Spindle cell lesions - Revision history

Michael: /* See also */

2017-06-18T15:44:47Z

2017-03-05T15:44:38Z

2016-07-31T19:37:49Z

← Older revision		Revision as of 19:37, 31 July 2016
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	*SMA.		*SMA.
	*[[S-100]].		*[[S-100]].
	*AE1/AE3 (pankeratin).		*[[AE1/AE3]] (pankeratin).

	Memory device ''SCADS'' or ''CAD SS'' = S-100, CD34, AE1/AE3, Desmin, SMA.		Memory device ''SCADS'' or ''CAD SS'' = S-100, CD34, AE1/AE3, Desmin, SMA.

2016-05-27T17:23:54Z

← Older revision		Revision as of 17:23, 27 May 2016
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	*Caldesmon - muscle.		*Caldesmon - muscle.
	*PDGFR - [[GIST]]		*PDGFR - [[GIST]]
	*~~DOG-1~~ - GIST (membranous, cytoplasmic),<ref name=pmid19417627>{{cite journal \|author=Ardeleanu C, Arsene D, Hinescu M, ''et al.'' \|title=Pancreatic expression of DOG1: a novel gastrointestinal stromal tumor (GIST) biomarker \|journal=Appl. Immunohistochem. Mol. Morphol. \|volume=17 \|issue=5 \|pages=413–8 \|year=2009 \|month=October \|pmid=19417627 \|doi=10.1097/PAI.0b013e31819e4dc5 \|url=}}</ref> normal pancreas (islets),<ref name=pmid19417627/> associated with [[BRCA1]].		*[[DOG1]] - GIST (membranous, cytoplasmic),<ref name=pmid19417627>{{cite journal \|author=Ardeleanu C, Arsene D, Hinescu M, ''et al.'' \|title=Pancreatic expression of DOG1: a novel gastrointestinal stromal tumor (GIST) biomarker \|journal=Appl. Immunohistochem. Mol. Morphol. \|volume=17 \|issue=5 \|pages=413–8 \|year=2009 \|month=October \|pmid=19417627 \|doi=10.1097/PAI.0b013e31819e4dc5 \|url=}}</ref> normal pancreas (islets),<ref name=pmid19417627/> associated with [[BRCA1]].

	Others:		Others:

2016-03-13T21:45:33Z

A long differential diagnosis of spindle cell tumours

← Older revision		Revision as of 21:45, 13 March 2016
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	\| [[Sclerotic "plywood" fibroma]]		\| [[Sclerotic "plywood" fibroma]]
	\| fibroblastic/myofibroblastic tumours		\| fibroblastic/myofibroblastic tumours
	\|		\| <ref>{{Cite journal \| last1 = Hanft \| first1 = VN. \| last2 = Shea \| first2 = CR. \| last3 = McNutt \| first3 = NS. \| last4 = Pullitzer \| first4 = D. \| last5 = Horenstein \| first5 = MG. \| last6 = Prieto \| first6 = VG. \| title = Expression of CD34 in sclerotic ("plywood") fibromas. \| journal = Am J Dermatopathol \| volume = 22 \| issue = 1 \| pages = 17-21 \| month = Feb \| year = 2000 \| doi = \| PMID = 10698210 }}</ref>
	\|-		\|-
	\| [[Fibrosarcoma]]		\| [[Fibrosarcoma]]

2016-02-25T13:43:13Z

← Older revision		Revision as of 13:43, 25 February 2016
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	'''[[Spindle cell]] lesions''' are seen frequent enough that one ought to have a solid approach to 'em.		'''[[Spindle cell]] lesions''' are seen frequent enough that one ought to have a solid approach to 'em.

	A general introduction to ''spindle cells'' is found in the [[spindle cell]] article.		A general introduction to ''spindle cells'' is found in the ''[[spindle cell]]'' article.

	==General DDx==		==General DDx==

2016-02-25T13:42:19Z

← Older revision		Revision as of 13:42, 25 February 2016
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	[[Image:Malignant_peripheral_nerve_sheath_tumour_-_very_high_mag.jpg\|thumb\|right\|250px\|A spindle cell lesion ([[MPNST]]). [[H&E stain]].]]		[[Image:Malignant_peripheral_nerve_sheath_tumour_-_very_high_mag.jpg\|thumb\|right\|250px\|A spindle cell lesion ([[MPNST]]). [[H&E stain]].]]
	'''[[Spindle cell]] lesions''' are seen frequent enough that one ought to have a solid approach to 'em.		'''[[Spindle cell]] lesions''' are seen frequent enough that one ought to have a solid approach to 'em.

			A general introduction to ''spindle cells'' is found in the [[spindle cell]] article.

	==General DDx==		==General DDx==

2015-11-04T16:00:24Z

← Older revision		Revision as of 16:00, 4 November 2015
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	*Desmin.		*Desmin.
	*SMA.		*SMA.
	*~~S100~~.		*[[S-100]].
	*AE1/AE3 (pankeratin).		*AE1/AE3 (pankeratin).

	Memory device ''SCADS'' or ''CAD SS'' = ~~S100~~, CD34, AE1/AE3, Desmin, SMA.		Memory device ''SCADS'' or ''CAD SS'' = S-100, CD34, AE1/AE3, Desmin, SMA.

	===Big panels===		===Big panels===
	====A MSH MFH panel====		====A MSH MFH panel====
	*CD34 - [[GIST]], [[angiosarcoma]], [[solitary fibrous tumour]]/[[hemangiopericytoma]], [[Kaposi sarcoma]], [[DFSP]], [[PASH]].		*CD34 - [[GIST]], [[angiosarcoma]], [[solitary fibrous tumour]]/[[hemangiopericytoma]], [[Kaposi sarcoma]], [[DFSP]], [[PASH]].
	*~~S100~~ - neural marker, sensitive for [[malignant melanoma]], Langerhans cells, [[clear cell sarcoma]].		*S-100 - neural marker, sensitive for [[malignant melanoma]], Langerhans cells, [[clear cell sarcoma]].
	*Desmin - smooth muscle.		*Desmin - smooth muscle.
	*MIB1 - proliferation.		*MIB1 - proliferation.

2014-11-19T16:56:37Z

touch

← Older revision		Revision as of 16:56, 19 November 2014
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	[[Image:Malignant_peripheral_nerve_sheath_tumour_-_very_high_mag.jpg\|thumb\|right\|250px\|A spindle cell lesion ([[MPNST]]). [[H&E stain]].]]		[[Image:Malignant_peripheral_nerve_sheath_tumour_-_very_high_mag.jpg\|thumb\|right\|250px\|A spindle cell lesion ([[MPNST]]). [[H&E stain]].]]
	'''[[Spindle cell]] lesions''' are seen frequent enough that one ought to have a solid approach to 'em.		'''[[Spindle cell]] lesions''' are seen frequent enough that one ought to have a solid approach to 'em.

	==General DDx==		==General DDx==

2014-11-01T06:57:07Z

← Older revision		Revision as of 06:57, 1 November 2014
Line 1:		Line 1:
			[[Image:Malignant_peripheral_nerve_sheath_tumour_-_very_high_mag.jpg\|thumb\|right\|250px\|A spindle cell lesion ([[MPNST]]). [[H&E stain]].]]
	'''[[Spindle cell]] lesions''' are seen frequent enough that one ought to have a solid approach to 'em.		'''[[Spindle cell]] lesions''' are seen frequent enough that one ought to have a solid approach to 'em.

← Older revision		Revision as of 15:44, 18 June 2017
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	*[[Spindle cell]].		*[[Spindle cell]].
	*[[Epithelioid cell lesions]].		*[[Epithelioid cell lesions]].
			*[[Spindle cell lesions of the skin]].

	==Treatment==		==Treatment==