Solitary rectal ulcer - Revision history

Michael: /* Verbose form */

2020-12-23T20:40:14Z

Verbose form

← Older revision		Revision as of 20:40, 23 December 2020
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	Comment:		Comment:
	The findings are compatible solitary rectal ulcer/mucosal prolapse in		The findings are compatible with solitary rectal ulcer/mucosal prolapse in
	the proper endoscopic context.		the proper endoscopic context.
	</pre>		</pre>

Michael: /* IHC */

2020-12-23T20:39:25Z

IHC

← Older revision		Revision as of 20:39, 23 December 2020
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	*p53 -ve.		*p53 -ve.
	**May be used to help exclude adenocarcinoma.		**May be used to help exclude adenocarcinoma.

			==Sign out==
			===Verbose form===
			<pre>
			Rectum, Biopsy:
			- Colonic mucosa with mild active inflammation, ulceration,
			fibromuscular hyperplasia and necro-inflammatory debris.
			- NEGATIVE for dysplasia and NEGATIVE for evidence of malignancy.

			Comment:
			The findings are compatible solitary rectal ulcer/mucosal prolapse in
			the proper endoscopic context.
			</pre>

	==See also==		==See also==

Michael at 23:18, 28 May 2015

2015-05-28T23:18:02Z

← Older revision		Revision as of 23:18, 28 May 2015
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	'''Solitary rectal ulcer''' is a benign disease of the ~~colorectum~~.		'''Solitary rectal ulcer''' is a benign disease of the [[colon\|colo]][[rectum]].

	It is also known as ''solitary ulcer syndrome of the rectum'' (abbreviated ''SUS'') and ''solitary rectal ulcer syndrome''.		It is also known as ''solitary ulcer syndrome of the rectum'' (abbreviated ''SUS'') and ''solitary rectal ulcer syndrome''.
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	==General==		==General==
	*Clinically may be suspected to a malignancy - biopsied routinely.		*Clinically may be suspected to a [[colorectal carcinoma\|malignancy]] - biopsied routinely.
	*Mucosal ulceration.		*Mucosal ulceration.
	*"Three-lies disease":<ref name=pmid18271667>{{cite journal \|author=Crespo Pérez L, Moreira Vicente V, Redondo Verge C, López San Román A, Milicua Salamero JM \|title=["The three-lies disease": solitary rectal ulcer syndrome] \|language=Spanish; Castilian \|journal=Rev Esp Enferm Dig \|volume=99 \|issue=11 \|pages=663–6 \|year=2007 \|month=November \|pmid=18271667 \|doi= \|url=http://www.grupoaran.com/mrmUpdate/lecturaPDFfromXML.asp?IdArt=459864&TO=RVN&Eng=1}}</ref>		*"Three-lies disease":<ref name=pmid18271667>{{cite journal \|author=Crespo Pérez L, Moreira Vicente V, Redondo Verge C, López San Román A, Milicua Salamero JM \|title=["The three-lies disease": solitary rectal ulcer syndrome] \|language=Spanish; Castilian \|journal=Rev Esp Enferm Dig \|volume=99 \|issue=11 \|pages=663–6 \|year=2007 \|month=November \|pmid=18271667 \|doi= \|url=http://www.grupoaran.com/mrmUpdate/lecturaPDFfromXML.asp?IdArt=459864&TO=RVN&Eng=1}}</ref>

Michael: /* References */

2015-05-28T23:15:51Z

References

← Older revision		Revision as of 23:15, 28 May 2015
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	[[Category:Diagnosis]]		[[Category:Diagnosis]]
	[[Category:~~Rectum~~]].		[[Category:Colon]]

Michael: split out

2015-05-28T23:11:43Z

split out

← Older revision		Revision as of 23:11, 28 May 2015
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	~~#redirect~~ [[~~Colon~~#Solitary rectal ulcer]]		'''Solitary rectal ulcer''' is a benign disease of the colorectum.

			It is also known as ''solitary ulcer syndrome of the rectum'' (abbreviated ''SUS'') and ''solitary rectal ulcer syndrome''.

			''[[Mucosal prolapse syndrome]]'' may be used as a synonym; however, it encompasses other entities.<ref name=pmid22697798>{{Cite journal \| last1 = Abid \| first1 = S. \| last2 = Khawaja \| first2 = A. \| last3 = Bhimani \| first3 = SA. \| last4 = Ahmad \| first4 = Z. \| last5 = Hamid \| first5 = S. \| last6 = Jafri \| first6 = W. \| title = The clinical, endoscopic and histological spectrum of the solitary rectal ulcer syndrome: a single-center experience of 116 cases. \| journal = BMC Gastroenterol \| volume = 12 \| issue = \| pages = 72 \| month = \| year = 2012 \| doi = 10.1186/1471-230X-12-72 \| PMID = 22697798 }}</ref>

			==General==
			*Clinically may be suspected to a malignancy - biopsied routinely.
			*Mucosal ulceration.
			*"Three-lies disease":<ref name=pmid18271667>{{cite journal \|author=Crespo Pérez L, Moreira Vicente V, Redondo Verge C, López San Román A, Milicua Salamero JM \|title=["The three-lies disease": solitary rectal ulcer syndrome] \|language=Spanish; Castilian \|journal=Rev Esp Enferm Dig \|volume=99 \|issue=11 \|pages=663–6 \|year=2007 \|month=November \|pmid=18271667 \|doi= \|url=http://www.grupoaran.com/mrmUpdate/lecturaPDFfromXML.asp?IdArt=459864&TO=RVN&Eng=1}}</ref>
			# May not be solitary.
			# May not be rectal -- can be in left colon.
			# May not be ulcerating -- non-ulcerated lesions: polypoid and/or erythematous.

			Note: Each of the words in ''solitary rectal ulcer'' is a lie.

			===Epidemiology===
			*Typically younger patients - average age of presentation ~30 years in one study.<ref name=pmid17139403>{{cite journal \|author=Chong VH, Jalihal A \|title=Solitary rectal ulcer syndrome: characteristics, outcomes and predictive profiles for persistent bleeding per rectum \|journal=Singapore Med J \|volume=47 \|issue=12 \|pages=1063–8 \|year=2006 \|month=December \|pmid=17139403 \|doi= \|url=http://www.sma.org.sg/smj/4712/4712a7.pdf}}</ref>
			*Rare.

			===Clinical presentation===
			*Usually presents as [[BRBPR]] ~ 85% of cases.<ref name=pmid17139403/>
			*Abdominal pain present in approx. 1/3.<ref name=pmid17139403/>
			**May be very painful.

			Treatment:
			*Usually conservative, i.e. non-surgical.
			*Resection - may be done for fear of malignancy.

			==Gross==
			*Classically, anterior or anterolateral wall of the rectum.<ref name=pmid18271667/>

			==Microscopic==
			Features:<ref name=pmid18271667/><ref name=pmid2091997>{{Cite journal \| last1 = Malik \| first1 = AK. \| last2 = Bhaskar \| first2 = KV. \| last3 = Kochhar \| first3 = R. \| last4 = Bhasin \| first4 = DK. \| last5 = Singh \| first5 = K. \| last6 = Mehta \| first6 = SK. \| last7 = Datta \| first7 = BN. \| title = Solitary ulcer syndrome of the rectum--a histopathologic characterisation of 33 biopsies. \| journal = Indian J Pathol Microbiol \| volume = 33 \| issue = 3 \| pages = 216-20 \| month = Jul \| year = 1990 \| doi = \| PMID = 2091997 }}</ref>
			*Fibrosis of the lamina propria.
			*Thickened muscularis mucosa with abnormal extension to the lumen.
			*+/-Mucosa ulceration.
			*+/-Submucosal fibrosis.

			DDx:
			*[[Inflammatory pseudopolyp]] (inflammatory polyp).
			**Associated with [[inflammatory bowel disease]].
			*[[Rectal prolapse]].
			*Well-differentiated [[colonic adenocarcinoma\|adenocarcinoma]].

			==IHC==
			*p53 -ve.
			**May be used to help exclude adenocarcinoma.

			==See also==
			*[[Colon]].
			*[[Rectum]].

			==References==
			{{Reflist\|2}}

	[[Category:Diagnosis]]		[[Category:Diagnosis]]
			[[Category:Rectum]].

Michael: +cat.

2011-10-22T23:42:32Z

+cat.

← Older revision		Revision as of 23:42, 22 October 2011
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	#redirect [[Colon#Solitary rectal ulcer]]		#redirect [[Colon#Solitary rectal ulcer]]

			[[Category:Diagnosis]]

Michael: redirect for now

2011-03-01T14:08:08Z

redirect for now

New page

#redirect [[Colon#Solitary rectal ulcer]]