Serous tubal intraepithelial carcinoma - Revision history

Michael at 05:17, 4 November 2024

2024-11-04T05:17:21Z

← Older revision		Revision as of 05:17, 4 November 2024
Line 59:		Line 59:
	DDx:		DDx:
	*Atypical tubal lesion (STIL or ''tubal intraepithelial lesions in transition'' (TILT)<ref>{{cite journal \|authors=Nishida N, Murakami F, Higaki K \|title=Detection of serous precursor lesions in resected fallopian tubes from patients with benign diseases and a relatively low risk for ovarian cancer \|journal=Pathol Int \|volume=66 \|issue=6 \|pages=337–42 \|date=June 2016 \|pmid=27250113 \|doi=10.1111/pin.12419 \|url=}}</ref>) - lack proliferation.{{fact}}		*Atypical tubal lesion (STIL or ''tubal intraepithelial lesions in transition'' (TILT)<ref>{{cite journal \|authors=Nishida N, Murakami F, Higaki K \|title=Detection of serous precursor lesions in resected fallopian tubes from patients with benign diseases and a relatively low risk for ovarian cancer \|journal=Pathol Int \|volume=66 \|issue=6 \|pages=337–42 \|date=June 2016 \|pmid=27250113 \|doi=10.1111/pin.12419 \|url=}}</ref>) - lack proliferation.{{fact}}
			*[[Serous carcinoma of the fallopian tube]].

	===Images===		===Images===

Michael: /* Microscopic */

2020-12-06T20:16:10Z

Microscopic

← Older revision		Revision as of 20:16, 6 December 2020
Line 58:		Line 58:

	DDx:		DDx:
	*Atypical tubal lesion (STIL or TILT) - lack proliferation.{{fact}}		*Atypical tubal lesion (STIL or ''tubal intraepithelial lesions in transition'' (TILT)<ref>{{cite journal \|authors=Nishida N, Murakami F, Higaki K \|title=Detection of serous precursor lesions in resected fallopian tubes from patients with benign diseases and a relatively low risk for ovarian cancer \|journal=Pathol Int \|volume=66 \|issue=6 \|pages=337–42 \|date=June 2016 \|pmid=27250113 \|doi=10.1111/pin.12419 \|url=}}</ref>) - lack proliferation.{{fact}}

	===Images===		===Images===

Michael at 04:21, 1 January 2020

2020-01-01T04:21:06Z

← Older revision		Revision as of 04:21, 1 January 2020
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	Image: Serous tubal intraepithelial carcinoma - alt -- high mag.jpg \| STIC - high mag. (WC)		Image: Serous tubal intraepithelial carcinoma - alt -- high mag.jpg \| STIC - high mag. (WC)
	Image: Serous tubal intraepithelial carcinoma -- very high mag.jpg \| STIC - very high mag. (WC)		Image: Serous tubal intraepithelial carcinoma -- very high mag.jpg \| STIC - very high mag. (WC)
			</gallery>
			====www====
			*[http://www.nature.com/modpathol/journal/v23/n6/fig_tab/modpathol201060f1.html#figure-title STIC (nature.com)].<ref name=pmid20228782>{{Cite journal \| last1 = Sehdev \| first1 = AS. \| last2 = Kurman \| first2 = RJ. \| last3 = Kuhn \| first3 = E. \| last4 = Shih \| first4 = IeM. \| title = Serous tubal intraepithelial carcinoma upregulates markers associated with high-grade serous carcinomas including Rsf-1 (HBXAP), cyclin E and fatty acid synthase. \| journal = Mod Pathol \| volume = 23 \| issue = 6 \| pages = 844-55 \| month = Jun \| year = 2010 \| doi = 10.1038/modpathol.2010.60 \| PMID = 20228782 }}</ref>
			*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148026/figure/F3/ STIC - schematic (nih.gov)].<ref name=pmid21683865>{{Cite journal \| last1 = Kurman \| first1 = RJ. \| last2 = Shih \| first2 = IeM. \| title = Molecular pathogenesis and extraovarian origin of epithelial ovarian cancer--shifting the paradigm. \| journal = Hum Pathol \| volume = 42 \| issue = 7 \| pages = 918-31 \| month = Jul \| year = 2011 \| doi = 10.1016/j.humpath.2011.03.003 \| PMID = 21683865 }}</ref>
			*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148026/figure/F6/ STIC and STIL with p53 stain (nih.gov)].<ref name=pmid21683865/>
			*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148026/figure/F5/ STIC - p53 stain (nih.gov)].<ref name=pmid21683865/>
			*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860809/figure/fig1/ Small STIC - H&E and p53 (nih.gov)].<ref name=pmid20445756>{{Cite journal \| last1 = Gross \| first1 = AL. \| last2 = Kurman \| first2 = RJ. \| last3 = Vang \| first3 = R. \| last4 = Shih \| first4 = IeM. \| last5 = Visvanathan \| first5 = K. \| title = Precursor lesions of high-grade serous ovarian carcinoma: morphological and molecular characteristics. \| journal = J Oncol \| volume = 2010 \| issue = \| pages = 126295 \| month = \| year = 2010 \| doi = 10.1155/2010/126295 \| PMID = 20445756 }}</ref>
			*[http://www.ovariancancerprevention.org/wp-content/uploads/2010/10/apotosis-and-mitosis-in-STIC.jpg STIC - high mag. (ovariancancerprevention.org)].<ref>URL: [http://www.ovariancancerprevention.org/?page_id=191 http://www.ovariancancerprevention.org/?page_id=191]. Accessed on: 13 May 2014.</ref>
			*[http://www.ovariancancerprevention.org/wp-content/uploads/2010/10/STIC-junction-HM.jpg STIC & benign - high mag. (ovariancancerprevention.org)].

			==IHC==
			Features:<ref name=pmid21989347/>
			*p53 +ve.
			*Ki-67 increased ~10%. (???)
			*p16 +ve.<ref name=pmid20228782/>

			===Images===
			<gallery>
	Image: Serous tubal intraepithelial carcinoma - p16 -- very low mag.jpg \| STIC - p16 - very low mag. (WC)		Image: Serous tubal intraepithelial carcinoma - p16 -- very low mag.jpg \| STIC - p16 - very low mag. (WC)
	Image: Serous tubal intraepithelial carcinoma - p16 -- low mag.jpg \| STIC - p16 - low mag. (WC)		Image: Serous tubal intraepithelial carcinoma - p16 -- low mag.jpg \| STIC - p16 - low mag. (WC)
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	Image: Serous tubal intraepithelial carcinoma - Ki-67 -- high mag.jpg \| STIC - Ki-67 - high mag. (WC)		Image: Serous tubal intraepithelial carcinoma - Ki-67 -- high mag.jpg \| STIC - Ki-67 - high mag. (WC)
	</gallery>		</gallery>
	~~====www====~~
	*[http://www.nature.com/modpathol/journal/v23/n6/fig_tab/modpathol201060f1.html#figure-title STIC (nature.com)].<ref name=pmid20228782>{{Cite journal \| last1 = Sehdev \| first1 = AS. \| last2 = Kurman \| first2 = RJ. \| last3 = Kuhn \| first3 = E. \| last4 = Shih \| first4 = IeM. \| title = Serous tubal intraepithelial carcinoma upregulates markers associated with high-grade serous carcinomas including Rsf-1 (HBXAP), cyclin E and fatty acid synthase. \| journal = Mod Pathol \| volume = 23 \| issue = 6 \| pages = 844-55 \| month = Jun \| year = 2010 \| doi = 10.1038/modpathol.2010.60 \| PMID = 20228782 }}</ref>
	*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148026/figure/F3/ STIC - schematic (nih.gov)].<ref name=pmid21683865>{{Cite journal \| last1 = Kurman \| first1 = RJ. \| last2 = Shih \| first2 = IeM. \| title = Molecular pathogenesis and extraovarian origin of epithelial ovarian cancer--shifting the paradigm. \| journal = Hum Pathol \| volume = 42 \| issue = 7 \| pages = 918-31 \| month = Jul \| year = 2011 \| doi = 10.1016/j.humpath.2011.03.003 \| PMID = 21683865 }}</ref>
	*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148026/figure/F6/ STIC and STIL with p53 stain (nih.gov)].<ref name=pmid21683865/>
	*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148026/figure/F5/ STIC - p53 stain (nih.gov)].<ref name=pmid21683865/>
	*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860809/figure/fig1/ Small STIC - H&E and p53 (nih.gov)].<ref name=pmid20445756>{{Cite journal \| last1 = Gross \| first1 = AL. \| last2 = Kurman \| first2 = RJ. \| last3 = Vang \| first3 = R. \| last4 = Shih \| first4 = IeM. \| last5 = Visvanathan \| first5 = K. \| title = Precursor lesions of high-grade serous ovarian carcinoma: morphological and molecular characteristics. \| journal = J Oncol \| volume = 2010 \| issue = \| pages = 126295 \| month = \| year = 2010 \| doi = 10.1155/2010/126295 \| PMID = 20445756 }}</ref>
	*[http://www.ovariancancerprevention.org/wp-content/uploads/2010/10/apotosis-and-mitosis-in-STIC.jpg STIC - high mag. (ovariancancerprevention.org)].<ref>URL: [http://www.ovariancancerprevention.org/?page_id=191 http://www.ovariancancerprevention.org/?page_id=191]. Accessed on: 13 May 2014.</ref>
	*[http://www.ovariancancerprevention.org/wp-content/uploads/2010/10/STIC-junction-HM.jpg STIC & benign - high mag. (ovariancancerprevention.org)].

	~~==IHC==~~
	~~Features:<ref name=pmid21989347/>~~
	*p53 +ve.
	*Ki-67 increased ~10%. (???)
	*p16 +ve.<ref name=pmid20228782/>

	==See also==		==See also==

Michael at 04:18, 1 January 2020

2020-01-01T04:18:22Z

← Older revision		Revision as of 04:18, 1 January 2020
Line 19:		Line 19:
	\| Assdx =		\| Assdx =
	\| Syndromes =		\| Syndromes =
	\| Clinicalhx = ~~BRCA mutation carrier~~		\| Clinicalhx =
	\| Signs =		\| Signs =
	\| Symptoms = none		\| Symptoms = none

Michael at 04:17, 1 January 2020

2020-01-01T04:17:41Z

← Older revision		Revision as of 04:17, 1 January 2020
Line 19:		Line 19:
	\| Assdx =		\| Assdx =
	\| Syndromes =		\| Syndromes =
	\| Clinicalhx =		\| Clinicalhx = BRCA mutation carrier
	\| Signs =		\| Signs =
	\| Symptoms = none		\| Symptoms = none
Line 29:		Line 29:
	\| Other =		\| Other =
	\| ClinDDx =		\| ClinDDx =
	\| Tx =		\| Tx =
	}}		}}
	'''Serous tubal intraepithelial carcinoma''', abbreviated '''STIC'''<ref name=pmid21989347>{{Cite journal \| last1 = Visvanathan \| first1 = K. \| last2 = Vang \| first2 = R. \| last3 = Shaw \| first3 = P. \| last4 = Gross \| first4 = A. \| last5 = Soslow \| first5 = R. \| last6 = Parkash \| first6 = V. \| last7 = Shih \| first7 = IeM. \| last8 = Kurman \| first8 = RJ. \| title = Diagnosis of serous tubal intraepithelial carcinoma based on morphologic and immunohistochemical features: a reproducibility study. \| journal = Am J Surg Pathol \| volume = 35 \| issue = 12 \| pages = 1766-75 \| month = Dec \| year = 2011 \| doi = 10.1097/PAS.0b013e31822f58bc \| PMID = 21989347 }}</ref> (pronounced ''stick''), is considered to be the precursor of [[serous carcinoma]].		'''Serous tubal intraepithelial carcinoma''', abbreviated '''STIC'''<ref name=pmid21989347>{{Cite journal \| last1 = Visvanathan \| first1 = K. \| last2 = Vang \| first2 = R. \| last3 = Shaw \| first3 = P. \| last4 = Gross \| first4 = A. \| last5 = Soslow \| first5 = R. \| last6 = Parkash \| first6 = V. \| last7 = Shih \| first7 = IeM. \| last8 = Kurman \| first8 = RJ. \| title = Diagnosis of serous tubal intraepithelial carcinoma based on morphologic and immunohistochemical features: a reproducibility study. \| journal = Am J Surg Pathol \| volume = 35 \| issue = 12 \| pages = 1766-75 \| month = Dec \| year = 2011 \| doi = 10.1097/PAS.0b013e31822f58bc \| PMID = 21989347 }}</ref> (pronounced ''stick''), is considered to be the precursor of [[serous carcinoma]].

Michael at 04:16, 1 January 2020

2020-01-01T04:16:03Z

← Older revision		Revision as of 04:16, 1 January 2020
Line 5:		Line 5:
	\| Caption = Micrograph showing serous tubal intraepithelial carcinoma. [[H&E stain]].		\| Caption = Micrograph showing serous tubal intraepithelial carcinoma. [[H&E stain]].
	\| Synonyms =		\| Synonyms =
	\| Micro =		\| Micro = three of the following five: (1) atypical chromatin pattern, (2) nuclear enlargement, (3) nuclear pleomorphism, (4) nuclear moulding, (5) loss of nuclear polarity ''or'' epithelial stratification
	\| Subtypes =		\| Subtypes =
	\| LMDDx =		\| LMDDx =
	\| Stains =		\| Stains =
	\| IHC =		\| IHC = p16 +ve, p53 +ve, Ki-67 increased
	\| EM =		\| EM =
	\| Molecular = BRCA1 mutation or BRCA2 mutation		\| Molecular = BRCA1 mutation or BRCA2 mutation
	\| IF =		\| IF =
	\| Gross =		\| Gross = not apparent on gross
	\| Grossing =		\| Grossing =
	\| Staging =		\| Staging =

Michael: +infobox

2020-01-01T04:13:23Z

+infobox

← Older revision		Revision as of 04:13, 1 January 2020
Line 1:		Line 1:
			{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image = Serous tubal intraepithelial carcinoma -- low mag.jpg
			\| Width =
			\| Caption = Micrograph showing serous tubal intraepithelial carcinoma. [[H&E stain]].
			\| Synonyms =
			\| Micro =
			\| Subtypes =
			\| LMDDx =
			\| Stains =
			\| IHC =
			\| EM =
			\| Molecular = BRCA1 mutation or BRCA2 mutation
			\| IF =
			\| Gross =
			\| Grossing =
			\| Staging =
			\| Site = [[fallopian tubes]]
			\| Assdx =
			\| Syndromes =
			\| Clinicalhx =
			\| Signs =
			\| Symptoms = none
			\| Prevalence = uncommon
			\| Bloodwork =
			\| Rads =
			\| Endoscopy =
			\| Prognosis =
			\| Other =
			\| ClinDDx =
			\| Tx =
			}}
	'''Serous tubal intraepithelial carcinoma''', abbreviated '''STIC'''<ref name=pmid21989347>{{Cite journal \| last1 = Visvanathan \| first1 = K. \| last2 = Vang \| first2 = R. \| last3 = Shaw \| first3 = P. \| last4 = Gross \| first4 = A. \| last5 = Soslow \| first5 = R. \| last6 = Parkash \| first6 = V. \| last7 = Shih \| first7 = IeM. \| last8 = Kurman \| first8 = RJ. \| title = Diagnosis of serous tubal intraepithelial carcinoma based on morphologic and immunohistochemical features: a reproducibility study. \| journal = Am J Surg Pathol \| volume = 35 \| issue = 12 \| pages = 1766-75 \| month = Dec \| year = 2011 \| doi = 10.1097/PAS.0b013e31822f58bc \| PMID = 21989347 }}</ref> (pronounced ''stick''), is considered to be the precursor of [[serous carcinoma]].		'''Serous tubal intraepithelial carcinoma''', abbreviated '''STIC'''<ref name=pmid21989347>{{Cite journal \| last1 = Visvanathan \| first1 = K. \| last2 = Vang \| first2 = R. \| last3 = Shaw \| first3 = P. \| last4 = Gross \| first4 = A. \| last5 = Soslow \| first5 = R. \| last6 = Parkash \| first6 = V. \| last7 = Shih \| first7 = IeM. \| last8 = Kurman \| first8 = RJ. \| title = Diagnosis of serous tubal intraepithelial carcinoma based on morphologic and immunohistochemical features: a reproducibility study. \| journal = Am J Surg Pathol \| volume = 35 \| issue = 12 \| pages = 1766-75 \| month = Dec \| year = 2011 \| doi = 10.1097/PAS.0b013e31822f58bc \| PMID = 21989347 }}</ref> (pronounced ''stick''), is considered to be the precursor of [[serous carcinoma]].

Michael: +images

2020-01-01T04:09:31Z

+images

← Older revision		Revision as of 04:09, 1 January 2020
Line 29:		Line 29:

	===Images===		===Images===
			<gallery>
			Image: Serous tubal intraepithelial carcinoma -- extremely low mag.jpg \| STIC - extremely low mag. (WC)
			Image: Serous tubal intraepithelial carcinoma -- very low mag.jpg \| STIC - very low mag. (WC)
			Image: Serous tubal intraepithelial carcinoma -- low mag.jpg \| STIC - low mag. (WC)
			Image: Serous tubal intraepithelial carcinoma -- intermed mag.jpg \| STIC - intermed. mag. (WC)
			Image: Serous tubal intraepithelial carcinoma - alt -- intermed mag.jpg \| STIC - intermed. mag. (WC)
			Image: Serous tubal intraepithelial carcinoma -- high mag.jpg \| STIC - high mag. (WC)
			Image: Serous tubal intraepithelial carcinoma - alt -- high mag.jpg \| STIC - high mag. (WC)
			Image: Serous tubal intraepithelial carcinoma -- very high mag.jpg \| STIC - very high mag. (WC)

			Image: Serous tubal intraepithelial carcinoma - p16 -- very low mag.jpg \| STIC - p16 - very low mag. (WC)
			Image: Serous tubal intraepithelial carcinoma - p16 -- low mag.jpg \| STIC - p16 - low mag. (WC)
			Image: Serous tubal intraepithelial carcinoma - p16 -- intermed mag.jpg \| STIC - p16 - intermed. mag. (WC)
			Image: Serous tubal intraepithelial carcinoma - p16 -- high mag.jpg \| STIC - p16 - high mag. (WC)

			Image: Serous tubal intraepithelial carcinoma - p53 -- very low mag.jpg \| STIC - p53 - very low mag. (WC)
			Image: Serous tubal intraepithelial carcinoma - p53 -- low mag.jpg \| STIC - p53 - low mag. (WC)
			Image: Serous tubal intraepithelial carcinoma - p53 -- intermed mag.jpg \| STIC - p53 - intermed. mag. (WC)
			Image: Serous tubal intraepithelial carcinoma - p53 -- high mag.jpg \| STIC - p53 - high mag. (WC)

			Image: Serous tubal intraepithelial carcinoma - Ki-67 -- very low mag.jpg \| STIC - Ki-67 - very low mag. (WC)
			Image: Serous tubal intraepithelial carcinoma - Ki-67 -- low mag.jpg \| STIC - Ki-67 - low mag. (WC)
			Image: Serous tubal intraepithelial carcinoma - Ki-67 -- high mag.jpg \| STIC - Ki-67 - high mag. (WC)
			</gallery>
			====www====
	*[http://www.nature.com/modpathol/journal/v23/n6/fig_tab/modpathol201060f1.html#figure-title STIC (nature.com)].<ref name=pmid20228782>{{Cite journal \| last1 = Sehdev \| first1 = AS. \| last2 = Kurman \| first2 = RJ. \| last3 = Kuhn \| first3 = E. \| last4 = Shih \| first4 = IeM. \| title = Serous tubal intraepithelial carcinoma upregulates markers associated with high-grade serous carcinomas including Rsf-1 (HBXAP), cyclin E and fatty acid synthase. \| journal = Mod Pathol \| volume = 23 \| issue = 6 \| pages = 844-55 \| month = Jun \| year = 2010 \| doi = 10.1038/modpathol.2010.60 \| PMID = 20228782 }}</ref>		*[http://www.nature.com/modpathol/journal/v23/n6/fig_tab/modpathol201060f1.html#figure-title STIC (nature.com)].<ref name=pmid20228782>{{Cite journal \| last1 = Sehdev \| first1 = AS. \| last2 = Kurman \| first2 = RJ. \| last3 = Kuhn \| first3 = E. \| last4 = Shih \| first4 = IeM. \| title = Serous tubal intraepithelial carcinoma upregulates markers associated with high-grade serous carcinomas including Rsf-1 (HBXAP), cyclin E and fatty acid synthase. \| journal = Mod Pathol \| volume = 23 \| issue = 6 \| pages = 844-55 \| month = Jun \| year = 2010 \| doi = 10.1038/modpathol.2010.60 \| PMID = 20228782 }}</ref>
	*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148026/figure/F3/ STIC - schematic (nih.gov)].<ref name=pmid21683865>{{Cite journal \| last1 = Kurman \| first1 = RJ. \| last2 = Shih \| first2 = IeM. \| title = Molecular pathogenesis and extraovarian origin of epithelial ovarian cancer--shifting the paradigm. \| journal = Hum Pathol \| volume = 42 \| issue = 7 \| pages = 918-31 \| month = Jul \| year = 2011 \| doi = 10.1016/j.humpath.2011.03.003 \| PMID = 21683865 }}</ref>		*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148026/figure/F3/ STIC - schematic (nih.gov)].<ref name=pmid21683865>{{Cite journal \| last1 = Kurman \| first1 = RJ. \| last2 = Shih \| first2 = IeM. \| title = Molecular pathogenesis and extraovarian origin of epithelial ovarian cancer--shifting the paradigm. \| journal = Hum Pathol \| volume = 42 \| issue = 7 \| pages = 918-31 \| month = Jul \| year = 2011 \| doi = 10.1016/j.humpath.2011.03.003 \| PMID = 21683865 }}</ref>

Michael: /* Microscopic */

2014-07-15T20:02:40Z

Microscopic

← Older revision		Revision as of 20:02, 15 July 2014
Line 21:		Line 21:
	*#Loss of nuclear polarity ''or'' epithelial stratification.		*#Loss of nuclear polarity ''or'' epithelial stratification.

	~~Note~~:		Notes:
	*At low power STIC is usually tall cells that are too blue.		*At low power STIC is usually tall cells that are too blue.
	*Cilia suggest benign.		*Cilia suggest benign.

Michael at 20:00, 15 July 2014

2014-07-15T20:00:29Z

← Older revision		Revision as of 20:00, 15 July 2014
Line 26:		Line 26:

	DDx:		DDx:
	*STIL - lack proliferation.{{fact}}		*Atypical tubal lesion (STIL or TILT) - lack proliferation.{{fact}}

	===Images===		===Images===

← Older revision		Revision as of 04:09, 1 January 2020
Line 29:		Line 29:

	===Images===		===Images===
			<gallery>
			Image: Serous tubal intraepithelial carcinoma -- extremely low mag.jpg \| STIC - extremely low mag. (WC)
			Image: Serous tubal intraepithelial carcinoma -- very low mag.jpg \| STIC - very low mag. (WC)
			Image: Serous tubal intraepithelial carcinoma -- low mag.jpg \| STIC - low mag. (WC)
			Image: Serous tubal intraepithelial carcinoma -- intermed mag.jpg \| STIC - intermed. mag. (WC)
			Image: Serous tubal intraepithelial carcinoma - alt -- intermed mag.jpg \| STIC - intermed. mag. (WC)
			Image: Serous tubal intraepithelial carcinoma -- high mag.jpg \| STIC - high mag. (WC)
			Image: Serous tubal intraepithelial carcinoma - alt -- high mag.jpg \| STIC - high mag. (WC)
			Image: Serous tubal intraepithelial carcinoma -- very high mag.jpg \| STIC - very high mag. (WC)

			Image: Serous tubal intraepithelial carcinoma - p16 -- very low mag.jpg \| STIC - p16 - very low mag. (WC)
			Image: Serous tubal intraepithelial carcinoma - p16 -- low mag.jpg \| STIC - p16 - low mag. (WC)
			Image: Serous tubal intraepithelial carcinoma - p16 -- intermed mag.jpg \| STIC - p16 - intermed. mag. (WC)
			Image: Serous tubal intraepithelial carcinoma - p16 -- high mag.jpg \| STIC - p16 - high mag. (WC)

			Image: Serous tubal intraepithelial carcinoma - p53 -- very low mag.jpg \| STIC - p53 - very low mag. (WC)
			Image: Serous tubal intraepithelial carcinoma - p53 -- low mag.jpg \| STIC - p53 - low mag. (WC)
			Image: Serous tubal intraepithelial carcinoma - p53 -- intermed mag.jpg \| STIC - p53 - intermed. mag. (WC)
			Image: Serous tubal intraepithelial carcinoma - p53 -- high mag.jpg \| STIC - p53 - high mag. (WC)

			Image: Serous tubal intraepithelial carcinoma - Ki-67 -- very low mag.jpg \| STIC - Ki-67 - very low mag. (WC)
			Image: Serous tubal intraepithelial carcinoma - Ki-67 -- low mag.jpg \| STIC - Ki-67 - low mag. (WC)
			Image: Serous tubal intraepithelial carcinoma - Ki-67 -- high mag.jpg \| STIC - Ki-67 - high mag. (WC)
			</gallery>
			====www====
	*[http://www.nature.com/modpathol/journal/v23/n6/fig_tab/modpathol201060f1.html#figure-title STIC (nature.com)].<ref name=pmid20228782>{{Cite journal \| last1 = Sehdev \| first1 = AS. \| last2 = Kurman \| first2 = RJ. \| last3 = Kuhn \| first3 = E. \| last4 = Shih \| first4 = IeM. \| title = Serous tubal intraepithelial carcinoma upregulates markers associated with high-grade serous carcinomas including Rsf-1 (HBXAP), cyclin E and fatty acid synthase. \| journal = Mod Pathol \| volume = 23 \| issue = 6 \| pages = 844-55 \| month = Jun \| year = 2010 \| doi = 10.1038/modpathol.2010.60 \| PMID = 20228782 }}</ref>		*[http://www.nature.com/modpathol/journal/v23/n6/fig_tab/modpathol201060f1.html#figure-title STIC (nature.com)].<ref name=pmid20228782>{{Cite journal \| last1 = Sehdev \| first1 = AS. \| last2 = Kurman \| first2 = RJ. \| last3 = Kuhn \| first3 = E. \| last4 = Shih \| first4 = IeM. \| title = Serous tubal intraepithelial carcinoma upregulates markers associated with high-grade serous carcinomas including Rsf-1 (HBXAP), cyclin E and fatty acid synthase. \| journal = Mod Pathol \| volume = 23 \| issue = 6 \| pages = 844-55 \| month = Jun \| year = 2010 \| doi = 10.1038/modpathol.2010.60 \| PMID = 20228782 }}</ref>
	*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148026/figure/F3/ STIC - schematic (nih.gov)].<ref name=pmid21683865>{{Cite journal \| last1 = Kurman \| first1 = RJ. \| last2 = Shih \| first2 = IeM. \| title = Molecular pathogenesis and extraovarian origin of epithelial ovarian cancer--shifting the paradigm. \| journal = Hum Pathol \| volume = 42 \| issue = 7 \| pages = 918-31 \| month = Jul \| year = 2011 \| doi = 10.1016/j.humpath.2011.03.003 \| PMID = 21683865 }}</ref>		*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148026/figure/F3/ STIC - schematic (nih.gov)].<ref name=pmid21683865>{{Cite journal \| last1 = Kurman \| first1 = RJ. \| last2 = Shih \| first2 = IeM. \| title = Molecular pathogenesis and extraovarian origin of epithelial ovarian cancer--shifting the paradigm. \| journal = Hum Pathol \| volume = 42 \| issue = 7 \| pages = 918-31 \| month = Jul \| year = 2011 \| doi = 10.1016/j.humpath.2011.03.003 \| PMID = 21683865 }}</ref>