Small cell carcinoma - Revision history

Michael: /* Microscopic */

2016-04-26T13:12:46Z

Microscopic

← Older revision		Revision as of 13:12, 26 April 2016
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	*[[Chloroma]].		*[[Chloroma]].
	*[[Rhabdomyosarcoma]] - usu. [[CD56]] positive, may be keratin positive and positive for other [[neuroendocrine markers]].<ref name=pmid18487991>{{Cite journal \| last1 = Bahrami \| first1 = A. \| last2 = Gown \| first2 = AM. \| last3 = Baird \| first3 = GS. \| last4 = Hicks \| first4 = MJ. \| last5 = Folpe \| first5 = AL. \| title = Aberrant expression of epithelial and neuroendocrine markers in alveolar rhabdomyosarcoma: a potentially serious diagnostic pitfall. \| journal = Mod Pathol \| volume = 21 \| issue = 7 \| pages = 795-806 \| month = Jul \| year = 2008 \| doi = 10.1038/modpathol.2008.86 \| PMID = 18487991 }}</ref>		*[[Rhabdomyosarcoma]] - usu. [[CD56]] positive, may be keratin positive and positive for other [[neuroendocrine markers]].<ref name=pmid18487991>{{Cite journal \| last1 = Bahrami \| first1 = A. \| last2 = Gown \| first2 = AM. \| last3 = Baird \| first3 = GS. \| last4 = Hicks \| first4 = MJ. \| last5 = Folpe \| first5 = AL. \| title = Aberrant expression of epithelial and neuroendocrine markers in alveolar rhabdomyosarcoma: a potentially serious diagnostic pitfall. \| journal = Mod Pathol \| volume = 21 \| issue = 7 \| pages = 795-806 \| month = Jul \| year = 2008 \| doi = 10.1038/modpathol.2008.86 \| PMID = 18487991 }}</ref>
			*[[Atypical lung carcinoid tumour]] (lung only).
			*[[Typical lung carcinoid tumour]] (lung only).
	*Other [[small round cell tumours]].		*Other [[small round cell tumours]].

Michael: /* Cytology */

2016-04-24T04:26:55Z

Cytology

← Older revision		Revision as of 04:26, 24 April 2016
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	<gallery>		<gallery>
	Image:Small_cell_lung_cancer_-_cytology.jpg \| Small cell carcinoma - cytology - Field stain. (WC)		Image:Small_cell_lung_cancer_-_cytology.jpg \| Small cell carcinoma - cytology - Field stain. (WC)
	Image: Lung small cell carcinoma - Diff-Quik -- high mag.jpg \| SmCC - Diff-Quik - high mag.		Image: Lung small cell carcinoma - Diff-Quik -- high mag.jpg \| SmCC - Diff-Quik - high mag. (WC)
	Image: Lung small cell carcinoma - Diff-Quik -- very high mag.jpg \| SmCC - Diff-Quik - very high mag.		Image: Lung small cell carcinoma - Diff-Quik -- very high mag.jpg \| SmCC - Diff-Quik - very high mag. (WC)
	Image: Lung small cell carcinoma - Diff-Quik -- extremely high mag.jpg \| SmCC - Diff-Quik - extremely high mag.		Image: Lung small cell carcinoma - Diff-Quik -- extremely high mag.jpg \| SmCC - Diff-Quik - extremely high mag. (WC)
	Image: Lung small cell carcinoma -- very high mag.jpg \| SmCC - Pap stain - very high mag.		Image: Lung small cell carcinoma -- very high mag.jpg \| SmCC - Pap stain - very high mag. (WC)
	Image: Lung small cell carcinoma -- extremely high mag.jpg \| SmCC - Pap stain - extremely high mag.		Image: Lung small cell carcinoma -- extremely high mag.jpg \| SmCC - Pap stain - extremely high mag. (WC)
	</gallery>		</gallery>

Michael: /* Cytology */

2016-04-24T04:26:30Z

Cytology

← Older revision		Revision as of 04:26, 24 April 2016
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	<gallery>		<gallery>
	Image:Small_cell_lung_cancer_-_cytology.jpg \| Small cell carcinoma - cytology - Field stain. (WC)		Image:Small_cell_lung_cancer_-_cytology.jpg \| Small cell carcinoma - cytology - Field stain. (WC)
	Image: Lung small cell carcinoma - Diff-Quik -- high mag.jpg \| SmCC - DQ - high mag.		Image: Lung small cell carcinoma - Diff-Quik -- high mag.jpg \| SmCC - Diff-Quik - high mag.
	Image: Lung small cell carcinoma - Diff-Quik -- very high mag.jpg \| SmCC - DQ - very high mag.		Image: Lung small cell carcinoma - Diff-Quik -- very high mag.jpg \| SmCC - Diff-Quik - very high mag.
	Image: Lung small cell carcinoma - Diff-Quik -- extremely high mag.jpg \| SmCC - DQ - extremely high mag.		Image: Lung small cell carcinoma - Diff-Quik -- extremely high mag.jpg \| SmCC - Diff-Quik - extremely high mag.
	Image: Lung small cell carcinoma -- very high mag.jpg \| SmCC - DQ - very high mag.		Image: Lung small cell carcinoma -- very high mag.jpg \| SmCC - Pap stain - very high mag.
	Image: Lung small cell carcinoma -- extremely high mag.jpg \| SmCC - DQ - extremely high mag.		Image: Lung small cell carcinoma -- extremely high mag.jpg \| SmCC - Pap stain - extremely high mag.
	</gallery>		</gallery>

	====Metastatic====		====Metastatic====
	<gallery>		<gallery>

Michael: /* Images */

2016-04-24T04:22:43Z

Images

← Older revision		Revision as of 04:22, 24 April 2016
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	===Images===		===Images===
			====Cytology====
			<gallery>
			Image:Small_cell_lung_cancer_-_cytology.jpg \| Small cell carcinoma - cytology - Field stain. (WC)
			Image: Lung small cell carcinoma - Diff-Quik -- high mag.jpg \| SmCC - DQ - high mag.
			Image: Lung small cell carcinoma - Diff-Quik -- very high mag.jpg \| SmCC - DQ - very high mag.
			Image: Lung small cell carcinoma - Diff-Quik -- extremely high mag.jpg \| SmCC - DQ - extremely high mag.
			Image: Lung small cell carcinoma -- very high mag.jpg \| SmCC - DQ - very high mag.
			Image: Lung small cell carcinoma -- extremely high mag.jpg \| SmCC - DQ - extremely high mag.
			</gallery>
			====Metastatic====
	<gallery>		<gallery>
	~~Image:Small_cell_lung_cancer_-_cytology.jpg \| Small cell carcinoma - cytology (WC)~~
	Image:Metastatic_small_cell_carcinoma_-_high_mag.jpg \| Metastatic small cell carcinoma - high mag. (WC)		Image:Metastatic_small_cell_carcinoma_-_high_mag.jpg \| Metastatic small cell carcinoma - high mag. (WC)
	Image:Metastatic_small_cell_carcinoma_-_very_high_mag.jpg \| Metastatic small cell carcinoma - very high mag. (WC)		Image:Metastatic_small_cell_carcinoma_-_very_high_mag.jpg \| Metastatic small cell carcinoma - very high mag. (WC)

Michael: /* Sites other than lung */

2016-01-29T17:41:48Z

Sites other than lung

← Older revision		Revision as of 17:41, 29 January 2016
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	*Breast.<ref name=pmid21657157>{{Cite journal \| last1 = Cesaretti \| first1 = M. \| last2 = Guarnieri \| first2 = A. \| last3 = Gaggelli \| first3 = I. \| last4 = Tirone \| first4 = A. \| last5 = Francioli \| first5 = N. \| last6 = Carli \| first6 = AF. \| title = Small cell carcinoma of the breast. Report of a case. \| journal = Ann Ital Chir \| volume = 82 \| issue = 1 \| pages = 61-4 \| month = \| year = \| doi = \| PMID = 21657157 }}</ref>		*Breast.<ref name=pmid21657157>{{Cite journal \| last1 = Cesaretti \| first1 = M. \| last2 = Guarnieri \| first2 = A. \| last3 = Gaggelli \| first3 = I. \| last4 = Tirone \| first4 = A. \| last5 = Francioli \| first5 = N. \| last6 = Carli \| first6 = AF. \| title = Small cell carcinoma of the breast. Report of a case. \| journal = Ann Ital Chir \| volume = 82 \| issue = 1 \| pages = 61-4 \| month = \| year = \| doi = \| PMID = 21657157 }}</ref>
	*Thyroid gland.<ref name=pmid21644012>{{Cite journal \| last1 = Beach \| first1 = DF. \| last2 = Klump \| first2 = WJ. \| last3 = Haddad \| first3 = G. \| last4 = Reid \| first4 = LM. \| last5 = Schwarting \| first5 = R. \| last6 = Hageboutros \| first6 = A. \| title = Extrapulmonary small cell: a novel case of small cell carcinoma of the thyroid gland. \| journal = Med Oncol \| volume = \| issue = \| pages = \| month = Jun \| year = 2011 \| doi = 10.1007/s12032-011-9996-7 \| PMID = 21644012 }}</ref>		*Thyroid gland.<ref name=pmid21644012>{{Cite journal \| last1 = Beach \| first1 = DF. \| last2 = Klump \| first2 = WJ. \| last3 = Haddad \| first3 = G. \| last4 = Reid \| first4 = LM. \| last5 = Schwarting \| first5 = R. \| last6 = Hageboutros \| first6 = A. \| title = Extrapulmonary small cell: a novel case of small cell carcinoma of the thyroid gland. \| journal = Med Oncol \| volume = \| issue = \| pages = \| month = Jun \| year = 2011 \| doi = 10.1007/s12032-011-9996-7 \| PMID = 21644012 }}</ref>
	*Liver.<ref name=pmid19669327>{{Cite journal \| last1 = Morikawa \| first1 = H. \| last2 = Nakayama \| first2 = Y. \| last3 = Maeda \| first3 = T. \| last4 = Nadatani \| first4 = Y. \| last5 = Kobayashi \| first5 = S. \| last6 = Iwai \| first6 = S. \| last7 = Enomoto \| first7 = M. \| last8 = Tamori \| first8 = A. \| last9 = Sakaguchi \| first9 = H. \| title = A case of primary small cell carcinoma of the liver that was treated with chemotherapy. \| journal = Hepatol Int \| volume = 2 \| issue = 4 \| pages = 500-4 \| month = Dec \| year = 2008 \| doi = 10.1007/s12072-008-9090-1 \| PMID = 19669327 }}</ref>		*Liver.<ref name=pmid19669327>{{Cite journal \| last1 = Morikawa \| first1 = H. \| last2 = Nakayama \| first2 = Y. \| last3 = Maeda \| first3 = T. \| last4 = Nadatani \| first4 = Y. \| last5 = Kobayashi \| first5 = S. \| last6 = Iwai \| first6 = S. \| last7 = Enomoto \| first7 = M. \| last8 = Tamori \| first8 = A. \| last9 = Sakaguchi \| first9 = H. \| title = A case of primary small cell carcinoma of the liver that was treated with chemotherapy. \| journal = Hepatol Int \| volume = 2 \| issue = 4 \| pages = 500-4 \| month = Dec \| year = 2008 \| doi = 10.1007/s12072-008-9090-1 \| PMID = 19669327 }}</ref><ref name=pmid18159605>{{Cite journal \| last1 = Choi \| first1 = SJ. \| last2 = Kim \| first2 = JM. \| last3 = Han \| first3 = JY. \| last4 = Ahn \| first4 = SI. \| last5 = Kim \| first5 = JS. \| last6 = Kim \| first6 = L. \| last7 = Park \| first7 = IS. \| last8 = Chu \| first8 = YC. \| title = Extrapulmonary small cell carcinoma of the liver: clinicopathological and immunohistochemical findings. \| journal = Yonsei Med J \| volume = 48 \| issue = 6 \| pages = 1066-71 \| month = Dec \| year = 2007 \| doi = 10.3349/ymj.2007.48.6.1066 \| PMID = 18159605 }}</ref>

	==General==		==General==

Michael: /* IHC */

2016-01-29T17:32:25Z

IHC

← Older revision		Revision as of 17:32, 29 January 2016
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	==IHC==		==IHC==
	*[[Neuroendocrine markers]] +ve - confirm the diagnosis.		*[[Neuroendocrine markers]] +ve - confirm the diagnosis.
	*~~Not~~ particularity useful for determination of the primary site.<ref name=pmid17270664>{{Cite journal \| last1 = Lobins \| first1 = R. \| last2 = Floyd \| first2 = J. \| title = Small cell carcinoma of unknown primary. \| journal = Semin Oncol \| volume = 34 \| issue = 1 \| pages = 39-42 \| month = Feb \| year = 2007 \| doi = 10.1053/j.seminoncol.2006.10.027 \| PMID = 17270664 }}</ref> ‡		*IHC not particularity useful for determination of the primary site.<ref name=pmid17270664>{{Cite journal \| last1 = Lobins \| first1 = R. \| last2 = Floyd \| first2 = J. \| title = Small cell carcinoma of unknown primary. \| journal = Semin Oncol \| volume = 34 \| issue = 1 \| pages = 39-42 \| month = Feb \| year = 2007 \| doi = 10.1053/j.seminoncol.2006.10.027 \| PMID = 17270664 }}</ref> ‡

	Note:		Note:

Michael: /* IHC */

2016-01-29T17:32:10Z

IHC

← Older revision		Revision as of 17:32, 29 January 2016
Line 59:		Line 59:

	==IHC==		==IHC==
	*[[Neuroendocrine markers]] +ve - confirm the diagnosis.		*[[Neuroendocrine markers]] +ve - confirm the diagnosis.
	*Not particularity useful for determination of the primary site.<ref name=pmid17270664>{{Cite journal \| last1 = Lobins \| first1 = R. \| last2 = Floyd \| first2 = J. \| title = Small cell carcinoma of unknown primary. \| journal = Semin Oncol \| volume = 34 \| issue = 1 \| pages = 39-42 \| month = Feb \| year = 2007 \| doi = 10.1053/j.seminoncol.2006.10.027 \| PMID = 17270664 }}</ref>		*Not particularity useful for determination of the primary site.<ref name=pmid17270664>{{Cite journal \| last1 = Lobins \| first1 = R. \| last2 = Floyd \| first2 = J. \| title = Small cell carcinoma of unknown primary. \| journal = Semin Oncol \| volume = 34 \| issue = 1 \| pages = 39-42 \| month = Feb \| year = 2007 \| doi = 10.1053/j.seminoncol.2006.10.027 \| PMID = 17270664 }}</ref> ‡

			Note:
			*‡ A CT chest should be done to assess for a lung tumour; fortunately, lung small cell carcinoma and extrapulmonary small cell cancer are treated similarily.<ref name=pmid20052730>{{Cite journal \| last1 = Brennan \| first1 = SM. \| last2 = Gregory \| first2 = DL. \| last3 = Stillie \| first3 = A. \| last4 = Herschtal \| first4 = A. \| last5 = Mac Manus \| first5 = M. \| last6 = Ball \| first6 = DL. \| title = Should extrapulmonary small cell cancer be managed like small cell lung cancer? \| journal = Cancer \| volume = 116 \| issue = 4 \| pages = 888-95 \| month = Feb \| year = 2010 \| doi = 10.1002/cncr.24858 \| PMID = 20052730 }}</ref>

	==See also==		==See also==

Michael at 17:24, 29 January 2016

2016-01-29T17:24:30Z

← Older revision		Revision as of 17:24, 29 January 2016
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	Image: Small cell carcinoma in lymph node -- very high mag.jpg \| Small cell carcinoma in a lymph node - very high mag. (WC)		Image: Small cell carcinoma in lymph node -- very high mag.jpg \| Small cell carcinoma in a lymph node - very high mag. (WC)
	</gallery>		</gallery>

			==IHC==
			*[[Neuroendocrine markers]] +ve - confirm the diagnosis.
			*Not particularity useful for determination of the primary site.<ref name=pmid17270664>{{Cite journal \| last1 = Lobins \| first1 = R. \| last2 = Floyd \| first2 = J. \| title = Small cell carcinoma of unknown primary. \| journal = Semin Oncol \| volume = 34 \| issue = 1 \| pages = 39-42 \| month = Feb \| year = 2007 \| doi = 10.1053/j.seminoncol.2006.10.027 \| PMID = 17270664 }}</ref>

	==See also==		==See also==

Michael: /* Sites other than lung */

2016-01-29T17:22:46Z

Sites other than lung

← Older revision		Revision as of 17:22, 29 January 2016
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	*Breast.<ref name=pmid21657157>{{Cite journal \| last1 = Cesaretti \| first1 = M. \| last2 = Guarnieri \| first2 = A. \| last3 = Gaggelli \| first3 = I. \| last4 = Tirone \| first4 = A. \| last5 = Francioli \| first5 = N. \| last6 = Carli \| first6 = AF. \| title = Small cell carcinoma of the breast. Report of a case. \| journal = Ann Ital Chir \| volume = 82 \| issue = 1 \| pages = 61-4 \| month = \| year = \| doi = \| PMID = 21657157 }}</ref>		*Breast.<ref name=pmid21657157>{{Cite journal \| last1 = Cesaretti \| first1 = M. \| last2 = Guarnieri \| first2 = A. \| last3 = Gaggelli \| first3 = I. \| last4 = Tirone \| first4 = A. \| last5 = Francioli \| first5 = N. \| last6 = Carli \| first6 = AF. \| title = Small cell carcinoma of the breast. Report of a case. \| journal = Ann Ital Chir \| volume = 82 \| issue = 1 \| pages = 61-4 \| month = \| year = \| doi = \| PMID = 21657157 }}</ref>
	*Thyroid gland.<ref name=pmid21644012>{{Cite journal \| last1 = Beach \| first1 = DF. \| last2 = Klump \| first2 = WJ. \| last3 = Haddad \| first3 = G. \| last4 = Reid \| first4 = LM. \| last5 = Schwarting \| first5 = R. \| last6 = Hageboutros \| first6 = A. \| title = Extrapulmonary small cell: a novel case of small cell carcinoma of the thyroid gland. \| journal = Med Oncol \| volume = \| issue = \| pages = \| month = Jun \| year = 2011 \| doi = 10.1007/s12032-011-9996-7 \| PMID = 21644012 }}</ref>		*Thyroid gland.<ref name=pmid21644012>{{Cite journal \| last1 = Beach \| first1 = DF. \| last2 = Klump \| first2 = WJ. \| last3 = Haddad \| first3 = G. \| last4 = Reid \| first4 = LM. \| last5 = Schwarting \| first5 = R. \| last6 = Hageboutros \| first6 = A. \| title = Extrapulmonary small cell: a novel case of small cell carcinoma of the thyroid gland. \| journal = Med Oncol \| volume = \| issue = \| pages = \| month = Jun \| year = 2011 \| doi = 10.1007/s12032-011-9996-7 \| PMID = 21644012 }}</ref>
			*Liver.<ref name=pmid19669327>{{Cite journal \| last1 = Morikawa \| first1 = H. \| last2 = Nakayama \| first2 = Y. \| last3 = Maeda \| first3 = T. \| last4 = Nadatani \| first4 = Y. \| last5 = Kobayashi \| first5 = S. \| last6 = Iwai \| first6 = S. \| last7 = Enomoto \| first7 = M. \| last8 = Tamori \| first8 = A. \| last9 = Sakaguchi \| first9 = H. \| title = A case of primary small cell carcinoma of the liver that was treated with chemotherapy. \| journal = Hepatol Int \| volume = 2 \| issue = 4 \| pages = 500-4 \| month = Dec \| year = 2008 \| doi = 10.1007/s12072-008-9090-1 \| PMID = 19669327 }}</ref>

	==General==		==General==

Michael: /* Images */

2015-01-27T17:48:36Z

Images

← Older revision		Revision as of 17:48, 27 January 2015
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	Image:Metastatic_small_cell_carcinoma_-_very_high_mag.jpg \| Metastatic small cell carcinoma - very high mag. (WC)		Image:Metastatic_small_cell_carcinoma_-_very_high_mag.jpg \| Metastatic small cell carcinoma - very high mag. (WC)
	</gallery>		</gallery>
			====Small cell carcinoma in a lymph node====
	<gallery>		<gallery>
	Image: Small cell carcinoma in lymph node -- low mag.jpg \| Small cell carcinoma in a lymph node - low mag. (WC)		Image: Small cell carcinoma in lymph node -- low mag.jpg \| Small cell carcinoma in a lymph node - low mag. (WC)
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	Image: Small cell carcinoma in lymph node -- very high mag.jpg \| Small cell carcinoma in a lymph node - very high mag. (WC)		Image: Small cell carcinoma in lymph node -- very high mag.jpg \| Small cell carcinoma in a lymph node - very high mag. (WC)
	</gallery>		</gallery>
	~~www:~~
	*[http://networks.lww.com/pathology/blog/iow/pages/post.aspx?PostID=55 Small cell carcinoma in a lymph node (lww.com)].

	==See also==		==See also==

← Older revision		Revision as of 04:26, 24 April 2016
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	<gallery>		<gallery>
	Image:Small_cell_lung_cancer_-_cytology.jpg \| Small cell carcinoma - cytology - Field stain. (WC)		Image:Small_cell_lung_cancer_-_cytology.jpg \| Small cell carcinoma - cytology - Field stain. (WC)
	Image: Lung small cell carcinoma - Diff-Quik -- high mag.jpg \| SmCC - Diff-Quik - high mag.		Image: Lung small cell carcinoma - Diff-Quik -- high mag.jpg \| SmCC - Diff-Quik - high mag. (WC)
	Image: Lung small cell carcinoma - Diff-Quik -- very high mag.jpg \| SmCC - Diff-Quik - very high mag.		Image: Lung small cell carcinoma - Diff-Quik -- very high mag.jpg \| SmCC - Diff-Quik - very high mag. (WC)
	Image: Lung small cell carcinoma - Diff-Quik -- extremely high mag.jpg \| SmCC - Diff-Quik - extremely high mag.		Image: Lung small cell carcinoma - Diff-Quik -- extremely high mag.jpg \| SmCC - Diff-Quik - extremely high mag. (WC)
	Image: Lung small cell carcinoma -- very high mag.jpg \| SmCC - Pap stain - very high mag.		Image: Lung small cell carcinoma -- very high mag.jpg \| SmCC - Pap stain - very high mag. (WC)
	Image: Lung small cell carcinoma -- extremely high mag.jpg \| SmCC - Pap stain - extremely high mag.		Image: Lung small cell carcinoma -- extremely high mag.jpg \| SmCC - Pap stain - extremely high mag. (WC)
	</gallery>		</gallery>