Solitary fibrous tumour - Revision history

Jensflorian: /* Images */ STAT6 added.

2016-12-15T07:21:49Z

Images: STAT6 added.

← Older revision		Revision as of 07:21, 15 December 2016
Line 66:		Line 66:
	Image:Solitary_fibrous_tumour_intermed_mag.jpg \| Benign SFT - intermed. mag. (WC)		Image:Solitary_fibrous_tumour_intermed_mag.jpg \| Benign SFT - intermed. mag. (WC)
	Image:Solitary_fibrous_tumour_high_mag.jpg \| Benign SFT - high mag. (WC)		Image:Solitary_fibrous_tumour_high_mag.jpg \| Benign SFT - high mag. (WC)
			File:Neuropathology_case_VI_01.jpg \| Nuclear STAT6 immunoreactivity in malignant SFT (WC/jensflorian)
	</gallery>		</gallery>
	www:		www:
Line 77:		Line 78:
	File:3 18039322534203 sl 4.png\|malignant solitary fibrous tumor \| Nuclei, lacking organization, show varied size and shape, with some cells being round to ovoid. The arrow points to myxoid focus in stroma. When a majority of the following are present, a low to intermediate grade malignant solitary fibrous tumor is present: 1) size > 5 cm (this case), 2) pleomorphism with round cells/epithelioid cells (this case), 3) subcapsular hemorrhage (this case), 4) ≥4 mitoses per 10 high power fields, 5) necrosis with perivascular tumor sparing. STAT 6 positivity is very helpful in separating this tumor from its mimics		File:3 18039322534203 sl 4.png\|malignant solitary fibrous tumor \| Nuclei, lacking organization, show varied size and shape, with some cells being round to ovoid. The arrow points to myxoid focus in stroma. When a majority of the following are present, a low to intermediate grade malignant solitary fibrous tumor is present: 1) size > 5 cm (this case), 2) pleomorphism with round cells/epithelioid cells (this case), 3) subcapsular hemorrhage (this case), 4) ≥4 mitoses per 10 high power fields, 5) necrosis with perivascular tumor sparing. STAT 6 positivity is very helpful in separating this tumor from its mimics
	</gallery>		</gallery>


	==IHC==		==IHC==

Jensflorian: removed [[

2016-12-15T07:18:04Z

removed [[

← Older revision		Revision as of 07:18, 15 December 2016
Line 70:		Line 70:
	*[http://path.upmc.edu/cases/case272.html SFT of the brain - several images (upmc.edu)].		*[http://path.upmc.edu/cases/case272.html SFT of the brain - several images (upmc.edu)].

			Malignant solitary fibrous tumor (low to intermediate grade tumor). 15 cm mass in upper arm of 50 year old man.<ref>Am J Surg Pathol 2014;38:552-559</ref>
	<gallery>		<gallery>
	~~Malignant solitary fibrous tumor (low to intermediate grade tumor). 15 cm mass in upper arm of 50 year old man.<ref>Am J Surg Pathol 2014;38:552-559</ref>~~
	File:3 18039322534203 sl 1.png\|malignant solitary fibrous tumor \| Hypocellular (green arrow) and hypercellular (cyan arrow) areas alternate.		File:3 18039322534203 sl 1.png\|malignant solitary fibrous tumor \| Hypocellular (green arrow) and hypercellular (cyan arrow) areas alternate.
	File:3 18039322534203 sl 2.png\|malignant solitary fibrous tumor \| Vascular spaces suggest antlers (staghorn). Note subcapsular hemorrhage.		File:3 18039322534203 sl 2.png\|malignant solitary fibrous tumor \| Vascular spaces suggest antlers (staghorn). Note subcapsular hemorrhage.
	File:3 18039322534203 sl 3.png\|malignant solitary fibrous tumor \| Stromal hyalinization		File:3 18039322534203 sl 3.png\|malignant solitary fibrous tumor \| Stromal hyalinization
	[[File:3 18039322534203 sl 4.png\|malignant solitary fibrous tumor \| Nuclei, lacking organization, show varied size and shape, with some cells being round to ovoid. The arrow points to myxoid focus in stroma. When a majority of the following are present, a low to intermediate grade malignant solitary fibrous tumor is present: 1) size > 5 cm (this case), 2) pleomorphism with round cells/epithelioid cells (this case), 3) subcapsular hemorrhage (this case), 4) ≥4 mitoses per 10 high power fields, 5) necrosis with perivascular tumor sparing. STAT 6 positivity is very helpful in separating this tumor from its mimics		File:3 18039322534203 sl 4.png\|malignant solitary fibrous tumor \| Nuclei, lacking organization, show varied size and shape, with some cells being round to ovoid. The arrow points to myxoid focus in stroma. When a majority of the following are present, a low to intermediate grade malignant solitary fibrous tumor is present: 1) size > 5 cm (this case), 2) pleomorphism with round cells/epithelioid cells (this case), 3) subcapsular hemorrhage (this case), 4) ≥4 mitoses per 10 high power fields, 5) necrosis with perivascular tumor sparing. STAT 6 positivity is very helpful in separating this tumor from its mimics
	</gallery>		</gallery>

Jensflorian: reformatted. @Mitchell: Do you have the permission to re-use the images here? Am J Surg Pathol is not OpenAccess by default.

2016-12-15T07:14:12Z

reformatted. @Mitchell: Do you have the permission to re-use the images here? Am J Surg Pathol is not OpenAccess by default.

← Older revision		Revision as of 07:14, 15 December 2016
Line 70:		Line 70:
	*[http://path.upmc.edu/cases/case272.html SFT of the brain - several images (upmc.edu)].		*[http://path.upmc.edu/cases/case272.html SFT of the brain - several images (upmc.edu)].

	[[File:3 18039322534203 sl 1.png\|malignant solitary fibrous tumor]]		<gallery>
	[[File:3 18039322534203 sl 2.png\|malignant solitary fibrous tumor]]		Malignant solitary fibrous tumor (low to intermediate grade tumor). 15 cm mass in upper arm of 50 year old man.<ref>Am J Surg Pathol 2014;38:552-559</ref>
	[[File:3 18039322534203 sl 3.png\|malignant solitary fibrous tumor]]		File:3 18039322534203 sl 1.png\|malignant solitary fibrous tumor \| Hypocellular (green arrow) and hypercellular (cyan arrow) areas alternate.
	[[File:3 18039322534203 sl 4.png\|malignant solitary fibrous tumor]]		File:3 18039322534203 sl 2.png\|malignant solitary fibrous tumor \| Vascular spaces suggest antlers (staghorn). Note subcapsular hemorrhage.
			File:3 18039322534203 sl 3.png\|malignant solitary fibrous tumor \| Stromal hyalinization
			[[File:3 18039322534203 sl 4.png\|malignant solitary fibrous tumor \| Nuclei, lacking organization, show varied size and shape, with some cells being round to ovoid. The arrow points to myxoid focus in stroma. When a majority of the following are present, a low to intermediate grade malignant solitary fibrous tumor is present: 1) size > 5 cm (this case), 2) pleomorphism with round cells/epithelioid cells (this case), 3) subcapsular hemorrhage (this case), 4) ≥4 mitoses per 10 high power fields, 5) necrosis with perivascular tumor sparing. STAT 6 positivity is very helpful in separating this tumor from its mimics
			</gallery>

	Malignant solitary fibrous tumor (low to intermediate grade tumor). 15 cm mass in upper arm of 50 year old man. A. Hypocellular (green arrow) and hypercellular (cyan arrow) areas alternate. B. Vascular spaces suggest antlers (staghorn). Note subcapsular hemorrhage. C. Stromal hyalinization. D. Nuclei, lacking organization, show varied size and shape, with some cells being round to ovoid. The arrow points to myxoid focus in stroma. When a majority of the following are present, a low to intermediate grade malignant solitary fibrous tumor is present: 1) size > 5 cm (this case), 2) pleomorphism with round cells/epithelioid cells (this case), 3) subcapsular hemorrhage (this case), 4) ≥4 mitoses per 10 high power fields, 5) necrosis with perivascular tumor sparing. STAT 6 positivity is very helpful in separating this tumor from its mimics. <ref name=pmid24625420>{{cite journal \|author=Yoshida A1, Tsuta K, Ohno M, Yoshida M, Narita Y, Kawai A, Asamura H, Kushima R \|title=STAT6 immunohistochemistry is helpful in the diagnosis of solitary fibrous tumors \|journal=Am J Surg Pathol \|volume=38 \|issue=4 \|pages=552-559 \|year=2014 \|month=April \|pmid=24625420 \|doi=10.1097/PAS.0000000000000137}}</ref>

	==IHC==		==IHC==

Mitchell: /* Images */

2016-12-14T20:41:06Z

Images

← Older revision		Revision as of 20:41, 14 December 2016
Line 75:		Line 75:
	[[File:3 18039322534203 sl 4.png\|malignant solitary fibrous tumor]]		[[File:3 18039322534203 sl 4.png\|malignant solitary fibrous tumor]]

	Malignant solitary fibrous tumor (low to intermediate grade tumor). 15 cm mass in upper arm of 50 year old man. A. Hypocellular (green arrow) and hypercellular (cyan arrow) areas alternate. B. Vascular spaces suggest antlers (staghorn). Note subcapsular hemorrhage. C. Stromal hyalinization. D. Nuclei, lacking organization, show varied size and shape, with some cells being round to ovoid. The arrow points to myxoid focus in stroma. When a majority of the following are present, a low to intermediate grade malignant solitary fibrous tumor is present: 1) size > 5 cm (this case), 2) pleomorphism with round cells/epithelioid cells (this case), 3) subcapsular hemorrhage (this case), 4) ≥4 mitoses per 10 high power fields, 5) necrosis with perivascular tumor sparing. STAT 6 positivity is very helpful in separating this tumor from its mimics. Am J Surg Pathol ~~2014;~~38:552-559		Malignant solitary fibrous tumor (low to intermediate grade tumor). 15 cm mass in upper arm of 50 year old man. A. Hypocellular (green arrow) and hypercellular (cyan arrow) areas alternate. B. Vascular spaces suggest antlers (staghorn). Note subcapsular hemorrhage. C. Stromal hyalinization. D. Nuclei, lacking organization, show varied size and shape, with some cells being round to ovoid. The arrow points to myxoid focus in stroma. When a majority of the following are present, a low to intermediate grade malignant solitary fibrous tumor is present: 1) size > 5 cm (this case), 2) pleomorphism with round cells/epithelioid cells (this case), 3) subcapsular hemorrhage (this case), 4) ≥4 mitoses per 10 high power fields, 5) necrosis with perivascular tumor sparing. STAT 6 positivity is very helpful in separating this tumor from its mimics. <ref name=pmid24625420>{{cite journal \|author=Yoshida A1, Tsuta K, Ohno M, Yoshida M, Narita Y, Kawai A, Asamura H, Kushima R \|title=STAT6 immunohistochemistry is helpful in the diagnosis of solitary fibrous tumors \|journal=Am J Surg Pathol \|volume=38 \|issue=4 \|pages=552-559 \|year=2014 \|month=April \|pmid=24625420 \|doi=10.1097/PAS.0000000000000137}}</ref>

	==IHC==		==IHC==

Mitchell: /* Microscopic */

2016-12-14T20:24:46Z

Microscopic

← Older revision		Revision as of 20:24, 14 December 2016
Line 74:		Line 74:
	[[File:3 18039322534203 sl 3.png\|malignant solitary fibrous tumor]]		[[File:3 18039322534203 sl 3.png\|malignant solitary fibrous tumor]]
	[[File:3 18039322534203 sl 4.png\|malignant solitary fibrous tumor]]		[[File:3 18039322534203 sl 4.png\|malignant solitary fibrous tumor]]

	Malignant solitary fibrous tumor (low to intermediate grade tumor). 15 cm mass in upper arm of 50 year old man. A. Hypocellular (green arrow) and hypercellular (cyan arrow) areas alternate. B. Vascular spaces suggest antlers (staghorn). Note subcapsular hemorrhage. C. Stromal hyalinization. D. Nuclei, lacking organization, show varied size and shape, with some cells being round to ovoid. The arrow points to myxoid focus in stroma. When a majority of the following are present, a low to intermediate grade malignant solitary fibrous tumor is present: 1) size > 5 cm (this case), 2) pleomorphism with round cells/epithelioid cells (this case), 3) subcapsular hemorrhage (this case), 4) ≥4 mitoses per 10 high power fields, 5) necrosis with perivascular tumor sparing. STAT 6 positivity is very helpful in separating this tumor from its mimics. Am J Surg Pathol 2014;38:552-559		Malignant solitary fibrous tumor (low to intermediate grade tumor). 15 cm mass in upper arm of 50 year old man. A. Hypocellular (green arrow) and hypercellular (cyan arrow) areas alternate. B. Vascular spaces suggest antlers (staghorn). Note subcapsular hemorrhage. C. Stromal hyalinization. D. Nuclei, lacking organization, show varied size and shape, with some cells being round to ovoid. The arrow points to myxoid focus in stroma. When a majority of the following are present, a low to intermediate grade malignant solitary fibrous tumor is present: 1) size > 5 cm (this case), 2) pleomorphism with round cells/epithelioid cells (this case), 3) subcapsular hemorrhage (this case), 4) ≥4 mitoses per 10 high power fields, 5) necrosis with perivascular tumor sparing. STAT 6 positivity is very helpful in separating this tumor from its mimics. Am J Surg Pathol 2014;38:552-559

Mitchell: /* Images */ added a case

2016-12-14T20:19:53Z

Images: added a case

← Older revision		Revision as of 20:19, 14 December 2016
Line 69:		Line 69:
	www:		www:
	*[http://path.upmc.edu/cases/case272.html SFT of the brain - several images (upmc.edu)].		*[http://path.upmc.edu/cases/case272.html SFT of the brain - several images (upmc.edu)].

			[[File:3 18039322534203 sl 1.png\|malignant solitary fibrous tumor]]
			[[File:3 18039322534203 sl 2.png\|malignant solitary fibrous tumor]]
			[[File:3 18039322534203 sl 3.png\|malignant solitary fibrous tumor]]
			[[File:3 18039322534203 sl 4.png\|malignant solitary fibrous tumor]]
			Malignant solitary fibrous tumor (low to intermediate grade tumor). 15 cm mass in upper arm of 50 year old man. A. Hypocellular (green arrow) and hypercellular (cyan arrow) areas alternate. B. Vascular spaces suggest antlers (staghorn). Note subcapsular hemorrhage. C. Stromal hyalinization. D. Nuclei, lacking organization, show varied size and shape, with some cells being round to ovoid. The arrow points to myxoid focus in stroma. When a majority of the following are present, a low to intermediate grade malignant solitary fibrous tumor is present: 1) size > 5 cm (this case), 2) pleomorphism with round cells/epithelioid cells (this case), 3) subcapsular hemorrhage (this case), 4) ≥4 mitoses per 10 high power fields, 5) necrosis with perivascular tumor sparing. STAT 6 positivity is very helpful in separating this tumor from its mimics. Am J Surg Pathol 2014;38:552-559

	==IHC==		==IHC==

Jensflorian: grading

2015-09-24T10:31:19Z

grading

← Older revision		Revision as of 10:31, 24 September 2015
Line 38:		Line 38:
	*May be associated with hypoglycemia.		*May be associated with hypoglycemia.
	**Known as ''Doege-Potter syndrome''.<ref name=pmid1474302>{{Cite journal \| last1 = Roy \| first1 = TM. \| last2 = Burns \| first2 = MV. \| last3 = Overly \| first3 = DJ. \| last4 = Curd \| first4 = BT. \| title = Solitary fibrous tumor of the pleura with hypoglycemia: the Doege-Potter syndrome. \| journal = J Ky Med Assoc \| volume = 90 \| issue = 11 \| pages = 557-60 \| month = Nov \| year = 1992 \| doi = \| PMID = 1474302 }}</ref>		**Known as ''Doege-Potter syndrome''.<ref name=pmid1474302>{{Cite journal \| last1 = Roy \| first1 = TM. \| last2 = Burns \| first2 = MV. \| last3 = Overly \| first3 = DJ. \| last4 = Curd \| first4 = BT. \| title = Solitary fibrous tumor of the pleura with hypoglycemia: the Doege-Potter syndrome. \| journal = J Ky Med Assoc \| volume = 90 \| issue = 11 \| pages = 557-60 \| month = Nov \| year = 1992 \| doi = \| PMID = 1474302 }}</ref>
	*Leptomeningeal SFTs/hemangiopericytomas are classified as WHO grade II~~, anaplastic forms as~~ WHO grade III.		*Leptomeningeal SFTs/hemangiopericytomas are classified as follows:
			** WHO grade I: classical SFT
			** WHO grade II: classical [[hemangiopericytoma]]
			** WHO grade III: anaplastic hemangiopericytoma / malignant SFT

	==Gross==		==Gross==

Jensflorian: Update NAB2-STAT6 fusions as specific marker for SFT/hemangiopericytoma

2015-05-20T08:19:39Z

Update NAB2-STAT6 fusions as specific marker for SFT/hemangiopericytoma

← Older revision		Revision as of 08:19, 20 May 2015
Line 33:		Line 33:

	==General==		==General==
	*Grouped with ''hemangiopericytoma'' in the WHO classification - as it is thought to be the same tumour.<ref name=Ref_WMSP609>{{Ref WMSP\|609}}</ref>		*Grouped with ''hemangiopericytoma'' in the WHO classification - as it is thought to be the same tumour because both share the same molecular alteration.<ref name=Ref_WMSP609>{{Ref WMSP\|609}}</ref><ref>{{Cite journal \| last1 = Schweizer \| first1 = L. \| last2 = Koelsche \| first2 = C. \| last3 = Sahm \| first3 = F. \| last4 = Piro \| first4 = RM. \| last5 = Capper \| first5 = D. \| last6 = Reuss \| first6 = DE. \| last7 = Pusch \| first7 = S. \| last8 = Habel \| first8 = A. \| last9 = Meyer \| first9 = J. \| title = Meningeal hemangiopericytoma and solitary fibrous tumors carry the NAB2-STAT6 fusion and can be diagnosed by nuclear expression of STAT6 protein. \| journal = Acta Neuropathol \| volume = 125 \| issue = 5 \| pages = 651-8 \| month = May \| year = 2013 \| doi = 10.1007/s00401-013-1117-6 \| PMID = 23575898 }}</ref>

	*May be benign ''or'' malignant; more commonly benign.<ref>URL: [http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970528-9 http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970528-9]. Accessed on: 25 June 2010.</ref><ref>URL: [http://wjso.com/content/6/1/86 http://wjso.com/content/6/1/86]. Accessed on: 25 June 2010.</ref>		*May be benign ''or'' malignant; more commonly benign.<ref>URL: [http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970528-9 http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970528-9]. Accessed on: 25 June 2010.</ref><ref>URL: [http://wjso.com/content/6/1/86 http://wjso.com/content/6/1/86]. Accessed on: 25 June 2010.</ref>
	*May be associated with hypoglycemia.		*May be associated with hypoglycemia.
	**Known as ''Doege-Potter syndrome''.<ref name=pmid1474302>{{Cite journal \| last1 = Roy \| first1 = TM. \| last2 = Burns \| first2 = MV. \| last3 = Overly \| first3 = DJ. \| last4 = Curd \| first4 = BT. \| title = Solitary fibrous tumor of the pleura with hypoglycemia: the Doege-Potter syndrome. \| journal = J Ky Med Assoc \| volume = 90 \| issue = 11 \| pages = 557-60 \| month = Nov \| year = 1992 \| doi = \| PMID = 1474302 }}</ref>		**Known as ''Doege-Potter syndrome''.<ref name=pmid1474302>{{Cite journal \| last1 = Roy \| first1 = TM. \| last2 = Burns \| first2 = MV. \| last3 = Overly \| first3 = DJ. \| last4 = Curd \| first4 = BT. \| title = Solitary fibrous tumor of the pleura with hypoglycemia: the Doege-Potter syndrome. \| journal = J Ky Med Assoc \| volume = 90 \| issue = 11 \| pages = 557-60 \| month = Nov \| year = 1992 \| doi = \| PMID = 1474302 }}</ref>
			*Leptomeningeal SFTs/hemangiopericytomas are classified as WHO grade II, anaplastic forms as WHO grade III.

	==Gross==		==Gross==
Line 69:		Line 71:
	*CD99 ~70% +ve.		*CD99 ~70% +ve.
	*BCL2 ~50% +ve.		*BCL2 ~50% +ve.
			*Stat6 nuclear +ve.<ref>{{Cite journal \| last1 = Cheah \| first1 = AL. \| last2 = Billings \| first2 = SD. \| last3 = Goldblum \| first3 = JR. \| last4 = Carver \| first4 = P. \| last5 = Tanas \| first5 = MZ. \| last6 = Rubin \| first6 = BP. \| title = STAT6 rabbit monoclonal antibody is a robust diagnostic tool for the distinction of solitary fibrous tumour from its mimics. \| journal = Pathology \| volume = 46 \| issue = 5 \| pages = 389-95 \| month = Aug \| year = 2014 \| doi = 10.1097/PAT.0000000000000122 \| PMID = 24977739 }}</ref>

			==Molecular==
			*NAB2/STAT6 fusions.<ref>{{Cite journal \| last1 = Mohajeri \| first1 = A. \| last2 = Tayebwa \| first2 = J. \| last3 = Collin \| first3 = A. \| last4 = Nilsson \| first4 = J. \| last5 = Magnusson \| first5 = L. \| last6 = von Steyern \| first6 = FV. \| last7 = Brosjö \| first7 = O. \| last8 = Domanski \| first8 = HA. \| last9 = Larsson \| first9 = O. \| title = Comprehensive genetic analysis identifies a pathognomonic NAB2/STAT6 fusion gene, nonrandom secondary genomic imbalances, and a characteristic gene expression profile in solitary fibrous tumor. \| journal = Genes Chromosomes Cancer \| volume = 52 \| issue = 10 \| pages = 873-86 \| month = Oct \| year = 2013 \| doi = 10.1002/gcc.22083 \| PMID = 23761323 }}</ref><ref>{{Cite journal \| last1 = Robinson \| first1 = DR. \| last2 = Wu \| first2 = YM. \| last3 = Kalyana-Sundaram \| first3 = S. \| last4 = Cao \| first4 = X. \| last5 = Lonigro \| first5 = RJ. \| last6 = Sung \| first6 = YS. \| last7 = Chen \| first7 = CL. \| last8 = Zhang \| first8 = L. \| last9 = Wang \| first9 = R. \| title = Identification of recurrent NAB2-STAT6 gene fusions in solitary fibrous tumor by integrative sequencing. \| journal = Nat Genet \| volume = 45 \| issue = 2 \| pages = 180-5 \| month = Feb \| year = 2013 \| doi = 10.1038/ng.2509 \| PMID = 23313952 }}</ref>

			==DDx==
			*[[Meningioma]]
			*Cellular [[angiofibroma]]
			*[[Myofibroblastoma]]
			*Benign [[fibrous histiocytoma]]
			*[[Dermatofibrosarcoma protruberans]]
			*[[Fibromyxoid sarcoma]]

	==See also==		==See also==
	*[[Fibroblastic/myofibroblastic tumours]].		*[[Fibroblastic/myofibroblastic tumours]].
			*[[Hemangiopericytoma]]

	==References==		==References==
Line 78:		Line 93:
	[[Category:Fibroblastic/myofibroblastic tumours]]		[[Category:Fibroblastic/myofibroblastic tumours]]
	[[Category:Diagnosis]]		[[Category:Diagnosis]]
			[[Category:Neuropathology]]

Michael: /* Microscopic */

2014-02-18T15:44:30Z

Microscopic

← Older revision		Revision as of 15:44, 18 February 2014
Line 44:		Line 44:
	Features - benign:		Features - benign:
	*Spindle cells in a patternless pattern.		*Spindle cells in a patternless pattern.
			**Occasionally epithelioid cells - rare.<ref name=pmid17577399>{{Cite journal \| last1 = Martorell \| first1 = M. \| last2 = Pérez-Vallés \| first2 = A. \| last3 = Gozalbo \| first3 = F. \| last4 = Garcia-Garcia \| first4 = JA. \| last5 = Gutierrez \| first5 = J. \| last6 = Gaona \| first6 = J. \| title = Solitary fibrous tumor of the thigh with epithelioid features: a case report. \| journal = Diagn Pathol \| volume = 2 \| issue = \| pages = 19 \| month = \| year = 2007 \| doi = 10.1186/1746-1596-2-19 \| PMID = 17577399 }}</ref>
	*Hemangiopericytoma-like area ([[staghorn vessels]]).		*Hemangiopericytoma-like area ([[staghorn vessels]]).
	*Keloid-like collagen bundles - '''key feature'''.		*Keloid-like collagen bundles - '''key feature'''.

Michael at 03:41, 18 February 2014

2014-02-18T03:41:11Z

← Older revision		Revision as of 03:41, 18 February 2014
Line 29:		Line 29:
	}}		}}
	'''Solitary fibrous tumour''', abbreviated '''SFT''', is a type of [[soft tissue lesion\|soft tissue tumour]] that fits in the [[fibroblastic/myofibroblastic tumours]]. It is usually benign.		'''Solitary fibrous tumour''', abbreviated '''SFT''', is a type of [[soft tissue lesion\|soft tissue tumour]] that fits in the [[fibroblastic/myofibroblastic tumours]]. It is usually benign.

			SFT of the pleura is dealt with in a separate article ''[[solitary fibrous tumour of the pleura]]''.

	==General==		==General==
Line 37:		Line 39:

	==Gross==		==Gross==
	*~~Classically arise from the pleura - see ''[[solitary fibrous tumour of the pleura]]''~~.		*Soft tissue mass.

	==Microscopic==		==Microscopic==