micro = large cells with abundant cytoplasm, small nuclei, +/-lymphocytic infiltrate, solid and microcystic growth pattern		\| Micro = large cells with abundant cytoplasm, small nuclei, +/-lymphocytic infiltrate, solid and microcystic growth pattern
	\| Subtypes =		\| Subtypes =
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	\| Other =		\| Other =
	\| ClinDDx = other [[salivary gland]] tumours		\| ClinDDx = other [[salivary gland]] tumours
	\| Tx =		\| Tx = excision
	}}		}}
	'''~~Mammary analogue secretory~~ carcinoma'''~~, abbreviated '''MASC''',~~ is a newly described [[malignant]] [[salivary gland]] tumour.<ref name=pmid22127547>{{Cite journal \| last1 = Lei \| first1 = Y. \| last2 = Chiosea \| first2 = SI. \| title = Re-evaluating historic cohort of salivary acinic cell carcinoma with new diagnostic tools. \| journal = Head Neck Pathol \| volume = 6 \| issue = 2 \| pages = 166-70 \| month = Jun \| year = 2012 \| doi = 10.1007/s12105-011-0312-9 \| PMID = 22127547 }}</ref>		'''Secretory carcinoma of the salivary gland''' is rare a newly described [[malignant]] [[salivary gland]] tumour.<ref name=pmid22127547>{{Cite journal \| last1 = Lei \| first1 = Y. \| last2 = Chiosea \| first2 = SI. \| title = Re-evaluating historic cohort of salivary acinic cell carcinoma with new diagnostic tools. \| journal = Head Neck Pathol \| volume = 6 \| issue = 2 \| pages = 166-70 \| month = Jun \| year = 2012 \| doi = 10.1007/s12105-011-0312-9 \| PMID = 22127547 }}</ref>

			It was previously known as '''mammary analogue secretory carcinoma''', abbreviated '''MASC'''.<ref name=pmid31007960>{{cite journal \|vauthors=Montalvo N, Galarza D, Redrobán L \|title=Secretory Carcinoma of the Parotid: Making the Correct Diagnosis of a Rare Salivary Gland Carcinoma When Molecular Biology Testing Is Not Available \|journal=Case Rep Pathol \|volume=2019 \|issue= \|pages=5103496 \|date=2019 \|pmid=31007960 \|pmc=6441535 \|doi=10.1155/2019/5103496 \|url=}}</ref>

	==General==		==General==

← Older revision		Revision as of 15:16, 31 December 2019
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	*[[Salivary gland]].		*[[Salivary gland]].
	*[[Secretory breast carcinoma]].		*[[Secretory breast carcinoma]].
			*[[Secretory carcinoma]].

	==References==		==References==