Small cell carcinoma of the prostate gland - Revision history

Michael at 16:33, 19 March 2018

2018-03-19T16:33:19Z

← Older revision		Revision as of 16:33, 19 March 2018
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	'''Small cell carcinoma of the prostate gland''' is a rare type of [[prostate cancer]] with an aggressive course.		'''Small cell carcinoma of the prostate gland''' is a rare type of [[prostate cancer]] with an aggressive course.

	''~~Neuroendocrine carcinoma of the~~ prostate'' redirects to here.<ref name=pmid19092321>{{Cite journal \| last1 = Stein \| first1 = ME. \| last2 = Bernstein \| first2 = Z. \| last3 = Abacioglu \| first3 = U. \| last4 = Sengoz \| first4 = M. \| last5 = Miller \| first5 = RC. \| last6 = Meirovitz \| first6 = A. \| last7 = Zouhair \| first7 = A. \| last8 = Freixa \| first8 = SV. \| last9 = Poortmans \| first9 = PH. \| title = Small cell (neuroendocrine) carcinoma of the prostate: etiology, diagnosis, prognosis, and therapeutic implications--a retrospective study of 30 patients from the rare cancer network. \| journal = Am J Med Sci \| volume = 336 \| issue = 6 \| pages = 478-88 \| month = Dec \| year = 2008 \| doi = 10.1097/MAJ.0b013e3181731e58 \| PMID = 19092321 }}</ref><ref>{{Cite journal \| last1 = Alanee \| first1 = S. \| last2 = Moore \| first2 = A. \| last3 = Nutt \| first3 = M. \| last4 = Holland \| first4 = B. \| last5 = Dynda \| first5 = D. \| last6 = El-Zawahry \| first6 = A. \| last7 = McVary \| first7 = KT. \| title = Contemporary Incidence and Mortality Rates of Neuroendocrine Prostate Cancer. ~~\| journal = Anticancer Res \| volume = 35 \| issue = 7 \| pages = 4145-50 \| month = Jul \| year = 2015 \| doi = \| PMID = 26124369 }}</ref>~~		The more general topic of ''[[prostate cancer with neuroendocrine differentiation]]'' is dealt with in a separate article.

	==General==		==General==

Michael: /* Microscopic */ more

2018-03-19T16:08:44Z

Microscopic: more

← Older revision		Revision as of 16:08, 19 March 2018
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	*[[Small cell carcinoma of the urinary bladder]].		*[[Small cell carcinoma of the urinary bladder]].
	*[[Lymphoma]], large cell.		*[[Lymphoma]], large cell.
			*[[Prostate carcinoma with amphicrine features]] - also have [[AR]] staining.<ref name=pmid28756619>{{Cite journal \| last1 = Prendeville \| first1 = S. \| last2 = Al-Bozom \| first2 = I. \| last3 = Compérat \| first3 = E. \| last4 = Sweet \| first4 = J. \| last5 = Evans \| first5 = AJ. \| last6 = Ben-Gashir \| first6 = M. \| last7 = Mete \| first7 = O. \| last8 = van der Kwast \| first8 = TH. \| last9 = Downes \| first9 = MR. \| title = Prostate carcinoma with amphicrine features: further refining the spectrum of neuroendocrine differentiation in tumours of primary prostatic origin? \| journal = Histopathology \| volume = 71 \| issue = 6 \| pages = 926-933 \| month = Dec \| year = 2017 \| doi = 10.1111/his.13330 \| PMID = 28756619 }}</ref>
	*Other [[small round cell tumours]].		*Other [[small round cell tumours]].

Michael: /* See also */

2016-12-08T12:37:09Z

Michael at 03:41, 9 February 2016

2016-02-09T03:41:18Z

← Older revision		Revision as of 03:41, 9 February 2016
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	\| Gross =		\| Gross =
	\| Grossing = [[prostate biopsy]], [[prostate chips]], [[radical prostatectomy]]		\| Grossing = [[prostate biopsy]], [[prostate chips]], [[radical prostatectomy]]
	\| Staging =		\| Staging = [[prostate cancer staging]]
	\| Site = [[prostate gland]] - see ''[[prostate cancer]]''		\| Site = [[prostate gland]] - see ''[[prostate cancer]]''
	\| Assdx =		\| Assdx =

Michael at 05:01, 24 January 2016

2016-01-24T05:01:59Z

← Older revision		Revision as of 05:01, 24 January 2016
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	\| Symptoms =		\| Symptoms =
	\| Prevalence = rare		\| Prevalence = rare
	\| Bloodwork =		\| Bloodwork = [[PSA]] low (in relation to conventional cancer)
	\| Rads =		\| Rads =
	\| Endoscopy =		\| Endoscopy =

Michael: /* General */

2016-01-24T04:57:09Z

General

← Older revision		Revision as of 04:57, 24 January 2016
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	*Poor prognosis.		*Poor prognosis.
	*Not [[prostate cancer grading\|graded]] ([[ISUP]] 2005 consensus on [[Gleason grading system]]<ref name=pmid16096414>{{Cite journal \| last1 = Epstein \| first1 = JI. \| last2 = Allsbrook \| first2 = WC. \| last3 = Amin \| first3 = MB. \| last4 = Egevad \| first4 = LL. \| title = The 2005 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason Grading of Prostatic Carcinoma. \| journal = Am J Surg Pathol \| volume = 29 \| issue = 9 \| pages = 1228-42 \| month = Sep \| year = 2005 \| doi = \| PMID = 16096414 }}</ref>).		*Not [[prostate cancer grading\|graded]] ([[ISUP]] 2005 consensus on [[Gleason grading system]]<ref name=pmid16096414>{{Cite journal \| last1 = Epstein \| first1 = JI. \| last2 = Allsbrook \| first2 = WC. \| last3 = Amin \| first3 = MB. \| last4 = Egevad \| first4 = LL. \| title = The 2005 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason Grading of Prostatic Carcinoma. \| journal = Am J Surg Pathol \| volume = 29 \| issue = 9 \| pages = 1228-42 \| month = Sep \| year = 2005 \| doi = \| PMID = 16096414 }}</ref>).

			Clinical:
			*PSA often low in comparison to conventional prostate cancer.<ref name=pmid22110988/>

	==Microscopic==		==Microscopic==

Michael at 04:54, 24 January 2016

2016-01-24T04:54:03Z

← Older revision		Revision as of 04:54, 24 January 2016
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	}}		}}
	'''Small cell carcinoma of the prostate gland''' is a rare type of [[prostate cancer]] with an aggressive course.		'''Small cell carcinoma of the prostate gland''' is a rare type of [[prostate cancer]] with an aggressive course.

			''Neuroendocrine carcinoma of the prostate'' redirects to here.<ref name=pmid19092321>{{Cite journal \| last1 = Stein \| first1 = ME. \| last2 = Bernstein \| first2 = Z. \| last3 = Abacioglu \| first3 = U. \| last4 = Sengoz \| first4 = M. \| last5 = Miller \| first5 = RC. \| last6 = Meirovitz \| first6 = A. \| last7 = Zouhair \| first7 = A. \| last8 = Freixa \| first8 = SV. \| last9 = Poortmans \| first9 = PH. \| title = Small cell (neuroendocrine) carcinoma of the prostate: etiology, diagnosis, prognosis, and therapeutic implications--a retrospective study of 30 patients from the rare cancer network. \| journal = Am J Med Sci \| volume = 336 \| issue = 6 \| pages = 478-88 \| month = Dec \| year = 2008 \| doi = 10.1097/MAJ.0b013e3181731e58 \| PMID = 19092321 }}</ref><ref>{{Cite journal \| last1 = Alanee \| first1 = S. \| last2 = Moore \| first2 = A. \| last3 = Nutt \| first3 = M. \| last4 = Holland \| first4 = B. \| last5 = Dynda \| first5 = D. \| last6 = El-Zawahry \| first6 = A. \| last7 = McVary \| first7 = KT. \| title = Contemporary Incidence and Mortality Rates of Neuroendocrine Prostate Cancer. \| journal = Anticancer Res \| volume = 35 \| issue = 7 \| pages = 4145-50 \| month = Jul \| year = 2015 \| doi = \| PMID = 26124369 }}</ref>

	==General==		==General==

Michael at 04:45, 24 January 2016

2016-01-24T04:45:11Z

← Older revision		Revision as of 04:45, 24 January 2016
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	{{ Infobox diagnosis		{{ Infobox diagnosis
	\| Name = {{PAGENAME}}		\| Name = {{PAGENAME}}
	\| Image =		\| Image = Prostate carcinoma with NEC -- high mag.jpg
	\| Width =		\| Width =
	\| Caption =		\| Caption = Small cell carcinoma of the prostate. [[H&E stain]].
	\| Synonyms =		\| Synonyms =
	\| Micro = small cells with nuclear moulding, stippled chromatin and high [[NC ratio]], +/-high-grade acinar adenocarcinoma (common)		\| Micro = small cells with nuclear moulding, stippled chromatin and high [[NC ratio]], +/-high-grade acinar adenocarcinoma (common)
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	===Images===		===Images===
			====Case====
			<gallery>
			Image: Prostate carcinoma with NEC -- very low mag.jpg \| PCNEC - very low mag. (WC)
			Image: Prostate carcinoma with NEC -- low mag.jpg \| PCNEC - low mag. (WC)
			Image: Prostate carcinoma with NEC -- intermed mag.jpg \| PCNEC - intermed. mag. (WC)
			Image: Prostate carcinoma with NEC -- high mag.jpg \| PCNEC - high mag. (WC)

			Image: Prostate carcinoma with NEC - conv only -- low mag.jpg \| PCNEC - low mag. (WC)
			Image: Prostate carcinoma with NEC - conv only -- intermed mag.jpg \| PCNEC - intermed. mag. (WC)
			Image: Prostate carcinoma with NEC - conv only -- high mag.jpg \| PCNEC - high mag. (WC)
			</gallery>
	====www====		====www====
	*[http://www.webpathology.com/image.asp?case=23&n=25 SmCC of the prostate - low mag. (webpathology.com)].		*[http://www.webpathology.com/image.asp?case=23&n=25 SmCC of the prostate - low mag. (webpathology.com)].

Michael: +infobox

2016-01-24T04:41:27Z

+infobox

← Older revision		Revision as of 04:41, 24 January 2016
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			{{ Infobox diagnosis
			\| Name = {{PAGENAME}}
			\| Image =
			\| Width =
			\| Caption =
			\| Synonyms =
			\| Micro = small cells with nuclear moulding, stippled chromatin and high [[NC ratio]], +/-high-grade acinar adenocarcinoma (common)
			\| Subtypes =
			\| LMDDx = [[small cell carcinoma of the urinary bladder]], metastatic [[small cell carcinoma]], poorly differentiated [[prostate carcinoma]]
			\| Stains =
			\| IHC = chromogranin A +ve, PSA -ve/+ve
			\| EM =
			\| Molecular =
			\| IF =
			\| Gross =
			\| Grossing = [[prostate biopsy]], [[prostate chips]], [[radical prostatectomy]]
			\| Staging =
			\| Site = [[prostate gland]] - see ''[[prostate cancer]]''
			\| Assdx =
			\| Syndromes =
			\| Clinicalhx =
			\| Signs =
			\| Symptoms =
			\| Prevalence = rare
			\| Bloodwork =
			\| Rads =
			\| Endoscopy =
			\| Prognosis = poor
			\| Other =
			\| ClinDDx = other types of [[prostate cancer]], metastatic cancer
			\| Tx = chemotherapy
			}}
	'''Small cell carcinoma of the prostate gland''' is a rare type of [[prostate cancer]] with an aggressive course.		'''Small cell carcinoma of the prostate gland''' is a rare type of [[prostate cancer]] with an aggressive course.

Michael: /* See also */

2016-01-24T04:13:43Z

← Older revision		Revision as of 12:37, 8 December 2016
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	*[[Prostate cancer]].		*[[Prostate cancer]].
	*[[Small cell carcinoma]].		*[[Small cell carcinoma]].
			*[[Paneth cell-like change of the prostate gland]].

	==References==		==References==

← Older revision		Revision as of 04:13, 24 January 2016
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	==See also==		==See also==
	*[[Prostate cancer]].		*[[Prostate cancer]].
			*[[Small cell carcinoma]].

	==References==		==References==